Gene: GRB2

Basic information

Tag Content
Uniprot ID P62993; P29354; Q14450; Q63057; Q63059;
Entrez ID 2885
Genbank protein ID AAA58448.1; AAM21073.1; CAG46740.1; CAA44664.1; AAC37549.1; AAH00631.1; AAC72075.1;
Genbank nucleotide ID NM_002086.4; NM_203506.2;
Ensembl protein ID ENSP00000339007; ENSP00000496913; ENSP00000376346; ENSP00000376347; ENSP00000317360; ENSP00000376345;
Ensembl nucleotide ID ENSG00000177885
Gene name Growth factor receptor-bound protein 2
Gene symbol GRB2
Organism Homo sapiens
NCBI taxa ID 9606
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Sequence
MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW 60
FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL 120
WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQVPQQPTY VQALFDFDPQ EDGELGFRRG 180
DFIHVMDNSD PNWWKGACHG QTGMFPRNYV TPVNRNV 217

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Gene expression information

Gene expression in different tissues (GTEx V7)