| Tag |
Content |
| Uniprot ID |
Q9GL23
|
| Entrez ID |
|
| Genbank protein ID |
CAC17122.1 |
| Genbank nucleotide ID |
|
| Ensembl protein ID |
|
| Ensembl nucleotide ID |
|
|
Gene name
|
Apoptotic protease-activating factor 1 |
|
Gene symbol
|
APAF1 |
|
Organism
|
Canis lupus familiaris |
|
NCBI taxa ID
|
9615 |
|
Cleft type
|
|
|
Developmental stage
|
|
|
Data sources
|
Homology search |
| Reference |
|
|
Functional description
|
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase 9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). |
Sequence
| ILKKDNYSYI SFYNALIHEG YKDLAALLHS GIPVISSSNG GKDSVGGITS |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
