| Tag | Content |
|---|---|
| Uniprot ID | Q8NAX2; Q5QP32; Q8N0S7; |
| Entrez ID | 126695 |
| Genbank protein ID | BAC03775.1; AAH33143.1; |
| Genbank nucleotide ID | XM_005245735.2; XM_011540622.1; NM_152365.2; |
| Ensembl protein ID | ENSP00000319179 |
| Ensembl nucleotide ID | ENSG00000175707 |
| Gene name | Keratinocyte differentiation factor 1 |
| Gene symbol | KDF1 |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity). |
| Sequence | MPRPGHPRPA SGPPRLGPWE RPTELCLETY DKPPQPPPSR RTRRPDPKDP GHHGPESITF 60 ISGSAEPALE SPTCCLLWRP WVWEWCRAAF CFRRCRDCLQ RCGACVRGCS PCLSTEDSTE 120 GTAEANWAKE HNGVPPSPDR APPSRRDGQR LKSTMGSSFS YPDVKLKGIP VYPYPRATSP 180 APDADSCCKE PLADPPPMRH SLPSTFASSP RGSEEYYSFH ESDLDLPEMG SGSMSSREID 240 VLIFKKLTEL FSVHQIDELA KCTSDTVFLE KTSKISDLIS SITQDYHLDE QDAEGRLVRG 300 IIRISTRKSR ARPQTSEGRS TRAAAPTAAA PDSGHETMVG SGLSQDELTV QISQETTADA 360 IARKLRPYGA PGYPASHDSS FQGTDTDSSG APLLQVYC 398 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.