| Tag | Content |
|---|---|
| Uniprot ID | Q9GL23 |
| Entrez ID | |
| Genbank protein ID | CAC17122.1 |
| Genbank nucleotide ID | |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Apoptotic protease-activating factor 1 |
| Gene symbol | APAF1 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase 9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). |
| Sequence | ILKKDNYSYI SFYNALIHEG YKDLAALLHS GIPVISSSNG GKDSVGGITS |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
Protein disorder visualization from D2P2 is currently unavailable.
| GO ID | GO Term |
|---|---|
| GO:0005524 | ATP binding |
| GO:0006915 | apoptotic process |