| Tag | Content |
|---|---|
| Uniprot ID | Q62059; Q62058; Q9CUU0; |
| Entrez ID | |
| Genbank protein ID | BAB29411.3; BAA03796.1; BAA06802.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Versican core protein |
| Gene symbol | Vcan |
| Organism | Mus musculus |
| NCBI taxa ID | 10090 |
| Cleft type | CPO |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 21041365 |
| Functional description | May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. |
| Sequence | MLINMKGILW MCSTLLLTHA LHQAKMETSP PVKGSLSGKV VLPCHFSTLP TLPPNYNTSE 60 FLRIKWSKME VDKNGKDIKE TTVLVAQNGN IKIGQDYKGR VSVPTHPDDV GDASLTMVKL 120 RASDAAVYRC DVMYGIEDTQ DTMSLAVDGV VFHYRAATSR YTLNFAAAQQ ACLDIGAVIA 180 SPEQLFAAYE DGFEQCDAGW LSDQTVRYPI RAPREGCYGD MMGKEGVRTY GFRSPQETYD 240 VYCYVDHLDG DVFHITAPSK FTFEEAEAEC TSRDARLATV GELQAAWRNG FDQCDYGWLS 300 DASVRHPVTV ARAQCGGGLL GVRTLYRFEN QTCFPLPDSR FDAYCFKPKQ NISEATTIEM 360 NILAETSSPS LSKEPHMVPD RATPVIPLAT ELPIFTTHFP PAGNIVNSEQ KSVVYSQAIT 420 GRLATESPTT TRNTINSWDL NDSLASGSGP LGMPDISEIK EEELRSTTVI SQHATGSQAV 480 ITEDTQTHES VSQIEQIEVG PLVTSMEITN HISLKELPEK NKTPYESTEV TLEHTTEMPT 540 VSASPELATT SHYGFTLRED DREDRTLTVR SDQSTRVFSQ IPEVITVSKT SEDTTYSQLG 600 DLESISTSTI TMLGTDRSLI DKEKEPKTNG KVTEDEFGQS QPTTTFPSQH LTEVELLPYS 660 GDTTSVEGIS TVIYPSLQTD VTQGRERTET PRPELKKDPY TVDEIPEKVT KDPFIGKTEE 720 VFSGMPLSTS SSESSVERTE SVSPALTIEK LTGKPTEARD VEEMTTLTRL ETDVTKSDKD 780 VTRVHLTHST LNVEVVTVSK WPGDEDNSTS KPLPSTEHAG FTKLPPVPLS TIGINGKDKE 840 IPSFTDGGGE YTLFPDGTPK PLEKVSEEDL ASGELTVTFH TSTSIGSAEK SASGEPTTGD 900 RFLPTTSTED QVINATAEGS ALGEDTEASK PLFTGPPFVH TSDVEELAFV NYSSTQEPTT 960 YVDISHTSPL SIIPKTEWSV LETSVPLEDE ILGKSDQDIL EQTHLEATMS PGALRTTGVS 1020 QGETQEEPQT PGSPFPTFSS TAVMAKETTA FEEGEGSTYT PSEGRLMTGS ERVPGLETTP 1080 VGTSYPPGAI TDQEVEMDTM VTLMSTIRPT VVSSTESEVI YEAEGSSPTE FASTLRPFQT 1140 HVTQLMEETT EEGKKASLDY TDLGSGLFEP RATELPKFPS TPSDISVFTA IDSLHRTPPL 1200 SPSSSFTEEQ RVFEEESSEK TTGDILPGES VTQHPVTTLI DIVAMKTESD IDHMTSKPPV 1260 TQPTRPSVVE RKTTSKTQEL STSTPAAGTK FHPDINVYII EVRENKTGRL SDMIVSGHPI 1320 DSESKEEEPC SEETDPLHDL FAEILPELPD SFEIDIYHSE EDEDGEEDCV NATDVTTTPS 1380 VQYINGKQLV TTVPKDPEAA EARRGQYESV APSQNFPDSS ATDTHQFILA ETESSTTMQF 1440 KKSKEGTELL EITWKPETYP ETPDHVSSGE PDVFPTLSSH DGKTTRWSES ITESSPNLEN 1500 PVHKQPKPVP LFPEESSGEG AIEQASQETI LSRATEVALG KETDQSPTLS TSSILSSSVS 1560 VNVLEEEPLT LTGISQTDES MSTIESWVEI TPSQTVKFSE SSSAPIIEGS GEVEENKNKI 1620 FNMVTDLPQR DPTDTLSPLD MSKIMITNHH IYIPATIAPL DSKLPSPDAR PTTVWNSNST 1680 SEWVSDKSFE GRKKKENEDE EGAVNAAHQG EVRAATERSD HLLLTPELES SNVDASSDLA 1740 TWEGFILETT PTESEKEMAN STPVFRETIG VANVEAQPFE HSSSSHPRVQ EELTTLSGNP 1800 PSLFTDLGSG DASTGMELIT ASLFTLDLES ETKVKKELPS TPSPSVEISS SFEPTGLTPS 1860 TVLDIEIAGV MSQTSQKTLI SEISGKPTSQ SGVRDLYTGF PMGEDFSGDF SEYPTVSYPT 1920 MKEETVGMGG SDDERVRDTQ TSSSIPTTSD NIYPVPDSKG PDSTVASTTA FPWEEVMSSA 1980 EGSGEQLASV RSSVGPVLPL AVDIFSGTES PYFDEEFEEV AAVTEANERP TVLPTAASGN 2040 TVDLTENGYI EVNSTMSLDF PQTMEPSKLW SKPEVNLDKQ EIGRETVTKE KAQGQKTFES 2100 LHSSFAPEQT ILETQSLIET EFQTSDYSML TTLKTYITNK EVEEEGMSIA HMSTPGPGIK 2160 DLESYTTHPE APGKSHSFSA TALVTESGAA RSVLMDSSTQ EEESIKLFQK GVKLTNKESN 2220 ADLSFSGLGS GGALPPLPTT SVNLTDMKQI ISTLYAETSH MESLGTSILG DKMEDHERME 2280 DVSSNEVRML ISKIGSISQD STEALDTTLS HTGTEEPTTS TLPFVKLMDL ERSPKQDPSG 2340 GKRKPKTHRP QTMSGLISNE NSSASEAEEG ATSPTAFLPQ TYSVEMTKHF APSESQPSDL 2400 FNVNSGEGSG EVDTLDLVYT SGTTQASSQG DSMLASHGFL EKHPEVSKTE AGATDVSPTA 2460 SAMFLHHSEY KSSLYPTSTL PSTEPYKSPS EGIEDGLQDN IQFEGSTLKP SRRKTTESII 2520 IDLDKEDSKD LGLTITESAI VKSLPELTSD KNIIIDIDHT KPVYEYIPGI QTDLDPEIKL 2580 ESHGSSEESL QVQEKYEGAV TLSPTEESFE GSGDALLAGY TQAIYNESVT PNDGKQAEDI 2640 SFSFATGIPV SSTETELHTF FPTASTLHIP SKLTTASPEI DKPNIEAISL DDIFESSTLS 2700 DGQAIADQSE VISTLGHLEK TQEEYEEKKY GGPSFQPEFF SGVGEVLTDP PAYVSIGSTY 2760 LIAQTLTELP NVVRPSDSTH YTEATPEVSS LAELSPQIPS SPFPVYVDNG VSKFPEVPHT 2820 SAQPVSTVTS SQKSIESPFK EVHANIEETI KPLGGNVHRT EPPSMSRDPA LDVSEDESKH 2880 KLLEELETSP TKPETSQDFP NKAKDHIPGE TVGMLAGIRT TESEPVITAD DMELGGATQQ 2940 PHSASAAFRV ETGMVPQPIQ QEPERPTFPS LEINHETHTS LFGESILATS EKQVSQKILD 3000 NSNQATVSST LDLHTAHALS PFSILDNSNE TAFLIGISEE SVEGTAVYLP GPDLCKTNPC 3060 LNGGTCYPTE TSYVCTCAPG YSGDQCELDF DECHSNPCRN GATCVDGFNT FRCLCLPSYV 3120 GALCEQDTET CDYGWHKFQG QCYKYFAHRR TWDAAERECR LQGAHLTSIL SHEEQMFVNR 3180 VGHDYQWIGL NDKMFEHDFR WTDGSALQYE NWRPNQPDSF FSAGEDCVVI IWHENGQWND 3240 VPCNYHLTYT CKKGTVACGQ PPVVENAKTF GKMKPRYEIN SLIRYHCKDG FIQRHLPTIR 3300 CLGNGRWAMP KITCMNPSAY QRTYSKKYLK NSSSAKDNSI NTSKHEHRWS RRQETRR 3357 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.