| Tag | Content |
|---|---|
| Uniprot ID | Q92688; B2R9C7; O00655; P78458; P78459; |
| Entrez ID | 10541 |
| Genbank protein ID | CAA68855.1; EAW58865.1; BAG36474.1; AAH13003.1; CAA69265.1; AAB37579.1; CAA68856.1; AAH19658.1; |
| Genbank nucleotide ID | NM_006401.2 |
| Ensembl protein ID | ENSP00000345848 |
| Ensembl nucleotide ID | ENSG00000136938 |
| Gene name | Acidic leucine-rich nuclear phosphoprotein 32 family member B |
| Gene symbol | ANP32B |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome. |
| Sequence | MDMKRRIHLE LRNRTPAAVR ELVLDNCKSN DGKIEGLTAE FVNLEFLSLI NVGLISVSNL 60 PKLPKLKKLE LSENRIFGGL DMLAEKLPNL THLNLSGNKL KDISTLEPLK KLECLKSLDL 120 FNCEVTNLND YRESVFKLLP QLTYLDGYDR EDQEAPDSDA EVDGVDEEEE DEEGEDEEDE 180 DDEDGEEEEF DEEDDEDEDV EGDEDDDEVS EEEEEFGLDE EDEDEDEDEE EEEGGKGEKR 240 KRETDDEGED D 251 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.