Tag | Content |
---|---|
Uniprot ID | P62993; P29354; Q14450; Q63057; Q63059; |
Entrez ID | 2885 |
Genbank protein ID | AAA58448.1; AAM21073.1; CAG46740.1; CAA44664.1; AAC37549.1; AAH00631.1; AAC72075.1; |
Genbank nucleotide ID | NM_002086.4; NM_203506.2; |
Ensembl protein ID | ENSP00000339007; ENSP00000496913; ENSP00000376346; ENSP00000376347; ENSP00000317360; ENSP00000376345; |
Ensembl nucleotide ID | ENSG00000177885 |
Gene name | Growth factor receptor-bound protein 2 |
Gene symbol | GRB2 |
Organism | Homo sapiens |
NCBI taxa ID | 9606 |
Cleft type | |
Developmental stage | |
Data sources | Homology search |
Reference | |
Functional description | Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. |
Sequence | MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW 60 FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL 120 WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQVPQQPTY VQALFDFDPQ EDGELGFRRG 180 DFIHVMDNSD PNWWKGACHG QTGMFPRNYV TPVNRNV 217 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.