| Tag | Content |
|---|---|
| Uniprot ID | P24530; A2A2Z8; A8K3T4; O15343; Q59GB1; Q5W0G9; Q8NHM6; Q8NHM7; Q8NHM8; Q8NHM9; Q9UD23; Q9UQK3; |
| Entrez ID | 1910 |
| Genbank protein ID | AAH14472.1; CAD30648.1; AAD24541.1; AAB25531.1; BAA14398.1; BAD92435.1; CAD30646.1; BAA02445.1; AAA58465.1; AAS38516.1; CAD30645.1; CAA67623.1; AAA52342.1; AAB19411.1; EAW80575.1; CAD30647.1; BAF83388.1; AAP32295.1; EAW80573.1; |
| Genbank nucleotide ID | NM_003991.3; NM_001201397.1; NM_001122659.2; NM_000115.4; |
| Ensembl protein ID | ENSP00000493527; ENSP00000487082; ENSP00000494278; ENSP00000493895; ENSP00000366416; ENSP00000486202; |
| Ensembl nucleotide ID | ENSG00000136160 |
| Gene name | Endothelin receptor type B |
| Gene symbol | EDNRB |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Sequence | MQPPPSLCGR ALVALVLACG LSRIWGEERG FPPDRATPLL QTAEIMTPPT KTLWPKGSNA 60 SLARSLAPAE VPKGDRTAGS PPRTISPPPC QGPIEIKETF KYINTVVSCL VFVLGIIGNS 120 TLLRIIYKNK CMRNGPNILI ASLALGDLLH IVIDIPINVY KLLAEDWPFG AEMCKLVPFI 180 QKASVGITVL SLCALSIDRY RAVASWSRIK GIGVPKWTAV EIVLIWVVSV VLAVPEAIGF 240 DIITMDYKGS YLRICLLHPV QKTAFMQFYK TAKDWWLFSF YFCLPLAITA FFYTLMTCEM 300 LRKKSGMQIA LNDHLKQRRE VAKTVFCLVL VFALCWLPLH LSRILKLTLY NQNDPNRCEL 360 LSFLLVLDYI GINMASLNSC INPIALYLVS KRFKNCFKSC LCCWCQSFEE KQSLEEKQSC 420 LKFKANDHGY DNFRSSNKYS SS 442 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.