| Tag | Content |
|---|---|
| Uniprot ID | Q9H0Q0; B3KNZ1; Q53QW2; |
| Entrez ID | 81553 |
| Genbank protein ID | CAG38535.1; CAB66639.1; AAH38971.1; EAX00879.1; AAY24282.1; BAG37539.1; BAG51503.1; |
| Genbank nucleotide ID | XM_006712108.3; NM_030797.3; XM_005262630.3; |
| Ensembl protein ID | ENSP00000384771; ENSP00000370724; |
| Ensembl nucleotide ID | ENSG00000197872 |
| Gene name | CYFIP-related Rac1 interactor A |
| Gene symbol | CYRIA |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 27033726 |
| Functional description | May negatively regulate RAC1 signaling and RAC1-driven cytoskeletal remodeling (Probable). May regulate chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions (Probable). |
| Sequence | MGNLLKVLTR EIENYPHFFL DFENAQPTEG EREIWNQISA VLQDSESILA DLQAYKGAGP 60 EIRDAIQNPN DIQLQEKAWN AVCPLVVRLK RFYEFSIRLE KALQSLLESL TCPPYTPTQH 120 LEREQALAKE FAEILHFTLR FDELKMRNPA IQNDFSYYRR TISRNRINNM HLDIENEVNN 180 EMANRMSLFY AEATPMLKTL SNATMHFVSE NKTLPIENTT DCLSTMTSVC KVMLETPEYR 240 SRFTSEETLM FCMRVMVGVI ILYDHVHPVG AFCKTSKIDM KGCIKVLKEQ APDSVEGLLN 300 ALRFTTKHLN DESTSKQIRA MLQ 323 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.