| Tag | Content |
|---|---|
| Uniprot ID | Q9H161; Q96JN7; Q9H198; Q9HAY9; |
| Entrez ID | 60529 |
| Genbank protein ID | AAK38835.1; BAB47417.1; AAG23961.1; CAC15120.1; CAC15060.1; |
| Genbank nucleotide ID | NM_021926.3 |
| Ensembl protein ID | ENSP00000498217 |
| Ensembl nucleotide ID | ENSG00000052850 |
| Gene name | Homeobox protein aristaless-like 4 |
| Gene symbol | ALX4 |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development. |
| Sequence | MNAETCVSYC ESPAAAMDAY YSPVSQSREG SSPFRAFPGG DKFGTTFLSA AAKAQGFGDA 60 KSRARYGAGQ QDLATPLESG AGARGSFNKF QPQPSTPQPQ PPPQPQPQQQ QPQPQPPAQP 120 HLYLQRGACK TPPDGSLKLQ EGSSGHSAAL QVPCYAKESS LGEPELPPDS DTVGMDSSYL 180 SVKEAGVKGP QDRASSDLPS PLEKADSESN KGKKRRNRTT FTSYQLEELE KVFQKTHYPD 240 VYAREQLAMR TDLTEARVQV WFQNRRAKWR KRERFGQMQQ VRTHFSTAYE LPLLTRAENY 300 AQIQNPSWLG NNGAASPVPA CVVPCDPVPA CMSPHAHPPG SGASSVTDFL SVSGAGSHVG 360 QTHMGSLFGA ASLSPGLNGY ELNGEPDRKT SSIAALRMKA KEHSAAISWA T 411 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.