| Tag | Content |
|---|---|
| Uniprot ID | Q06141 |
| Entrez ID | 5068 |
| Genbank protein ID | BAA02728.1; AAA60020.1; AAH36776.1; AAA36415.1; AAB24642.1; CAA48605.1; |
| Genbank nucleotide ID | NM_138938.2; NM_002580.2; NM_138937.2; |
| Ensembl protein ID | ENSP00000386630; ENSP00000377456; ENSP00000304311; |
| Ensembl nucleotide ID | ENSG00000172016 |
| Gene name | Regenerating islet-derived protein 3-alpha |
| Gene symbol | REG3A |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 26449438 |
| Functional description | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. |
| Sequence | MLPPMALPSV SWMLLSCLML LSQVQGEEPQ RELPSARIRC PKGSKAYGSH CYALFLSPKS 60 WTDADLACQK RPSGNLVSVL SGAEGSFVSS LVKSIGNSYS YVWIGLHDPT QGTEPNGEGW 120 EWSSSDVMNY FAWERNPSTI SSPGHCASLS RSTAFLRWKD YNCNVRLPYV CKFTD 175 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.