| Tag | Content |
|---|---|
| Uniprot ID | P25101; B2R723; B4E2V6; B7Z9G6; D3DP03; E7ER36; O43441; Q16432; Q16433; Q8TBH2; |
| Entrez ID | 1909 |
| Genbank protein ID | AAB94859.1; AAB36327.1; AAQ87880.1; BAA14359.1; AAB20278.1; AAB25530.2; BAG65268.1; CAA43953.1; AAB36326.1; BAH14302.1; AAH22511.1; EAX05019.1; AAP32294.1; AAB23644.1; AAB25212.1; AAB36325.1; AAA58447.1; AAB20407.1; EAX05021.1; BAA01920.1; BAG35670.1; |
| Genbank nucleotide ID | NM_001957.3; NM_001166055.1; NM_001256283.1; |
| Ensembl protein ID | ENSP00000351359; ENSP00000496976; ENSP00000425354; ENSP00000425281; ENSP00000315011; ENSP00000498969; ENSP00000427259; |
| Ensembl nucleotide ID | ENSG00000151617 |
| Gene name | Endothelin-1 receptor |
| Gene symbol | EDNRA |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. |
| Sequence | METLCLRASF WLALVGCVIS DNPERYSTNL SNHVDDFTTF RGTELSFLVT THQPTNLVLP 60 SNGSMHNYCP QQTKITSAFK YINTVISCTI FIVGMVGNAT LLRIIYQNKC MRNGPNALIA 120 SLALGDLIYV VIDLPINVFK LLAGRWPFDH NDFGVFLCKL FPFLQKSSVG ITVLNLCALS 180 VDRYRAVASW SRVQGIGIPL VTAIEIVSIW ILSFILAIPE AIGFVMVPFE YRGEQHKTCM 240 LNATSKFMEF YQDVKDWWLF GFYFCMPLVC TAIFYTLMTC EMLNRRNGSL RIALSEHLKQ 300 RREVAKTVFC LVVIFALCWF PLHLSRILKK TVYNEMDKNR CELLSFLLLM DYIGINLATM 360 NSCINPIALY FVSKKFKNCF QSCLCCCCYQ SKSLMTSVPM NGTSIQWKNH DQNNHNTDRS 420 SHKDSMN 427 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.