CleftGeneDB-Search

Gene: KIF20B

Basic information

Tag	Content
Uniprot ID	Q96Q89; A8MXM7; O43277; Q09471; Q2KQ73; Q32NE1; Q561V3; Q58EX8; Q5T9M8; Q5T9M9; Q5T9N0; Q5T9N1; Q7KZ68; Q7Z5E0; Q7Z5E1; Q7Z6M9; Q86X82; Q9H3R8; Q9H6Q9; Q9H755; Q9NTC1; Q9UFR5;
Entrez ID	9585
Genbank protein ID	BAB15194.1; BAB20417.1; AAH46134.1; BAB15043.1; AAC37542.1; AAP40331.1; AAI08689.1; BAB69456.1; AAP40330.1; AAB88727.1; AAW65984.1; AAH93089.1; CAB70720.1; AAH58913.1; CAB55962.1;
Genbank nucleotide ID	NM_016195.3; NM_001284259.1;
Ensembl protein ID	ENSP00000260753; ENSP00000360793;
Ensembl nucleotide ID	ENSG00000138182
Gene name	Kinesin-like protein KIF20B
Gene symbol	KIF20B
Organism	Homo sapiens
NCBI taxa ID	9606
Cleft type
Developmental stage
Data sources	Homology search
Reference
Functional description	Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).
Sequence	MESNFNQEGV PRPSYVFSAD PIARPSEINF DGIKLDLSHE FSLVAPNTEA NSFESKDYLQ 60 VCLRIRPFTQ SEKELESEGC VHILDSQTVV LKEPQCILGR LSEKSSGQMA QKFSFSKVFG 120 PATTQKEFFQ GCIMQPVKDL LKGQSRLIFT YGLTNSGKTY TFQGTEENIG ILPRTLNVLF 180 DSLQERLYTK MNLKPHRSRE YLRLSSEQEK EEIASKSALL RQIKEVTVHN DSDDTLYGSL 240 TNSLNISEFE ESIKDYEQAN LNMANSIKFS VWVSFFEIYN EYIYDLFVPV SSKFQKRKML 300 RLSQDVKGYS FIKDLQWIQV SDSKEAYRLL KLGIKHQSVA FTKLNNASSR SHSIFTVKIL 360 QIEDSEMSRV IRVSELSLCD LAGSERTMKT QNEGERLRET GNINTSLLTL GKCINVLKNS 420 EKSKFQQHVP FRESKLTHYF QSFFNGKGKI CMIVNISQCY LAYDETLNVL KFSAIAQKVC 480 VPDTLNSSQE KLFGPVKSSQ DVSLDSNSNS KILNVKRATI SWENSLEDLM EDEDLVEELE 540 NAEETQNVET KLLDEDLDKT LEENKAFISH EEKRKLLDLI EDLKKKLINE KKEKLTLEFK 600 IREEVTQEFT QYWAQREADF KETLLQEREI LEENAERRLA IFKDLVGKCD TREEAAKDIC 660 ATKVETEETH NYVGFEDIID SLQDNVADIK KQAEIAHLYI ASLPDPQEAT ACLELKFNQI 720 KAELAKTKGE LIKTKEELKK RENESDSLIQ ELETSNKKII TQNQRIKELI NIIDQKEDTI 780 NEFQNLKSHM ENTFKCNDKA DTSSLIINNK LICNETVEVP KDSKSKICSE RKRVNENELQ 840 QDEPPAKKGS IHVSSAITED QKKSEEVRPN IAEIEDIRVL QENNEGLRAF LLTIENELKN 900 EKEEKAELNK QIVHFQQELS LSEKKNLTLS KEVQQIQSNY DIAIAELHVQ KSKNQEQEEK 960 IMKLSNEIET ATRSITNNVS QIKLMHTKID ELRTLDSVSQ ISNIDLLNLR DLSNGSEEDN 1020 LPNTQLDLLG NDYLVSKQVK EYRIQEPNRE NSFHSSIEAI WEECKEIVKA SSKKSHQIEE 1080 LEQQIEKLQA EVKGYKDENN RLKEKEHKNQ DDLLKEKETL IQQLKEELQE KNVTLDVQIQ 1140 HVVEGKRALS ELTQGVTCYK AKIKELETIL ETQKVECSHS AKLEQDILEK ESIILKLERN 1200 LKEFQEHLQD SVKNTKDLNV KELKLKEEIT QLTNNLQDMK HLLQLKEEEE ETNRQETEKL 1260 KEELSASSAR TQNLKADLQR KEEDYADLKE KLTDAKKQIK QVQKEVSVMR DEDKLLRIKI 1320 NELEKKKNQC SQELDMKQRT IQQLKEQLNN QKVEEAIQQY ERACKDLNVK EKIIEDMRMT 1380 LEEQEQTQVE QDQVLEAKLE EVERLATELE KWKEKCNDLE TKNNQRSNKE HENNTDVLGK 1440 LTNLQDELQE SEQKYNADRK KWLEEKMMLI TQAKEAENIR NKEMKKYAED RERFFKQQNE 1500 MEILTAQLTE KDSDLQKWRE ERDQLVAALE IQLKALISSN VQKDNEIEQL KRIISETSKI 1560 ETQIMDIKPK RISSADPDKL QTEPLSTSFE ISRNKIEDGS VVLDSCEVST ENDQSTRFPK 1620 PELEIQFTPL QPNKMAVKHP GCTTPVTVKI PKARKRKSNE MEEDLVKCEN KKNATPRTNL 1680 KFPISDDRNS SVKKEQKVAI RPSSKKTYSL RSQASIIGVN LATKKKEGTL QKFGDFLQHS 1740 PSILQSKAKK IIETMSSSKL SNVEASKENV SQPKRAKRKL YTSEISSPID ISGQVILMDQ 1800 KMKESDHQII KRRLRTKTAK

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Relation	Gene symbol	Entrez ID	UniProt ID	Cleft type	Species	Evidence	Details
1:1 ortholog	KIF20B		A0A452EC51		Capra hircus	Prediction	More>>
1:1 ortholog	KIF20B	9585	Q96Q89		Homo sapiens	Prediction	More>>
1:1 ortholog	Kif20b	240641	Q80WE4	CPO	Mus musculus	Publication	More>>
1:1 ortholog	KIF20B	450592	H2R321		Pan troglodytes	Prediction	More>>
1:1 ortholog		100155885	A0A480ZX77		Sus scrofa	Prediction	More>>
1:1 ortholog	KIF20B	100339334	G1SHM7		Oryctolagus cuniculus	Prediction	More>>
1:1 ortholog	Kif20b	309523	D3ZX13		Rattus norvegicus	Prediction	More>>

Other genetic variants/mutations

ID	Variant	Type	Disease	Chromosome\Coordinate	Evidence
rs371111411	p.Glu2Asp	missense variant	-	NC_000010.11:g.89705300A>C	ESP,TOPMed
NCI-TCGA novel	p.Glu2Lys	missense variant	-	NC_000010.11:g.89705298G>A	NCI-TCGA
NCI-TCGA novel	p.Ser3Cys	missense variant	-	NC_000010.11:g.89705302C>G	NCI-TCGA
rs768060728	p.Asn6Asp	missense variant	-	NC_000010.11:g.89705310A>G	ExAC,TOPMed,gnomAD
rs776275732	p.Gln7Lys	missense variant	-	NC_000010.11:g.89705313C>A	ExAC,gnomAD
rs1401157152	p.Gly9Glu	missense variant	-	NC_000010.11:g.89705320G>A	TOPMed
rs531008769	p.Pro11Ser	missense variant	-	NC_000010.11:g.89705325C>T	gnomAD
rs761585032	p.Arg12Gln	missense variant	-	NC_000010.11:g.89705329G>A	ExAC,TOPMed,gnomAD
rs761585032	p.Arg12Gln	missense variant	-	NC_000010.11:g.89705329G>A	NCI-TCGA,NCI-TCGA Cosmic
rs114316057	p.Tyr15Ter	stop gained	-	NC_000010.11:g.89705339T>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1437025874	p.Tyr15His	missense variant	-	NC_000010.11:g.89705337T>C	TOPMed
NCI-TCGA novel	p.Tyr15Asp	missense variant	-	NC_000010.11:g.89705337T>G	NCI-TCGA
NCI-TCGA novel	p.Val16Gly	missense variant	-	NC_000010.11:g.89705341T>G	NCI-TCGA
rs1167628361	p.Phe17Ser	missense variant	-	NC_000010.11:g.89705344T>C	TOPMed
rs774900148	p.Ala19Val	missense variant	-	NC_000010.11:g.89705350C>T	ExAC,gnomAD
rs1335039056	p.Asp20Val	missense variant	-	NC_000010.11:g.89705353A>T	gnomAD
rs1360995928	p.Ile22Asn	missense variant	-	NC_000010.11:g.89705359T>A	gnomAD
COSM3441422	p.Ile22Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89705360T>G	NCI-TCGA Cosmic
rs143432523	p.Ala23Ser	missense variant	-	NC_000010.11:g.89705361G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs143432523	p.Ala23Thr	missense variant	-	NC_000010.11:g.89705361G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Arg24Gly	missense variant	-	NC_000010.11:g.89705364A>G	NCI-TCGA
NCI-TCGA novel	p.Glu27Ter	stop gained	-	NC_000010.11:g.89705373G>T	NCI-TCGA
rs753159710	p.Glu27Asp	missense variant	-	NC_000010.11:g.89705375A>T	ExAC,gnomAD
rs370731821	p.Asp31His	missense variant	-	NC_000010.11:g.89705385G>C	ESP,ExAC,TOPMed,gnomAD
rs1194896120	p.Asp31Gly	missense variant	-	NC_000010.11:g.89705386A>G	gnomAD
rs370731821	p.Asp31Asn	missense variant	-	NC_000010.11:g.89705385G>A	ESP,ExAC,TOPMed,gnomAD
rs757522974	p.Ile33Val	missense variant	-	NC_000010.11:g.89705391A>G	ExAC,gnomAD
rs374375791	p.Lys34Asn	missense variant	-	NC_000010.11:g.89705396G>C	ESP
rs764984414	p.Asp36Gly	missense variant	-	NC_000010.11:g.89705401A>G	ExAC,gnomAD
rs1443767282	p.Asp36Tyr	missense variant	-	NC_000010.11:g.89705400G>T	gnomAD
rs148065279	p.His39Arg	missense variant	-	NC_000010.11:g.89705410A>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.His39Gln	missense variant	-	NC_000010.11:g.89705411T>G	NCI-TCGA
rs779980736	p.Glu40Lys	missense variant	-	NC_000010.11:g.89705412G>A	ExAC,gnomAD
rs879431020	p.Ser42Cys	missense variant	-	NC_000010.11:g.89705419C>G	TOPMed
COSM1968821	p.Ser42Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89705419C>T	NCI-TCGA Cosmic
rs1475266085	p.Ser42Ala	missense variant	-	NC_000010.11:g.89705418T>G	gnomAD
rs368331856	p.Val44Phe	missense variant	-	NC_000010.11:g.89705424G>T	ESP,ExAC,TOPMed,gnomAD
rs1427592434	p.Ala45Thr	missense variant	-	NC_000010.11:g.89705427G>A	gnomAD
rs780902590	p.Pro46Ser	missense variant	-	NC_000010.11:g.89705430C>T	ExAC,gnomAD
rs780902590	p.Pro46Ser	missense variant	-	NC_000010.11:g.89705430C>T	NCI-TCGA
rs1129777	p.Ala50Gly	missense variant	-	NC_000010.11:g.89709168C>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1129777	p.Ala50Gly	missense variant	-	NC_000010.11:g.89709168C>G	UniProt,dbSNP
VAR_030181	p.Ala50Gly	missense variant	-	NC_000010.11:g.89709168C>G	UniProt
rs1381027300	p.Ala50Ser	missense variant	-	NC_000010.11:g.89709167G>T	gnomAD
rs1056194785	p.Asn51Ser	missense variant	-	NC_000010.11:g.89709171A>G	TOPMed
rs1156898393	p.Asn51Tyr	missense variant	-	NC_000010.11:g.89709170A>T	gnomAD
rs1156898393	p.Asn51Asp	missense variant	-	NC_000010.11:g.89709170A>G	gnomAD
rs778521871	p.Phe53Leu	missense variant	-	NC_000010.11:g.89709178C>A	TOPMed,gnomAD
rs1323971498	p.Glu54Lys	missense variant	-	NC_000010.11:g.89709179G>A	gnomAD
rs947679379	p.Glu54Val	missense variant	-	NC_000010.11:g.89709180A>T	-
rs1323971498	p.Glu54Lys	missense variant	-	NC_000010.11:g.89709179G>A	NCI-TCGA Cosmic
rs947679379	p.Glu54Val	missense variant	-	NC_000010.11:g.89709180A>T	NCI-TCGA Cosmic
rs1332545576	p.Ser55Cys	missense variant	-	NC_000010.11:g.89709183C>G	gnomAD
rs758141800	p.Lys56Glu	missense variant	-	NC_000010.11:g.89709185A>G	ExAC,gnomAD
COSM921299	p.Lys56Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89709187A>C	NCI-TCGA Cosmic
rs766114784	p.Asp57Gly	missense variant	-	NC_000010.11:g.89709189A>G	ExAC,TOPMed
rs367726513	p.Tyr58His	missense variant	-	NC_000010.11:g.89709191T>C	ESP,ExAC,TOPMed,gnomAD
rs1160673754	p.Leu59Arg	missense variant	-	NC_000010.11:g.89709195T>G	gnomAD
rs375851858	p.Gln60Pro	missense variant	-	NC_000010.11:g.89709198A>C	ESP,ExAC,TOPMed,gnomAD
rs201280490	p.Arg64Gln	missense variant	-	NC_000010.11:g.89709210G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs201280490	p.Arg64Gln	missense variant	-	NC_000010.11:g.89709210G>A	NCI-TCGA
rs1283252329	p.Pro67Ala	missense variant	-	NC_000010.11:g.89709218C>G	gnomAD
rs747721266	p.Glu72Gln	missense variant	-	NC_000010.11:g.89709233G>C	ExAC,gnomAD
COSM5476965	p.Glu74Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89709239G>T	NCI-TCGA Cosmic
rs755701011	p.Leu75Pro	missense variant	-	NC_000010.11:g.89709243T>C	ExAC,gnomAD
rs777502341	p.Glu76Lys	missense variant	-	NC_000010.11:g.89709245G>A	ExAC,gnomAD
rs140554027	p.Ser77Pro	missense variant	-	NC_000010.11:g.89709248T>C	ESP,ExAC,TOPMed,gnomAD
rs1279975424	p.Gly79Asp	missense variant	-	NC_000010.11:g.89709346G>A	TOPMed,gnomAD
rs755646052	p.Cys80Tyr	missense variant	-	NC_000010.11:g.89709349G>A	ExAC,gnomAD
NCI-TCGA novel	p.Val81Ala	missense variant	-	NC_000010.11:g.89709352T>C	NCI-TCGA
rs369439648	p.His82Arg	missense variant	-	NC_000010.11:g.89709355A>G	ESP,TOPMed,gnomAD
rs1395185860	p.His82Asp	missense variant	-	NC_000010.11:g.89709354C>G	gnomAD
rs369439648	p.His82Pro	missense variant	-	NC_000010.11:g.89709355A>C	ESP,TOPMed,gnomAD
rs1314221873	p.Gln87His	missense variant	-	NC_000010.11:g.89709371G>C	TOPMed,gnomAD
rs1279246917	p.Val89Ile	missense variant	-	NC_000010.11:g.89709375G>A	gnomAD
rs758962805	p.Leu91Val	missense variant	-	NC_000010.11:g.89709381C>G	TOPMed,gnomAD
rs201328071	p.Leu91Pro	missense variant	-	NC_000010.11:g.89709382T>C	ExAC,TOPMed,gnomAD
rs756898969	p.Lys92Arg	missense variant	-	NC_000010.11:g.89709385A>G	ExAC,gnomAD
rs200362702	p.Glu93Gly	missense variant	-	NC_000010.11:g.89709388A>G	ExAC,TOPMed,gnomAD
rs1484655439	p.Gln95Ter	stop gained	-	NC_000010.11:g.89709393C>T	gnomAD
rs1484655439	p.Gln95Ter	stop gained	-	NC_000010.11:g.89709393C>T	NCI-TCGA Cosmic
rs748681486	p.Cys96Arg	missense variant	-	NC_000010.11:g.89709396T>C	ExAC,TOPMed,gnomAD
rs199632456	p.Ile97Val	missense variant	-	NC_000010.11:g.89709399A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs773209778	p.Arg100Trp	missense variant	-	NC_000010.11:g.89709408C>T	ExAC,TOPMed,gnomAD
rs773209778	p.Arg100Trp	missense variant	-	NC_000010.11:g.89709408C>T	NCI-TCGA,NCI-TCGA Cosmic
rs763235804	p.Arg100Leu	missense variant	-	NC_000010.11:g.89709409G>T	ExAC,gnomAD
NCI-TCGA novel	p.Arg100Gln	missense variant	-	NC_000010.11:g.89709409G>A	NCI-TCGA
rs1018194599	p.Ser102Gly	missense variant	-	NC_000010.11:g.89709414A>G	TOPMed,gnomAD
rs1018194599	p.Ser102Arg	missense variant	-	NC_000010.11:g.89709414A>C	TOPMed,gnomAD
rs774649782	p.Ser105Gly	missense variant	-	NC_000010.11:g.89709423A>G	ExAC,gnomAD
rs1299300012	p.Ser105Asn	missense variant	-	NC_000010.11:g.89709424G>A	gnomAD
rs1213226504	p.Ser106Pro	missense variant	-	NC_000010.11:g.89709426T>C	gnomAD
rs759189061	p.Ser106Leu	missense variant	-	NC_000010.11:g.89709427C>T	ExAC,TOPMed,gnomAD
rs1436625710	p.Gly107Val	missense variant	-	NC_000010.11:g.89709430G>T	gnomAD
rs1313070240	p.Met109Thr	missense variant	-	NC_000010.11:g.89709436T>C	gnomAD
rs767453897	p.Ala110Thr	missense variant	-	NC_000010.11:g.89709438G>A	ExAC,gnomAD
rs752634082	p.Gln111Lys	missense variant	-	NC_000010.11:g.89709441C>A	ExAC,gnomAD
COSM921302	p.Lys112Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89709444A>C	NCI-TCGA Cosmic
rs1210117148	p.Phe115Leu	missense variant	-	NC_000010.11:g.89709453T>C	gnomAD
rs376346565	p.Ser116Phe	missense variant	-	NC_000010.11:g.89709457C>T	ESP,ExAC,gnomAD
rs376346565	p.Ser116Tyr	missense variant	-	NC_000010.11:g.89709457C>A	ESP,ExAC,gnomAD
rs756920160	p.Lys117Thr	missense variant	-	NC_000010.11:g.89709460A>C	ExAC,gnomAD
rs1038163377	p.Lys117Glu	missense variant	-	NC_000010.11:g.89709459A>G	TOPMed,gnomAD
rs1038163377	p.Lys117Gln	missense variant	-	NC_000010.11:g.89709459A>C	TOPMed,gnomAD
rs756920160	p.Lys117Arg	missense variant	-	NC_000010.11:g.89709460A>G	ExAC,gnomAD
COSM921303	p.Gly120Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89709934G>A	NCI-TCGA Cosmic
rs372714100	p.Pro121Ser	missense variant	-	NC_000010.11:g.89709936C>T	ESP,ExAC,TOPMed,gnomAD
rs140764762	p.Ala122Gly	missense variant	-	NC_000010.11:g.89709940C>G	ESP,ExAC,TOPMed,gnomAD
rs541129006	p.Thr123Ser	missense variant	-	NC_000010.11:g.89709942A>T	1000Genomes,ExAC,gnomAD
rs541129006	p.Thr123Ala	missense variant	-	NC_000010.11:g.89709942A>G	1000Genomes,ExAC,gnomAD
rs771970019	p.Gln125Arg	missense variant	-	NC_000010.11:g.89709949A>G	ExAC,gnomAD
rs1182948308	p.Lys126Glu	missense variant	-	NC_000010.11:g.89709951A>G	TOPMed
rs149777607	p.Ile133Val	missense variant	-	NC_000010.11:g.89709972A>G	ESP,ExAC,TOPMed,gnomAD
rs374626048	p.Met134Val	missense variant	-	NC_000010.11:g.89709975A>G	ESP,ExAC,TOPMed,gnomAD
rs769714206	p.Gln135His	missense variant	-	NC_000010.11:g.89709980A>C	ExAC,TOPMed,gnomAD
rs116079640	p.Lys138Arg	missense variant	-	NC_000010.11:g.89709988A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs764831714	p.Leu140Phe	missense variant	-	NC_000010.11:g.89709993C>T	ExAC
rs749990301	p.Leu140Pro	missense variant	-	NC_000010.11:g.89709994T>C	ExAC,gnomAD
rs758091272	p.Leu141Ter	stop gained	-	NC_000010.11:g.89709997T>A	ExAC,gnomAD
NCI-TCGA novel	p.Leu141Phe	missense variant	-	NC_000010.11:g.89709998G>T	NCI-TCGA
rs767867106	p.Lys142Glu	missense variant	-	NC_000010.11:g.89709999A>G	ExAC,gnomAD
rs190543605	p.Gln144Arg	missense variant	-	NC_000010.11:g.89710006A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs1447791865	p.Gln144His	missense variant	-	NC_000010.11:g.89710007G>C	gnomAD
rs778078682	p.Ser145Asn	missense variant	-	NC_000010.11:g.89710009G>A	ExAC,gnomAD
rs773327403	p.Arg146His	missense variant	-	NC_000010.11:g.89710012G>A	TOPMed,gnomAD
rs368664005	p.Arg146Cys	missense variant	-	NC_000010.11:g.89710011C>T	ESP,ExAC,TOPMed,gnomAD
rs368664005	p.Arg146Cys	missense variant	-	NC_000010.11:g.89710011C>T	NCI-TCGA,NCI-TCGA Cosmic
rs942538562	p.Phe149Ser	missense variant	-	NC_000010.11:g.89710021T>C	TOPMed
rs1168636776	p.Thr150Ala	missense variant	-	NC_000010.11:g.89710023A>G	TOPMed
rs376662889	p.Tyr151Ter	stop gained	-	NC_000010.11:g.89710028C>G	ExAC,TOPMed,gnomAD
rs372770283	p.Gly152Arg	missense variant	-	NC_000010.11:g.89710029G>A	ESP,ExAC,TOPMed,gnomAD
COSM921305	p.Gly152Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89710030G>A	NCI-TCGA Cosmic
rs372770283	p.Gly152Arg	missense variant	-	NC_000010.11:g.89710029G>C	ESP,ExAC,TOPMed,gnomAD
rs903288308	p.Thr154Ser	missense variant	-	NC_000010.11:g.89710036C>G	gnomAD
rs746740786	p.Asn155His	missense variant	-	NC_000010.11:g.89710038A>C	ExAC,gnomAD
COSM921306	p.Lys158Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89710048A>C	NCI-TCGA Cosmic
NCI-TCGA novel	p.Thr159HisPheSerTerUnkUnk	frameshift	-	NC_000010.11:g.89710046A>-	NCI-TCGA
rs1415218716	p.Tyr160Cys	missense variant	-	NC_000010.11:g.89710054A>G	gnomAD
rs776389826	p.Thr161Ile	missense variant	-	NC_000010.11:g.89710057C>T	ExAC,gnomAD
rs200906639	p.Phe162Leu	missense variant	-	NC_000010.11:g.89710059T>C	1000Genomes
rs1400441533	p.Gly164Glu	missense variant	-	NC_000010.11:g.89710961G>A	gnomAD
rs1213559245	p.Gly170Asp	missense variant	-	NC_000010.11:g.89710979G>A	gnomAD
rs948773833	p.Pro173Leu	missense variant	-	NC_000010.11:g.89710988C>T	TOPMed,gnomAD
rs948773833	p.Pro173Arg	missense variant	-	NC_000010.11:g.89710988C>G	TOPMed,gnomAD
rs770462070	p.Arg174Gln	missense variant	-	NC_000010.11:g.89710991G>A	ExAC,TOPMed
rs770462070	p.Arg174Gln	missense variant	-	NC_000010.11:g.89710991G>A	NCI-TCGA,NCI-TCGA Cosmic
rs200997811	p.Arg174Ter	stop gained	-	NC_000010.11:g.89710990C>T	ExAC,TOPMed,gnomAD
rs1208057468	p.Asn177Ser	missense variant	-	NC_000010.11:g.89711000A>G	gnomAD
NCI-TCGA novel	p.Asn177Asp	missense variant	-	NC_000010.11:g.89710999A>G	NCI-TCGA
NCI-TCGA novel	p.Asn177Ile	missense variant	-	NC_000010.11:g.89711000A>T	NCI-TCGA
rs759285059	p.Phe180Leu	missense variant	-	NC_000010.11:g.89711008T>C	ExAC,gnomAD
rs1164042783	p.Asp181Ala	missense variant	-	NC_000010.11:g.89711012A>C	TOPMed
rs1195856719	p.Leu183Pro	missense variant	-	NC_000010.11:g.89711018T>C	gnomAD
rs1240652767	p.Gln184Pro	missense variant	-	NC_000010.11:g.89711021A>C	gnomAD
NCI-TCGA novel	p.Glu185Lys	missense variant	-	NC_000010.11:g.89711023G>A	NCI-TCGA
rs1397005058	p.Leu187Pro	missense variant	-	NC_000010.11:g.89711030T>C	gnomAD
rs1422014586	p.Tyr188Cys	missense variant	-	NC_000010.11:g.89711033A>G	TOPMed
rs764335006	p.Thr189Ala	missense variant	-	NC_000010.11:g.89711035A>G	ExAC,gnomAD
rs1374837078	p.Lys194Glu	missense variant	-	NC_000010.11:g.89711050A>G	gnomAD
rs1320050810	p.His196Arg	missense variant	-	NC_000010.11:g.89711057A>G	TOPMed,gnomAD
rs1320050810	p.His196Leu	missense variant	-	NC_000010.11:g.89711057A>T	TOPMed,gnomAD
rs376008434	p.Arg197Ser	missense variant	-	NC_000010.11:g.89711061A>T	ESP,TOPMed
NCI-TCGA novel	p.Arg197Lys	missense variant	-	NC_000010.11:g.89711060G>A	NCI-TCGA
rs148503567	p.Tyr201His	missense variant	-	NC_000010.11:g.89711071T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Tyr201Asn	missense variant	-	NC_000010.11:g.89711071T>A	NCI-TCGA
rs758511172	p.Leu202Ser	missense variant	-	NC_000010.11:g.89711075T>C	ExAC,gnomAD
rs1231515805	p.Leu202Phe	missense variant	-	NC_000010.11:g.89711076A>C	gnomAD
rs1048057	p.Arg203Trp	missense variant	-	NC_000010.11:g.89711077A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1292979738	p.Ser205Leu	missense variant	-	NC_000010.11:g.89711084C>T	TOPMed,gnomAD
rs1327770259	p.Ser206Ter	stop gained	-	NC_000010.11:g.89711087C>A	gnomAD
rs1207349056	p.Ser206Ala	missense variant	-	NC_000010.11:g.89711086T>G	TOPMed,gnomAD
rs1207349056	p.Ser206Pro	missense variant	-	NC_000010.11:g.89711086T>C	TOPMed,gnomAD
NCI-TCGA novel	p.Glu209Gln	missense variant	-	NC_000010.11:g.89711095G>C	NCI-TCGA
rs755264224	p.Lys210Arg	missense variant	-	NC_000010.11:g.89711099A>G	ExAC,gnomAD
COSM921307	p.Glu211Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89711101G>T	NCI-TCGA Cosmic
rs780841689	p.Ala214Thr	missense variant	-	NC_000010.11:g.89711110G>A	ExAC,gnomAD
rs199753491	p.Ser215Asn	missense variant	-	NC_000010.11:g.89711114G>A	ESP,ExAC,TOPMed,gnomAD
rs1255185936	p.Ser215Gly	missense variant	-	NC_000010.11:g.89711113A>G	gnomAD
rs534581065	p.Lys216Arg	missense variant	-	NC_000010.11:g.89711117A>G	1000Genomes,ExAC,gnomAD
rs749248822	p.Ser217Asn	missense variant	-	NC_000010.11:g.89711120G>A	ExAC,TOPMed,gnomAD
rs1382653346	p.Leu220Val	missense variant	-	NC_000010.11:g.89711128C>G	TOPMed,gnomAD
rs369964051	p.Arg221Trp	missense variant	-	NC_000010.11:g.89711131C>T	ESP,ExAC,TOPMed,gnomAD
rs1326317707	p.Arg221Gln	missense variant	-	NC_000010.11:g.89711132G>A	gnomAD
rs759107250	p.Gln222Arg	missense variant	-	NC_000010.11:g.89711135A>G	ExAC,gnomAD
rs1009129144	p.Ile223Val	missense variant	-	NC_000010.11:g.89711137A>G	gnomAD
rs775018455	p.Ile223Thr	missense variant	-	NC_000010.11:g.89711138T>C	ExAC,gnomAD
rs775018455	p.Ile223Asn	missense variant	-	NC_000010.11:g.89711138T>A	ExAC,gnomAD
rs770921849	p.Val228Gly	missense variant	-	NC_000010.11:g.89714054T>G	ExAC,gnomAD
rs778382667	p.His229Leu	missense variant	-	NC_000010.11:g.89714057A>T	ExAC,TOPMed,gnomAD
rs778382667	p.His229Arg	missense variant	-	NC_000010.11:g.89714057A>G	ExAC,TOPMed,gnomAD
rs1333089782	p.His229Asp	missense variant	-	NC_000010.11:g.89714056C>G	gnomAD
rs771486548	p.Asn230Ser	missense variant	-	NC_000010.11:g.89714060A>G	ExAC,gnomAD
rs775166996	p.Asp231Gly	missense variant	-	NC_000010.11:g.89714063A>G	ExAC,gnomAD
rs201672657	p.Ser232Cys	missense variant	-	NC_000010.11:g.89714065A>T	ExAC,TOPMed,gnomAD
rs770258775	p.Thr235Ile	missense variant	-	NC_000010.11:g.89714075C>T	ExAC,TOPMed,gnomAD
rs964891843	p.Ser239Cys	missense variant	-	NC_000010.11:g.89714957A>T	TOPMed
rs367738722	p.Ser239Asn	missense variant	-	NC_000010.11:g.89714958G>A	ESP,ExAC,TOPMed,gnomAD
rs964891843	p.Ser239Gly	missense variant	-	NC_000010.11:g.89714957A>G	TOPMed
rs367738722	p.Ser239Ile	missense variant	-	NC_000010.11:g.89714958G>T	ESP,ExAC,TOPMed,gnomAD
rs760876341	p.Asn242Lys	missense variant	-	NC_000010.11:g.89714968C>G	ExAC,gnomAD
rs1261121084	p.Ser243Pro	missense variant	-	NC_000010.11:g.89714969T>C	gnomAD
rs764245271	p.Leu244Phe	missense variant	-	NC_000010.11:g.89714974G>C	ExAC,TOPMed,gnomAD
rs1218020735	p.Leu244Ser	missense variant	-	NC_000010.11:g.89714973T>C	TOPMed
rs754063164	p.Asn245Thr	missense variant	-	NC_000010.11:g.89714976A>C	ExAC,TOPMed,gnomAD
rs1277782575	p.Phe249Cys	missense variant	-	NC_000010.11:g.89714988T>G	TOPMed
rs1454442018	p.Glu250Gly	missense variant	-	NC_000010.11:g.89714991A>G	TOPMed,gnomAD
rs764963927	p.Glu250Asp	missense variant	-	NC_000010.11:g.89714992A>C	ExAC
rs750351064	p.Glu251Gly	missense variant	-	NC_000010.11:g.89714994A>G	ExAC,gnomAD
rs182944047	p.Glu251Lys	missense variant	-	NC_000010.11:g.89714993G>A	1000Genomes
rs1342476150	p.Ser252Pro	missense variant	-	NC_000010.11:g.89714996T>C	TOPMed
rs964294773	p.Ile253Val	missense variant	-	NC_000010.11:g.89714999A>G	TOPMed
rs375843991	p.Ile253Met	missense variant	-	NC_000010.11:g.89715001A>G	ESP,ExAC,TOPMed,gnomAD
rs188045870	p.Asp255Gly	missense variant	-	NC_000010.11:g.89715006A>G	1000Genomes,ExAC,gnomAD
rs1288643331	p.Gln258Glu	missense variant	-	NC_000010.11:g.89715014C>G	gnomAD
rs1395581811	p.Ala259Val	missense variant	-	NC_000010.11:g.89715018C>T	gnomAD
rs1414798721	p.Asn260Tyr	missense variant	-	NC_000010.11:g.89715020A>T	TOPMed
rs1399140161	p.Asn260Ser	missense variant	-	NC_000010.11:g.89715021A>G	TOPMed
rs754547001	p.Asn260Lys	missense variant	-	NC_000010.11:g.89715022C>A	ExAC,gnomAD
NCI-TCGA novel	p.Leu261Phe	missense variant	-	NC_000010.11:g.89715025G>T	NCI-TCGA
rs747827642	p.Asn262Ser	missense variant	-	NC_000010.11:g.89715027A>G	ExAC,gnomAD
rs1315428577	p.Asn265Ser	missense variant	-	NC_000010.11:g.89715036A>G	gnomAD
rs377632658	p.Ile267Val	missense variant	-	NC_000010.11:g.89715041A>G	ESP,ExAC,TOPMed,gnomAD
rs779189217	p.Lys268Arg	missense variant	-	NC_000010.11:g.89715045A>G	ExAC,gnomAD
NCI-TCGA novel	p.Lys268Thr	missense variant	-	NC_000010.11:g.89715045A>C	NCI-TCGA
NCI-TCGA novel	p.Lys268Asn	missense variant	-	NC_000010.11:g.89715046A>T	NCI-TCGA
rs746383366	p.Val271Leu	missense variant	-	NC_000010.11:g.89715053G>C	ExAC,TOPMed,gnomAD
rs746383366	p.Val271Met	missense variant	-	NC_000010.11:g.89715053G>A	ExAC,TOPMed,gnomAD
COSM3807947	p.Phe275Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89715067C>G	NCI-TCGA Cosmic
rs776079423	p.Phe275Tyr	missense variant	-	NC_000010.11:g.89715066T>A	ExAC,TOPMed,gnomAD
rs776079423	p.Phe275Ser	missense variant	-	NC_000010.11:g.89715066T>C	ExAC,TOPMed,gnomAD
rs201019984	p.Phe276Val	missense variant	-	NC_000010.11:g.89715068T>G	ESP,ExAC,TOPMed,gnomAD
rs768752700	p.Tyr279Cys	missense variant	-	NC_000010.11:g.89715078A>G	ExAC,gnomAD
rs776785358	p.Asn280Ser	missense variant	-	NC_000010.11:g.89715081A>G	ExAC,TOPMed,gnomAD
rs1467670043	p.Ile283Phe	missense variant	-	NC_000010.11:g.89715089A>T	gnomAD
rs200892725	p.Tyr284Ter	stop gained	-	NC_000010.11:g.89715094T>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs765046922	p.Tyr284Cys	missense variant	-	NC_000010.11:g.89715093A>G	ExAC,TOPMed,gnomAD
rs766167617	p.Val288Ile	missense variant	-	NC_000010.11:g.89715104G>A	ExAC,gnomAD
NCI-TCGA novel	p.Val288Ala	missense variant	-	NC_000010.11:g.89715105T>C	NCI-TCGA
rs754491953	p.Lys293Glu	missense variant	-	NC_000010.11:g.89715119A>G	ExAC,gnomAD
rs1324093442	p.Gln295Arg	missense variant	-	NC_000010.11:g.89715126A>G	TOPMed,gnomAD
rs1393985414	p.Lys296Gln	missense variant	-	NC_000010.11:g.89715128A>C	gnomAD
COSM4915728	p.Lys298Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89715135A>G	NCI-TCGA Cosmic
rs1443088696	p.Met299Leu	missense variant	-	NC_000010.11:g.89715137A>T	TOPMed,gnomAD
rs1443088696	p.Met299Val	missense variant	-	NC_000010.11:g.89715137A>G	TOPMed,gnomAD
rs755790468	p.Arg301His	missense variant	-	NC_000010.11:g.89715144G>A	ExAC,TOPMed,gnomAD
rs138800578	p.Arg301Cys	missense variant	-	NC_000010.11:g.89715143C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs755790468	p.Arg301Leu	missense variant	-	NC_000010.11:g.89715144G>T	ExAC,TOPMed,gnomAD
COSM3441426	p.Ser303Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89715150C>T	NCI-TCGA Cosmic
rs372546647	p.Val306Leu	missense variant	-	NC_000010.11:g.89715158G>T	ESP,ExAC,TOPMed,gnomAD
rs372546647	p.Val306Ile	missense variant	-	NC_000010.11:g.89715158G>A	ESP,ExAC,TOPMed,gnomAD
rs1234871077	p.Lys307Arg	missense variant	-	NC_000010.11:g.89715162A>G	gnomAD
rs375586078	p.Tyr309Cys	missense variant	-	NC_000010.11:g.89715168A>G	ESP,ExAC,TOPMed,gnomAD
rs1163530893	p.Ile312Val	missense variant	-	NC_000010.11:g.89715176A>G	TOPMed
rs758639872	p.Asp314Val	missense variant	-	NC_000010.11:g.89716436A>T	ExAC
rs1475875082	p.Asp314Glu	missense variant	-	NC_000010.11:g.89716437T>A	gnomAD
COSM466065	p.Leu315Pro	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89716439T>C	NCI-TCGA Cosmic
NCI-TCGA novel	p.Leu315Val	missense variant	-	NC_000010.11:g.89716438C>G	NCI-TCGA
rs1317197078	p.Gln316Arg	missense variant	-	NC_000010.11:g.89716442A>G	TOPMed
rs967139129	p.Gln316Ter	stop gained	-	NC_000010.11:g.89716441C>T	TOPMed,gnomAD
rs1174324802	p.Trp317Cys	missense variant	-	NC_000010.11:g.89716446G>T	gnomAD
NCI-TCGA novel	p.Trp317Cys	missense variant	-	NC_000010.11:g.89716446G>C	NCI-TCGA
rs747481872	p.Ile318Ser	missense variant	-	NC_000010.11:g.89716448T>G	ExAC,gnomAD
rs1305381289	p.Gln319Ter	stop gained	-	NC_000010.11:g.89716450C>T	gnomAD
rs755542197	p.Ser323Cys	missense variant	-	NC_000010.11:g.89716463C>G	ExAC,gnomAD
NCI-TCGA novel	p.Ser323Phe	missense variant	-	NC_000010.11:g.89716463C>T	NCI-TCGA
rs781231658	p.Glu325Lys	missense variant	-	NC_000010.11:g.89716468G>A	ExAC,gnomAD
rs1431052490	p.Tyr327Cys	missense variant	-	NC_000010.11:g.89716475A>G	gnomAD
rs1331651224	p.Tyr327Ter	stop gained	-	NC_000010.11:g.89716476T>A	gnomAD
COSM921308	p.Arg328Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89716478G>T	NCI-TCGA Cosmic
rs1346863495	p.Arg328Lys	missense variant	-	NC_000010.11:g.89716478G>A	TOPMed
rs748115970	p.Arg328Gly	missense variant	-	NC_000010.11:g.89716477A>G	ExAC,TOPMed,gnomAD
rs769919021	p.Leu329Pro	missense variant	-	NC_000010.11:g.89716481T>C	ExAC,gnomAD
COSM6067294	p.Ile334Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89716497A>G	NCI-TCGA Cosmic
rs1406165606	p.His336Gln	missense variant	-	NC_000010.11:g.89716503C>A	TOPMed
rs367763475	p.Ser338Asn	missense variant	-	NC_000010.11:g.89716508G>A	ESP,ExAC,TOPMed,gnomAD
rs1455639607	p.Lys343Asn	missense variant	-	NC_000010.11:g.89716524A>T	TOPMed
rs767505076	p.Asn346Lys	missense variant	-	NC_000010.11:g.89716533T>A	ExAC,TOPMed,gnomAD
rs377232644	p.Ser348Cys	missense variant	-	NC_000010.11:g.89716538C>G	ESP,ExAC,TOPMed,gnomAD
rs1194343108	p.Ser349Asn	missense variant	-	NC_000010.11:g.89716541G>A	gnomAD
rs760064623	p.Ser351Thr	missense variant	-	NC_000010.11:g.89716547G>C	ExAC,TOPMed,gnomAD
rs573176470	p.His352Arg	missense variant	-	NC_000010.11:g.89717426A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs573176470	p.His352Pro	missense variant	-	NC_000010.11:g.89717426A>C	1000Genomes,ExAC,TOPMed,gnomAD
rs760714022	p.Ser353Thr	missense variant	-	NC_000010.11:g.89717429G>C	ExAC,TOPMed,gnomAD
rs760714022	p.Ser353Asn	missense variant	-	NC_000010.11:g.89717429G>A	ExAC,TOPMed,gnomAD
rs763478746	p.Ile354Val	missense variant	-	NC_000010.11:g.89717431A>G	ExAC,TOPMed,gnomAD
rs776271223	p.Thr356Ala	missense variant	-	NC_000010.11:g.89717437A>G	ExAC,gnomAD
rs1293745676	p.Lys358Arg	missense variant	-	NC_000010.11:g.89717444A>G	TOPMed
rs1222003535	p.Leu360Ter	stop gained	-	NC_000010.11:g.89717450T>G	TOPMed
rs1316012058	p.Gln361Arg	missense variant	-	NC_000010.11:g.89717453A>G	TOPMed
rs764809501	p.Gln361His	missense variant	-	NC_000010.11:g.89717454G>C	ExAC,gnomAD
NCI-TCGA novel	p.Gln361AspPheSerTerUnk	frameshift	-	NC_000010.11:g.89717451_89717452AC>-	NCI-TCGA
rs1281742674	p.Asp364Ala	missense variant	-	NC_000010.11:g.89717462A>C	TOPMed
rs1275337093	p.Asp364Asn	missense variant	-	NC_000010.11:g.89717461G>A	gnomAD
NCI-TCGA novel	p.Glu366Lys	missense variant	-	NC_000010.11:g.89717467G>A	NCI-TCGA
rs555767778	p.Ser368Phe	missense variant	-	NC_000010.11:g.89717474C>T	ExAC,TOPMed,gnomAD
rs1438344995	p.Ser368Ala	missense variant	-	NC_000010.11:g.89717473T>G	gnomAD
rs555767778	p.Ser368Cys	missense variant	-	NC_000010.11:g.89717474C>G	ExAC,TOPMed,gnomAD
rs150890799	p.Arg369His	missense variant	-	NC_000010.11:g.89717477G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs767920353	p.Arg369Cys	missense variant	-	NC_000010.11:g.89717476C>T	ExAC,TOPMed,gnomAD
COSM3441428	p.Ile371Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89717483T>C	NCI-TCGA Cosmic
rs371676289	p.Arg372Ter	stop gained	-	NC_000010.11:g.89717485C>T	ESP,TOPMed,gnomAD
rs756715290	p.Arg372Gln	missense variant	-	NC_000010.11:g.89717486G>A	ExAC,TOPMed,gnomAD
rs777705827	p.Val373Phe	missense variant	-	NC_000010.11:g.89717488G>T	ExAC
rs1412877109	p.Ser374Thr	missense variant	-	NC_000010.11:g.89717492G>C	TOPMed
rs1162142113	p.Glu375Lys	missense variant	-	NC_000010.11:g.89717494G>A	gnomAD
rs140162687	p.Ser377Thr	missense variant	-	NC_000010.11:g.89717580T>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1427783864	p.Cys379Ser	missense variant	-	NC_000010.11:g.89717586T>A	TOPMed
rs1465110570	p.Ala382Val	missense variant	-	NC_000010.11:g.89717596C>T	TOPMed
rs1188037095	p.Ala382Thr	missense variant	-	NC_000010.11:g.89717595G>A	TOPMed
rs1400457473	p.Glu385Lys	missense variant	-	NC_000010.11:g.89717604G>A	gnomAD
rs767771862	p.Arg386Gln	missense variant	-	NC_000010.11:g.89717608G>A	ExAC,TOPMed,gnomAD
rs762636055	p.Arg386Ter	stop gained	-	NC_000010.11:g.89717607C>T	ExAC,TOPMed,gnomAD
rs753166649	p.Thr387Ser	missense variant	-	NC_000010.11:g.89717611C>G	ExAC,gnomAD
rs1462275798	p.Met388Thr	missense variant	-	NC_000010.11:g.89717614T>C	TOPMed
rs150319905	p.Lys389Asn	missense variant	-	NC_000010.11:g.89717618G>T	1000Genomes,ESP,TOPMed,gnomAD
rs1307413444	p.Thr390Ala	missense variant	-	NC_000010.11:g.89717619A>G	TOPMed
rs1226361268	p.Thr390Ile	missense variant	-	NC_000010.11:g.89717620C>T	gnomAD
rs1296883429	p.Glu393Val	missense variant	-	NC_000010.11:g.89717629A>T	gnomAD
rs760964846	p.Gly394Asp	missense variant	-	NC_000010.11:g.89717632G>A	ExAC,gnomAD
rs1341383895	p.Gly394Arg	missense variant	-	NC_000010.11:g.89717631G>C	gnomAD
rs1341383895	p.Gly394Ser	missense variant	-	NC_000010.11:g.89717631G>A	gnomAD
rs1282240827	p.Arg396Lys	missense variant	-	NC_000010.11:g.89717638G>A	gnomAD
rs374218650	p.Leu397Ile	missense variant	-	NC_000010.11:g.89717640T>A	1000Genomes,ExAC,gnomAD
rs754334159	p.Glu399Lys	missense variant	-	NC_000010.11:g.89717646G>A	ExAC,gnomAD
rs1429927407	p.Thr400Ala	missense variant	-	NC_000010.11:g.89717649A>G	gnomAD
NCI-TCGA novel	p.Thr400Ile	missense variant	-	NC_000010.11:g.89717650C>T	NCI-TCGA
rs1186131810	p.Asn402Ser	missense variant	-	NC_000010.11:g.89717656A>G	gnomAD
rs1455105434	p.Asn404Ile	missense variant	-	NC_000010.11:g.89717662A>T	gnomAD
rs372350190	p.Asn404Tyr	missense variant	-	NC_000010.11:g.89717661A>T	ESP,ExAC,TOPMed
rs1465903356	p.Ser406Cys	missense variant	-	NC_000010.11:g.89717668C>G	gnomAD
rs758759265	p.Cys413Tyr	missense variant	-	NC_000010.11:g.89717689G>A	ExAC,gnomAD
rs1366329188	p.Cys413Arg	missense variant	-	NC_000010.11:g.89717688T>C	TOPMed
rs149456198	p.Val416Ile	missense variant	-	NC_000010.11:g.89717697G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs149456198	p.Val416Ile	missense variant	-	NC_000010.11:g.89717697G>A	NCI-TCGA
rs1310356821	p.Leu417Phe	missense variant	-	NC_000010.11:g.89717702G>T	gnomAD
rs139360783	p.Ser420Gly	missense variant	-	NC_000010.11:g.89717709A>G	1000Genomes,ESP,ExAC,gnomAD
rs548202480	p.Ser420Asn	missense variant	-	NC_000010.11:g.89717710G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs1246918973	p.Lys422Glu	missense variant	-	NC_000010.11:g.89717715A>G	gnomAD
rs1303499097	p.Ser423Ala	missense variant	-	NC_000010.11:g.89717718T>G	TOPMed
rs369009574	p.Lys424Arg	missense variant	-	NC_000010.11:g.89717722A>G	ESP,ExAC,TOPMed,gnomAD
rs769265565	p.Lys424Glu	missense variant	-	NC_000010.11:g.89717721A>G	ExAC,gnomAD
rs1287410937	p.Gln426Ter	stop gained	-	NC_000010.11:g.89718714C>T	gnomAD
rs1272917739	p.Gln427His	missense variant	-	NC_000010.11:g.89718719G>C	TOPMed
rs770380331	p.His428Asp	missense variant	-	NC_000010.11:g.89718720C>G	ExAC,gnomAD
rs946529893	p.Val429Met	missense variant	-	NC_000010.11:g.89718723G>A	TOPMed
rs769035292	p.Arg432Gln	missense variant	-	NC_000010.11:g.89718733G>A	ExAC,TOPMed,gnomAD
rs745557342	p.Arg432Trp	missense variant	-	NC_000010.11:g.89718732C>T	ExAC,TOPMed,gnomAD
rs777201675	p.Glu433Gly	missense variant	-	NC_000010.11:g.89718736A>G	ExAC,gnomAD
rs1381375117	p.Ser434Gly	missense variant	-	NC_000010.11:g.89718738A>G	TOPMed
rs369346911	p.His438Arg	missense variant	-	NC_000010.11:g.89718751A>G	ESP,ExAC,TOPMed,gnomAD
rs765780636	p.His438Tyr	missense variant	-	NC_000010.11:g.89718750C>T	ExAC
rs553169925	p.Tyr439Cys	missense variant	-	NC_000010.11:g.89718754A>G	1000Genomes,ExAC,gnomAD
rs143205873	p.Gln441His	missense variant	-	NC_000010.11:g.89718761A>T	ESP,ExAC,TOPMed,gnomAD
COSM4695992	p.Phe444LeuPheSerTerUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89718764T>-	NCI-TCGA Cosmic
rs755224380	p.Asn445Asp	missense variant	-	NC_000010.11:g.89718771A>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asn445Ter	frameshift	-	NC_000010.11:g.89718763_89718764insT	NCI-TCGA
rs940553981	p.Ile450Leu	missense variant	-	NC_000010.11:g.89718786A>C	TOPMed
NCI-TCGA novel	p.Ile450Val	missense variant	-	NC_000010.11:g.89718786A>G	NCI-TCGA
rs1372331213	p.Cys451Tyr	missense variant	-	NC_000010.11:g.89718790G>A	TOPMed,gnomAD
NCI-TCGA novel	p.Ile453Thr	missense variant	-	NC_000010.11:g.89718796T>C	NCI-TCGA
rs1307205397	p.Asn455Ser	missense variant	-	NC_000010.11:g.89718802A>G	gnomAD
NCI-TCGA novel	p.Ile456Val	missense variant	-	NC_000010.11:g.89718804A>G	NCI-TCGA
NCI-TCGA novel	p.Tyr460Cys	missense variant	-	NC_000010.11:g.89718817A>G	NCI-TCGA
rs770205047	p.Tyr463Cys	missense variant	-	NC_000010.11:g.89718826A>G	ExAC,gnomAD
rs1377972859	p.Asp464Asn	missense variant	-	NC_000010.11:g.89718828G>A	gnomAD
rs1050271409	p.Thr466Ile	missense variant	-	NC_000010.11:g.89718835C>T	TOPMed,gnomAD
rs1340679367	p.Asn468Ser	missense variant	-	NC_000010.11:g.89718841A>G	gnomAD
rs756771073	p.Val469Ala	missense variant	-	NC_000010.11:g.89718844T>C	ExAC,gnomAD
rs377662650	p.Ser473Pro	missense variant	-	NC_000010.11:g.89718855T>C	ESP,TOPMed
rs1050818241	p.Ala474Thr	missense variant	-	NC_000010.11:g.89718858G>A	TOPMed,gnomAD
rs371014201	p.Ile475Val	missense variant	-	NC_000010.11:g.89718861A>G	ESP,ExAC,TOPMed,gnomAD
rs1237184251	p.Ala476Val	missense variant	-	NC_000010.11:g.89718865C>T	gnomAD
rs1486276465	p.Gln477Arg	missense variant	-	NC_000010.11:g.89718868A>G	TOPMed,gnomAD
rs141485845	p.Cys480Ser	missense variant	-	NC_000010.11:g.89719423G>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs141485845	p.Cys480Tyr	missense variant	-	NC_000010.11:g.89719423G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
COSM921309	p.Cys480Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89719422T>C	NCI-TCGA Cosmic
rs778469833	p.Pro482Arg	missense variant	-	NC_000010.11:g.89719429C>G	ExAC,TOPMed,gnomAD
rs778469833	p.Pro482Gln	missense variant	-	NC_000010.11:g.89719429C>A	ExAC,TOPMed,gnomAD
rs371696680	p.Asp483Tyr	missense variant	-	NC_000010.11:g.89719431G>T	ESP,ExAC,TOPMed,gnomAD
rs147397224	p.Thr484Ser	missense variant	-	NC_000010.11:g.89719435C>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Thr484Ser	missense variant	-	NC_000010.11:g.89719434A>T	NCI-TCGA
rs1056602407	p.Asn486His	missense variant	-	NC_000010.11:g.89719440A>C	TOPMed
rs375018458	p.Ser488Phe	missense variant	-	NC_000010.11:g.89719447C>T	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ser488Cys	missense variant	-	NC_000010.11:g.89719447C>G	NCI-TCGA
rs17484219	p.Glu490Asp	missense variant	-	NC_000010.11:g.89719454G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs17484219	p.Glu490Asp	missense variant	-	NC_000010.11:g.89719454G>T	UniProt,dbSNP
VAR_030182	p.Glu490Asp	missense variant	-	NC_000010.11:g.89719454G>T	UniProt
rs1230598592	p.Phe493Ser	missense variant	-	NC_000010.11:g.89719462T>C	gnomAD
COSM6067292	p.Gly494Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89719465G>T	NCI-TCGA Cosmic
NCI-TCGA novel	p.Val496Ala	missense variant	-	NC_000010.11:g.89719471T>C	NCI-TCGA
rs548120859	p.Lys497Arg	missense variant	-	NC_000010.11:g.89719474A>G	ExAC,TOPMed,gnomAD
rs548120859	p.Lys497Ile	missense variant	-	NC_000010.11:g.89719474A>T	ExAC,TOPMed,gnomAD
rs1291468732	p.Ser498Pro	missense variant	-	NC_000010.11:g.89719476T>C	TOPMed
rs757053340	p.Gln500Glu	missense variant	-	NC_000010.11:g.89719482C>G	ExAC,TOPMed,gnomAD
rs1214403238	p.Asp501Tyr	missense variant	-	NC_000010.11:g.89719485G>T	gnomAD
rs1327823453	p.Val502Ile	missense variant	-	NC_000010.11:g.89719488G>A	TOPMed
rs1227033333	p.Asp505His	missense variant	-	NC_000010.11:g.89719497G>C	TOPMed
COSM921310	p.Asp505Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89719497G>T	NCI-TCGA Cosmic
rs958119693	p.Ser506Gly	missense variant	-	NC_000010.11:g.89719500A>G	TOPMed,gnomAD
rs775671805	p.Ser506Thr	missense variant	-	NC_000010.11:g.89719501G>C	ExAC,TOPMed,gnomAD
rs775671805	p.Ser506Asn	missense variant	-	NC_000010.11:g.89719501G>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ser506Ter	frameshift	-	NC_000010.11:g.89719500_89719501AG>-	NCI-TCGA
rs141486158	p.Asn509Lys	missense variant	-	NC_000010.11:g.89719511C>G	ESP,ExAC,TOPMed,gnomAD
rs150845034	p.Lys511Glu	missense variant	-	NC_000010.11:g.89719515A>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys511Asn	missense variant	-	NC_000010.11:g.89719517A>C	NCI-TCGA
rs765013645	p.Asn514Ser	missense variant	-	NC_000010.11:g.89719525A>G	ExAC,TOPMed,gnomAD
rs761678395	p.Asn514His	missense variant	-	NC_000010.11:g.89719524A>C	ExAC,TOPMed,gnomAD
rs761678395	p.Asn514Asp	missense variant	-	NC_000010.11:g.89719524A>G	ExAC,TOPMed,gnomAD
rs115052864	p.Lys516Arg	missense variant	-	NC_000010.11:g.89719531A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1444964039	p.Ala518Val	missense variant	-	NC_000010.11:g.89719537C>T	gnomAD
rs1323535396	p.Ile520Thr	missense variant	-	NC_000010.11:g.89719543T>C	gnomAD
rs757932251	p.Ile520Val	missense variant	-	NC_000010.11:g.89719542A>G	ExAC,gnomAD
NCI-TCGA novel	p.Ile520Leu	missense variant	-	NC_000010.11:g.89719542A>C	NCI-TCGA
rs751225494	p.Trp522Cys	missense variant	-	NC_000010.11:g.89719550G>T	ExAC,gnomAD
rs1286775074	p.Asn524Asp	missense variant	-	NC_000010.11:g.89719554A>G	gnomAD
rs780913616	p.Ser525Asn	missense variant	-	NC_000010.11:g.89719558G>A	ExAC,TOPMed,gnomAD
rs535352183	p.Leu526Pro	missense variant	-	NC_000010.11:g.89719561T>C	1000Genomes,ExAC,gnomAD
rs535352183	p.Leu526Arg	missense variant	-	NC_000010.11:g.89719561T>G	1000Genomes,ExAC,gnomAD
NCI-TCGA novel	p.Glu527Ter	stop gained	-	NC_000010.11:g.89719563G>T	NCI-TCGA
rs746427013	p.Met530Ile	missense variant	-	NC_000010.11:g.89719574G>A	ExAC,TOPMed,gnomAD
rs779240069	p.Met530Leu	missense variant	-	NC_000010.11:g.89719572A>T	ExAC,TOPMed,gnomAD
rs1483341788	p.Asp532Tyr	missense variant	-	NC_000010.11:g.89719578G>T	gnomAD
rs775616820	p.Glu533Lys	missense variant	-	NC_000010.11:g.89719581G>A	ExAC,gnomAD
rs747221522	p.Glu538Gln	missense variant	-	NC_000010.11:g.89719596G>C	ExAC,gnomAD
rs776914048	p.Ala542Thr	missense variant	-	NC_000010.11:g.89719608G>A	ExAC,gnomAD
COSM921311	p.Glu544Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89719614G>A	NCI-TCGA Cosmic
rs1407671391	p.Thr545Ile	missense variant	-	NC_000010.11:g.89719618C>T	gnomAD
NCI-TCGA novel	p.Gln546Ter	stop gained	-	NC_000010.11:g.89719620C>T	NCI-TCGA
rs761472099	p.Asn547Ile	missense variant	-	NC_000010.11:g.89719624A>T	ExAC,gnomAD
rs765098083	p.Val548Glu	missense variant	-	NC_000010.11:g.89719627T>A	ExAC,gnomAD
rs765098083	p.Val548Ala	missense variant	-	NC_000010.11:g.89719627T>C	ExAC,gnomAD
rs773001312	p.Thr550Ser	missense variant	-	NC_000010.11:g.89719633C>G	ExAC,gnomAD
rs1219026345	p.Lys551Arg	missense variant	-	NC_000010.11:g.89719636A>G	TOPMed
rs146154520	p.Lys551Glu	missense variant	-	NC_000010.11:g.89719635A>G	ESP,ExAC,TOPMed,gnomAD
rs1276846309	p.Leu552Phe	missense variant	-	NC_000010.11:g.89719638C>T	TOPMed
rs140167608	p.Leu553Arg	missense variant	-	NC_000010.11:g.89719642T>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs140167608	p.Leu553Pro	missense variant	-	NC_000010.11:g.89719642T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1338918540	p.Asp554Glu	missense variant	-	NC_000010.11:g.89719646T>G	gnomAD
rs1244244914	p.Asp556Glu	missense variant	-	NC_000010.11:g.89719652T>A	gnomAD
rs373446473	p.Asp558Gly	missense variant	-	NC_000010.11:g.89719657A>G	ESP,ExAC,TOPMed,gnomAD
rs373446473	p.Asp558Val	missense variant	-	NC_000010.11:g.89719657A>T	ESP,ExAC,TOPMed,gnomAD
rs1364636200	p.Asp558Tyr	missense variant	-	NC_000010.11:g.89719656G>T	TOPMed
rs941361816	p.Lys559Glu	missense variant	-	NC_000010.11:g.89719659A>G	TOPMed
rs1175224001	p.Leu561Val	missense variant	-	NC_000010.11:g.89719665T>G	TOPMed
rs1200805646	p.Glu563Gly	missense variant	-	NC_000010.11:g.89719672A>G	TOPMed,gnomAD
rs1482633345	p.Glu563Lys	missense variant	-	NC_000010.11:g.89719671G>A	gnomAD
rs779378406	p.Asn564Ser	missense variant	-	NC_000010.11:g.89719675A>G	ExAC,gnomAD
rs1257918755	p.Asn564Asp	missense variant	-	NC_000010.11:g.89719674A>G	TOPMed,gnomAD
NCI-TCGA novel	p.Asn564Thr	missense variant	-	NC_000010.11:g.89719675A>C	NCI-TCGA
rs1186243011	p.Lys565Glu	missense variant	-	NC_000010.11:g.89719677A>G	gnomAD
rs746372007	p.Ala566Ser	missense variant	-	NC_000010.11:g.89719680G>T	ExAC,gnomAD
rs746372007	p.Ala566Pro	missense variant	-	NC_000010.11:g.89719680G>C	ExAC,gnomAD
rs377420072	p.Ser569Thr	missense variant	-	NC_000010.11:g.89719690G>C	ESP,ExAC,TOPMed,gnomAD
rs780550307	p.His570Tyr	missense variant	-	NC_000010.11:g.89719692C>T	ExAC,gnomAD
NCI-TCGA novel	p.Glu571Lys	missense variant	-	NC_000010.11:g.89719695G>A	NCI-TCGA
rs768808298	p.Arg574Thr	missense variant	-	NC_000010.11:g.89719705G>C	ExAC,TOPMed,gnomAD
rs768808298	p.Arg574Lys	missense variant	-	NC_000010.11:g.89719705G>A	ExAC,TOPMed,gnomAD
rs1395617105	p.Arg574Ser	missense variant	-	NC_000010.11:g.89719706A>T	gnomAD
rs754987089	p.Asp578Ala	missense variant	-	NC_000010.11:g.89723974A>C	ExAC,TOPMed,gnomAD
rs371134968	p.Ile580Val	missense variant	-	NC_000010.11:g.89723979A>G	ESP,ExAC,TOPMed,gnomAD
rs748313937	p.Ile580Met	missense variant	-	NC_000010.11:g.89723981A>G	ExAC,TOPMed,gnomAD
rs770111248	p.Asp582Asn	missense variant	-	NC_000010.11:g.89723985G>A	ExAC,gnomAD
rs778153285	p.Lys584Glu	missense variant	-	NC_000010.11:g.89723991A>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys585Asn	missense variant	-	NC_000010.11:g.89723996A>C	NCI-TCGA
rs770872298	p.Lys586Asn	missense variant	-	NC_000010.11:g.89723999A>C	ExAC,TOPMed,gnomAD
rs759563026	p.Leu587Arg	missense variant	-	NC_000010.11:g.89724001T>G	ExAC,TOPMed,gnomAD
rs1266919497	p.Asn589Ser	missense variant	-	NC_000010.11:g.89724007A>G	gnomAD
NCI-TCGA novel	p.Asn589His	missense variant	-	NC_000010.11:g.89724006A>C	NCI-TCGA
rs771482152	p.Glu590Gly	missense variant	-	NC_000010.11:g.89724010A>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Glu590Lys	missense variant	-	NC_000010.11:g.89724009G>A	NCI-TCGA
rs1265830960	p.Lys592Glu	missense variant	-	NC_000010.11:g.89724015A>G	gnomAD
NCI-TCGA novel	p.Lys592ArgPheSerTerUnk	frameshift	-	NC_000010.11:g.89724010A>-	NCI-TCGA
rs1432984208	p.Lys594Arg	missense variant	-	NC_000010.11:g.89724022A>G	gnomAD
rs1454271169	p.Lys594Glu	missense variant	-	NC_000010.11:g.89724021A>G	TOPMed
rs775126321	p.Leu595Phe	missense variant	-	NC_000010.11:g.89724026A>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Leu595Ile	missense variant	-	NC_000010.11:g.89724024T>A	NCI-TCGA
rs1481263293	p.Thr596Ser	missense variant	-	NC_000010.11:g.89724027A>T	TOPMed
rs753517112	p.Glu598Ter	stop gained	-	NC_000010.11:g.89724033G>T	ExAC,gnomAD
rs901445846	p.Lys600Arg	missense variant	-	NC_000010.11:g.89724040A>G	TOPMed
rs763251034	p.Lys600Glu	missense variant	-	NC_000010.11:g.89724039A>G	ExAC,gnomAD
rs766774900	p.Ile601Val	missense variant	-	NC_000010.11:g.89724042A>G	ExAC,gnomAD
rs571660825	p.Arg602Ter	stop gained	-	NC_000010.11:g.89724045C>T	TOPMed,gnomAD
rs1486480017	p.Gln611Ter	stop gained	-	NC_000010.11:g.89724072C>T	TOPMed
rs1305805927	p.Tyr612Cys	missense variant	-	NC_000010.11:g.89724076A>G	gnomAD
rs866470653	p.Ala614Thr	missense variant	-	NC_000010.11:g.89724081G>A	gnomAD
rs866470653	p.Ala614Ser	missense variant	-	NC_000010.11:g.89724081G>T	gnomAD
rs1264211249	p.Gln615His	missense variant	-	NC_000010.11:g.89724086A>T	TOPMed,gnomAD
rs752762024	p.Arg616Gln	missense variant	-	NC_000010.11:g.89724088G>A	ExAC,gnomAD
rs1027968562	p.Arg616Trp	missense variant	-	NC_000010.11:g.89724087C>T	TOPMed
rs1326094307	p.Glu617Lys	missense variant	-	NC_000010.11:g.89724090G>A	TOPMed
rs1284217141	p.Glu617Gly	missense variant	-	NC_000010.11:g.89724091A>G	TOPMed
rs371085455	p.Ala618Thr	missense variant	-	NC_000010.11:g.89724093G>A	ESP,ExAC,TOPMed,gnomAD
rs1297861852	p.Phe620Leu	missense variant	-	NC_000010.11:g.89724101T>A	TOPMed
rs778094059	p.Lys621Thr	missense variant	-	NC_000010.11:g.89724103A>C	ExAC,TOPMed,gnomAD
rs1382784773	p.Lys621Gln	missense variant	-	NC_000010.11:g.89724102A>C	TOPMed
NCI-TCGA novel	p.Lys621Met	missense variant	-	NC_000010.11:g.89724103A>T	NCI-TCGA
rs146858896	p.Glu622Ala	missense variant	-	NC_000010.11:g.89725022A>C	1000Genomes,ExAC,TOPMed,gnomAD
rs754111994	p.Glu622Gln	missense variant	-	NC_000010.11:g.89725021G>C	ExAC,TOPMed,gnomAD
rs985560925	p.Thr623Ser	missense variant	-	NC_000010.11:g.89725025C>G	TOPMed,gnomAD
rs911415682	p.Gln626Arg	missense variant	-	NC_000010.11:g.89725034A>G	TOPMed
rs941548577	p.Glu627Val	missense variant	-	NC_000010.11:g.89725037A>T	TOPMed,gnomAD
rs142589580	p.Arg628Ter	stop gained	-	NC_000010.11:g.89725039C>T	ESP,ExAC,TOPMed,gnomAD
rs758155614	p.Arg628Gln	missense variant	-	NC_000010.11:g.89725040G>A	ExAC,gnomAD
rs758155614	p.Arg628Pro	missense variant	-	NC_000010.11:g.89725040G>C	ExAC,gnomAD
rs779990837	p.Glu629Lys	missense variant	-	NC_000010.11:g.89725042G>A	ExAC,gnomAD
rs746346176	p.Glu629Gly	missense variant	-	NC_000010.11:g.89725043A>G	ExAC,TOPMed,gnomAD
rs768120334	p.Ile630Leu	missense variant	-	NC_000010.11:g.89725045A>C	ExAC,TOPMed,gnomAD
rs150954557	p.Ile630Met	missense variant	-	NC_000010.11:g.89725047A>G	ESP,ExAC,TOPMed,gnomAD
rs768120334	p.Ile630Val	missense variant	-	NC_000010.11:g.89725045A>G	ExAC,TOPMed,gnomAD
rs769377812	p.Asn634Thr	missense variant	-	NC_000010.11:g.89725058A>C	ExAC,TOPMed,gnomAD
rs1404824792	p.Glu636Gly	missense variant	-	NC_000010.11:g.89725064A>G	gnomAD
rs375544106	p.Arg637Cys	missense variant	-	NC_000010.11:g.89725066C>T	ESP,ExAC,TOPMed,gnomAD
rs1221270148	p.Arg637His	missense variant	-	NC_000010.11:g.89725067G>A	TOPMed,gnomAD
rs1363717002	p.Arg638His	missense variant	-	NC_000010.11:g.89725070G>A	gnomAD
rs755409283	p.Arg638Cys	missense variant	-	NC_000010.11:g.89725069C>T	ExAC,TOPMed,gnomAD
rs767823064	p.Leu639Val	missense variant	-	NC_000010.11:g.89725072T>G	ExAC,TOPMed,gnomAD
rs368955427	p.Ala640Thr	missense variant	-	NC_000010.11:g.89725075G>A	ESP,ExAC,TOPMed,gnomAD
rs140716229	p.Ile641Val	missense variant	-	NC_000010.11:g.89725078A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs764260171	p.Phe642Leu	missense variant	-	NC_000010.11:g.89725081T>C	ExAC,TOPMed,gnomAD
rs753914848	p.Lys643Arg	missense variant	-	NC_000010.11:g.89725085A>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys643Asn	missense variant	-	NC_000010.11:g.89725086G>T	NCI-TCGA
rs757420354	p.Asp644Gly	missense variant	-	NC_000010.11:g.89725088A>G	ExAC,TOPMed,gnomAD
rs1206034890	p.Asp644Asn	missense variant	-	NC_000010.11:g.89725087G>A	TOPMed
rs757420354	p.Asp644Val	missense variant	-	NC_000010.11:g.89725088A>T	ExAC,TOPMed,gnomAD
rs1206034890	p.Asp644Tyr	missense variant	-	NC_000010.11:g.89725087G>T	TOPMed
rs767767972	p.Gly647Arg	missense variant	-	NC_000010.11:g.89725096G>C	TOPMed
rs1210735142	p.Lys648Asn	missense variant	-	NC_000010.11:g.89725101A>T	gnomAD
rs372702796	p.Thr651Ala	missense variant	-	NC_000010.11:g.89725108A>G	ESP,ExAC,TOPMed,gnomAD
rs372702796	p.Thr651Pro	missense variant	-	NC_000010.11:g.89725108A>C	ESP,ExAC,TOPMed,gnomAD
rs746958313	p.Arg652Gln	missense variant	-	NC_000010.11:g.89725112G>A	ExAC,gnomAD
rs758186840	p.Arg652Ter	stop gained	-	NC_000010.11:g.89725111C>T	ExAC,TOPMed,gnomAD
rs111669804	p.Glu654Ala	missense variant	-	NC_000010.11:g.89725118A>C	ExAC,TOPMed,gnomAD
rs111669804	p.Glu654Gly	missense variant	-	NC_000010.11:g.89725118A>G	ExAC,TOPMed,gnomAD
rs1478894265	p.Glu654Lys	missense variant	-	NC_000010.11:g.89725117G>A	TOPMed,gnomAD
rs781120688	p.Ala655Thr	missense variant	-	NC_000010.11:g.89725120G>A	ExAC,gnomAD
rs145716217	p.Ala656Glu	missense variant	-	NC_000010.11:g.89725124C>A	ESP,ExAC,TOPMed,gnomAD
rs145716217	p.Ala656Val	missense variant	-	NC_000010.11:g.89725124C>T	ESP,ExAC,TOPMed,gnomAD
rs376644821	p.Ala656Thr	missense variant	-	NC_000010.11:g.89725123G>A	ESP,ExAC,gnomAD
rs145716217	p.Ala656Gly	missense variant	-	NC_000010.11:g.89725124C>G	ESP,ExAC,TOPMed,gnomAD
rs775779401	p.Cys660Arg	missense variant	-	NC_000010.11:g.89725135T>C	ExAC,gnomAD
COSM4016543	p.Cys660Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89725136G>T	NCI-TCGA Cosmic
rs761139450	p.Ala661Val	missense variant	-	NC_000010.11:g.89725139C>T	ExAC,gnomAD
rs1230430143	p.Lys663Glu	missense variant	-	NC_000010.11:g.89725144A>G	TOPMed,gnomAD
rs777312246	p.Val664Ala	missense variant	-	NC_000010.11:g.89725148T>C	ExAC,TOPMed,gnomAD
rs761932655	p.Glu665Gly	missense variant	-	NC_000010.11:g.89725151A>G	ExAC,gnomAD
rs1290510809	p.Glu667Asp	missense variant	-	NC_000010.11:g.89725158A>C	gnomAD
rs1308448981	p.Glu668Lys	missense variant	-	NC_000010.11:g.89726293G>A	gnomAD
rs1163531647	p.Thr669Ser	missense variant	-	NC_000010.11:g.89726296A>T	TOPMed,gnomAD
rs762447837	p.His670Tyr	missense variant	-	NC_000010.11:g.89726299C>T	ExAC,TOPMed
rs1432021348	p.His670Arg	missense variant	-	NC_000010.11:g.89726300A>G	TOPMed,gnomAD
rs1432021348	p.His670Leu	missense variant	-	NC_000010.11:g.89726300A>T	TOPMed,gnomAD
NCI-TCGA novel	p.Asn671Thr	missense variant	-	NC_000010.11:g.89726303A>C	NCI-TCGA
rs1364705356	p.Tyr672His	missense variant	-	NC_000010.11:g.89726305T>C	gnomAD
rs199671628	p.Tyr672Ter	stop gained	-	NC_000010.11:g.89726307T>G	1000Genomes,ExAC,TOPMed,gnomAD
rs1415106024	p.Gly674Glu	missense variant	-	NC_000010.11:g.89726312G>A	TOPMed
rs1166618034	p.Glu676Gln	missense variant	-	NC_000010.11:g.89726317G>C	TOPMed
rs763106606	p.Ile678Ser	missense variant	-	NC_000010.11:g.89726324T>G	ExAC,TOPMed,gnomAD
rs1451939041	p.Asp680Glu	missense variant	-	NC_000010.11:g.89726331T>G	gnomAD
rs1314304144	p.Ser681Cys	missense variant	-	NC_000010.11:g.89726333C>G	gnomAD
rs1314304144	p.Ser681Tyr	missense variant	-	NC_000010.11:g.89726333C>A	gnomAD
rs1238818412	p.Gln683His	missense variant	-	NC_000010.11:g.89726340A>T	TOPMed
rs139423559	p.Asp684Val	missense variant	-	NC_000010.11:g.89726342A>T	1000Genomes,ExAC,gnomAD
rs139423559	p.Asp684Gly	missense variant	-	NC_000010.11:g.89726342A>G	1000Genomes,ExAC,gnomAD
rs113908675	p.Asn685Ile	missense variant	-	NC_000010.11:g.89726345A>T	1000Genomes,ExAC,TOPMed,gnomAD
rs113908675	p.Asn685Ser	missense variant	-	NC_000010.11:g.89726345A>G	1000Genomes,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ala687Thr	missense variant	-	NC_000010.11:g.89726350G>A	NCI-TCGA
rs551492524	p.Ile689Phe	missense variant	-	NC_000010.11:g.89726356A>T	1000Genomes,ExAC,TOPMed,gnomAD
rs1344888406	p.Ile689Met	missense variant	-	NC_000010.11:g.89726358T>G	TOPMed
rs1182368644	p.Leu698Phe	missense variant	-	NC_000010.11:g.89726385A>T	gnomAD
rs777783770	p.Leu698Ser	missense variant	-	NC_000010.11:g.89726384T>C	ExAC,gnomAD
rs757008979	p.Tyr699Cys	missense variant	-	NC_000010.11:g.89726387A>G	gnomAD
rs768009282	p.Tyr699His	missense variant	-	NC_000010.11:g.89726386T>C	TOPMed,gnomAD
rs753225098	p.Ile700Val	missense variant	-	NC_000010.11:g.89726389A>G	ExAC,gnomAD
rs753225098	p.Ile700Leu	missense variant	-	NC_000010.11:g.89726389A>C	ExAC,gnomAD
rs191962962	p.Ser702Thr	missense variant	-	NC_000010.11:g.89726395T>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1466836347	p.Pro704Arg	missense variant	-	NC_000010.11:g.89726402C>G	gnomAD
rs745562196	p.Asp705Glu	missense variant	-	NC_000010.11:g.89726406C>G	ExAC,gnomAD
rs745562196	p.Asp705Glu	missense variant	-	NC_000010.11:g.89726406C>A	ExAC,gnomAD
rs1469419098	p.Pro706Arg	missense variant	-	NC_000010.11:g.89726408C>G	gnomAD
NCI-TCGA novel	p.Gln707ProPheSerTerUnkUnk	frameshift	-	NC_000010.11:g.89726405_89726406insC	NCI-TCGA
rs781730356	p.Ala709Asp	missense variant	-	NC_000010.11:g.89726417C>A	ExAC,gnomAD
rs748647932	p.Thr710Ala	missense variant	-	NC_000010.11:g.89726419A>G	ExAC,TOPMed,gnomAD
rs773773250	p.Cys712Gly	missense variant	-	NC_000010.11:g.89726425T>G	ExAC,gnomAD
rs1325664745	p.Leu713Ser	missense variant	-	NC_000010.11:g.89726429T>C	gnomAD
rs964470518	p.Glu714Lys	missense variant	-	NC_000010.11:g.89726431G>A	TOPMed
COSM921312	p.Glu714Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89726431G>T	NCI-TCGA Cosmic
rs771063788	p.Gln719His	missense variant	-	NC_000010.11:g.89726448A>C	ExAC,TOPMed,gnomAD
rs762899192	p.Gln719Arg	missense variant	-	NC_000010.11:g.89726447A>G	ExAC,gnomAD
rs774526818	p.Ile720Leu	missense variant	-	NC_000010.11:g.89726449A>C	ExAC,gnomAD
rs759823642	p.Thr727Asn	missense variant	-	NC_000010.11:g.89726471C>A	ExAC,gnomAD
rs1202547461	p.Thr727Ala	missense variant	-	NC_000010.11:g.89726470A>G	TOPMed,gnomAD
rs1203925009	p.Lys728Glu	missense variant	-	NC_000010.11:g.89726473A>G	gnomAD
rs1261580176	p.Gly729Ter	stop gained	-	NC_000010.11:g.89726476G>T	gnomAD
COSM275736	p.Glu730Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89726479G>A	NCI-TCGA Cosmic
rs183238428	p.Lys735Asn	missense variant	-	NC_000010.11:g.89726496A>T	1000Genomes,ExAC,TOPMed,gnomAD
rs1160055698	p.Lys739Asn	missense variant	-	NC_000010.11:g.89726508A>C	gnomAD
NCI-TCGA novel	p.Lys740Asn	missense variant	-	NC_000010.11:g.89726511G>T	NCI-TCGA
rs760527281	p.Arg741Gly	missense variant	-	NC_000010.11:g.89726512A>G	ExAC,gnomAD
COSM3807951	p.Glu742Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89726515G>T	NCI-TCGA Cosmic
rs763900980	p.Asn743Asp	missense variant	-	NC_000010.11:g.89726518A>G	ExAC,TOPMed,gnomAD
rs763900980	p.Asn743His	missense variant	-	NC_000010.11:g.89726518A>C	ExAC,TOPMed,gnomAD
rs776398093	p.Ser745Leu	missense variant	-	NC_000010.11:g.89727859C>T	ExAC,gnomAD
rs1305650443	p.Asp746Asn	missense variant	-	NC_000010.11:g.89727861G>A	gnomAD
rs775923499	p.Leu748Phe	missense variant	-	NC_000010.11:g.89727869G>C	TOPMed,gnomAD
rs1019348983	p.Gln750Glu	missense variant	-	NC_000010.11:g.89727873C>G	TOPMed
rs1299000723	p.Leu752Phe	missense variant	-	NC_000010.11:g.89727879C>T	gnomAD
rs1248846151	p.Leu752Pro	missense variant	-	NC_000010.11:g.89727880T>C	gnomAD
COSM1968912	p.Glu753Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89727882G>C	NCI-TCGA Cosmic
rs764824532	p.Glu753Lys	missense variant	-	NC_000010.11:g.89727882G>A	ExAC,gnomAD
rs749892495	p.Thr754Ala	missense variant	-	NC_000010.11:g.89727885A>G	ExAC,gnomAD
rs1206233983	p.Thr754Lys	missense variant	-	NC_000010.11:g.89727886C>A	gnomAD
rs12572012	p.Asn756Ile	missense variant	-	NC_000010.11:g.89727892A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs200422852	p.Asn756Asp	missense variant	-	NC_000010.11:g.89727891A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs1425590100	p.Lys757Asn	missense variant	-	NC_000010.11:g.89727896G>T	gnomAD
rs756411084	p.Lys757Arg	missense variant	-	NC_000010.11:g.89727895A>G	ExAC,gnomAD
rs904759468	p.Lys758Glu	missense variant	-	NC_000010.11:g.89729128A>G	TOPMed
rs1421948070	p.Lys758Asn	missense variant	-	NC_000010.11:g.89729130A>T	TOPMed,gnomAD
rs1169325644	p.Ile760Val	missense variant	-	NC_000010.11:g.89729134A>G	gnomAD
rs773312148	p.Thr761Ile	missense variant	-	NC_000010.11:g.89729138C>T	ExAC,gnomAD
rs769783936	p.Thr761Ala	missense variant	-	NC_000010.11:g.89729137A>G	ExAC,TOPMed,gnomAD
rs762501126	p.Arg765Lys	missense variant	-	NC_000010.11:g.89729150G>A	ExAC,TOPMed,gnomAD
rs762501126	p.Arg765Ile	missense variant	-	NC_000010.11:g.89729150G>T	ExAC,TOPMed,gnomAD
rs1242043653	p.Ile766Val	missense variant	-	NC_000010.11:g.89729152A>G	TOPMed
rs751139534	p.Lys767Glu	missense variant	-	NC_000010.11:g.89729155A>G	ExAC,gnomAD
COSM1675416	p.Glu768Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89729158G>T	NCI-TCGA Cosmic
rs767089419	p.Leu769Ser	missense variant	-	NC_000010.11:g.89729162T>C	ExAC,gnomAD
rs754166229	p.Ile770Val	missense variant	-	NC_000010.11:g.89729164A>G	ExAC,gnomAD
rs116288233	p.Asn771Asp	missense variant	-	NC_000010.11:g.89729167A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs3758387	p.Ile772Val	missense variant	-	NC_000010.11:g.89729170A>G	gnomAD
COSM6130877	p.Asp774Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89729176G>T	NCI-TCGA Cosmic
rs779346249	p.Lys776Gln	missense variant	-	NC_000010.11:g.89729182A>C	ExAC,gnomAD
NCI-TCGA novel	p.Glu777Ter	stop gained	-	NC_000010.11:g.89729185G>T	NCI-TCGA
rs147005975	p.Ile780Val	missense variant	-	NC_000010.11:g.89729194A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs147005975	p.Ile780Phe	missense variant	-	NC_000010.11:g.89729194A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs780243396	p.Ile780Thr	missense variant	-	NC_000010.11:g.89729195T>C	ExAC,TOPMed,gnomAD
rs1243722331	p.Asn781Ser	missense variant	-	NC_000010.11:g.89729198A>G	gnomAD
rs1296800715	p.Glu782Asp	missense variant	-	NC_000010.11:g.89729202A>T	TOPMed
rs373615206	p.Glu782Lys	missense variant	-	NC_000010.11:g.89729200G>A	ESP,TOPMed,gnomAD
NCI-TCGA novel	p.Glu782Ala	missense variant	-	NC_000010.11:g.89729201A>C	NCI-TCGA
rs768863280	p.Gln784Ter	stop gained	-	NC_000010.11:g.89729206C>T	ExAC,gnomAD
rs781271666	p.Gln784Arg	missense variant	-	NC_000010.11:g.89729207A>G	ExAC,gnomAD
rs747911223	p.Leu786Val	missense variant	-	NC_000010.11:g.89729212C>G	ExAC,gnomAD
rs769732448	p.Lys787Asn	missense variant	-	NC_000010.11:g.89729217G>T	ExAC,TOPMed,gnomAD
rs3758388	p.His789Leu	missense variant	-	NC_000010.11:g.89729222A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1320867650	p.His789Asp	missense variant	-	NC_000010.11:g.89729221C>G	gnomAD
rs76150148	p.Met790Val	missense variant	-	NC_000010.11:g.89729224A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs909819762	p.Met790Ile	missense variant	-	NC_000010.11:g.89729226G>A	TOPMed
rs976720001	p.Glu791Lys	missense variant	-	NC_000010.11:g.89729227G>A	TOPMed
rs1394768783	p.Asn792Ile	missense variant	-	NC_000010.11:g.89729231A>T	TOPMed,gnomAD
rs1221951095	p.Cys796Ser	missense variant	-	NC_000010.11:g.89729242T>A	TOPMed,gnomAD
rs377501846	p.Asn797Lys	missense variant	-	NC_000010.11:g.89729247T>G	ESP,ExAC,gnomAD
rs528777679	p.Asn797Tyr	missense variant	-	NC_000010.11:g.89729245A>T	1000Genomes,ExAC,gnomAD
rs1329952739	p.Asn797Ser	missense variant	-	NC_000010.11:g.89729246A>G	gnomAD
rs1380062662	p.Asp798Gly	missense variant	-	NC_000010.11:g.89732904A>G	TOPMed
rs765569384	p.Asp798Glu	missense variant	-	NC_000010.11:g.89732905C>A	ExAC,gnomAD
rs1033738666	p.Asp801Gly	missense variant	-	NC_000010.11:g.89732913A>G	TOPMed
rs773503670	p.Thr802Ile	missense variant	-	NC_000010.11:g.89732916C>T	ExAC,gnomAD
rs1482266620	p.Thr802Ser	missense variant	-	NC_000010.11:g.89732915A>T	TOPMed,gnomAD
COSM3807953	p.Ser804Cys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89732922C>G	NCI-TCGA Cosmic
rs560443579	p.Ile806Val	missense variant	-	NC_000010.11:g.89732927A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs766866013	p.Ile806Arg	missense variant	-	NC_000010.11:g.89732928T>G	ExAC,TOPMed
rs752027575	p.Ile807Leu	missense variant	-	NC_000010.11:g.89732930A>C	ExAC,TOPMed,gnomAD
rs752027575	p.Ile807Val	missense variant	-	NC_000010.11:g.89732930A>G	ExAC,TOPMed,gnomAD
rs189443463	p.Asn808Lys	missense variant	-	NC_000010.11:g.89732935C>A	1000Genomes,TOPMed,gnomAD
NCI-TCGA novel	p.Asn808Lys	missense variant	-	NC_000010.11:g.89732935C>G	NCI-TCGA
rs1249941374	p.Leu811Trp	missense variant	-	NC_000010.11:g.89732943T>G	TOPMed
rs767533013	p.Asn814Ser	missense variant	-	NC_000010.11:g.89732952A>G	ExAC,gnomAD
rs1179678295	p.Glu815Ter	stop gained	-	NC_000010.11:g.89732954G>T	gnomAD
rs756348312	p.Pro820Ser	missense variant	-	NC_000010.11:g.89732969C>T	ExAC,gnomAD
rs1460807823	p.Ser823Arg	missense variant	-	NC_000010.11:g.89732980C>G	TOPMed
COSM921314	p.Ser823Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89732979G>A	NCI-TCGA Cosmic
rs1339702482	p.Ser823Gly	missense variant	-	NC_000010.11:g.89732978A>G	gnomAD
NCI-TCGA novel	p.Ser823Ile	missense variant	-	NC_000010.11:g.89732979G>T	NCI-TCGA
rs1253925115	p.Lys824Glu	missense variant	-	NC_000010.11:g.89732981A>G	TOPMed
rs757027479	p.Lys824Arg	missense variant	-	NC_000010.11:g.89732982A>G	ExAC,gnomAD
NCI-TCGA novel	p.Lys824Asn	missense variant	-	NC_000010.11:g.89732983A>C	NCI-TCGA
NCI-TCGA novel	p.Lys824Thr	missense variant	-	NC_000010.11:g.89732982A>C	NCI-TCGA
rs1201966012	p.Ser825Thr	missense variant	-	NC_000010.11:g.89732984T>A	TOPMed
rs778890662	p.Lys826Glu	missense variant	-	NC_000010.11:g.89732987A>G	ExAC,TOPMed,gnomAD
rs376723750	p.Cys828Ser	missense variant	-	NC_000010.11:g.89732994G>C	ESP,ExAC,TOPMed,gnomAD
rs144738424	p.Ser829Ter	stop gained	-	NC_000010.11:g.89732997C>G	ESP,ExAC,TOPMed
rs1297694740	p.Glu830Ala	missense variant	-	NC_000010.11:g.89733000A>C	TOPMed
NCI-TCGA novel	p.Arg831SerPheSerTerUnk	frameshift	-	NC_000010.11:g.89733003_89733004insCTAC	NCI-TCGA
rs148101512	p.Asn835Ser	missense variant	-	NC_000010.11:g.89733015A>G	ESP
rs989688519	p.Gln840Arg	missense variant	-	NC_000010.11:g.89733030A>G	TOPMed,gnomAD
rs371603977	p.Asp842Gly	missense variant	-	NC_000010.11:g.89733036A>G	ESP,ExAC,TOPMed,gnomAD
rs1374026137	p.Glu843Lys	missense variant	-	NC_000010.11:g.89733038G>A	gnomAD
rs374027434	p.Pro845Leu	missense variant	-	NC_000010.11:g.89733045C>T	ESP,ExAC,TOPMed,gnomAD
rs1403329599	p.Lys847Glu	missense variant	-	NC_000010.11:g.89733050A>G	TOPMed
rs1395957162	p.Lys848Asn	missense variant	-	NC_000010.11:g.89733055A>C	gnomAD
rs768226883	p.Lys848Thr	missense variant	-	NC_000010.11:g.89733054A>C	ExAC,gnomAD
rs1304584605	p.Gly849Glu	missense variant	-	NC_000010.11:g.89737387G>A	gnomAD
rs764311635	p.Ile851Val	missense variant	-	NC_000010.11:g.89737392A>G	ExAC,TOPMed,gnomAD
rs748246289	p.Ile851Thr	missense variant	-	NC_000010.11:g.89737393T>C	TOPMed,gnomAD
rs754090221	p.His852Arg	missense variant	-	NC_000010.11:g.89737396A>G	ExAC,gnomAD
rs762003553	p.Val853Phe	missense variant	-	NC_000010.11:g.89737398G>T	ExAC,TOPMed,gnomAD
rs765514704	p.Val853Ala	missense variant	-	NC_000010.11:g.89737399T>C	ExAC,TOPMed,gnomAD
COSM428114	p.Ser854Cys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737401A>T	NCI-TCGA Cosmic
rs750114333	p.Ser854Gly	missense variant	-	NC_000010.11:g.89737401A>G	ExAC,TOPMed,gnomAD
rs758239922	p.Ser855Leu	missense variant	-	NC_000010.11:g.89737405C>T	ExAC,TOPMed,gnomAD
rs370484351	p.Ala856Asp	missense variant	-	NC_000010.11:g.89737408C>A	ESP,ExAC,gnomAD
rs370484351	p.Ala856Val	missense variant	-	NC_000010.11:g.89737408C>T	ESP,ExAC,gnomAD
rs751544939	p.Ile857Val	missense variant	-	NC_000010.11:g.89737410A>G	ExAC,gnomAD
rs1252796663	p.Thr858Ile	missense variant	-	NC_000010.11:g.89737414C>T	gnomAD
rs1280489945	p.Gln861Arg	missense variant	-	NC_000010.11:g.89737423A>G	TOPMed
rs754451636	p.Ser864Thr	missense variant	-	NC_000010.11:g.89737432G>C	ExAC,gnomAD
rs1417349052	p.Ser864Cys	missense variant	-	NC_000010.11:g.89737431A>T	gnomAD
rs1379536336	p.Glu866Gln	missense variant	-	NC_000010.11:g.89737437G>C	gnomAD
rs79120882	p.Glu866Ala	missense variant	-	NC_000010.11:g.89737438A>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Glu866Lys	missense variant	-	NC_000010.11:g.89737437G>A	NCI-TCGA
rs747822069	p.Arg868Ter	stop gained	-	NC_000010.11:g.89737443C>T	ExAC,TOPMed,gnomAD
rs146050509	p.Arg868Gln	missense variant	-	NC_000010.11:g.89737444G>A	ESP,ExAC,TOPMed,gnomAD
rs1457068575	p.Pro869Thr	missense variant	-	NC_000010.11:g.89737446C>A	gnomAD
rs777512294	p.Pro869Leu	missense variant	-	NC_000010.11:g.89737447C>T	ExAC,TOPMed,gnomAD
rs1457068575	p.Pro869Ala	missense variant	-	NC_000010.11:g.89737446C>G	gnomAD
rs78963463	p.Asn870Ser	missense variant	-	NC_000010.11:g.89737450A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs114505265	p.Ile871Val	missense variant	-	NC_000010.11:g.89737452A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs375340649	p.Ile871Thr	missense variant	-	NC_000010.11:g.89737453T>C	ESP,ExAC,TOPMed,gnomAD
rs1248691006	p.Glu873Ala	missense variant	-	NC_000010.11:g.89737459A>C	gnomAD
rs768846216	p.Ile874Val	missense variant	-	NC_000010.11:g.89737461A>G	ExAC,gnomAD
rs1357880033	p.Ile874Met	missense variant	-	NC_000010.11:g.89737463T>G	TOPMed
rs776518445	p.Asp876Gly	missense variant	-	NC_000010.11:g.89737468A>G	ExAC,gnomAD
COSM921316	p.Asp876Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737467G>T	NCI-TCGA Cosmic
rs765334220	p.Ile877Leu	missense variant	-	NC_000010.11:g.89737470A>C	ExAC,gnomAD
rs750678256	p.Arg878Thr	missense variant	-	NC_000010.11:g.89737474G>C	ExAC,gnomAD
rs762711597	p.Val879Ile	missense variant	-	NC_000010.11:g.89737476G>A	ExAC,TOPMed
rs766200114	p.Gln881Arg	missense variant	-	NC_000010.11:g.89737483A>G	ExAC,TOPMed,gnomAD
rs938519006	p.Glu882Asp	missense variant	-	NC_000010.11:g.89737487A>C	TOPMed,gnomAD
NCI-TCGA novel	p.Asn883IlePheSerTerUnk	frameshift	-	NC_000010.11:g.89737489_89737511ATAATGAAGGACTGAGAGCATTT>-	NCI-TCGA
NCI-TCGA novel	p.Asn883His	missense variant	-	NC_000010.11:g.89737488A>C	NCI-TCGA
rs754966153	p.Glu885Lys	missense variant	-	NC_000010.11:g.89737494G>A	ExAC,gnomAD
rs752109208	p.Gly886Val	missense variant	-	NC_000010.11:g.89737498G>T	ExAC,gnomAD
rs781202563	p.Gly886Arg	missense variant	-	NC_000010.11:g.89737497G>A	ExAC,gnomAD
rs755673341	p.Arg888Thr	missense variant	-	NC_000010.11:g.89737504G>C	ExAC,gnomAD
rs146393515	p.Ala889Ser	missense variant	-	NC_000010.11:g.89737506G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs146393515	p.Ala889Thr	missense variant	-	NC_000010.11:g.89737506G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1188060483	p.Leu892His	missense variant	-	NC_000010.11:g.89737516T>A	TOPMed
rs368315164	p.Leu892Val	missense variant	-	NC_000010.11:g.89737515C>G	ESP,ExAC,TOPMed,gnomAD
rs372813515	p.Thr893Ile	missense variant	-	NC_000010.11:g.89737519C>T	ESP,ExAC,TOPMed,gnomAD
rs747394790	p.Ile894Val	missense variant	-	NC_000010.11:g.89737521A>G	ExAC,gnomAD
NCI-TCGA novel	p.Glu895Gln	missense variant	-	NC_000010.11:g.89737524G>C	NCI-TCGA
rs1176079556	p.Lys899Gln	missense variant	-	NC_000010.11:g.89737536A>C	gnomAD
rs201846033	p.Glu901Gly	missense variant	-	NC_000010.11:g.89737543A>G	ExAC,TOPMed,gnomAD
rs748124141	p.Lys902Glu	missense variant	-	NC_000010.11:g.89737545A>G	ExAC,TOPMed,gnomAD
rs769962290	p.Ala906Glu	missense variant	-	NC_000010.11:g.89737558C>A	ExAC,TOPMed,gnomAD
rs766148294	p.Asn909Ser	missense variant	-	NC_000010.11:g.89737567A>G	ExAC,TOPMed,gnomAD
rs766148294	p.Asn909Ile	missense variant	-	NC_000010.11:g.89737567A>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asn909Asp	missense variant	-	NC_000010.11:g.89737566A>G	NCI-TCGA
rs1482807052	p.Ile912Val	missense variant	-	NC_000010.11:g.89737575A>G	gnomAD
rs1286443862	p.Ile912Asn	missense variant	-	NC_000010.11:g.89737576T>A	TOPMed
rs1453907899	p.His914Asn	missense variant	-	NC_000010.11:g.89737581C>A	TOPMed
NCI-TCGA novel	p.Gln917CysSer	insertion	-	NC_000010.11:g.89737591_89737592insATGTTC	NCI-TCGA
rs774073640	p.Glu918Val	missense variant	-	NC_000010.11:g.89737594A>T	ExAC,gnomAD
rs1426337178	p.Leu919Val	missense variant	-	NC_000010.11:g.89737596C>G	gnomAD
rs1329645484	p.Ser920Pro	missense variant	-	NC_000010.11:g.89737599T>C	TOPMed
COSM6067290	p.Leu921Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737602C>G	NCI-TCGA Cosmic
rs759331085	p.Ser922Pro	missense variant	-	NC_000010.11:g.89737605T>C	ExAC,gnomAD
rs375938397	p.Lys924Arg	missense variant	-	NC_000010.11:g.89737612A>G	ESP,ExAC,gnomAD
COSM3415329	p.Lys925Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737616G>T	NCI-TCGA Cosmic
NCI-TCGA novel	p.Lys925ArgPheSerTerUnk	frameshift	-	NC_000010.11:g.89737609A>-	NCI-TCGA
rs752730939	p.Asn926Ser	missense variant	-	NC_000010.11:g.89737618A>G	ExAC
rs1365687384	p.Leu927Ter	stop gained	-	NC_000010.11:g.89737621T>G	gnomAD
rs763729318	p.Thr928Ala	missense variant	-	NC_000010.11:g.89737623A>G	ExAC,gnomAD
rs753530758	p.Ser930Thr	missense variant	-	NC_000010.11:g.89737630G>C	ExAC,TOPMed,gnomAD
rs1360179353	p.Lys931Glu	missense variant	-	NC_000010.11:g.89737632A>G	gnomAD
rs756914916	p.Glu932Ter	stop gained	-	NC_000010.11:g.89737635G>T	ExAC,TOPMed,gnomAD
rs756914916	p.Glu932Lys	missense variant	-	NC_000010.11:g.89737635G>A	ExAC,TOPMed,gnomAD
rs778717324	p.Val933Gly	missense variant	-	NC_000010.11:g.89737639T>G	ExAC,gnomAD
rs116910696	p.Gln937His	missense variant	-	NC_000010.11:g.89737652G>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs116910696	p.Gln937His	missense variant	-	NC_000010.11:g.89737652G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1245735389	p.Ser938Ter	stop gained	-	NC_000010.11:g.89737654C>G	TOPMed
rs369103401	p.Tyr940Asp	missense variant	-	NC_000010.11:g.89737659T>G	ESP,ExAC,TOPMed,gnomAD
rs1311512445	p.Asp941Gly	missense variant	-	NC_000010.11:g.89737663A>G	TOPMed,gnomAD
rs781525524	p.Asp941Asn	missense variant	-	NC_000010.11:g.89737662G>A	ExAC,gnomAD
rs1302020036	p.Ile942Thr	missense variant	-	NC_000010.11:g.89737666T>C	gnomAD
rs550934310	p.Ala945Thr	missense variant	-	NC_000010.11:g.89737674G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs1307561148	p.Leu947Ser	missense variant	-	NC_000010.11:g.89737681T>C	TOPMed
rs539858808	p.His948Pro	missense variant	-	NC_000010.11:g.89737684A>C	1000Genomes,ExAC,gnomAD
rs539858808	p.His948Arg	missense variant	-	NC_000010.11:g.89737684A>G	1000Genomes,ExAC,gnomAD
rs150024761	p.His948Tyr	missense variant	-	NC_000010.11:g.89737683C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs774578114	p.Val949Met	missense variant	-	NC_000010.11:g.89737686G>A	ExAC,TOPMed,gnomAD
rs774578114	p.Val949Leu	missense variant	-	NC_000010.11:g.89737686G>C	ExAC,TOPMed,gnomAD
rs1401759406	p.Gln950Lys	missense variant	-	NC_000010.11:g.89737689C>A	gnomAD
NCI-TCGA novel	p.Gln950HisPheSerTerUnkUnk	frameshift	-	NC_000010.11:g.89737689_89737690insATTTCTTA	NCI-TCGA
NCI-TCGA novel	p.Gln950PheArgPro	insertion	-	NC_000010.11:g.89737691_89737692insTTTCGTCCT	NCI-TCGA
rs759304471	p.Lys951Arg	missense variant	-	NC_000010.11:g.89737693A>G	ExAC
rs1343824202	p.Asn954Thr	missense variant	-	NC_000010.11:g.89737702A>C	gnomAD
NCI-TCGA novel	p.Asn954His	missense variant	-	NC_000010.11:g.89737701A>C	NCI-TCGA
COSM466067	p.Gln955Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737704C>A	NCI-TCGA Cosmic
COSM921318	p.Gln957His	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737712G>T	NCI-TCGA Cosmic
rs1276580891	p.Gln957Pro	missense variant	-	NC_000010.11:g.89737711A>C	gnomAD
rs775282828	p.Glu958Ter	stop gained	-	NC_000010.11:g.89737713G>T	ExAC,gnomAD
rs775282828	p.Glu958Lys	missense variant	-	NC_000010.11:g.89737713G>A	ExAC,gnomAD
rs760720747	p.Glu958Val	missense variant	-	NC_000010.11:g.89737714A>T	ExAC,gnomAD
rs763948311	p.Glu959Asp	missense variant	-	NC_000010.11:g.89737718A>C	ExAC,TOPMed,gnomAD
rs1351694051	p.Lys960Glu	missense variant	-	NC_000010.11:g.89737719A>G	TOPMed
COSM1321985	p.Lys960Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737721G>T	NCI-TCGA Cosmic
rs1274302530	p.Lys960Arg	missense variant	-	NC_000010.11:g.89737720A>G	gnomAD
rs144947333	p.Ile961Met	missense variant	-	NC_000010.11:g.89737724C>G	ESP,ExAC,TOPMed,gnomAD
rs753328541	p.Ile961Val	missense variant	-	NC_000010.11:g.89737722A>G	ExAC,TOPMed,gnomAD
rs1220465776	p.Met962Val	missense variant	-	NC_000010.11:g.89737725A>G	gnomAD
rs375953320	p.Asn966His	missense variant	-	NC_000010.11:g.89737737A>C	ESP,TOPMed,gnomAD
rs375953320	p.Asn966Asp	missense variant	-	NC_000010.11:g.89737737A>G	ESP,TOPMed,gnomAD
rs1419426176	p.Ile968Thr	missense variant	-	NC_000010.11:g.89737744T>C	TOPMed
rs1489218050	p.Thr972Ile	missense variant	-	NC_000010.11:g.89737756C>T	TOPMed
rs1024644135	p.Arg973Gly	missense variant	-	NC_000010.11:g.89737758A>G	TOPMed
COSM921319	p.Arg973Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737759G>T	NCI-TCGA Cosmic
rs1489227857	p.Ser974Thr	missense variant	-	NC_000010.11:g.89737762G>C	gnomAD
COSM257235	p.Ser974Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737762G>A	NCI-TCGA Cosmic
rs199626794	p.Ile975Val	missense variant	-	NC_000010.11:g.89737764A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs755269444	p.Ile975Asn	missense variant	-	NC_000010.11:g.89737765T>A	ExAC,gnomAD
rs149051114	p.Thr976Ile	missense variant	-	NC_000010.11:g.89737768C>T	ESP,ExAC,TOPMed,gnomAD
rs753133210	p.Asn977Tyr	missense variant	-	NC_000010.11:g.89737770A>T	ExAC,gnomAD
rs753133210	p.Asn977Asp	missense variant	-	NC_000010.11:g.89737770A>G	ExAC,gnomAD
NCI-TCGA novel	p.Ile982Val	missense variant	-	NC_000010.11:g.89737785A>G	NCI-TCGA
rs1378934225	p.Ile982Met	missense variant	-	NC_000010.11:g.89737787A>G	gnomAD
rs573380739	p.Met985Val	missense variant	-	NC_000010.11:g.89737794A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs536047150	p.Met985Thr	missense variant	-	NC_000010.11:g.89737795T>C	1000Genomes,ExAC,TOPMed,gnomAD
rs771048255	p.His986Tyr	missense variant	-	NC_000010.11:g.89737797C>T	ExAC,TOPMed,gnomAD
rs779075638	p.Thr987Met	missense variant	-	NC_000010.11:g.89737801C>T	ExAC,TOPMed,gnomAD
rs147780471	p.Lys988Asn	missense variant	-	NC_000010.11:g.89737805A>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs775294446	p.Ile989Val	missense variant	-	NC_000010.11:g.89737806A>G	ExAC,TOPMed,gnomAD
rs760387684	p.Ile989Met	missense variant	-	NC_000010.11:g.89737808A>G	ExAC,gnomAD
rs1281281711	p.Ile989Thr	missense variant	-	NC_000010.11:g.89737807T>C	gnomAD
rs768593820	p.Asp990Gly	missense variant	-	NC_000010.11:g.89737810A>G	ExAC,gnomAD
rs761389049	p.Glu991Lys	missense variant	-	NC_000010.11:g.89737812G>A	ExAC,TOPMed,gnomAD
rs764883701	p.Glu991Gly	missense variant	-	NC_000010.11:g.89737813A>G	ExAC,gnomAD
rs373614828	p.Glu991Asp	missense variant	-	NC_000010.11:g.89737814A>T	1000Genomes,ExAC,TOPMed,gnomAD
rs762726364	p.Leu992Pro	missense variant	-	NC_000010.11:g.89737816T>C	ExAC,TOPMed,gnomAD
rs771883789	p.Arg993Pro	missense variant	-	NC_000010.11:g.89737819G>C	ExAC,TOPMed,gnomAD
rs765962967	p.Arg993Cys	missense variant	-	NC_000010.11:g.89737818C>T	ExAC,gnomAD
COSM921320	p.Arg993ValPheSerTerUnkUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89737818C>-	NCI-TCGA Cosmic
rs771883789	p.Arg993His	missense variant	-	NC_000010.11:g.89737819G>A	ExAC,TOPMed,gnomAD
rs756466212	p.Leu995Phe	missense variant	-	NC_000010.11:g.89737824C>T	ExAC,gnomAD
rs1051925305	p.Ser997Leu	missense variant	-	NC_000010.11:g.89737831C>T	gnomAD
rs1051925305	p.Ser997Ter	stop gained	-	NC_000010.11:g.89737831C>G	gnomAD
NCI-TCGA novel	p.Ser999Phe	missense variant	-	NC_000010.11:g.89737837C>T	NCI-TCGA
rs754382182	p.Ile1001Val	missense variant	-	NC_000010.11:g.89737842A>G	ExAC,TOPMed,gnomAD
rs757323881	p.Ile1001Met	missense variant	-	NC_000010.11:g.89737844T>G	ExAC,gnomAD
rs1397484102	p.Ile1001Thr	missense variant	-	NC_000010.11:g.89737843T>C	gnomAD
rs34999049	p.Asn1003Asp	missense variant	-	NC_000010.11:g.89737848A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1476547878	p.Asn1003Ser	missense variant	-	NC_000010.11:g.89737849A>G	TOPMed
rs759603637	p.Ile1004ArgPheSerTerUnkUnk	frameshift	-	NC_000010.11:g.89737851_89737852AT>-	NCI-TCGA
rs745947393	p.Asp1005Ala	missense variant	-	NC_000010.11:g.89737855A>C	ExAC,TOPMed,gnomAD
rs1384741968	p.Leu1006Phe	missense variant	-	NC_000010.11:g.89737859G>T	gnomAD
rs1315583361	p.Leu1006Ter	stop gained	-	NC_000010.11:g.89737858T>A	gnomAD
rs1384741968	p.Leu1006Phe	missense variant	-	NC_000010.11:g.89737859G>C	gnomAD
rs760311235	p.Leu1007His	missense variant	-	NC_000010.11:g.89737861T>A	ExAC,TOPMed,gnomAD
rs1215858463	p.Asn1008Ser	missense variant	-	NC_000010.11:g.89737864A>G	TOPMed,gnomAD
rs768625398	p.Asn1008Asp	missense variant	-	NC_000010.11:g.89737863A>G	ExAC,gnomAD
rs148049931	p.Leu1009Phe	missense variant	-	NC_000010.11:g.89737866C>T	ESP,ExAC,TOPMed,gnomAD
rs1208416129	p.Leu1009Arg	missense variant	-	NC_000010.11:g.89737867T>G	TOPMed
rs1062465	p.Asp1011Glu	missense variant	-	NC_000010.11:g.89737874T>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1441119412	p.Ser1013Ala	missense variant	-	NC_000010.11:g.89737878T>G	TOPMed,gnomAD
NCI-TCGA novel	p.Ser1013Ter	stop gained	-	NC_000010.11:g.89737879C>G	NCI-TCGA
COSM921321	p.Asn1020Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737900A>C	NCI-TCGA Cosmic
rs762375702	p.Leu1021Ser	missense variant	-	NC_000010.11:g.89737903T>C	ExAC,TOPMed,gnomAD
rs751194437	p.Asn1023His	missense variant	-	NC_000010.11:g.89737908A>C	ExAC,gnomAD
rs1378286762	p.Asn1023Ser	missense variant	-	NC_000010.11:g.89737909A>G	TOPMed
rs1470309561	p.Thr1024Ile	missense variant	-	NC_000010.11:g.89737912C>T	gnomAD
COSM686124	p.Thr1024Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737911A>G	NCI-TCGA Cosmic
rs764509050	p.Asn1031Ser	missense variant	-	NC_000010.11:g.89737933A>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asn1031Asp	missense variant	-	NC_000010.11:g.89737932A>G	NCI-TCGA
rs757702483	p.Tyr1033Phe	missense variant	-	NC_000010.11:g.89737939A>T	ExAC,gnomAD
rs1316756789	p.Leu1034Ser	missense variant	-	NC_000010.11:g.89737942T>C	gnomAD
rs765735174	p.Ser1036Thr	missense variant	-	NC_000010.11:g.89737948G>C	ExAC,TOPMed,gnomAD
rs765735174	p.Ser1036Ile	missense variant	-	NC_000010.11:g.89737948G>T	ExAC,TOPMed,gnomAD
rs758425932	p.Gln1038Arg	missense variant	-	NC_000010.11:g.89737954A>G	ExAC,gnomAD
rs750472714	p.Gln1038Glu	missense variant	-	NC_000010.11:g.89737953C>G	ExAC,gnomAD
rs1429664350	p.Lys1040Arg	missense variant	-	NC_000010.11:g.89737960A>G	TOPMed
rs1463164504	p.Glu1041Lys	missense variant	-	NC_000010.11:g.89737962G>A	gnomAD
NCI-TCGA novel	p.Glu1041Ala	missense variant	-	NC_000010.11:g.89737963A>C	NCI-TCGA
rs780296597	p.Tyr1042His	missense variant	-	NC_000010.11:g.89737965T>C	ExAC,gnomAD
rs369579248	p.Tyr1042Cys	missense variant	-	NC_000010.11:g.89737966A>G	ESP,ExAC,gnomAD
rs371655633	p.Arg1043Gln	missense variant	-	NC_000010.11:g.89737969G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs150367819	p.Arg1043Ter	stop gained	-	NC_000010.11:g.89737968C>T	ExAC,gnomAD
rs371655633	p.Arg1043Leu	missense variant	-	NC_000010.11:g.89737969G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs375178802	p.Glu1046Asp	missense variant	-	NC_000010.11:g.89737979A>C	ESP,ExAC,TOPMed,gnomAD
rs748783218	p.Pro1047His	missense variant	-	NC_000010.11:g.89737981C>A	ExAC,gnomAD
rs774047998	p.Asn1048Ser	missense variant	-	NC_000010.11:g.89737984A>G	ExAC,TOPMed,gnomAD
rs770386949	p.Asn1048Asp	missense variant	-	NC_000010.11:g.89737983A>G	ExAC,gnomAD
rs774047998	p.Asn1048Ile	missense variant	-	NC_000010.11:g.89737984A>T	ExAC,TOPMed,gnomAD
rs767167656	p.Arg1049Gly	missense variant	-	NC_000010.11:g.89737986A>G	ExAC,gnomAD
NCI-TCGA novel	p.Asn1051Ser	missense variant	-	NC_000010.11:g.89737993A>G	NCI-TCGA
rs776912439	p.Ser1052Tyr	missense variant	-	NC_000010.11:g.89737996C>A	ExAC,gnomAD
COSM3441434	p.Ser1052Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89737996C>T	NCI-TCGA Cosmic
rs1296038031	p.His1054Arg	missense variant	-	NC_000010.11:g.89738002A>G	gnomAD
rs765680007	p.Ser1056Thr	missense variant	-	NC_000010.11:g.89738008G>C	ExAC,gnomAD
rs765680007	p.Ser1056Ile	missense variant	-	NC_000010.11:g.89738008G>T	ExAC,gnomAD
rs1302731113	p.Ile1057Ser	missense variant	-	NC_000010.11:g.89738011T>G	TOPMed,gnomAD
rs758477425	p.Ala1059Thr	missense variant	-	NC_000010.11:g.89738016G>A	ExAC,gnomAD
rs766439713	p.Trp1061Ser	missense variant	-	NC_000010.11:g.89738023G>C	ExAC,TOPMed,gnomAD
rs1353290708	p.Glu1062Ter	stop gained	-	NC_000010.11:g.89738025G>T	gnomAD
rs1024742853	p.Cys1064Gly	missense variant	-	NC_000010.11:g.89738031T>G	TOPMed
rs373589296	p.Glu1066Asp	missense variant	-	NC_000010.11:g.89738039G>C	ESP,ExAC,TOPMed,gnomAD
rs1490568537	p.Ile1067Val	missense variant	-	NC_000010.11:g.89738040A>G	TOPMed,gnomAD
rs138228331	p.Ala1070Ser	missense variant	-	NC_000010.11:g.89738049G>T	ESP,ExAC,TOPMed,gnomAD
rs541996453	p.Ala1070Gly	missense variant	-	NC_000010.11:g.89738050C>G	1000Genomes
rs138228331	p.Ala1070Thr	missense variant	-	NC_000010.11:g.89738049G>A	ESP,ExAC,TOPMed,gnomAD
rs138228331	p.Ala1070Pro	missense variant	-	NC_000010.11:g.89738049G>C	ESP,ExAC,TOPMed,gnomAD
COSM4821027	p.Ser1071Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89738053C>T	NCI-TCGA Cosmic
rs777744964	p.Lys1073Gln	missense variant	-	NC_000010.11:g.89738058A>C	ExAC,TOPMed,gnomAD
rs770460815	p.Lys1074Asn	missense variant	-	NC_000010.11:g.89738063A>C	ExAC,gnomAD
rs201617733	p.Ser1075Asn	missense variant	-	NC_000010.11:g.89738065G>A	1000Genomes,ExAC,TOPMed,gnomAD
COSM1968953	p.Ser1075ValPheSerTerUnkUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89738058A>-	NCI-TCGA Cosmic
rs745385361	p.Ser1075Gly	missense variant	-	NC_000010.11:g.89738064A>G	ExAC,gnomAD
rs367727797	p.His1076Arg	missense variant	-	NC_000010.11:g.89738068A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.His1076Pro	missense variant	-	NC_000010.11:g.89738068A>C	NCI-TCGA
rs1368450473	p.Gln1077Pro	missense variant	-	NC_000010.11:g.89738071A>C	TOPMed
rs762140094	p.Ile1078Asn	missense variant	-	NC_000010.11:g.89738074T>A	ExAC,TOPMed,gnomAD
rs765556365	p.Leu1081Met	missense variant	-	NC_000010.11:g.89738082C>A	ExAC,gnomAD
rs765556365	p.Leu1081Val	missense variant	-	NC_000010.11:g.89738082C>G	ExAC,gnomAD
rs1360557001	p.Ile1085Thr	missense variant	-	NC_000010.11:g.89738095T>C	gnomAD
rs1308948786	p.Ile1085Val	missense variant	-	NC_000010.11:g.89738094A>G	gnomAD
rs1224067292	p.Glu1086Gly	missense variant	-	NC_000010.11:g.89738098A>G	gnomAD
rs1263838173	p.Gln1089Ter	stop gained	-	NC_000010.11:g.89738106C>T	gnomAD
rs766927016	p.Ala1090Thr	missense variant	-	NC_000010.11:g.89738109G>A	ExAC,gnomAD
rs1196445111	p.Val1092Ile	missense variant	-	NC_000010.11:g.89738115G>A	TOPMed,gnomAD
rs1355725713	p.Lys1093Glu	missense variant	-	NC_000010.11:g.89738118A>G	TOPMed
rs142890695	p.Tyr1095Phe	missense variant	-	NC_000010.11:g.89738125A>T	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Tyr1095Ter	stop gained	-	NC_000010.11:g.89738123_89738124insTAACTGTG	NCI-TCGA
rs142890695	p.Tyr1095Cys	missense variant	-	NC_000010.11:g.89738125A>G	ESP,ExAC,TOPMed,gnomAD
rs973425017	p.Lys1096Thr	missense variant	-	NC_000010.11:g.89738128A>C	TOPMed
rs767799601	p.Asn1099Lys	missense variant	-	NC_000010.11:g.89738138C>G	ExAC,TOPMed,gnomAD
rs1379475423	p.Asn1099Ile	missense variant	-	NC_000010.11:g.89738137A>T	gnomAD
rs114371507	p.Asn1100Ser	missense variant	-	NC_000010.11:g.89738140A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs114371507	p.Asn1100Ile	missense variant	-	NC_000010.11:g.89738140A>T	1000Genomes,ExAC,TOPMed,gnomAD
rs78400882	p.Leu1102Val	missense variant	-	NC_000010.11:g.89738145C>G	ExAC,TOPMed
rs76057302	p.Lys1103Asn	missense variant	-	NC_000010.11:g.89738150G>C	ExAC,gnomAD
NCI-TCGA novel	p.Glu1104Asp	missense variant	-	NC_000010.11:g.89738153G>T	NCI-TCGA
rs79579856	p.Lys1105Arg	missense variant	-	NC_000010.11:g.89738155A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs779646473	p.Gln1110Arg	missense variant	-	NC_000010.11:g.89738170A>G	ExAC,TOPMed,gnomAD
rs1386362544	p.Leu1113Ile	missense variant	-	NC_000010.11:g.89738178C>A	TOPMed
COSM6130875	p.Leu1113Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89738178C>G	NCI-TCGA Cosmic
rs1310923650	p.Leu1113Arg	missense variant	-	NC_000010.11:g.89738179T>G	gnomAD
rs746735387	p.Lys1115Glu	missense variant	-	NC_000010.11:g.89738184A>G	ExAC,gnomAD
rs766853715	p.Glu1116Gly	missense variant	-	NC_000010.11:g.89738188A>G	TOPMed,gnomAD
COSM4826927	p.Glu1118Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89738193G>C	NCI-TCGA Cosmic
rs770185093	p.Thr1119Ala	missense variant	-	NC_000010.11:g.89738196A>G	ExAC,gnomAD
rs773394311	p.Thr1119Ser	missense variant	-	NC_000010.11:g.89738197C>G	ExAC,gnomAD
rs763383909	p.Leu1120Val	missense variant	-	NC_000010.11:g.89738199C>G	ExAC,TOPMed,gnomAD
rs368304916	p.Ile1121Thr	missense variant	-	NC_000010.11:g.89738203T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs931445688	p.Ile1121Leu	missense variant	-	NC_000010.11:g.89738202A>T	TOPMed,gnomAD
rs147954246	p.Ile1121Met	missense variant	-	NC_000010.11:g.89738204A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs368304916	p.Ile1121Arg	missense variant	-	NC_000010.11:g.89738203T>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs767746356	p.Gln1123Arg	missense variant	-	NC_000010.11:g.89738209A>G	ExAC,gnomAD
rs752953055	p.Leu1124Met	missense variant	-	NC_000010.11:g.89738211C>A	ExAC,gnomAD
COSM289711	p.Glu1126Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89738217G>T	NCI-TCGA Cosmic
rs11185863	p.Glu1127Gln	missense variant	-	NC_000010.11:g.89738220G>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1301432885	p.Leu1128Met	missense variant	-	NC_000010.11:g.89738223T>A	gnomAD
rs1046481107	p.Leu1128Trp	missense variant	-	NC_000010.11:g.89738224T>G	TOPMed,gnomAD
rs904983259	p.Gln1129Arg	missense variant	-	NC_000010.11:g.89738227A>G	TOPMed
rs998507213	p.Gln1129Ter	stop gained	-	NC_000010.11:g.89738226C>T	TOPMed,gnomAD
rs778690180	p.Glu1130Gly	missense variant	-	NC_000010.11:g.89738230A>G	ExAC,TOPMed,gnomAD
rs750396763	p.Glu1130Asp	missense variant	-	NC_000010.11:g.89738231A>T	ExAC,TOPMed,gnomAD
rs757094581	p.Glu1130Lys	missense variant	-	NC_000010.11:g.89738229G>A	ExAC
rs141907832	p.Lys1131Glu	missense variant	-	NC_000010.11:g.89738232A>G	1000Genomes,ExAC,gnomAD
rs1212021499	p.Asn1132Tyr	missense variant	-	NC_000010.11:g.89738235A>T	gnomAD
rs1002366189	p.Asn1132Lys	missense variant	-	NC_000010.11:g.89738237T>A	TOPMed,gnomAD
COSM1722154	p.Asn1132MetPheSerTerUnkUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89738230A>-	NCI-TCGA Cosmic
rs1232096793	p.Asn1132Ser	missense variant	-	NC_000010.11:g.89738236A>G	TOPMed
rs1053507629	p.Thr1134Ile	missense variant	-	NC_000010.11:g.89738242C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Thr1134Asn	missense variant	-	NC_000010.11:g.89738242C>A	NCI-TCGA
rs568672822	p.Leu1135Pro	missense variant	-	NC_000010.11:g.89738245T>C	ExAC,gnomAD
rs141950040	p.Asp1136Asn	missense variant	-	NC_000010.11:g.89738247G>A	ESP,ExAC,TOPMed,gnomAD
rs1192276884	p.Ile1139Thr	missense variant	-	NC_000010.11:g.89738257T>C	gnomAD
rs1366788261	p.Ile1139Val	missense variant	-	NC_000010.11:g.89738256A>G	TOPMed
COSM3807957	p.Gln1140Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89738259C>T	NCI-TCGA Cosmic
rs148573019	p.His1141Gln	missense variant	-	NC_000010.11:g.89738264T>G	ESP,ExAC,TOPMed,gnomAD
rs1298110902	p.His1141Asp	missense variant	-	NC_000010.11:g.89738262C>G	TOPMed
rs144843486	p.His1141Arg	missense variant	-	NC_000010.11:g.89738263A>G	ESP,ExAC,TOPMed,gnomAD
rs1455802714	p.Val1142Ile	missense variant	-	NC_000010.11:g.89738265G>A	gnomAD
rs1416686417	p.Val1142Ala	missense variant	-	NC_000010.11:g.89738266T>C	gnomAD
rs760178295	p.Lys1146Arg	missense variant	-	NC_000010.11:g.89738278A>G	ExAC,gnomAD
rs772720230	p.Arg1147Lys	missense variant	-	NC_000010.11:g.89738281G>A	ExAC,gnomAD
rs1477839486	p.Arg1147Ser	missense variant	-	NC_000010.11:g.89738282A>C	TOPMed
rs775642819	p.Ala1148Thr	missense variant	-	NC_000010.11:g.89738283G>A	ExAC,TOPMed,gnomAD
rs117564945	p.Ala1148Val	missense variant	-	NC_000010.11:g.89738284C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs761478881	p.Leu1149Phe	missense variant	-	NC_000010.11:g.89738286C>T	ExAC,gnomAD
COSM3397293	p.Leu1152Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89738295C>A	NCI-TCGA Cosmic
rs1026349230	p.Thr1153Ile	missense variant	-	NC_000010.11:g.89738299C>T	TOPMed
rs1026349230	p.Thr1153Lys	missense variant	-	NC_000010.11:g.89738299C>A	TOPMed
rs150657646	p.Gln1154Arg	missense variant	-	NC_000010.11:g.89738302A>G	ESP,gnomAD
rs1311459555	p.Gly1155Arg	missense variant	-	NC_000010.11:g.89738304G>C	gnomAD
COSM921323	p.Val1156Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89738308T>C	NCI-TCGA Cosmic
rs373468932	p.Thr1157Ile	missense variant	-	NC_000010.11:g.89738311C>T	ESP,TOPMed
rs577918687	p.Tyr1159Ser	missense variant	-	NC_000010.11:g.89738317A>C	1000Genomes,ExAC,TOPMed,gnomAD
rs577918687	p.Tyr1159Cys	missense variant	-	NC_000010.11:g.89738317A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs557988714	p.Tyr1159His	missense variant	-	NC_000010.11:g.89738316T>C	1000Genomes,ExAC,TOPMed,gnomAD
rs751032264	p.Lys1160Glu	missense variant	-	NC_000010.11:g.89738319A>G	ExAC,gnomAD
rs1246809989	p.Lys1162Asn	missense variant	-	NC_000010.11:g.89738327A>T	gnomAD
rs754539821	p.Lys1162Glu	missense variant	-	NC_000010.11:g.89738325A>G	ExAC,gnomAD
rs780688492	p.Ile1163Val	missense variant	-	NC_000010.11:g.89738328A>G	ExAC,TOPMed,gnomAD
rs1264594745	p.Lys1164Arg	missense variant	-	NC_000010.11:g.89738332A>G	TOPMed
NCI-TCGA novel	p.Glu1165Asp	missense variant	-	NC_000010.11:g.89738336A>C	NCI-TCGA
rs747875200	p.Glu1167Gln	missense variant	-	NC_000010.11:g.89738340G>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ile1169Leu	missense variant	-	NC_000010.11:g.89738346A>C	NCI-TCGA
rs779361610	p.Thr1172Ala	missense variant	-	NC_000010.11:g.89738355A>G	ExAC,gnomAD
rs746239771	p.Gln1173Arg	missense variant	-	NC_000010.11:g.89738359A>G	ExAC,TOPMed,gnomAD
rs1886996	p.Cys1177Ser	missense variant	-	NC_000010.11:g.89738370T>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1886996	p.Cys1177Arg	missense variant	-	NC_000010.11:g.89738370T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs202221525	p.Cys1177Tyr	missense variant	-	NC_000010.11:g.89738371G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs747034628	p.His1179Tyr	missense variant	-	NC_000010.11:g.89738376C>T	ExAC,gnomAD
rs747034628	p.His1179Asn	missense variant	-	NC_000010.11:g.89738376C>A	ExAC,gnomAD
rs1178839875	p.His1179Gln	missense variant	-	NC_000010.11:g.89738378T>A	TOPMed
rs776710112	p.Ala1181Thr	missense variant	-	NC_000010.11:g.89738382G>A	ExAC,gnomAD
rs762149860	p.Glu1184Ala	missense variant	-	NC_000010.11:g.89738392A>C	ExAC,gnomAD
NCI-TCGA novel	p.Glu1184Lys	missense variant	-	NC_000010.11:g.89738391G>A	NCI-TCGA
rs147796970	p.Gln1185Glu	missense variant	-	NC_000010.11:g.89738394C>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1290070475	p.Asp1186Glu	missense variant	-	NC_000010.11:g.89738399C>G	TOPMed,gnomAD
rs772928928	p.Lys1190Thr	missense variant	-	NC_000010.11:g.89738410A>C	ExAC,gnomAD
rs766259228	p.Glu1191Ala	missense variant	-	NC_000010.11:g.89738413A>C	ExAC,TOPMed,gnomAD
rs762770718	p.Glu1191Gln	missense variant	-	NC_000010.11:g.89738412G>C	ExAC,gnomAD
NCI-TCGA novel	p.Glu1191Lys	missense variant	-	NC_000010.11:g.89738412G>A	NCI-TCGA
rs375369186	p.Ile1193Met	missense variant	-	NC_000010.11:g.89738420C>G	ESP,ExAC,TOPMed,gnomAD
rs201445803	p.Ile1193Val	missense variant	-	NC_000010.11:g.89738418A>G	TOPMed,gnomAD
rs754417788	p.Ile1194Val	missense variant	-	NC_000010.11:g.89738421A>G	ExAC,gnomAD
NCI-TCGA novel	p.Ile1194Thr	missense variant	-	NC_000010.11:g.89738422T>C	NCI-TCGA
rs1164118371	p.Leu1195Ile	missense variant	-	NC_000010.11:g.89738424T>A	TOPMed,gnomAD
rs139497016	p.Leu1197Pro	missense variant	-	NC_000010.11:g.89738431T>C	ESP,ExAC,gnomAD
rs755760483	p.Glu1198Asp	missense variant	-	NC_000010.11:g.89738435A>T	ExAC,gnomAD
NCI-TCGA novel	p.Arg1199Lys	missense variant	-	NC_000010.11:g.89738437G>A	NCI-TCGA
rs1447456206	p.Asn1200Lys	missense variant	-	NC_000010.11:g.89738441T>G	gnomAD
rs777598313	p.Asn1200His	missense variant	-	NC_000010.11:g.89738439A>C	ExAC,gnomAD
COSM3397295	p.Asn1200Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89738439A>G	NCI-TCGA Cosmic
rs1212079702	p.Leu1201Ser	missense variant	-	NC_000010.11:g.89738443T>C	gnomAD
rs746184816	p.Lys1202Glu	missense variant	-	NC_000010.11:g.89738445A>G	ExAC,TOPMed,gnomAD
rs758880025	p.Lys1202Arg	missense variant	-	NC_000010.11:g.89738446A>G	ExAC,gnomAD
COSM3441438	p.Gln1205Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89738454C>T	NCI-TCGA Cosmic
rs780673592	p.His1207Leu	missense variant	-	NC_000010.11:g.89738461A>T	ExAC,gnomAD
rs777701651	p.His1207Gln	missense variant	-	NC_000010.11:g.89738462T>G	TOPMed
rs1215781303	p.Leu1208Phe	missense variant	-	NC_000010.11:g.89738463C>T	TOPMed
rs747614030	p.Leu1208Pro	missense variant	-	NC_000010.11:g.89738464T>C	ExAC,TOPMed,gnomAD
rs1471768031	p.Gln1209Ter	stop gained	-	NC_000010.11:g.89738466C>T	gnomAD
rs144980311	p.Ser1211Pro	missense variant	-	NC_000010.11:g.89738472T>C	ESP,ExAC,TOPMed,gnomAD
rs147115055	p.Val1212Phe	missense variant	-	NC_000010.11:g.89738475G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs147115055	p.Val1212Ile	missense variant	-	NC_000010.11:g.89738475G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs373055860	p.Lys1213Arg	missense variant	-	NC_000010.11:g.89738479A>G	ESP,TOPMed,gnomAD
rs1201088465	p.Lys1213Gln	missense variant	-	NC_000010.11:g.89738478A>C	gnomAD
COSM1638678	p.Asn1214ThrPheSerTerUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89738478A>-	NCI-TCGA Cosmic
rs1457645691	p.Asn1214Asp	missense variant	-	NC_000010.11:g.89738481A>G	TOPMed,gnomAD
rs149103168	p.Lys1216Glu	missense variant	-	NC_000010.11:g.89738487A>G	ESP,ExAC,TOPMed,gnomAD
rs1168674673	p.Lys1216Arg	missense variant	-	NC_000010.11:g.89738488A>G	TOPMed
NCI-TCGA novel	p.Asp1217Tyr	missense variant	-	NC_000010.11:g.89738490G>T	NCI-TCGA
rs762715615	p.Asn1219Lys	missense variant	-	NC_000010.11:g.89738498T>A	ExAC
rs1886997	p.Asn1219Ser	missense variant	-	NC_000010.11:g.89738497A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1886997	p.Asn1219Thr	missense variant	-	NC_000010.11:g.89738497A>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs770754356	p.Val1220Ile	missense variant	-	NC_000010.11:g.89738499G>A	ExAC,gnomAD
COSM3967209	p.Leu1223Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89738508C>T	NCI-TCGA Cosmic
rs767360842	p.Lys1224Arg	missense variant	-	NC_000010.11:g.89738512A>G	ExAC,TOPMed,gnomAD
rs151203510	p.Leu1225Pro	missense variant	-	NC_000010.11:g.89738515T>C	ESP,TOPMed,gnomAD
rs140341168	p.Glu1227Val	missense variant	-	NC_000010.11:g.89738521A>T	ESP,ExAC,TOPMed,gnomAD
COSM261661	p.Glu1227Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89738520G>T	NCI-TCGA Cosmic
COSM4016545	p.Glu1228Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89738523G>T	NCI-TCGA Cosmic
rs1445385468	p.Ile1229Ser	missense variant	-	NC_000010.11:g.89738527T>G	gnomAD
rs1235951315	p.Ile1229Leu	missense variant	-	NC_000010.11:g.89738526A>C	TOPMed
rs1437897090	p.Gln1231Ter	stop gained	-	NC_000010.11:g.89738532C>T	TOPMed
rs753582024	p.Asn1235Ser	missense variant	-	NC_000010.11:g.89738545A>G	ExAC,gnomAD
rs758828483	p.Leu1236Phe	missense variant	-	NC_000010.11:g.89738549G>T	ExAC,gnomAD
rs1411347324	p.Gln1237Pro	missense variant	-	NC_000010.11:g.89738551A>C	gnomAD
rs751880293	p.Asp1238His	missense variant	-	NC_000010.11:g.89738553G>C	ExAC,gnomAD
rs1330085204	p.Met1239Lys	missense variant	-	NC_000010.11:g.89738557T>A	gnomAD
rs755450200	p.Met1239Ile	missense variant	-	NC_000010.11:g.89738558G>A	ExAC,gnomAD
rs1440996054	p.Lys1240Arg	missense variant	-	NC_000010.11:g.89738560A>G	gnomAD
NCI-TCGA novel	p.Lys1240Thr	missense variant	-	NC_000010.11:g.89738560A>C	NCI-TCGA
rs376561901	p.His1241Arg	missense variant	-	NC_000010.11:g.89738563A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs1357865631	p.His1241Asp	missense variant	-	NC_000010.11:g.89738562C>G	TOPMed
rs376561901	p.His1241Pro	missense variant	-	NC_000010.11:g.89738563A>C	1000Genomes,ExAC,TOPMed,gnomAD
rs187783613	p.Leu1242Ser	missense variant	-	NC_000010.11:g.89738566T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1274458736	p.Leu1243Phe	missense variant	-	NC_000010.11:g.89738568C>T	gnomAD
rs373556748	p.Gln1244Pro	missense variant	-	NC_000010.11:g.89738572A>C	ESP,ExAC,TOPMed,gnomAD
rs373556748	p.Gln1244Arg	missense variant	-	NC_000010.11:g.89738572A>G	ESP,ExAC,TOPMed,gnomAD
rs1461445982	p.Gln1244His	missense variant	-	NC_000010.11:g.89738573A>C	gnomAD
rs749579155	p.Gln1244Lys	missense variant	-	NC_000010.11:g.89738571C>A	ExAC,gnomAD
rs1009232296	p.Leu1245Val	missense variant	-	NC_000010.11:g.89738574T>G	TOPMed,gnomAD
NCI-TCGA novel	p.Leu1245Ile	missense variant	-	NC_000010.11:g.89738574T>A	NCI-TCGA
COSM3985810	p.Glu1247Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89738581A>C	NCI-TCGA Cosmic
NCI-TCGA novel	p.Glu1250Ter	stop gained	-	NC_000010.11:g.89738589G>T	NCI-TCGA
rs766729878	p.GluThr1251GluLysTerTerLeuHisSerGluGluThrTerGlnIleProLeuTerUnk	stop gained	-	NC_000010.11:g.89738595_89738596insAATAATAACTTCATAGTGAAGAAACCTAGCAGATACCACTTTAA	ExAC,gnomAD
rs775337894	p.Asn1253Ser	missense variant	-	NC_000010.11:g.89738599A>G	ExAC,TOPMed,gnomAD
rs760227696	p.Asn1253Lys	missense variant	-	NC_000010.11:g.89738600C>A	ExAC,gnomAD
rs375682004	p.Arg1254Gly	missense variant	-	NC_000010.11:g.89738601A>G	ESP,ExAC,TOPMed,gnomAD
rs1027047459	p.Arg1254Lys	missense variant	-	NC_000010.11:g.89738602G>A	TOPMed
rs1234625222	p.Glu1258Val	missense variant	-	NC_000010.11:g.89738614A>T	gnomAD
rs751914239	p.Lys1259Glu	missense variant	-	NC_000010.11:g.89738616A>G	ExAC,gnomAD
rs544410846	p.Lys1261Arg	missense variant	-	NC_000010.11:g.89738963A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs544410846	p.Lys1261Thr	missense variant	-	NC_000010.11:g.89738963A>C	1000Genomes,ExAC,TOPMed,gnomAD
rs756556741	p.Glu1262Asp	missense variant	-	NC_000010.11:g.89738967G>C	ExAC,gnomAD
rs1387906177	p.Glu1262Gly	missense variant	-	NC_000010.11:g.89738966A>G	gnomAD
rs1320996745	p.Glu1263Gly	missense variant	-	NC_000010.11:g.89738969A>G	TOPMed
NCI-TCGA novel	p.Ser1265Pro	missense variant	-	NC_000010.11:g.89738974T>C	NCI-TCGA
rs753864053	p.Ala1266Val	missense variant	-	NC_000010.11:g.89738978C>T	ExAC,TOPMed,gnomAD
rs1306631899	p.Ser1268Cys	missense variant	-	NC_000010.11:g.89738984C>G	gnomAD
NCI-TCGA novel	p.Ser1268Phe	missense variant	-	NC_000010.11:g.89738984C>T	NCI-TCGA
rs757329358	p.Ala1269Val	missense variant	-	NC_000010.11:g.89738987C>T	ExAC,gnomAD
rs779163740	p.Arg1270Cys	missense variant	-	NC_000010.11:g.89738989C>T	ExAC,TOPMed,gnomAD
rs746139748	p.Arg1270His	missense variant	-	NC_000010.11:g.89738990G>A	ExAC,TOPMed,gnomAD
rs746139748	p.Arg1270Pro	missense variant	-	NC_000010.11:g.89738990G>C	ExAC,TOPMed,gnomAD
rs1389252851	p.Thr1271Ile	missense variant	-	NC_000010.11:g.89738993C>T	TOPMed
rs779935159	p.Gln1272His	missense variant	-	NC_000010.11:g.89738997G>C	ExAC,gnomAD
rs1212993467	p.Asn1273Ser	missense variant	-	NC_000010.11:g.89738999A>G	gnomAD
rs771361517	p.Leu1274Arg	missense variant	-	NC_000010.11:g.89739002T>G	ExAC,TOPMed,gnomAD
rs1458967076	p.Asp1277Gly	missense variant	-	NC_000010.11:g.89739011A>G	gnomAD
rs1231115192	p.Leu1278Arg	missense variant	-	NC_000010.11:g.89739014T>G	TOPMed,gnomAD
rs768678283	p.Leu1278Phe	missense variant	-	NC_000010.11:g.89739013C>T	ExAC,TOPMed,gnomAD
rs768678283	p.Leu1278Val	missense variant	-	NC_000010.11:g.89739013C>G	ExAC,TOPMed,gnomAD
rs372651065	p.Arg1280Ser	missense variant	-	NC_000010.11:g.89739021G>C	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Arg1280Met	missense variant	-	NC_000010.11:g.89739020G>T	NCI-TCGA
COSM5215429	p.Glu1282GlyPheSerTerUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000010.11:g.89739021_89739022insA	NCI-TCGA Cosmic
rs1166413600	p.Glu1283Ter	stop gained	-	NC_000010.11:g.89739028G>T	gnomAD
rs1460408712	p.Asp1284Glu	missense variant	-	NC_000010.11:g.89739033T>A	gnomAD
rs1172101419	p.Tyr1285His	missense variant	-	NC_000010.11:g.89739034T>C	gnomAD
rs1403068630	p.Ala1286Val	missense variant	-	NC_000010.11:g.89739038C>T	gnomAD
rs150394796	p.Asp1287Asn	missense variant	-	NC_000010.11:g.89739040G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1380285102	p.Asp1287Gly	missense variant	-	NC_000010.11:g.89739041A>G	gnomAD
rs267602617	p.Lys1289Thr	missense variant	-	NC_000010.11:g.89739047A>C	TOPMed
rs267602617	p.Lys1289Arg	missense variant	-	NC_000010.11:g.89739047A>G	TOPMed
rs36109527	p.Glu1290Asp	missense variant	-	NC_000010.11:g.89739051G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs529232609	p.Thr1293Ser	missense variant	-	NC_000010.11:g.89739059C>G	1000Genomes,ExAC,gnomAD
rs1250575318	p.Lys1296Glu	missense variant	-	NC_000010.11:g.89739067A>G	gnomAD
rs754382351	p.Lys1296Arg	missense variant	-	NC_000010.11:g.89739068A>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Val1302Ala	missense variant	-	NC_000010.11:g.89739086T>C	NCI-TCGA
rs1196415519	p.Lys1304Glu	missense variant	-	NC_000010.11:g.89739091A>G	TOPMed
COSM1968989	p.Val1306Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89743809T>C	NCI-TCGA Cosmic
COSM1968987	p.Val1306Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89743808G>A	NCI-TCGA Cosmic
rs1439908192	p.Ser1307Cys	missense variant	-	NC_000010.11:g.89743812C>G	TOPMed
rs144377752	p.Arg1310His	missense variant	-	NC_000010.11:g.89743821G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs376129504	p.Arg1310Cys	missense variant	-	NC_000010.11:g.89743820C>T	ESP,ExAC,TOPMed,gnomAD
rs1467271666	p.Asp1311Glu	missense variant	-	NC_000010.11:g.89743825T>A	TOPMed
rs769075368	p.Asp1311Gly	missense variant	-	NC_000010.11:g.89743824A>G	ExAC,gnomAD
rs1174355559	p.Asp1313Gly	missense variant	-	NC_000010.11:g.89743830A>G	gnomAD
rs777106636	p.Lys1314Glu	missense variant	-	NC_000010.11:g.89743832A>G	ExAC,gnomAD
rs943745143	p.Leu1316Pro	missense variant	-	NC_000010.11:g.89743839T>C	TOPMed,gnomAD
rs1300215121	p.Arg1317Thr	missense variant	-	NC_000010.11:g.89743842G>C	gnomAD
rs140968638	p.Ile1320Thr	missense variant	-	NC_000010.11:g.89743851T>C	ESP,ExAC,TOPMed,gnomAD
rs140968638	p.Ile1320Ser	missense variant	-	NC_000010.11:g.89743851T>G	ESP,ExAC,TOPMed,gnomAD
rs1258689947	p.Asn1321Ser	missense variant	-	NC_000010.11:g.89743854A>G	TOPMed
rs1288275610	p.Glu1322Ter	stop gained	-	NC_000010.11:g.89743856G>T	gnomAD
rs543007275	p.Glu1324Asp	missense variant	-	NC_000010.11:g.89743864G>T	1000Genomes,ExAC,TOPMed,gnomAD
rs750426962	p.Glu1324Lys	missense variant	-	NC_000010.11:g.89743862G>A	ExAC,gnomAD
rs1346809088	p.Lys1326Asn	missense variant	-	NC_000010.11:g.89743870G>C	gnomAD
rs751875487	p.Asn1328Lys	missense variant	-	NC_000010.11:g.89743876C>A	ExAC,TOPMed,gnomAD
rs766688685	p.Asn1328Ser	missense variant	-	NC_000010.11:g.89743875A>G	ExAC,TOPMed,gnomAD
rs754819247	p.Ser1331Phe	missense variant	-	NC_000010.11:g.89743884C>T	ExAC,gnomAD
COSM4016547	p.Glu1333Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89743891A>T	NCI-TCGA Cosmic
rs143200257	p.Asp1335Asn	missense variant	-	NC_000010.11:g.89743895G>A	ESP,ExAC,TOPMed,gnomAD
rs143200257	p.Asp1335His	missense variant	-	NC_000010.11:g.89743895G>C	ESP,ExAC,TOPMed,gnomAD
rs1322007971	p.Met1336Thr	missense variant	-	NC_000010.11:g.89743899T>C	TOPMed
rs1232292908	p.Met1336Val	missense variant	-	NC_000010.11:g.89743898A>G	TOPMed
rs777798374	p.Arg1339Gln	missense variant	-	NC_000010.11:g.89743908G>A	ExAC,TOPMed,gnomAD
rs1340241633	p.Arg1339Ter	stop gained	-	NC_000010.11:g.89743907C>T	gnomAD
rs777798374	p.Arg1339Leu	missense variant	-	NC_000010.11:g.89743908G>T	ExAC,TOPMed,gnomAD
rs778333569	p.Glu1346Ala	missense variant	-	NC_000010.11:g.89745900A>C	ExAC,gnomAD
rs1227183188	p.Asn1350Tyr	missense variant	-	NC_000010.11:g.89745911A>T	TOPMed
NCI-TCGA novel	p.Gln1351Glu	missense variant	-	NC_000010.11:g.89745914C>G	NCI-TCGA
rs758003194	p.Glu1354Lys	missense variant	-	NC_000010.11:g.89745923G>A	ExAC,TOPMed,gnomAD
rs1230912039	p.Gln1358Pro	missense variant	-	NC_000010.11:g.89745936A>C	gnomAD
rs748442622	p.Gln1359His	missense variant	-	NC_000010.11:g.89745940G>C	ExAC,TOPMed,gnomAD
rs770237957	p.Tyr1360Cys	missense variant	-	NC_000010.11:g.89745942A>G	ExAC,TOPMed,gnomAD
rs770237957	p.Tyr1360Phe	missense variant	-	NC_000010.11:g.89745942A>T	ExAC,TOPMed,gnomAD
rs1437541031	p.Glu1361Gly	missense variant	-	NC_000010.11:g.89745945A>G	TOPMed,gnomAD
COSM921325	p.Glu1361Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89745946G>T	NCI-TCGA Cosmic
rs1437541031	p.Glu1361Ala	missense variant	-	NC_000010.11:g.89745945A>C	TOPMed,gnomAD
rs774506122	p.Ala1363Gly	missense variant	-	NC_000010.11:g.89745951C>G	ExAC,gnomAD
rs759723028	p.Lys1365Arg	missense variant	-	NC_000010.11:g.89745957A>G	ExAC,TOPMed,gnomAD
rs775560493	p.Asp1366Gly	missense variant	-	NC_000010.11:g.89751346A>G	ExAC,gnomAD
rs775560493	p.Asp1366Val	missense variant	-	NC_000010.11:g.89751346A>T	ExAC,gnomAD
rs1404792604	p.Glu1371Asp	missense variant	-	NC_000010.11:g.89751362G>C	TOPMed
rs370361159	p.Lys1372Glu	missense variant	-	NC_000010.11:g.89751363A>G	1000Genomes,ExAC,gnomAD
rs776366561	p.Met1377Leu	missense variant	-	NC_000010.11:g.89751378A>T	ExAC,gnomAD
rs150940648	p.Met1377Thr	missense variant	-	NC_000010.11:g.89751379T>C	ESP,ExAC,TOPMed,gnomAD
rs765135484	p.Met1377Ile	missense variant	-	NC_000010.11:g.89751380G>A	ExAC,gnomAD
rs750403068	p.Arg1378Leu	missense variant	-	NC_000010.11:g.89751382G>T	ExAC,TOPMed,gnomAD
rs1306111010	p.Arg1378Ter	stop gained	-	NC_000010.11:g.89751381C>T	gnomAD
rs750403068	p.Arg1378Gln	missense variant	-	NC_000010.11:g.89751382G>A	ExAC,TOPMed,gnomAD
rs1237866184	p.Thr1380Ile	missense variant	-	NC_000010.11:g.89751388C>T	TOPMed
COSM1321984	p.Gln1384Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89751399C>G	NCI-TCGA Cosmic
rs1203448954	p.Gln1384Arg	missense variant	-	NC_000010.11:g.89751400A>G	TOPMed,gnomAD
rs751049331	p.Glu1385Lys	missense variant	-	NC_000010.11:g.89751402G>A	ExAC,gnomAD
rs1446391403	p.Glu1385Val	missense variant	-	NC_000010.11:g.89751403A>T	gnomAD
COSM921326	p.Glu1385Gly	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89751403A>G	NCI-TCGA Cosmic
rs780739656	p.Gln1386Arg	missense variant	-	NC_000010.11:g.89751406A>G	ExAC,gnomAD
rs754207898	p.Thr1387Ile	missense variant	-	NC_000010.11:g.89751409C>T	ExAC
rs1172688767	p.Gln1388His	missense variant	-	NC_000010.11:g.89751413G>C	gnomAD
rs375828767	p.Gln1388Arg	missense variant	-	NC_000010.11:g.89751412A>G	ESP,ExAC,TOPMed,gnomAD
rs779556551	p.Val1389Ala	missense variant	-	NC_000010.11:g.89751415T>C	ExAC,gnomAD
COSM921327	p.Val1389Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89751414G>A	NCI-TCGA Cosmic
rs746434011	p.Gln1393Glu	missense variant	-	NC_000010.11:g.89751426C>G	ExAC,gnomAD
rs772469205	p.Val1394Leu	missense variant	-	NC_000010.11:g.89751429G>T	ExAC,gnomAD
rs139452485	p.Lys1398Gln	missense variant	-	NC_000010.11:g.89751441A>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1320548991	p.Lys1398Arg	missense variant	-	NC_000010.11:g.89751442A>G	TOPMed
rs747085766	p.Leu1399Ser	missense variant	-	NC_000010.11:g.89751445T>C	ExAC,gnomAD
rs1289971285	p.Glu1400Gly	missense variant	-	NC_000010.11:g.89751448A>G	TOPMed
rs1369333142	p.Glu1400Gln	missense variant	-	NC_000010.11:g.89751447G>C	gnomAD
rs1440616973	p.Glu1400Asp	missense variant	-	NC_000010.11:g.89751449G>C	gnomAD
rs370697647	p.Val1402Ile	missense variant	-	NC_000010.11:g.89751453G>A	TOPMed
rs370697647	p.Val1402Phe	missense variant	-	NC_000010.11:g.89751453G>T	TOPMed
rs1255364243	p.Leu1405Arg	missense variant	-	NC_000010.11:g.89751463T>G	TOPMed,gnomAD
rs1308160386	p.Ala1406Gly	missense variant	-	NC_000010.11:g.89751466C>G	TOPMed
rs768871419	p.Ala1406Pro	missense variant	-	NC_000010.11:g.89751465G>C	ExAC,gnomAD
rs776884271	p.Thr1407Ala	missense variant	-	NC_000010.11:g.89751468A>G	ExAC,gnomAD
rs761563097	p.Thr1407Ile	missense variant	-	NC_000010.11:g.89751469C>T	ExAC,gnomAD
rs562653854	p.Glu1408Gln	missense variant	-	NC_000010.11:g.89751471G>C	1000Genomes,ExAC,TOPMed,gnomAD
rs1249368634	p.Glu1410Asp	missense variant	-	NC_000010.11:g.89752574A>C	TOPMed,gnomAD
rs1423940708	p.Trp1412Ter	stop gained	-	NC_000010.11:g.89752579G>A	TOPMed,gnomAD
rs149758232	p.Glu1414Lys	missense variant	-	NC_000010.11:g.89752584G>A	ExAC,TOPMed,gnomAD
rs781390219	p.Cys1416Trp	missense variant	-	NC_000010.11:g.89752592C>G	ExAC,gnomAD
rs1171937429	p.Asn1417Asp	missense variant	-	NC_000010.11:g.89752593A>G	gnomAD
rs551478794	p.Asn1417Ser	missense variant	-	NC_000010.11:g.89752594A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs1297867462	p.Thr1421Ile	missense variant	-	NC_000010.11:g.89752606C>T	gnomAD
rs772928845	p.Asn1424Tyr	missense variant	-	NC_000010.11:g.89752614A>T	ExAC,gnomAD
NCI-TCGA novel	p.Asn1424Ser	missense variant	-	NC_000010.11:g.89752615A>G	NCI-TCGA
rs762687954	p.Arg1426Lys	missense variant	-	NC_000010.11:g.89752621G>A	ExAC,gnomAD
rs145617702	p.Arg1426Ser	missense variant	-	NC_000010.11:g.89752622G>T	ESP,ExAC
rs759057746	p.His1431Tyr	missense variant	-	NC_000010.11:g.89752635C>T	ExAC,TOPMed,gnomAD
rs140347341	p.Asn1433Lys	missense variant	-	NC_000010.11:g.89752643C>A	ESP,TOPMed,gnomAD
NCI-TCGA novel	p.Asn1433Asp	missense variant	-	NC_000010.11:g.89752641A>G	NCI-TCGA
rs145399222	p.Val1437Leu	missense variant	-	NC_000010.11:g.89752653G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
COSM921328	p.Val1437Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89752653G>A	NCI-TCGA Cosmic
rs775151933	p.Lys1440Gln	missense variant	-	NC_000010.11:g.89752662A>C	ExAC,gnomAD
rs1250455536	p.Thr1442Ala	missense variant	-	NC_000010.11:g.89752668A>G	gnomAD
rs763870025	p.Asn1443Asp	missense variant	-	NC_000010.11:g.89752671A>G	ExAC,TOPMed,gnomAD
rs1212522045	p.Gln1445Leu	missense variant	-	NC_000010.11:g.89752678A>T	gnomAD
rs1254794348	p.Asp1446Val	missense variant	-	NC_000010.11:g.89752681A>T	gnomAD
rs181525895	p.Leu1448Ile	missense variant	-	NC_000010.11:g.89752686T>A	1000Genomes,ExAC,gnomAD
rs374333263	p.Gln1449Ter	stop gained	-	NC_000010.11:g.89752689C>T	ESP,ExAC,TOPMed,gnomAD
rs374333263	p.Gln1449Glu	missense variant	-	NC_000010.11:g.89752689C>G	ESP,ExAC,TOPMed,gnomAD
rs1371544083	p.Glu1452Gln	missense variant	-	NC_000010.11:g.89754524G>C	gnomAD
rs751627130	p.LysTyrAsn1454LysTerUnk	stop gained	-	NC_000010.11:g.89754535_89754536del	ExAC,TOPMed,gnomAD
rs1223945190	p.Asn1456Ser	missense variant	-	NC_000010.11:g.89754537A>G	gnomAD
rs1328374349	p.Asn1456Asp	missense variant	-	NC_000010.11:g.89754536A>G	TOPMed
NCI-TCGA novel	p.Ala1457Ser	missense variant	-	NC_000010.11:g.89754539G>T	NCI-TCGA
rs372851514	p.Asp1458Gly	missense variant	-	NC_000010.11:g.89754543A>G	ESP,ExAC,TOPMed,gnomAD
rs1480730059	p.Asp1458Asn	missense variant	-	NC_000010.11:g.89754542G>A	gnomAD
rs1162022656	p.Arg1459Lys	missense variant	-	NC_000010.11:g.89754546G>A	TOPMed
COSM4696003	p.Lys1460Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89754550G>T	NCI-TCGA Cosmic
NCI-TCGA novel	p.Lys1460Glu	missense variant	-	NC_000010.11:g.89754548A>G	NCI-TCGA
rs1470146329	p.Lys1461Thr	missense variant	-	NC_000010.11:g.89754552A>C	gnomAD
rs1386359342	p.Lys1461Glu	missense variant	-	NC_000010.11:g.89754551A>G	TOPMed
rs775618151	p.Trp1462Ter	stop gained	-	NC_000010.11:g.89754556G>A	ExAC,gnomAD
rs1470650025	p.Glu1464Gly	missense variant	-	NC_000010.11:g.89754561A>G	gnomAD
rs375746203	p.Glu1465Gly	missense variant	-	NC_000010.11:g.89754564A>G	ESP,ExAC,TOPMed,gnomAD
rs768347589	p.Lys1466Glu	missense variant	-	NC_000010.11:g.89754566A>G	ExAC,TOPMed,gnomAD
rs776330910	p.Lys1466Arg	missense variant	-	NC_000010.11:g.89754567A>G	ExAC,gnomAD
rs761315179	p.Met1467Leu	missense variant	-	NC_000010.11:g.89754569A>C	ExAC,gnomAD
NCI-TCGA novel	p.Met1467Ter	frameshift	-	NC_000010.11:g.89754564A>-	NCI-TCGA
rs1462911101	p.Met1468Val	missense variant	-	NC_000010.11:g.89754572A>G	gnomAD
rs769492969	p.Leu1469Val	missense variant	-	NC_000010.11:g.89754575C>G	ExAC
rs759915981	p.Thr1471Pro	missense variant	-	NC_000010.11:g.89754581A>C	ExAC,gnomAD
rs369170052	p.Gln1472Glu	missense variant	-	NC_000010.11:g.89754584C>G	ESP,ExAC,TOPMed,gnomAD
rs372720193	p.Gln1472His	missense variant	-	NC_000010.11:g.89754586A>T	ESP,ExAC,TOPMed,gnomAD
rs753954878	p.Ala1473Val	missense variant	-	NC_000010.11:g.89754588C>T	ExAC,TOPMed,gnomAD
rs764140726	p.Ala1473Thr	missense variant	-	NC_000010.11:g.89754587G>A	ExAC,TOPMed,gnomAD
rs1024977291	p.Lys1474Glu	missense variant	-	NC_000010.11:g.89754590A>G	TOPMed,gnomAD
rs1272964199	p.Ala1476Thr	missense variant	-	NC_000010.11:g.89754596G>A	gnomAD
rs1356535476	p.Asn1478Thr	missense variant	-	NC_000010.11:g.89754603A>C	TOPMed,gnomAD
rs757378200	p.Ile1479Thr	missense variant	-	NC_000010.11:g.89754606T>C	ExAC,TOPMed,gnomAD
rs1443182066	p.Ile1479Val	missense variant	-	NC_000010.11:g.89754605A>G	gnomAD
rs757378200	p.Ile1479Lys	missense variant	-	NC_000010.11:g.89754606T>A	ExAC,TOPMed,gnomAD
rs750217355	p.Arg1480Gln	missense variant	-	NC_000010.11:g.89754609G>A	ExAC,TOPMed,gnomAD
rs376548512	p.Arg1480Ter	stop gained	-	NC_000010.11:g.89754608C>T	ESP,ExAC,gnomAD
rs574289755	p.Asn1481Ser	missense variant	-	NC_000010.11:g.89754612A>G	1000Genomes,ExAC,gnomAD
rs1469736437	p.Asn1481Tyr	missense variant	-	NC_000010.11:g.89754611A>T	TOPMed,gnomAD
rs1420048982	p.Met1484Thr	missense variant	-	NC_000010.11:g.89754621T>C	gnomAD
rs979748115	p.Lys1486Asn	missense variant	-	NC_000010.11:g.89754628A>T	TOPMed
rs926935231	p.Tyr1487Phe	missense variant	-	NC_000010.11:g.89754630A>T	TOPMed
rs369338310	p.Tyr1487Ter	stop gained	-	NC_000010.11:g.89754631T>G	ESP,ExAC,TOPMed,gnomAD
rs1389830656	p.Ala1488Thr	missense variant	-	NC_000010.11:g.89754632G>A	gnomAD
rs1293078823	p.Asp1490Val	missense variant	-	NC_000010.11:g.89754639A>T	gnomAD
rs1330526853	p.Glu1492Gln	missense variant	-	NC_000010.11:g.89754644G>C	gnomAD
rs768653134	p.Arg1493Cys	missense variant	-	NC_000010.11:g.89754647C>T	ExAC,TOPMed,gnomAD
rs763688811	p.Arg1493His	missense variant	-	NC_000010.11:g.89754648G>A	TOPMed
rs755841488	p.Phe1495LeuPheSerTerUnkUnk	frameshift	-	NC_000010.11:g.89754649T>-	NCI-TCGA,NCI-TCGA Cosmic
rs1304082399	p.Phe1495Leu	missense variant	-	NC_000010.11:g.89754655T>A	gnomAD
rs779958420	p.Lys1496Ter	frameshift	-	NC_000010.11:g.89754648_89754649insT	NCI-TCGA
rs1341306872	p.Gln1497Glu	missense variant	-	NC_000010.11:g.89754659C>G	gnomAD
rs1312985982	p.Gln1497Pro	missense variant	-	NC_000010.11:g.89754660A>C	gnomAD
rs191471368	p.Asn1499Ser	missense variant	-	NC_000010.11:g.89754666A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs747725874	p.Glu1500Lys	missense variant	-	NC_000010.11:g.89754668G>A	ExAC,TOPMed,gnomAD
rs1433457970	p.Glu1502Lys	missense variant	-	NC_000010.11:g.89758706G>A	gnomAD
rs751407460	p.Leu1504Pro	missense variant	-	NC_000010.11:g.89758713T>C	ExAC,TOPMed,gnomAD
rs373622507	p.Thr1505Ala	missense variant	-	NC_000010.11:g.89758715A>G	ESP,ExAC,TOPMed,gnomAD
rs781212813	p.Ala1506Ser	missense variant	-	NC_000010.11:g.89758718G>T	ExAC,gnomAD
rs747590327	p.Gln1507His	missense variant	-	NC_000010.11:g.89758723G>T	ExAC,gnomAD
rs1263237328	p.Asp1512Gly	missense variant	-	NC_000010.11:g.89758737A>G	gnomAD
rs769390762	p.Ser1513Gly	missense variant	-	NC_000010.11:g.89758739A>G	ExAC,TOPMed,gnomAD
rs543186692	p.Leu1515Phe	missense variant	-	NC_000010.11:g.89758745C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs543186692	p.Leu1515Val	missense variant	-	NC_000010.11:g.89758745C>G	1000Genomes,ExAC,TOPMed,gnomAD
rs749002204	p.Arg1519Gln	missense variant	-	NC_000010.11:g.89758758G>A	ExAC,TOPMed,gnomAD
rs1195171569	p.Glu1520Ala	missense variant	-	NC_000010.11:g.89758761A>C	gnomAD
rs377664920	p.Glu1520Gln	missense variant	-	NC_000010.11:g.89758760G>C	ESP,TOPMed
rs1254215373	p.Glu1521Gly	missense variant	-	NC_000010.11:g.89758764A>G	TOPMed,gnomAD
rs1193663750	p.Glu1521Gln	missense variant	-	NC_000010.11:g.89758763G>C	TOPMed,gnomAD
rs770586475	p.Arg1522Gln	missense variant	-	NC_000010.11:g.89758767G>A	ExAC,gnomAD
rs1249853998	p.Ala1527Val	missense variant	-	NC_000010.11:g.89758782C>T	TOPMed
rs1396486267	p.Glu1530Lys	missense variant	-	NC_000010.11:g.89758790G>A	gnomAD
rs747420235	p.Gln1532Glu	missense variant	-	NC_000010.11:g.89758796C>G	ExAC,TOPMed,gnomAD
rs769017488	p.Leu1536Pro	missense variant	-	NC_000010.11:g.89758809T>C	ExAC,gnomAD
rs777231047	p.Ile1537Leu	missense variant	-	NC_000010.11:g.89758811A>C	ExAC,TOPMed,gnomAD
rs1422085097	p.Asn1540Ser	missense variant	-	NC_000010.11:g.89758821A>G	gnomAD
rs984746275	p.Val1541Ile	missense variant	-	NC_000010.11:g.89758823G>A	TOPMed
rs1442063256	p.Gln1542Ter	stop gained	-	NC_000010.11:g.89758826C>T	gnomAD
rs566396878	p.Lys1543Arg	missense variant	-	NC_000010.11:g.89758830A>G	gnomAD
NCI-TCGA novel	p.Asp1544GluPheSerTerUnk	frameshift	-	NC_000010.11:g.89758833_89758839ATAATGA>-	NCI-TCGA
rs1232743418	p.Asn1545Lys	missense variant	-	NC_000010.11:g.89758837T>G	gnomAD
NCI-TCGA novel	p.Glu1546Asp	missense variant	-	NC_000010.11:g.89758840A>C	NCI-TCGA
NCI-TCGA novel	p.Glu1546Lys	missense variant	-	NC_000010.11:g.89758838G>A	NCI-TCGA
NCI-TCGA novel	p.Ile1547Met	missense variant	-	NC_000010.11:g.89758843T>G	NCI-TCGA
rs761795134	p.Arg1552Ser	missense variant	-	NC_000010.11:g.89758858G>T	ExAC
NCI-TCGA novel	p.Arg1552GlyPheSerTerUnk	frameshift	-	NC_000010.11:g.89758852A>-	NCI-TCGA
rs1036171550	p.Ile1554Met	missense variant	-	NC_000010.11:g.89758864A>G	gnomAD
rs146822498	p.Ile1554Thr	missense variant	-	NC_000010.11:g.89758863T>C	ESP,ExAC,TOPMed,gnomAD
COSM3441440	p.Ser1558Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89758875C>T	NCI-TCGA Cosmic
rs1254606678	p.Ser1558Cys	missense variant	-	NC_000010.11:g.89758875C>G	gnomAD
rs34785987	p.Ile1560Thr	missense variant	-	NC_000010.11:g.89758881T>C	1000Genomes,ESP,TOPMed
rs748629781	p.Thr1562Ile	missense variant	-	NC_000010.11:g.89760530C>T	ExAC,TOPMed,gnomAD
rs777360606	p.Gln1563Arg	missense variant	-	NC_000010.11:g.89760533A>G	ExAC,gnomAD
rs777360606	p.Gln1563Pro	missense variant	-	NC_000010.11:g.89760533A>C	ExAC,gnomAD
rs763150244	p.Ile1564Thr	missense variant	-	NC_000010.11:g.89760536T>C	ExAC,gnomAD
rs773387834	p.Ile1564Val	missense variant	-	NC_000010.11:g.89760535A>G	ExAC,gnomAD
rs774674676	p.Met1565Val	missense variant	-	NC_000010.11:g.89760538A>G	ExAC,gnomAD
rs767407693	p.Asp1566Gly	missense variant	-	NC_000010.11:g.89760542A>G	ExAC,gnomAD
rs200556371	p.Asp1566Tyr	missense variant	-	NC_000010.11:g.89760541G>T	1000Genomes,ExAC,gnomAD
rs143700194	p.Ile1567Val	missense variant	-	NC_000010.11:g.89760544A>G	ESP,ExAC,gnomAD
rs1243751032	p.Lys1570Gln	missense variant	-	NC_000010.11:g.89760553A>C	gnomAD
rs753320982	p.Arg1571His	missense variant	-	NC_000010.11:g.89760557G>A	ExAC,TOPMed,gnomAD
rs764038459	p.Arg1571Cys	missense variant	-	NC_000010.11:g.89760556C>T	ExAC,TOPMed,gnomAD
rs756795355	p.Ser1574Pro	missense variant	-	NC_000010.11:g.89760565T>C	ExAC,TOPMed,gnomAD
rs778528212	p.Ser1574Leu	missense variant	-	NC_000010.11:g.89760566C>T	ExAC,gnomAD
NCI-TCGA novel	p.Asp1576Tyr	missense variant	-	NC_000010.11:g.89760571G>T	NCI-TCGA
rs1485711702	p.Pro1577Arg	missense variant	-	NC_000010.11:g.89760575C>G	gnomAD
rs371471387	p.Asp1578Gly	missense variant	-	NC_000010.11:g.89760578A>G	ESP,ExAC,TOPMed
rs1190772602	p.Asp1578Glu	missense variant	-	NC_000010.11:g.89760579C>G	gnomAD
rs567515372	p.Lys1579Gln	missense variant	-	NC_000010.11:g.89760580A>C	1000Genomes
rs1400076532	p.Leu1580Phe	missense variant	-	NC_000010.11:g.89760583C>T	TOPMed
rs1171719423	p.Thr1582Ile	missense variant	-	NC_000010.11:g.89760590C>T	TOPMed
NCI-TCGA novel	p.Leu1585Pro	missense variant	-	NC_000010.11:g.89760599T>C	NCI-TCGA
rs748491739	p.Ser1586Leu	missense variant	-	NC_000010.11:g.89760602C>T	ExAC,TOPMed,gnomAD
rs117258675	p.Phe1589Tyr	missense variant	-	NC_000010.11:g.89760611T>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Glu1590Val	missense variant	-	NC_000010.11:g.89760614A>T	NCI-TCGA
rs749349671	p.Asn1594Lys	missense variant	-	NC_000010.11:g.89760627T>G	ExAC,TOPMed,gnomAD
rs771205502	p.Ile1596Leu	missense variant	-	NC_000010.11:g.89760631A>C	ExAC,gnomAD
rs768494378	p.Asp1598Val	missense variant	-	NC_000010.11:g.89762639A>T	ExAC,gnomAD
rs768494378	p.Asp1598Gly	missense variant	-	NC_000010.11:g.89762639A>G	ExAC,gnomAD
rs952018066	p.Val1601Ile	missense variant	-	NC_000010.11:g.89762647G>A	TOPMed,gnomAD
rs140933422	p.Val1601Ala	missense variant	-	NC_000010.11:g.89762648T>C	ESP,ExAC,TOPMed,gnomAD
rs765115896	p.Leu1603Phe	missense variant	-	NC_000010.11:g.89762653C>T	ExAC,gnomAD
rs764084518	p.Asp1604Val	missense variant	-	NC_000010.11:g.89762657A>T	ExAC,TOPMed,gnomAD
rs1253967842	p.Cys1606Trp	missense variant	-	NC_000010.11:g.89762664T>G	TOPMed,gnomAD
rs1269940217	p.Glu1611Lys	missense variant	-	NC_000010.11:g.89762677G>A	TOPMed
rs1455756231	p.Asn1612Asp	missense variant	-	NC_000010.11:g.89762680A>G	gnomAD
rs1424629660	p.Gln1614His	missense variant	-	NC_000010.11:g.89762688A>C	gnomAD
rs751324087	p.Gln1614Arg	missense variant	-	NC_000010.11:g.89762687A>G	ExAC,gnomAD
rs1159808784	p.Arg1617Ter	stop gained	-	NC_000010.11:g.89762695C>T	TOPMed,gnomAD
rs756536781	p.Arg1617Gln	missense variant	-	NC_000010.11:g.89762696G>A	ExAC,TOPMed,gnomAD
rs982597098	p.Pro1619Arg	missense variant	-	NC_000010.11:g.89762702C>G	gnomAD
COSM4929221	p.Ile1625Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89762719A>G	NCI-TCGA Cosmic
rs142595855	p.Gln1626His	missense variant	-	NC_000010.11:g.89762724A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1394878786	p.Gln1631Ter	stop gained	-	NC_000010.11:g.89762737C>T	gnomAD
rs1272716608	p.Pro1632Ala	missense variant	-	NC_000010.11:g.89762740C>G	gnomAD
rs1272716608	p.Pro1632Ser	missense variant	-	NC_000010.11:g.89762740C>T	gnomAD
rs757801434	p.Asn1633Asp	missense variant	-	NC_000010.11:g.89762743A>G	ExAC,gnomAD
rs984762974	p.Asn1633Ile	missense variant	-	NC_000010.11:g.89762744A>T	TOPMed,gnomAD
rs984762974	p.Asn1633Ser	missense variant	-	NC_000010.11:g.89762744A>G	TOPMed,gnomAD
rs373911396	p.Lys1634Glu	missense variant	-	NC_000010.11:g.89762746A>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys1634Arg	missense variant	-	NC_000010.11:g.89762747A>G	NCI-TCGA
rs758470528	p.Met1635Arg	missense variant	-	NC_000010.11:g.89762750T>G	ExAC,TOPMed,gnomAD
rs745927589	p.Met1635Val	missense variant	-	NC_000010.11:g.89762749A>G	ExAC,gnomAD
rs758470528	p.Met1635Thr	missense variant	-	NC_000010.11:g.89762750T>C	ExAC,TOPMed,gnomAD
rs201324774	p.Ala1636Ser	missense variant	-	NC_000010.11:g.89762752G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs201324774	p.Ala1636Thr	missense variant	-	NC_000010.11:g.89762752G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs574555372	p.His1639Gln	missense variant	-	NC_000010.11:g.89762763C>G	1000Genomes,ExAC,gnomAD
rs757096168	p.Pro1640Ser	missense variant	-	NC_000010.11:g.89762764C>T	ExAC,TOPMed,gnomAD
rs368820868	p.Pro1640Arg	missense variant	-	NC_000010.11:g.89762765C>G	ESP,ExAC,TOPMed,gnomAD
rs773064916	p.Gly1641Cys	missense variant	-	NC_000010.11:g.89762767G>T	ExAC,TOPMed,gnomAD
rs1409789695	p.Cys1642Arg	missense variant	-	NC_000010.11:g.89762770T>C	gnomAD
rs1471579363	p.Thr1644Pro	missense variant	-	NC_000010.11:g.89762776A>C	TOPMed,gnomAD
rs1471579363	p.Thr1644Ala	missense variant	-	NC_000010.11:g.89762776A>G	TOPMed,gnomAD
rs372743403	p.Thr1644Arg	missense variant	-	NC_000010.11:g.89762777C>G	ESP,TOPMed
rs1201618668	p.Pro1645Leu	missense variant	-	NC_000010.11:g.89762780C>T	TOPMed
rs34354493	p.Lys1649Glu	missense variant	-	NC_000010.11:g.89762791A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1202215706	p.Lys1649Asn	missense variant	-	NC_000010.11:g.89762793G>T	TOPMed
rs1348969834	p.Ile1650Asn	missense variant	-	NC_000010.11:g.89762795T>A	TOPMed,gnomAD
rs143235231	p.Lys1652Arg	missense variant	-	NC_000010.11:g.89762801A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs759202813	p.Ala1653Pro	missense variant	-	NC_000010.11:g.89762803G>C	ExAC,gnomAD
NCI-TCGA novel	p.Ala1653GlyPheSerTerUnk	stop gained	-	NC_000010.11:g.89762803_89762804insGAGGAGGCTGAGAT	NCI-TCGA
rs376655083	p.Arg1654Trp	missense variant	-	NC_000010.11:g.89762806C>T	ESP,ExAC,TOPMed,gnomAD
rs115570983	p.Arg1654Gln	missense variant	-	NC_000010.11:g.89762807G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs757599461	p.Ser1658Asn	missense variant	-	NC_000010.11:g.89762819G>A	ExAC,gnomAD
rs765766934	p.Asn1659Asp	missense variant	-	NC_000010.11:g.89762821A>G	ExAC,gnomAD
rs750945434	p.Asn1659Ser	missense variant	-	NC_000010.11:g.89762822A>G	ExAC,gnomAD
rs1452489521	p.Glu1660Lys	missense variant	-	NC_000010.11:g.89762824G>A	TOPMed
rs1482768910	p.Met1661Val	missense variant	-	NC_000010.11:g.89762827A>G	TOPMed,gnomAD
rs1224912389	p.Met1661Ile	missense variant	-	NC_000010.11:g.89762829G>A	gnomAD
rs1213187988	p.Asp1664Gly	missense variant	-	NC_000010.11:g.89768291A>G	TOPMed
rs1447403733	p.Leu1665Val	missense variant	-	NC_000010.11:g.89768293T>G	gnomAD
rs1210393218	p.Val1666Ala	missense variant	-	NC_000010.11:g.89768297T>C	gnomAD
rs751615287	p.Lys1667Asn	missense variant	-	NC_000010.11:g.89768301A>C	ExAC,TOPMed,gnomAD
rs755091040	p.Asn1670Lys	missense variant	-	NC_000010.11:g.89768310T>G	ExAC,gnomAD
rs1378929667	p.Lys1671Gln	missense variant	-	NC_000010.11:g.89768311A>C	gnomAD
rs781388195	p.Lys1671Arg	missense variant	-	NC_000010.11:g.89768312A>G	ExAC,gnomAD
rs376717572	p.Lys1672Arg	missense variant	-	NC_000010.11:g.89768315A>G	ESP,ExAC,gnomAD
rs1468953564	p.Thr1675Ala	missense variant	-	NC_000010.11:g.89768323A>G	TOPMed
COSM4898152	p.Pro1676Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89768326C>T	NCI-TCGA Cosmic
rs201898545	p.Arg1677Thr	missense variant	-	NC_000010.11:g.89768330G>C	ExAC,TOPMed,gnomAD
rs201898545	p.Arg1677Ile	missense variant	-	NC_000010.11:g.89768330G>T	ExAC,TOPMed,gnomAD
rs1015551557	p.Arg1677Gly	missense variant	-	NC_000010.11:g.89768329A>G	TOPMed
NCI-TCGA novel	p.Thr1678Ser	missense variant	-	NC_000010.11:g.89768333C>G	NCI-TCGA
NCI-TCGA novel	p.Leu1680Phe	missense variant	-	NC_000010.11:g.89768340G>T	NCI-TCGA
rs775151632	p.Lys1681Asn	missense variant	-	NC_000010.11:g.89768343A>C	ExAC
rs1373765390	p.Lys1681Arg	missense variant	-	NC_000010.11:g.89768342A>G	TOPMed,gnomAD
rs373257085	p.Pro1683Arg	missense variant	-	NC_000010.11:g.89768348C>G	ESP,ExAC,TOPMed,gnomAD
COSM3441442	p.Pro1683Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89768347C>T	NCI-TCGA Cosmic
rs1187005890	p.Pro1683Ala	missense variant	-	NC_000010.11:g.89768347C>G	TOPMed
rs768384923	p.Ile1684Val	missense variant	-	NC_000010.11:g.89768350A>G	ExAC,gnomAD
rs1280171802	p.Ser1685Ter	stop gained	-	NC_000010.11:g.89768354C>A	gnomAD
rs773398410	p.Asp1686Tyr	missense variant	-	NC_000010.11:g.89768356G>T	ExAC,gnomAD
rs763423034	p.Asp1687Gly	missense variant	-	NC_000010.11:g.89768360A>G	ExAC,TOPMed,gnomAD
rs1464272867	p.Asn1689Asp	missense variant	-	NC_000010.11:g.89768365A>G	gnomAD
COSM3791023	p.Ser1690Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89768369C>T	NCI-TCGA Cosmic
rs1197571196	p.Lys1693Arg	missense variant	-	NC_000010.11:g.89768378A>G	gnomAD
NCI-TCGA novel	p.Glu1695GlyPheSerTerUnkUnk	frameshift	-	NC_000010.11:g.89768376_89768377insA	NCI-TCGA
NCI-TCGA novel	p.Val1698Ile	missense variant	-	NC_000010.11:g.89768738G>A	NCI-TCGA
rs763223975	p.Ala1699Val	missense variant	-	NC_000010.11:g.89768742C>T	ExAC,gnomAD
rs546317045	p.Ile1700Met	missense variant	-	NC_000010.11:g.89768746A>G	1000Genomes,ExAC,gnomAD
COSM3807959	p.Ile1700Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89768745T>A	NCI-TCGA Cosmic
rs1396472277	p.Ile1700Val	missense variant	-	NC_000010.11:g.89768744A>G	gnomAD
rs12413968	p.Arg1701Cys	missense variant	-	NC_000010.11:g.89768747C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs759971040	p.Arg1701His	missense variant	-	NC_000010.11:g.89768748G>A	ExAC,TOPMed,gnomAD
rs764195712	p.Lys1705Gln	missense variant	-	NC_000010.11:g.89768759A>C	ExAC,gnomAD
rs764195712	p.Lys1705Glu	missense variant	-	NC_000010.11:g.89768759A>G	ExAC,gnomAD
COSM466069	p.Lys1705Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89768760A>C	NCI-TCGA Cosmic
rs754143638	p.Lys1706Glu	missense variant	-	NC_000010.11:g.89768762A>G	ExAC,TOPMed,gnomAD
rs757562183	p.Thr1707Ala	missense variant	-	NC_000010.11:g.89768765A>G	ExAC,gnomAD
rs1031277703	p.Ser1709Tyr	missense variant	-	NC_000010.11:g.89768772C>A	TOPMed
rs148623215	p.Arg1711Trp	missense variant	-	NC_000010.11:g.89768777C>T	ESP,ExAC,TOPMed,gnomAD
rs758361205	p.Arg1711Gln	missense variant	-	NC_000010.11:g.89768778G>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Arg1711Leu	missense variant	-	NC_000010.11:g.89768778G>T	NCI-TCGA
rs1168065833	p.Gln1713Pro	missense variant	-	NC_000010.11:g.89768784A>C	gnomAD
rs1168065833	p.Gln1713Arg	missense variant	-	NC_000010.11:g.89768784A>G	gnomAD
rs1428026468	p.Gln1713Glu	missense variant	-	NC_000010.11:g.89768783C>G	gnomAD
rs780086166	p.Ala1714Pro	missense variant	-	NC_000010.11:g.89768786G>C	ExAC,TOPMed,gnomAD
rs746470352	p.Ser1715Ala	missense variant	-	NC_000010.11:g.89768789T>G	ExAC,gnomAD
rs142040916	p.Ile1716Thr	missense variant	-	NC_000010.11:g.89768793T>C	ESP,ExAC,gnomAD
rs1260281879	p.Ile1716Val	missense variant	-	NC_000010.11:g.89768792A>G	TOPMed
COSM921334	p.Ile1716Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89768794A>G	NCI-TCGA Cosmic
rs528668353	p.Ile1717Met	missense variant	-	NC_000010.11:g.89768797T>G	1000Genomes
rs780696522	p.Val1719Ala	missense variant	-	NC_000010.11:g.89768802T>C	ExAC,gnomAD
rs895383251	p.Val1719Ile	missense variant	-	NC_000010.11:g.89768801G>A	TOPMed
NCI-TCGA novel	p.Asn1720Lys	missense variant	-	NC_000010.11:g.89768806C>A	NCI-TCGA
rs1298011216	p.Thr1723Ser	missense variant	-	NC_000010.11:g.89768813A>T	gnomAD
rs1296232866	p.Glu1727Lys	missense variant	-	NC_000010.11:g.89768825G>A	gnomAD
rs1442268474	p.Thr1729Ile	missense variant	-	NC_000010.11:g.89768832C>T	gnomAD
rs771181894	p.Thr1729Ala	missense variant	-	NC_000010.11:g.89768831A>G	TOPMed,gnomAD
NCI-TCGA novel	p.Gln1731His	missense variant	-	NC_000010.11:g.89768839G>T	NCI-TCGA
COSM4016549	p.Lys1732Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89768840A>C	NCI-TCGA Cosmic
rs921186546	p.Asp1735Gly	missense variant	-	NC_000010.11:g.89768850A>G	TOPMed
rs772549830	p.Gln1738Glu	missense variant	-	NC_000010.11:g.89768858C>G	ExAC,gnomAD
rs776108059	p.His1739Arg	missense variant	-	NC_000010.11:g.89768862A>G	ExAC,gnomAD
rs1250239697	p.His1739Tyr	missense variant	-	NC_000010.11:g.89768861C>T	gnomAD
rs1188158080	p.Pro1741Leu	missense variant	-	NC_000010.11:g.89768868C>T	gnomAD
rs1322714331	p.Ile1743Val	missense variant	-	NC_000010.11:g.89768873A>G	TOPMed
rs1325054690	p.Gln1745Leu	missense variant	-	NC_000010.11:g.89768880A>T	gnomAD
rs764172829	p.Ser1746Ala	missense variant	-	NC_000010.11:g.89768882T>G	ExAC
rs370718991	p.Ser1746Leu	missense variant	-	NC_000010.11:g.89768883C>T	ESP,ExAC,TOPMed,gnomAD
rs146273081	p.Lys1747Glu	missense variant	-	NC_000010.11:g.89768885A>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys1747Asn	missense variant	-	NC_000010.11:g.89768887A>T	NCI-TCGA
rs769072412	p.Lys1750Asn	missense variant	-	NC_000010.11:g.89772696G>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys1750Gln	missense variant	-	NC_000010.11:g.89772694A>C	NCI-TCGA
rs1028258912	p.Ile1751Val	missense variant	-	NC_000010.11:g.89772697A>G	gnomAD
rs201409025	p.Ile1751Met	missense variant	-	NC_000010.11:g.89772699A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1367562995	p.Ile1752Val	missense variant	-	NC_000010.11:g.89772700A>G	gnomAD
rs1187927154	p.Ile1752Thr	missense variant	-	NC_000010.11:g.89772701T>C	TOPMed
rs573851095	p.Thr1754Ala	missense variant	-	NC_000010.11:g.89772706A>G	ExAC,gnomAD
rs1005747354	p.Met1755Leu	missense variant	-	NC_000010.11:g.89772709A>T	TOPMed
rs1366281915	p.Ser1756Asn	missense variant	-	NC_000010.11:g.89772713G>A	gnomAD
rs150319847	p.Ser1756Gly	missense variant	-	NC_000010.11:g.89772712A>G	1000Genomes,ExAC,gnomAD
rs762828334	p.Ser1757Pro	missense variant	-	NC_000010.11:g.89772715T>C	ExAC,TOPMed,gnomAD
rs1271964118	p.Ser1757Phe	missense variant	-	NC_000010.11:g.89772716C>T	TOPMed
rs1327571015	p.Lys1759Glu	missense variant	-	NC_000010.11:g.89772721A>G	gnomAD
rs1196191921	p.Leu1760His	missense variant	-	NC_000010.11:g.89772725T>A	TOPMed
rs751317141	p.Ser1761Ala	missense variant	-	NC_000010.11:g.89772727T>G	ExAC,gnomAD
rs1291339298	p.Asn1762His	missense variant	-	NC_000010.11:g.89772730A>C	TOPMed
rs767379483	p.Glu1764Gly	missense variant	-	NC_000010.11:g.89772737A>G	ExAC,gnomAD
rs1232665100	p.Ala1765Gly	missense variant	-	NC_000010.11:g.89772740C>G	TOPMed
rs139378013	p.Ser1766Gly	missense variant	-	NC_000010.11:g.89772742A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs777401726	p.Lys1767Thr	missense variant	-	NC_000010.11:g.89772746A>C	ExAC
rs1253849494	p.Asn1769Ser	missense variant	-	NC_000010.11:g.89772752A>G	gnomAD
rs368329596	p.Gln1772Leu	missense variant	-	NC_000010.11:g.89772761A>T	ESP,ExAC,TOPMed,gnomAD
rs1286037544	p.Gln1772Glu	missense variant	-	NC_000010.11:g.89772760C>G	TOPMed
rs780423330	p.Pro1773Ser	missense variant	-	NC_000010.11:g.89772763C>T	ExAC,gnomAD
rs1354193806	p.Pro1773Arg	missense variant	-	NC_000010.11:g.89772764C>G	TOPMed
rs769182388	p.Arg1775Gln	missense variant	-	NC_000010.11:g.89772770G>A	ExAC,TOPMed,gnomAD
rs781774112	p.Ala1776Pro	missense variant	-	NC_000010.11:g.89772772G>C	ExAC,gnomAD
COSM1349734	p.Lys1777Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89772776A>G	NCI-TCGA Cosmic
rs146495295	p.Arg1778Gln	missense variant	-	NC_000010.11:g.89772779G>A	ESP,ExAC,TOPMed,gnomAD
rs1009246322	p.Arg1778Trp	missense variant	-	NC_000010.11:g.89772778C>T	TOPMed,gnomAD
rs770056634	p.Leu1780Ser	missense variant	-	NC_000010.11:g.89772785T>C	ExAC,gnomAD
rs1285160504	p.Tyr1781Phe	missense variant	-	NC_000010.11:g.89772788A>T	gnomAD
rs773439094	p.Tyr1781Asn	missense variant	-	NC_000010.11:g.89772787T>A	ExAC,TOPMed,gnomAD
rs1285160504	p.Tyr1781Cys	missense variant	-	NC_000010.11:g.89772788A>G	gnomAD
rs773439094	p.Tyr1781His	missense variant	-	NC_000010.11:g.89772787T>C	ExAC,TOPMed,gnomAD
rs763169833	p.Thr1782Ala	missense variant	-	NC_000010.11:g.89772790A>G	ExAC,gnomAD
rs771091686	p.Pro1788Thr	missense variant	-	NC_000010.11:g.89772808C>A	ExAC,gnomAD
rs771091686	p.Pro1788Ser	missense variant	-	NC_000010.11:g.89772808C>T	ExAC,gnomAD
rs774148398	p.Pro1788Leu	missense variant	-	NC_000010.11:g.89772809C>T	ExAC,gnomAD
rs3758390	p.Ile1789Val	missense variant	-	NC_000010.11:g.89772811A>G	ExAC,TOPMed,gnomAD
rs954123145	p.Ile1789Thr	missense variant	-	NC_000010.11:g.89772812T>C	TOPMed
rs140984225	p.Asp1790Val	missense variant	-	NC_000010.11:g.89772815A>T	ESP
rs1180920788	p.Ile1791Thr	missense variant	-	NC_000010.11:g.89772818T>C	gnomAD
rs1180920788	p.Ile1791Lys	missense variant	-	NC_000010.11:g.89772818T>A	gnomAD
rs150021584	p.Ile1791Val	missense variant	-	NC_000010.11:g.89772817A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs752701199	p.Ile1791Met	missense variant	-	NC_000010.11:g.89772819A>G	ExAC,TOPMed,gnomAD
rs201320327	p.Gly1793Ser	missense variant	-	NC_000010.11:g.89772823G>A	1000Genomes
NCI-TCGA novel	p.Gly1793Asp	missense variant	-	NC_000010.11:g.89772824G>A	NCI-TCGA
rs145242589	p.Val1795Met	missense variant	-	NC_000010.11:g.89772829G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs571567275	p.Val1795Gly	missense variant	-	NC_000010.11:g.89772830T>G	1000Genomes,ExAC,gnomAD
rs376533308	p.Gln1800Arg	missense variant	-	NC_000010.11:g.89773984A>G	ESP,ExAC,TOPMed,gnomAD
rs1271315936	p.Gln1800His	missense variant	-	NC_000010.11:g.89773985G>C	TOPMed
rs758082529	p.Lys1801Glu	missense variant	-	NC_000010.11:g.89773986A>G	ExAC,gnomAD
rs753144923	p.His1807Gln	missense variant	-	NC_000010.11:g.89774006C>A	ExAC,TOPMed,gnomAD
rs1286112721	p.Ile1809Leu	missense variant	-	NC_000010.11:g.89774010A>C	TOPMed
rs756642620	p.Lys1811Arg	missense variant	-	NC_000010.11:g.89774017A>G	ExAC,gnomAD
rs778476119	p.Arg1812Ter	stop gained	-	NC_000010.11:g.89774019C>T	ExAC,gnomAD
rs1325967536	p.Arg1812Gln	missense variant	-	NC_000010.11:g.89774020G>A	TOPMed,gnomAD
rs757350037	p.Arg1813Gln	missense variant	-	NC_000010.11:g.89774023G>A	ExAC,TOPMed,gnomAD
rs372021958	p.Arg1813Ter	stop gained	-	NC_000010.11:g.89774022C>T	ESP,ExAC,TOPMed,gnomAD
rs779186213	p.Leu1814Phe	missense variant	-	NC_000010.11:g.89774025C>T	ExAC,gnomAD
rs202099671	p.Arg1815Ter	stop gained	-	NC_000010.11:g.89774028C>T	ExAC,TOPMed,gnomAD
COSM198308	p.Arg1815Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000010.11:g.89774029G>A	NCI-TCGA Cosmic
rs772307724	p.Thr1818Lys	missense variant	-	NC_000010.11:g.89774038C>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Thr1818GlnPheSerTerUnkUnk	frameshift	-	NC_000010.11:g.89774033A>-	NCI-TCGA
NCI-TCGA novel	p.Thr1818AsnPheSerTerUnkUnk	frameshift	-	NC_000010.11:g.89774032_89774033insA	NCI-TCGA
rs775213487	p.Ala1819Thr	missense variant	-	NC_000010.11:g.89774040G>A	ExAC,gnomAD
rs962046645	p.Ala1819Val	missense variant	-	NC_000010.11:g.89774041C>T	TOPMed
rs375603161	p.Lys1820Glu	missense variant	-	NC_000010.11:g.89774043A>G	ESP,ExAC,TOPMed,gnomAD
rs1245786437	p.Ter1821Unk	stop lost	-	NC_000010.11:g.89774046del	gnomAD
rs1446026362	p.Ter1821Tyr	stop lost	-	NC_000010.11:g.89774048A>T	TOPMed,gnomAD

Disease or phenotype associated information

Disease ID	Disease Name	Disease Type	Source
C0005684	Malignant neoplasm of urinary bladder	disease	BEFREE
C0005695	Bladder Neoplasm	group	BEFREE
C0006142	Malignant neoplasm of breast	disease	BEFREE
C0017636	Glioblastoma	disease	BEFREE
C0025958	Microcephaly	disease	MGD
C0524851	Neurodegenerative Disorders	group	BEFREE
C0596263	Carcinogenesis	phenotype	BEFREE
C0678222	Breast Carcinoma	disease	BEFREE
C0699885	Carcinoma of bladder	disease	BEFREE
C1458155	Mammary Neoplasms	group	BEFREE
C2239176	Liver carcinoma	disease	BEFREE

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO ID	GO Term	Evidence
GO:0003777	microtubule motor activity	IBA
GO:0005515	protein binding	IPI
GO:0005524	ATP binding	IEA
GO:0008017	microtubule binding	IDA
GO:0008017	microtubule binding	IBA
GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed	IDA
GO:0016887	ATPase activity	IDA
GO:0016887	ATPase activity	IBA
GO:0042803	protein homodimerization activity	IDA
GO:0050699	WW domain binding	IPI

GO:Biological Process

GO ID	GO Term	Evidence
GO:0001843	neural tube closure	IEA
GO:0007018	microtubule-based movement	IBA
GO:0007050	cell cycle arrest	NAS
GO:0007088	regulation of mitotic nuclear division	NAS
GO:0008284	positive regulation of cell population proliferation	ISS
GO:0008284	positive regulation of cell population proliferation	IMP
GO:0032467	positive regulation of cytokinesis	IMP
GO:0035372	protein localization to microtubule	ISS
GO:0048812	neuron projection morphogenesis	ISS
GO:0051301	cell division	IEA
GO:0090316	positive regulation of intracellular protein transport	ISS
GO:1903438	positive regulation of mitotic cytokinetic process	ISS
GO:2000114	regulation of establishment of cell polarity	ISS
GO:2001224	positive regulation of neuron migration	ISS

GO:Cellular Component

GO ID	GO Term	Evidence
GO:0005634	nucleus	IDA
GO:0005634	nucleus	IBA
GO:0005654	nucleoplasm	IDA
GO:0005730	nucleolus	IDA
GO:0005737	cytoplasm	IDA
GO:0005813	centrosome	IDA
GO:0005829	cytosol	IDA
GO:0005871	kinesin complex	IBA
GO:0005874	microtubule	IBA
GO:0030426	growth cone	IEA
GO:0030496	midbody	ISS
GO:0030496	midbody	IDA
GO:0045171	intercellular bridge	IDA
GO:0048471	perinuclear region of cytoplasm	ISS
GO:0051233	spindle midzone	ISS
GO:0070938	contractile ring	IDA
GO:0097431	mitotic spindle pole	IDA
GO:1990023	mitotic spindle midzone	IDA

Reactome Pathway

Reactome ID	Reactome Term	Evidence
R-HSA-109582	Hemostasis	TAS
R-HSA-199991	Membrane Trafficking	TAS
R-HSA-5653656	Vesicle-mediated transport	TAS
R-HSA-6811434	COPI-dependent Golgi-to-ER retrograde traffic	TAS
R-HSA-6811442	Intra-Golgi and retrograde Golgi-to-ER traffic	TAS
R-HSA-8856688	Golgi-to-ER retrograde transport	TAS
R-HSA-983189	Kinesins	TAS
R-HSA-983231	Factors involved in megakaryocyte development and platelet production	TAS

Drugs and compounds information

ID	Drug Name	Action	PubMed
C026486	1,2,5,6-dibenzanthracene	1,2,5,6-dibenzanthracene results in increased expression of KIF20B mRNA	26377693
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of KIF20B mRNA	22698814; 28903501;
D015655	1-Methyl-4-phenylpyridinium	1-Methyl-4-phenylpyridinium results in decreased expression of KIF20B mRNA	24810058
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of KIF20B mRNA	30723492
C029790	2,2',3',4,4',5-hexachlorobiphenyl	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KIF20B mRNA	25510870
C063002	2,3-dimethoxy-1,4-naphthoquinone	2,3-dimethoxy-1,4-naphthoquinone results in increased expression of KIF20B mRNA	19031421
C081766	2,4,4'-trichlorobiphenyl	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KIF20B mRNA	25510870
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KIF20B mRNA	25510870
C009828	2,4,5,2',5'-pentachlorobiphenyl	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KIF20B mRNA	25510870
C009407	2,5,2',5'-tetrachlorobiphenyl	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KIF20B mRNA	25510870
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in decreased expression of KIF20B mRNA	19191707
C082164	4-methoxycinnamate methyl ester	4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA]	19442820
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of KIF20B mRNA	20382639
D000082	Acetaminophen	Acetaminophen results in increased expression of KIF20B mRNA	22230336
D020106	Acrylamide	Acrylamide results in increased expression of KIF20B mRNA	28959563
C006418	adrenocorticotropin zinc	adrenocorticotropin zinc results in decreased expression of KIF20B mRNA	19920212
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of KIF20B protein	20106945
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased methylation of KIF20B gene	27153756
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of KIF20B mRNA	23630614; 25378103;
C000593263	afuresertib	afuresertib results in decreased expression of KIF20B mRNA	28960945
D000393	Air Pollutants	Air Pollutants analog results in decreased expression of KIF20B mRNA	21757418
D001241	Aspirin	Aspirin results in decreased expression of KIF20B mRNA	11906190
D001280	Atrazine	Atrazine results in increased expression of KIF20B mRNA	22982499
C105832	aurapten	aurapten affects the expression of KIF20B mRNA	23320178
D001379	Azathioprine	Azathioprine results in decreased expression of KIF20B mRNA	22623647
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in increased expression of KIF20B mRNA	26377693
C006780	bisphenol A	bisphenol A results in decreased expression of KIF20B mRNA	29275510
C006780	bisphenol A	bisphenol A results in decreased expression of KIF20B mRNA	25181051
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide results in increased phosphorylation of KIF20B protein	22174045
C018475	butyraldehyde	butyraldehyde results in decreased expression of KIF20B mRNA	26079696
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of KIF20B mRNA	24982889
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of KIF20B mRNA	25993096
C040048	caffeic acid	caffeic acid promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA]	19442820
D002117	Calcitriol	Calcitriol results in decreased expression of KIF20B mRNA	21592394
D002117	Calcitriol	[Testosterone co-treated with Calcitriol] results in decreased expression of KIF20B mRNA	21592394
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of KIF20B mRNA	17484886
D002945	Cisplatin	Cisplatin results in increased phosphorylation of KIF20B protein	22006019
D019327	Copper Sulfate	Copper Sulfate results in decreased expression of KIF20B mRNA	19549813
C030973	cupric oxide	cupric oxide results in decreased expression of KIF20B mRNA	22077320
D016572	Cyclosporine	Cyclosporine results in decreased expression of KIF20B mRNA	20106945; 25562108;
D000069439	Dasatinib	Dasatinib results in decreased expression of KIF20B mRNA	20579391
D003976	Diazinon	Diazinon affects the expression of KIF20B mRNA	22546817
D003999	Dichloroacetic Acid	Dichloroacetic Acid results in increased expression of KIF20B mRNA	28962523
C000944	dicrotophos	dicrotophos results in decreased expression of KIF20B mRNA	28302478
D004026	Dieldrin	Dieldrin affects the expression of KIF20B mRNA	22546817
D004365	Drugs, Chinese Herbal	Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA]	19442820
C045651	epigallocatechin gallate	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF20B mRNA	22079256
C472787	erucylphospho-N,N,N-trimethylpropylammonium	erucylphospho-N,N,N-trimethylpropylammonium results in decreased expression of KIF20B mRNA	29464035
D004918	Erythromycin Estolate	Erythromycin Estolate results in decreased expression of KIF20B mRNA	24412560
D004918	Erythromycin Estolate	Erythromycin Estolate results in increased expression of KIF20B mRNA	24412560
C069837	fullerene C60	fullerene C60 results in increased expression of KIF20B mRNA	19167457
C039281	furan	furan results in increased expression of KIF20B mRNA	25539665
C004312	glycidol	glycidol results in increased expression of KIF20B mRNA	24915197
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of KIF20B mRNA	20044591
C492448	ICG 001	ICG 001 results in decreased expression of KIF20B mRNA	26191083
C545476	incobotulinumtoxinA	incobotulinumtoxinA results in decreased expression of KIF20B mRNA	29522793
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KIF20B mRNA	25613284
D007854	Lead	Lead affects the expression of KIF20B mRNA	28903495
D000077339	Leflunomide	Leflunomide results in decreased expression of KIF20B mRNA	28988120
D008154	Lucanthone	Lucanthone results in decreased expression of KIF20B mRNA	21148553
D058185	Magnetite Nanoparticles	[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of KIF20B mRNA	21641980
C008493	methylselenic acid	methylselenic acid results in decreased expression of KIF20B mRNA	12517777
C406082	monomethylarsonous acid	monomethylarsonous acid results in decreased expression of KIF20B protein	24625837
D009151	Mustard Gas	Mustard Gas results in decreased expression of KIF20B mRNA	25102026
D037742	Nanotubes, Carbon	Nanotubes, Carbon analog results in increased expression of KIF20B mRNA	25554681
D037742	Nanotubes, Carbon	Nanotubes, Carbon results in increased expression of KIF20B mRNA	25554681
C029938	nickel sulfate	nickel sulfate results in decreased expression of KIF20B mRNA	22714537
C570897	NSC668394	NSC668394 results in decreased expression of KIF20B mRNA	27137931
D000077150	Oxaliplatin	[Oxaliplatin co-treated with Topotecan] results in decreased expression of KIF20B mRNA	25729387
D000077150	Oxaliplatin	Oxaliplatin results in decreased expression of KIF20B mRNA	25729387
D010100	Oxygen	Oxygen deficiency results in decreased expression of KIF20B mRNA	26516004
D010126	Ozone	[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of KIF20B mRNA	25658374
D052638	Particulate Matter	Particulate Matter results in decreased expression of KIF20B mRNA	15046786
C410127	PCB 180	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KIF20B mRNA	25510870
D010629	Phenformin	Phenformin results in decreased expression of KIF20B mRNA	31324951
D010634	Phenobarbital	Phenobarbital affects the expression of KIF20B mRNA	23091169
C006253	pirinixic acid	[pirinixic acid co-treated with PPARA] results in increased expression of KIF20B mRNA	20813756
C006253	pirinixic acid	pirinixic acid results in increased expression of KIF20B mRNA	20813756; 23811191;
D010936	Plant Extracts	Plant Extracts results in increased expression of KIF20B mRNA	23557933
C027373	potassium chromate(VI)	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF20B mRNA	22079256
C027373	potassium chromate(VI)	potassium chromate(VI) results in decreased expression of KIF20B mRNA	22079256
D017035	Pravastatin	Pravastatin affects the expression of KIF20B mRNA	27225895
D017035	Pravastatin	Pravastatin results in decreased expression of KIF20B mRNA	27225895
C005556	propionaldehyde	propionaldehyde results in decreased expression of KIF20B mRNA	26079696
D011691	Puromycin	[Tretinoin co-treated with Puromycin] results in increased expression of KIF20B mRNA	15977162
D011794	Quercetin	Quercetin results in decreased expression of KIF20B mRNA	15309432
D012402	Rotenone	Rotenone results in decreased expression of KIF20B mRNA	28374803
C017947	sodium arsenite	sodium arsenite results in decreased expression of KIF20B mRNA	22714537
D053260	Soot	Soot results in increased expression of KIF20B mRNA	26551751
C075117	squalestatin 1	squalestatin 1 results in decreased expression of KIF20B mRNA	27225895
D004113	Succimer	[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of KIF20B mRNA	21641980
D000077210	Sunitinib	Sunitinib results in decreased expression of KIF20B mRNA	31533062
D013739	Testosterone	[Testosterone co-treated with Calcitriol] results in decreased expression of KIF20B mRNA	21592394
D013739	Testosterone	Testosterone results in decreased expression of KIF20B mRNA	21592394
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of KIF20B mRNA	21802500
D013750	Tetrachloroethylene	Tetrachloroethylene results in decreased expression of KIF20B mRNA	28973375
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in increased expression of KIF20B mRNA	19031421
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KIF20B mRNA	25613284
D019284	Thapsigargin	4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA]	19442820
D019284	Thapsigargin	caffeic acid promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA]	19442820
D019284	Thapsigargin	Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA]	19442820
D019284	Thapsigargin	Thapsigargin results in increased expression of KIF20B mRNA	19442820
D013853	Thioacetamide	Thioacetamide results in increased expression of KIF20B mRNA	23411599
C009495	titanium dioxide	titanium dioxide results in increased expression of KIF20B mRNA	30012374
D019772	Topotecan	[Oxaliplatin co-treated with Topotecan] results in decreased expression of KIF20B mRNA	25729387
D019772	Topotecan	Topotecan results in decreased expression of KIF20B mRNA	25729387
D014212	Tretinoin	[Tretinoin co-treated with Puromycin] results in increased expression of KIF20B mRNA	15977162
D014241	Trichloroethylene	Trichloroethylene results in increased expression of KIF20B mRNA	25549359
C015559	trimellitic anhydride	trimellitic anhydride results in increased expression of KIF20B mRNA	19042947
C016805	tris(1,3-dichloro-2-propyl)phosphate	tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of KIF20B mRNA	26179874
D000077288	Troglitazone	Troglitazone results in decreased expression of KIF20B mRNA	19140230
D014635	Valproic Acid	Valproic Acid results in decreased expression of KIF20B mRNA	19949822; 23179753; 27188386;
D014638	Vanadates	Vanadates results in decreased expression of KIF20B mRNA	22714537
D001335	Vehicle Emissions	Vehicle Emissions results in decreased expression of KIF20B mRNA	15046786
D001335	Vehicle Emissions	Vehicle Emissions results in increased methylation of KIF20B gene	25560391

Functional annotations

Keywords

Keyword ID	Keyword Term
KW-0025	Alternative splicing
KW-0067	ATP-binding
KW-0131	Cell cycle
KW-0132	Cell division
KW-0966	Cell projection
KW-0175	Coiled coil
KW-0963	Cytoplasm
KW-0206	Cytoskeleton
KW-0493	Microtubule
KW-0498	Mitosis
KW-0505	Motor protein
KW-0547	Nucleotide-binding
KW-0539	Nucleus
KW-0553	Oncogene
KW-0597	Phosphoprotein
KW-0621	Polymorphism
KW-1185	Reference proteome

Interpro

InterPro ID	InterPro Term
IPR028828	KIF20B
IPR027640	Kinesin-like_fam
IPR019821	Kinesin_motor_CS
IPR001752	Kinesin_motor_dom
IPR036961	Kinesin_motor_dom_sf
IPR027417	P-loop_NTPase

PROSITE

PROSITE ID	PROSITE Term
PS00411	KINESIN_MOTOR_1
PS50067	KINESIN_MOTOR_2

Pfam

Pfam ID	Pfam Term
PF00225	Kinesin

Gene: KIF20B

Basic information

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Other genetic variants/mutations

Disease or phenotype associated information

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO:Biological Process

GO:Cellular Component

Reactome Pathway

Drugs and compounds information

Functional annotations

Keywords

Interpro

PROSITE

Pfam

Protein-protein interaction

Protein-miRNA interaction