CleftGeneDB-Search

Gene: TANC2

Basic information

Tag	Content
Uniprot ID	Q9HCD6; Q9HAC3; Q9NW88; Q9NXY9; Q9ULS2;
Entrez ID	26115
Genbank protein ID	CAB92314.1; BAB13462.2; BAA86462.2;
Genbank nucleotide ID	NM_025185.3; XM_005257203.4;
Ensembl protein ID	ENSP00000387593; ENSP00000374171;
Ensembl nucleotide ID	ENSG00000170921
Gene name	Protein TANC2
Gene symbol	TANC2
Organism	Homo sapiens
NCBI taxa ID	9606
Cleft type
Developmental stage
Data sources	Manually collected
Reference	27033726
Functional description	Scaffolding protein in the dendritic spines which acts as immobile postsynaptic posts able to recruit KIF1A-driven dense core vesicles to dendritic spines.
Sequence	MFRNSLKMLL TGGKSSRKNR SSDGGSEEPP DRRQSSVDSR QSRSGQGGIS TESDCAFEPD 60 YAVPPLPVSE GDAEQELGPP PSVDEAANTL MTRLGFLLGE KVTEVQPGDQ YSMEVQDENQ 120 TSAITQRISP CSTLTSSTAS PPASSPCSTL PPISTNATAK DCSYGAVTSP TSTLESRDSG 180 IIATLTSYSE NVERTKYAGE SSKELGSGGN IKPWQSQKSS MDSCLYRVDE NMTASTYSLN 240 KIPERNLETV LSQSVQSIPL YLMPRPNSVA ATSSAHLEDL AYLDEQRHTP LRTSLRMPRQ 300 SMGGARTQQD LRVRFAPYRP PDISLKPLLF EVPSITTESV FVGRDWVFHE IDAQLQSSNA 360 SVNQGVVIVG NIGFGKTAII SRLVALSCHG TRMRQIASDS PHASPKHVDA NRELPLTQPP 420 SAHSSITSGS CPGTPEMRRR QEEAMRRLAS QVVAYHYCQA DNAYTCLVPE FVHNVAALLC 480 RSPQLTAYRE QLLREPHLQS MLSLRSCVQD PMASFRRGVL EPLENLHKER KIPDEDFIIL 540 IDGLNEAEFH KPDYGDTIVS FLSKMIGKFP SWLKLIVTVR TSLQEITKLL PFHRIFLDRL 600 EENEAIDQDL QAYILHRIHS SSEIQNNISL NGKMDNTTFG KLSSHLKTLS QGSYLYLKLT 660 FDLIEKGYLV LKSSSYKVVP VSLSEVYLLQ CNMKFPTQSS FDRVMPLLNV AVASLHPLTD 720 EHIFQAINAG SIEGTLEWED FQQRMENLSM FLIKRRDMTR MFVHPSFREW LIWREEGEKT 780 KFLCDPRSGH TLLAFWFSRQ EGKLNRQQTI ELGHHILKAH IFKGLSKKVG VSSSILQGLW 840 ISYSTEGLSM ALASLRNLYT PNIKVSRLLI LGGANINYRT EVLNNAPILC VQSHLGYTEM 900 VALLLEFGAN VDASSESGLT PLGYAAAAGY LSIVVLLCKK RAKVDHLDKN GQCALVHAAL 960 RGHLEVVKFL IQCDWTMAGQ QQGVFKKSHA IQQALIAAAS MGYTEIVSYL LDLPEKDEEE 1020 VERAQINSFD SLWGETALTA AAGRGKLEVC RLLLEQGAAV AQPNRRGAVP LFSTVRQGHW 1080 QIVDLLLTHG ADVNMADKQG RTPLMMAASE GHLGTVDFLL AQGASIALMD KEGLTALSWA 1140 CLKGHLSVVR SLVDNGAATD HADKNGRTPL DLAAFYGDAE VVQFLVDHGA MIEHVDYSGM 1200 RPLDRAVGCR NTSVVVTLLK KGAKIGPATW AMATSKPDIM IILLSKLMEE GDMFYKKGKV 1260 KEAAQRYQYA LKKFPREGFG EDLKTFRELK VSLLLNLSRC RRKMNDFGMA EEFATKALEL 1320 KPKSYEAYYA RARAKRSSRQ FAAALEDLNE AIKLCPNNRE IQRLLLRVEE ECRQMQQPQQ 1380 PPPPPQPQQQ LPEEAEPEPQ HEDIYSVQDI FEEEYLEQDV ENVSIGLQTE ARPSQGLPVI 1440 QSPPSSPPHR DSAYISSSPL GSHQVFDFRS SSSVGSPTRQ TYQSTSPALS PTHQNSHYRP 1500 SPPHTSPAHQ GGSYRFSPPP VGGQGKEYPS PPPSPLRRGP QYRASPPAES MSVYRSQSGS 1560 PVRYQQETSV SQLPGRPKSP LSKMAQRPYQ MPQLPVAVPQ QGLRLQPAKA QIVRSNQPSP 1620 AVHSSTVIPT GAYGQVAHSM ASKYQSSQGD IGVSQSRLVY QGSIGGIVGD GRPVQHVQAS 1680 LSAGAICQHG GLTKEDLPQR PSSAYRGGVR YSQTPQIGRS QSASYYPVCH SKLDLERSSS 1740 QLGSPDVSHL IRRPISVNPN EIKPHPPTPR PLLHSQSVGL RFSPSSNSIS STSNLTPTFR 1800 PSSSIQQMEI PLKPAYERSC DELSPVSPTQ GGYPSEPTRS RTTPFMGIID KTARTQQYPH 1860 LHQQNRTWAV SSVDTVLSPT SPGNLPQPES FSPPSSISNI AFYNKTNNAQ NGHLLEDDYY 1920 SPHGMLANGS RGDLLERVSQ ASSYPDVKVA RTLPVAQAYQ DNLYRQLSRD SRQGQTSPIK 1980 PKRPFVESNV

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Relation	Gene symbol	Entrez ID	UniProt ID	Species	Evidence	Details
1:1 ortholog	TANC2		F1PAF9	Canis lupus familiaris	Prediction	More>>
1:1 ortholog	TANC2		A0A452DN91	Capra hircus	Prediction	More>>
1:1 ortholog	TANC2	26115	Q9HCD6	Homo sapiens	Publication	More>>
1:1 ortholog	Tanc2	77097	A2A690	Mus musculus	Prediction	More>>
1:1 ortholog	TANC2	454784	H2QDM5	Pan troglodytes	Prediction	More>>
1:1 ortholog	TANC2		F1RRV1	Sus scrofa	Prediction	More>>
1:1 ortholog	Tanc2	303599	A0A0G2K9J0	Rattus norvegicus	Prediction	More>>

Identified variants/mutations related to cleft phenotype

Gene symbol	Significant Variants/SNPS	Methods	PubMed ID
TANC2	rs1588366	Genotyping and GWAS	27033726

Other genetic variants/mutations

ID	Variant	Type	Disease	Chromosome\Coordinate	Evidence
rs1293013054	p.Phe2Ile	missense variant	-	NC_000017.11:g.63009563T>A	gnomAD
rs762051832	p.Arg3Gln	missense variant	-	NC_000017.11:g.63009567G>A	ExAC,TOPMed
rs199889425	p.Ser5Gly	missense variant	-	NC_000017.11:g.63009572A>G	1000Genomes,ExAC,gnomAD
COSM5429187	p.Ser5Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63009573G>A	NCI-TCGA Cosmic
NCI-TCGA novel	p.Leu6Phe	missense variant	-	NC_000017.11:g.63009575C>T	NCI-TCGA
rs376072973	p.Thr11Ala	missense variant	-	NC_000017.11:g.63009590A>G	ESP,TOPMed
rs751404068	p.Gly12Ala	missense variant	-	NC_000017.11:g.63009594G>C	ExAC,gnomAD
rs751404068	p.Gly12Asp	missense variant	-	NC_000017.11:g.63009594G>A	ExAC,gnomAD
rs1221837434	p.Ser16Gly	missense variant	-	NC_000017.11:g.63009605A>G	TOPMed,gnomAD
rs1271573443	p.Ser16Asn	missense variant	-	NC_000017.11:g.63009606G>A	gnomAD
rs759452024	p.Arg17Cys	missense variant	-	NC_000017.11:g.63009608C>T	ExAC,TOPMed,gnomAD
rs767416460	p.Arg17His	missense variant	-	NC_000017.11:g.63009609G>A	ExAC,gnomAD
rs201847314	p.Lys18Arg	missense variant	-	NC_000017.11:g.63009612A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs755518950	p.Asn19Ser	missense variant	-	NC_000017.11:g.63009615A>G	ExAC,gnomAD
NCI-TCGA novel	p.Arg20LysPheSerTerUnk	stop gained	-	NC_000017.11:g.63009616_63009617insAAATAAAAATTTAAAA	NCI-TCGA
rs777377517	p.Arg20Lys	missense variant	-	NC_000017.11:g.63009618G>A	ExAC,gnomAD
NCI-TCGA novel	p.Ser21LysPheSerTerUnkUnk	frameshift	-	NC_000017.11:g.63009618_63009619insAAAAAAGAAAACTT	NCI-TCGA
rs1452667303	p.Ser22Asn	missense variant	-	NC_000017.11:g.63009624G>A	TOPMed
rs753461149	p.Asp23Glu	missense variant	-	NC_000017.11:g.63073944T>A	ExAC,gnomAD
rs368947999	p.Ser26Arg	missense variant	-	NC_000017.11:g.63073953C>G	ESP,ExAC,TOPMed,gnomAD
rs764916506	p.Glu27Lys	missense variant	-	NC_000017.11:g.63073954G>A	ExAC,gnomAD
rs1279640435	p.Glu28Lys	missense variant	-	NC_000017.11:g.63073957G>A	gnomAD
rs1407515069	p.Pro29Leu	missense variant	-	NC_000017.11:g.63073961C>T	TOPMed,gnomAD
rs750115471	p.Pro29Ala	missense variant	-	NC_000017.11:g.63073960C>G	ExAC,TOPMed,gnomAD
rs1437062053	p.Pro30Leu	missense variant	-	NC_000017.11:g.63073964C>T	TOPMed
rs747441098	p.Asp31Asn	missense variant	-	NC_000017.11:g.63073966G>A	ExAC,gnomAD
rs1215467764	p.Arg32Gln	missense variant	-	NC_000017.11:g.63073970G>A	TOPMed,gnomAD
rs1468782400	p.Arg32Gly	missense variant	-	NC_000017.11:g.63073969C>G	gnomAD
rs1467980101	p.Ser35Leu	missense variant	-	NC_000017.11:g.63073979C>T	gnomAD
rs1198178736	p.Ser36Asn	missense variant	-	NC_000017.11:g.63073982G>A	TOPMed,gnomAD
rs755557492	p.Ser36Arg	missense variant	-	NC_000017.11:g.63073983T>A	ExAC,TOPMed,gnomAD
rs1198178736	p.Ser36Thr	missense variant	-	NC_000017.11:g.63073982G>C	TOPMed,gnomAD
rs781235539	p.Asp38Glu	missense variant	-	NC_000017.11:g.63073989C>A	ExAC,gnomAD
rs749544865	p.Arg40Leu	missense variant	-	NC_000017.11:g.63073994G>T	ExAC,TOPMed,gnomAD
rs183360210	p.Arg40Cys	missense variant	-	NC_000017.11:g.63073993C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs183360210	p.Arg40Ser	missense variant	-	NC_000017.11:g.63073993C>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Arg40ProPheSerTerUnkUnk	frameshift	-	NC_000017.11:g.63073989_63073990CT>-	NCI-TCGA
rs749544865	p.Arg40His	missense variant	-	NC_000017.11:g.63073994G>A	ExAC,TOPMed,gnomAD
rs183360210	p.Arg40Gly	missense variant	-	NC_000017.11:g.63073993C>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs760520399	p.Arg43His	missense variant	-	NC_000017.11:g.63074003G>A	ExAC,TOPMed,gnomAD
rs200043598	p.Arg43Cys	missense variant	-	NC_000017.11:g.63074002C>T	ESP,ExAC,TOPMed,gnomAD
rs1337050229	p.Ser44Pro	missense variant	-	NC_000017.11:g.63074005T>C	gnomAD
rs868711987	p.Gly47Cys	missense variant	-	NC_000017.11:g.63074014G>T	gnomAD
rs868711987	p.Gly47Ser	missense variant	-	NC_000017.11:g.63074014G>A	gnomAD
rs1194084981	p.Gly48Asp	missense variant	-	NC_000017.11:g.63099178G>A	TOPMed,gnomAD
rs1194084981	p.Gly48Asp	missense variant	-	NC_000017.11:g.63099178G>A	NCI-TCGA
rs1194084981	p.Gly48Val	missense variant	-	NC_000017.11:g.63099178G>T	TOPMed,gnomAD
rs777873115	p.Ile49Asn	missense variant	-	NC_000017.11:g.63099181T>A	ExAC,TOPMed,gnomAD
rs777873115	p.Ile49Thr	missense variant	-	NC_000017.11:g.63099181T>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ser50Cys	missense variant	-	NC_000017.11:g.63099184C>G	NCI-TCGA
rs1315894538	p.Thr51Ala	missense variant	-	NC_000017.11:g.63099186A>G	TOPMed
rs1255812940	p.Glu52Lys	missense variant	-	NC_000017.11:g.63099189G>A	gnomAD
rs373822154	p.Asp54Asn	missense variant	-	NC_000017.11:g.63099195G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1375215908	p.Asp54Gly	missense variant	-	NC_000017.11:g.63099196A>G	gnomAD
rs746751671	p.Cys55Ser	missense variant	-	NC_000017.11:g.63099199G>C	ExAC,TOPMed,gnomAD
rs957239518	p.Cys55Trp	missense variant	-	NC_000017.11:g.63099200T>G	TOPMed,gnomAD
rs775147144	p.Cys55Arg	missense variant	-	NC_000017.11:g.63099198T>C	ExAC,gnomAD
rs746751671	p.Cys55Tyr	missense variant	-	NC_000017.11:g.63099199G>A	ExAC,TOPMed,gnomAD
rs1375554395	p.Glu58Lys	missense variant	-	NC_000017.11:g.63099207G>A	gnomAD
rs1436156823	p.Asp60Gly	missense variant	-	NC_000017.11:g.63099214A>G	gnomAD
rs768584624	p.Tyr61Cys	missense variant	-	NC_000017.11:g.63099217A>G	ExAC,gnomAD
rs377328939	p.Ala62Thr	missense variant	-	NC_000017.11:g.63099219G>A	ESP,ExAC,TOPMed,gnomAD
rs754479608	p.Pro64Leu	missense variant	-	NC_000017.11:g.63099226C>T	ExAC,gnomAD
rs751172282	p.Pro65Ser	missense variant	-	NC_000017.11:g.63099228C>T	ExAC,gnomAD
rs376757064	p.Leu66Pro	missense variant	-	NC_000017.11:g.63099232T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs767889295	p.Leu66Val	missense variant	-	NC_000017.11:g.63099231C>G	ExAC,gnomAD
rs756666637	p.Pro67Ser	missense variant	-	NC_000017.11:g.63099234C>T	NCI-TCGA
rs756666637	p.Pro67Ser	missense variant	-	NC_000017.11:g.63099234C>T	ExAC,TOPMed,gnomAD
rs756666637	p.Pro67Ala	missense variant	-	NC_000017.11:g.63099234C>G	ExAC,TOPMed,gnomAD
rs754020906	p.Val68Leu	missense variant	-	NC_000017.11:g.63099237G>T	ExAC,TOPMed,gnomAD
rs1445736600	p.Ser69Arg	missense variant	-	NC_000017.11:g.63099240A>C	gnomAD
rs552420639	p.Ser69Asn	missense variant	-	NC_000017.11:g.63099241G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs552420639	p.Ser69Asn	missense variant	-	NC_000017.11:g.63099241G>A	NCI-TCGA,NCI-TCGA Cosmic
rs1292553380	p.Ser69Arg	missense variant	-	NC_000017.11:g.63099242T>G	TOPMed
rs552420639	p.Ser69Thr	missense variant	-	NC_000017.11:g.63099241G>C	1000Genomes,ExAC,TOPMed,gnomAD
rs1395135042	p.Glu70Gln	missense variant	-	NC_000017.11:g.63099243G>C	gnomAD
rs779139258	p.Glu70Ala	missense variant	-	NC_000017.11:g.63099244A>C	ExAC,gnomAD
rs1205926778	p.Gly71Asp	missense variant	-	NC_000017.11:g.63193991G>A	gnomAD
rs769716095	p.Asp72Glu	missense variant	-	NC_000017.11:g.63193995T>A	ExAC,TOPMed,gnomAD
rs1482500371	p.Leu77Phe	missense variant	-	NC_000017.11:g.63194008C>T	gnomAD
rs749201325	p.Pro79Ser	missense variant	-	NC_000017.11:g.63194014C>T	ExAC,gnomAD
rs1420055688	p.Pro80His	missense variant	-	NC_000017.11:g.63194018C>A	gnomAD
rs770432077	p.Pro80Ala	missense variant	-	NC_000017.11:g.63194017C>G	ExAC,gnomAD
rs1420055688	p.Pro80Arg	missense variant	-	NC_000017.11:g.63194018C>G	gnomAD
rs1420055688	p.Pro80Leu	missense variant	-	NC_000017.11:g.63194018C>T	gnomAD
rs1368827241	p.Glu85Asp	missense variant	-	NC_000017.11:g.63194034G>T	gnomAD
NCI-TCGA novel	p.Glu85LeuPheSerTerUnk	frameshift	-	NC_000017.11:g.63194030_63194031insCC	NCI-TCGA
rs780001108	p.Ala86Thr	missense variant	-	NC_000017.11:g.63194035G>A	TOPMed,gnomAD
rs760975964	p.Leu90Ile	missense variant	-	NC_000017.11:g.63194047C>A	ExAC,TOPMed,gnomAD
rs764388206	p.Leu90His	missense variant	-	NC_000017.11:g.63194048T>A	ExAC,gnomAD
rs1434782515	p.Met91Thr	missense variant	-	NC_000017.11:g.63194051T>C	TOPMed
rs1216857524	p.Arg93Cys	missense variant	-	NC_000017.11:g.63194056C>T	TOPMed,gnomAD
rs1017318392	p.Arg93His	missense variant	-	NC_000017.11:g.63194057G>A	TOPMed,gnomAD
rs1340900917	p.Gly95Ser	missense variant	-	NC_000017.11:g.63194062G>A	gnomAD
rs1024277687	p.Leu98Ile	missense variant	-	NC_000017.11:g.63194071C>A	TOPMed
rs1234548944	p.Gly99Arg	missense variant	-	NC_000017.11:g.63194074G>A	TOPMed,gnomAD
rs1234548944	p.Gly99Arg	missense variant	-	NC_000017.11:g.63194074G>C	TOPMed,gnomAD
rs374177469	p.Lys101Thr	missense variant	-	NC_000017.11:g.63194081A>C	ESP,ExAC,TOPMed,gnomAD
rs1189184480	p.Lys101Asn	missense variant	-	NC_000017.11:g.63194082A>T	TOPMed
rs1480699706	p.Lys101Glu	missense variant	-	NC_000017.11:g.63194080A>G	TOPMed
rs1440342044	p.Thr103Ala	missense variant	-	NC_000017.11:g.63194086A>G	TOPMed,gnomAD
rs1209090765	p.Glu104Ala	missense variant	-	NC_000017.11:g.63194090A>C	gnomAD
rs1186640212	p.Val105Gly	missense variant	-	NC_000017.11:g.63194093T>G	gnomAD
rs1486784756	p.Val105Phe	missense variant	-	NC_000017.11:g.63194092G>T	gnomAD
rs750587271	p.Gly108Ser	missense variant	-	NC_000017.11:g.63194101G>A	ExAC,gnomAD
rs1174496373	p.Asp109Tyr	missense variant	-	NC_000017.11:g.63194104G>T	gnomAD
rs542076646	p.Gln110Glu	missense variant	-	NC_000017.11:g.63194107C>G	1000Genomes,ExAC,TOPMed,gnomAD
rs542076646	p.Gln110Lys	missense variant	-	NC_000017.11:g.63194107C>A	1000Genomes,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Tyr111Ter	stop gained	-	NC_000017.11:g.63194112C>A	NCI-TCGA
rs368358169	p.Ser112Asn	missense variant	-	NC_000017.11:g.63194114G>A	ESP,ExAC,TOPMed,gnomAD
rs755920448	p.Met113Arg	missense variant	-	NC_000017.11:g.63194117T>G	ExAC,gnomAD
rs1319198280	p.Gln116Leu	missense variant	-	NC_000017.11:g.63194126A>T	gnomAD
rs1440917384	p.Gln120Arg	missense variant	-	NC_000017.11:g.63194138A>G	gnomAD
rs766584396	p.Thr121Ala	missense variant	-	NC_000017.11:g.63200771A>G	ExAC,gnomAD
rs755191740	p.Arg127Trp	missense variant	-	NC_000017.11:g.63200789C>T	ExAC,gnomAD
rs371507266	p.Arg127Gln	missense variant	-	NC_000017.11:g.63200790G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1292082774	p.Ile128Val	missense variant	-	NC_000017.11:g.63200792A>G	gnomAD
COSM982507	p.Ser129Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63200797T>A	NCI-TCGA Cosmic
rs753644514	p.Thr133Ile	missense variant	-	NC_000017.11:g.63200808C>T	ExAC,gnomAD
rs376672390	p.Ser136Gly	missense variant	-	NC_000017.11:g.63200816A>G	ESP,ExAC,gnomAD
rs745832485	p.Ser137Asn	missense variant	-	NC_000017.11:g.63200820G>A	ExAC,gnomAD
rs779580541	p.Thr138Ile	missense variant	-	NC_000017.11:g.63200823C>T	ExAC
NCI-TCGA novel	p.Thr138Ala	missense variant	-	NC_000017.11:g.63200822A>G	NCI-TCGA
rs757864126	p.Thr138Pro	missense variant	-	NC_000017.11:g.63200822A>C	ExAC
rs746643663	p.Ala139Ser	missense variant	-	NC_000017.11:g.63200825G>T	ExAC
rs1180406160	p.Ala139Val	missense variant	-	NC_000017.11:g.63200826C>T	gnomAD
rs781614403	p.Ser140Pro	missense variant	-	NC_000017.11:g.63200828T>C	ExAC
COSM4822522	p.Ser140Cys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63200829C>G	NCI-TCGA Cosmic
rs770207350	p.Pro141Leu	missense variant	-	NC_000017.11:g.63200832C>T	ExAC,gnomAD
rs774620189	p.Cys147Tyr	missense variant	-	NC_000017.11:g.63200850G>A	ExAC,gnomAD
rs759802007	p.Ser148Cys	missense variant	-	NC_000017.11:g.63200853C>G	ExAC,TOPMed,gnomAD
rs767571631	p.Thr149Ala	missense variant	-	NC_000017.11:g.63200855A>G	ExAC,gnomAD
rs1355902651	p.Pro152Arg	missense variant	-	NC_000017.11:g.63200865C>G	TOPMed,gnomAD
rs117690040	p.Ile153Thr	missense variant	-	NC_000017.11:g.63200868T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1235044719	p.Ile153Val	missense variant	-	NC_000017.11:g.63200867A>G	gnomAD
rs117690040	p.Ile153Ser	missense variant	-	NC_000017.11:g.63200868T>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1355559251	p.Ser154Asn	missense variant	-	NC_000017.11:g.63200871G>A	TOPMed,gnomAD
NCI-TCGA novel	p.Thr155Lys	missense variant	-	NC_000017.11:g.63200874C>A	NCI-TCGA
rs372846249	p.Ala157Glu	missense variant	-	NC_000017.11:g.63200880C>A	ESP,ExAC,TOPMed,gnomAD
rs1209255352	p.Ala157Thr	missense variant	-	NC_000017.11:g.63200879G>A	gnomAD
rs201042925	p.Thr158Ala	missense variant	-	NC_000017.11:g.63200882A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs750331255	p.Ala159Val	missense variant	-	NC_000017.11:g.63200886C>T	ExAC,gnomAD
rs1419078798	p.Lys160Glu	missense variant	-	NC_000017.11:g.63200888A>G	TOPMed
rs375435674	p.Asp161Asn	missense variant	-	NC_000017.11:g.63200891G>A	ESP,ExAC,gnomAD
rs1206638765	p.Ser163Thr	missense variant	-	NC_000017.11:g.63200898G>C	TOPMed,gnomAD
rs1190217186	p.Tyr164His	missense variant	-	NC_000017.11:g.63200900T>C	gnomAD
rs1253248206	p.Gly165Ala	missense variant	-	NC_000017.11:g.63200904G>C	TOPMed,gnomAD
COSM2794558	p.Gly165Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63200904G>A	NCI-TCGA Cosmic
rs201520197	p.Ala166Pro	missense variant	-	NC_000017.11:g.63200906G>C	1000Genomes,ExAC,TOPMed,gnomAD
COSM4068513	p.Ala166Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63200907C>T	NCI-TCGA Cosmic
rs201520197	p.Ala166Ser	missense variant	-	NC_000017.11:g.63200906G>T	1000Genomes,ExAC,TOPMed,gnomAD
rs1472767516	p.Thr168Ile	missense variant	-	NC_000017.11:g.63200913C>T	gnomAD
rs1028077442	p.Ser169Gly	missense variant	-	NC_000017.11:g.63200915A>G	TOPMed
COSM3520592	p.Pro170Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63200918C>T	NCI-TCGA Cosmic
rs1371904597	p.Thr171Ser	missense variant	-	NC_000017.11:g.63200921A>T	gnomAD
rs1371904597	p.Thr171Ala	missense variant	-	NC_000017.11:g.63200921A>G	gnomAD
rs1323298996	p.Thr171Asn	missense variant	-	NC_000017.11:g.63200922C>A	TOPMed
NCI-TCGA novel	p.Arg177Thr	missense variant	-	NC_000017.11:g.63200940G>C	NCI-TCGA
rs747858720	p.Arg177Lys	missense variant	-	NC_000017.11:g.63200940G>A	ExAC,gnomAD
rs1344818284	p.Thr186Ser	missense variant	-	NC_000017.11:g.63237822A>T	gnomAD
rs1209899492	p.Ser187Asn	missense variant	-	NC_000017.11:g.63237826G>A	TOPMed,gnomAD
rs1209899492	p.Ser187Thr	missense variant	-	NC_000017.11:g.63237826G>C	TOPMed,gnomAD
rs755877273	p.Ser189Cys	missense variant	-	NC_000017.11:g.63237832C>G	ExAC,TOPMed,gnomAD
rs755877273	p.Ser189Tyr	missense variant	-	NC_000017.11:g.63237832C>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asn191LysPheSerTerUnkUnk	frameshift	-	NC_000017.11:g.63237834_63237835insA	NCI-TCGA
rs1188923003	p.Val192Leu	missense variant	-	NC_000017.11:g.63237840G>T	TOPMed
rs144412511	p.Arg194His	missense variant	-	NC_000017.11:g.63237847G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs377601940	p.Arg194Cys	missense variant	-	NC_000017.11:g.63237846C>T	ESP,ExAC,TOPMed,gnomAD
rs564167660	p.Lys196Gln	missense variant	-	NC_000017.11:g.63237852A>C	1000Genomes,ExAC,gnomAD
rs1196364888	p.Ala198Ser	missense variant	-	NC_000017.11:g.63237858G>T	gnomAD
rs746422304	p.Gly199Glu	missense variant	-	NC_000017.11:g.63237862G>A	ExAC,TOPMed,gnomAD
rs1264414343	p.Glu200Asp	missense variant	-	NC_000017.11:g.63237866A>C	TOPMed
rs1242004650	p.Ser201Gly	missense variant	-	NC_000017.11:g.63237867A>G	TOPMed
rs1454183238	p.Ser201Ile	missense variant	-	NC_000017.11:g.63237868G>T	gnomAD
rs1161108951	p.Ser202Gly	missense variant	-	NC_000017.11:g.63237870A>G	gnomAD
COSM4835355	p.Gly209Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63237892G>A	NCI-TCGA Cosmic
rs549495715	p.Asn210Ile	missense variant	-	NC_000017.11:g.63237895A>T	1000Genomes,ExAC,gnomAD
rs775688847	p.Ile211Val	missense variant	-	NC_000017.11:g.63237897A>G	ExAC,gnomAD
rs1368453607	p.Ile211Met	missense variant	-	NC_000017.11:g.63237899A>G	gnomAD
rs747187471	p.Lys212Gln	missense variant	-	NC_000017.11:g.63237900A>C	ExAC,gnomAD
rs1299545972	p.Pro213Thr	missense variant	-	NC_000017.11:g.63237903C>A	gnomAD
rs1229328527	p.Trp214Cys	missense variant	-	NC_000017.11:g.63237908G>T	gnomAD
rs762674905	p.Gln215Lys	missense variant	-	NC_000017.11:g.63237909C>A	ExAC,gnomAD
rs1208696125	p.Ser219Cys	missense variant	-	NC_000017.11:g.63237922C>G	gnomAD
NCI-TCGA novel	p.Ser220ThrPheSerTerUnkUnk	frameshift	-	NC_000017.11:g.63237922_63237923insAACTCAAGATA	NCI-TCGA
rs1265491241	p.Ser220Gly	missense variant	-	NC_000017.11:g.63237924A>G	gnomAD
rs1189097027	p.Met221Thr	missense variant	-	NC_000017.11:g.63237928T>C	gnomAD
rs201315770	p.Met221Val	missense variant	-	NC_000017.11:g.63237927A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1318746309	p.Ser223Phe	missense variant	-	NC_000017.11:g.63237934C>T	TOPMed
rs759558896	p.Cys224Ser	missense variant	-	NC_000017.11:g.63237937G>C	ExAC,TOPMed,gnomAD
rs1391526265	p.Tyr226Cys	missense variant	-	NC_000017.11:g.63237943A>G	TOPMed
rs1409531518	p.Arg227Gln	missense variant	-	NC_000017.11:g.63237946G>A	gnomAD
NCI-TCGA novel	p.Arg227Ter	stop gained	-	NC_000017.11:g.63237945C>T	NCI-TCGA
rs1292956002	p.Val228Ala	missense variant	-	NC_000017.11:g.63237949T>C	TOPMed
rs1372278222	p.Asn231Ile	missense variant	-	NC_000017.11:g.63237958A>T	TOPMed
rs763783613	p.Ala234Pro	missense variant	-	NC_000017.11:g.63237966G>C	ExAC,gnomAD
rs548539914	p.Thr236Ser	missense variant	-	NC_000017.11:g.63237973C>G	1000Genomes,ExAC,gnomAD
rs1459446240	p.Thr236Ala	missense variant	-	NC_000017.11:g.63237972A>G	gnomAD
rs757656357	p.Tyr237Cys	missense variant	-	NC_000017.11:g.63237976A>G	ExAC,TOPMed,gnomAD
rs1448615712	p.Ser238Arg	missense variant	-	NC_000017.11:g.63237980T>G	TOPMed
rs1290562918	p.Asn240Ser	missense variant	-	NC_000017.11:g.63237985A>G	gnomAD
rs779376027	p.Ile242Phe	missense variant	-	NC_000017.11:g.63237990A>T	ExAC
rs370972389	p.Pro243Leu	missense variant	-	NC_000017.11:g.63237994C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1314150006	p.Glu244Lys	missense variant	-	NC_000017.11:g.63237996G>A	gnomAD
rs1200536468	p.Glu244Val	missense variant	-	NC_000017.11:g.63237997A>T	TOPMed
rs779995743	p.Glu244Asp	missense variant	-	NC_000017.11:g.63237998G>T	ExAC,gnomAD
rs375527040	p.Arg245Lys	missense variant	-	NC_000017.11:g.63238000G>A	ESP,ExAC,TOPMed,gnomAD
rs1264374457	p.Leu247Ser	missense variant	-	NC_000017.11:g.63238006T>C	TOPMed,gnomAD
rs768734001	p.Thr249Ile	missense variant	-	NC_000017.11:g.63238012C>T	ExAC,TOPMed,gnomAD
rs1182234949	p.Gln253Arg	missense variant	-	NC_000017.11:g.63238024A>G	gnomAD
rs748397247	p.Ser254Ala	missense variant	-	NC_000017.11:g.63238026T>G	ExAC,gnomAD
NCI-TCGA novel	p.Gln256Leu	missense variant	-	NC_000017.11:g.63238033A>T	NCI-TCGA
rs1321681097	p.Ile258Val	missense variant	-	NC_000017.11:g.63238038A>G	TOPMed,gnomAD
rs534965097	p.Met263Ile	missense variant	-	NC_000017.11:g.63238055G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs767556585	p.Met263Val	missense variant	-	NC_000017.11:g.63238053A>G	ExAC,gnomAD
rs534965097	p.Met263Ile	missense variant	-	NC_000017.11:g.63238055G>C	1000Genomes,ExAC,TOPMed,gnomAD
rs760215311	p.Arg265Trp	missense variant	-	NC_000017.11:g.63238059C>T	ExAC,TOPMed,gnomAD
rs1235906366	p.Arg265Gln	missense variant	-	NC_000017.11:g.63238060G>A	TOPMed
rs1178990187	p.His276Arg	missense variant	-	NC_000017.11:g.63267763A>G	TOPMed
rs778567291	p.Asp279Gly	missense variant	-	NC_000017.11:g.63267772A>G	ExAC,gnomAD
rs898876116	p.Ala281Thr	missense variant	-	NC_000017.11:g.63267777G>A	TOPMed
rs1162654174	p.Tyr282Cys	missense variant	-	NC_000017.11:g.63267781A>G	gnomAD
rs745608593	p.Asp284Gly	missense variant	-	NC_000017.11:g.63267787A>G	ExAC,gnomAD
rs1475191387	p.Gln286Glu	missense variant	-	NC_000017.11:g.63267792C>G	gnomAD
rs370855180	p.Gln286Arg	missense variant	-	NC_000017.11:g.63267793A>G	ESP,ExAC,TOPMed,gnomAD
rs1486492513	p.Arg287Thr	missense variant	-	NC_000017.11:g.63267796G>C	TOPMed
rs373961923	p.His288Arg	missense variant	-	NC_000017.11:g.63267799A>G	ESP,ExAC,TOPMed,gnomAD
rs776342589	p.Thr289Pro	missense variant	-	NC_000017.11:g.63267801A>C	ExAC,gnomAD
rs761556714	p.Thr289Ile	missense variant	-	NC_000017.11:g.63267802C>T	ExAC,gnomAD
NCI-TCGA novel	p.Thr289Ala	missense variant	-	NC_000017.11:g.63267801A>G	NCI-TCGA
rs764880643	p.Pro290Ala	missense variant	-	NC_000017.11:g.63267804C>G	ExAC,gnomAD
COSM706524	p.Ser294Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63267817C>T	NCI-TCGA Cosmic
COSM1385110	p.Ser294Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63267817C>A	NCI-TCGA Cosmic
rs763326514	p.Arg296Gln	missense variant	-	NC_000017.11:g.63267823G>A	ExAC,gnomAD
rs766681632	p.Met297Val	missense variant	-	NC_000017.11:g.63267825A>G	ExAC,gnomAD
rs752026592	p.Pro298Ala	missense variant	-	NC_000017.11:g.63267828C>G	ExAC,TOPMed,gnomAD
COSM982511	p.Pro298Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63267828C>T	NCI-TCGA Cosmic
rs755523835	p.Arg299Ser	missense variant	-	NC_000017.11:g.63267833A>T	ExAC,gnomAD
rs1268551911	p.Gln300Lys	missense variant	-	NC_000017.11:g.63267834C>A	gnomAD
rs1268551911	p.Gln300Glu	missense variant	-	NC_000017.11:g.63267834C>G	gnomAD
rs944064015	p.Gly303Asp	missense variant	-	NC_000017.11:g.63267844G>A	TOPMed,gnomAD
rs756151305	p.Arg306Leu	missense variant	-	NC_000017.11:g.63267853G>T	ExAC,TOPMed,gnomAD
rs756151305	p.Arg306His	missense variant	-	NC_000017.11:g.63267853G>A	ExAC,TOPMed,gnomAD
rs752840067	p.Arg306Cys	missense variant	-	NC_000017.11:g.63267852C>T	ExAC,TOPMed,gnomAD
rs1440480178	p.Thr307Pro	missense variant	-	NC_000017.11:g.63267855A>C	TOPMed
rs774755576	p.Arg314His	missense variant	-	NC_000017.11:g.63314391G>A	ExAC,TOPMed,gnomAD
rs766703437	p.Arg314Cys	missense variant	-	NC_000017.11:g.63314390C>T	ExAC,TOPMed,gnomAD
rs1356974520	p.Phe315Ser	missense variant	-	NC_000017.11:g.63314394T>C	gnomAD
rs760032068	p.Ala316Val	missense variant	-	NC_000017.11:g.63314397C>T	ExAC,TOPMed,gnomAD
rs373599249	p.Pro317Ser	missense variant	-	NC_000017.11:g.63314399C>T	ESP,ExAC,gnomAD
NCI-TCGA novel	p.Pro317Leu	missense variant	-	NC_000017.11:g.63314400C>T	NCI-TCGA
NCI-TCGA novel	p.Pro317Thr	missense variant	-	NC_000017.11:g.63314399C>A	NCI-TCGA
rs1450050054	p.Arg319Thr	missense variant	-	NC_000017.11:g.63314406G>C	gnomAD
rs188282938	p.Pro321Ala	missense variant	-	NC_000017.11:g.63314411C>G	1000Genomes
rs756181350	p.Asp322Gly	missense variant	-	NC_000017.11:g.63314415A>G	ExAC,gnomAD
rs764122149	p.Ile323Thr	missense variant	-	NC_000017.11:g.63314418T>C	ExAC,gnomAD
COSM6147668	p.Ile323Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63314417A>G	NCI-TCGA Cosmic
rs565290187	p.Pro327Ala	missense variant	-	NC_000017.11:g.63314429C>G	1000Genomes,ExAC,gnomAD
rs575715567	p.Val332Met	missense variant	-	NC_000017.11:g.63314444G>A	1000Genomes
rs779994723	p.Pro333Arg	missense variant	-	NC_000017.11:g.63314448C>G	ExAC
rs754837305	p.Ile335Val	missense variant	-	NC_000017.11:g.63314453A>G	ExAC,gnomAD
rs781229986	p.Ile335Met	missense variant	-	NC_000017.11:g.63314455C>G	ExAC,gnomAD
rs1308322956	p.Thr336Ile	missense variant	-	NC_000017.11:g.63314457C>T	gnomAD
NCI-TCGA novel	p.Glu338Ter	stop gained	-	NC_000017.11:g.63314462G>T	NCI-TCGA
COSM3820169	p.Glu338Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63314462G>C	NCI-TCGA Cosmic
COSM982516	p.Phe341Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63314472T>C	NCI-TCGA Cosmic
rs749094947	p.Arg344Gln	missense variant	-	NC_000017.11:g.63314481G>A	ExAC,TOPMed,gnomAD
rs772644087	p.Trp346Arg	missense variant	-	NC_000017.11:g.63314486T>A	ExAC,gnomAD
rs367733202	p.Phe348Tyr	missense variant	-	NC_000017.11:g.63314493T>A	ESP,ExAC,gnomAD
rs773996052	p.Glu350Lys	missense variant	-	NC_000017.11:g.63314498G>A	ExAC,TOPMed,gnomAD
rs887084046	p.Ile351Thr	missense variant	-	NC_000017.11:g.63314502T>C	TOPMed,gnomAD
rs759835968	p.Asp352Val	missense variant	-	NC_000017.11:g.63314505A>T	ExAC,gnomAD
rs767889438	p.Asp352Glu	missense variant	-	NC_000017.11:g.63314506T>A	ExAC,gnomAD
rs1397456251	p.Ala353Val	missense variant	-	NC_000017.11:g.63314508C>T	TOPMed
rs776036126	p.Gln354His	missense variant	-	NC_000017.11:g.63314512A>T	ExAC,TOPMed,gnomAD
rs1190283777	p.Gln356Lys	missense variant	-	NC_000017.11:g.63314516C>A	gnomAD
rs761135261	p.Ser357Ile	missense variant	-	NC_000017.11:g.63314520G>T	ExAC,TOPMed,gnomAD
rs761135261	p.Ser357Asn	missense variant	-	NC_000017.11:g.63314520G>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ser358Pro	missense variant	-	NC_000017.11:g.63314522T>C	NCI-TCGA
rs764221772	p.Asn359Ser	missense variant	-	NC_000017.11:g.63314526A>G	ExAC,gnomAD
rs1168683428	p.Ala360Thr	missense variant	-	NC_000017.11:g.63314528G>A	TOPMed,gnomAD
rs1391576299	p.Ser361Thr	missense variant	-	NC_000017.11:g.63314532G>C	TOPMed,gnomAD
rs757422430	p.Val362Met	missense variant	-	NC_000017.11:g.63314534G>A	ExAC,TOPMed,gnomAD
rs750699899	p.Val366Ile	missense variant	-	NC_000017.11:g.63314546G>A	ExAC,TOPMed,gnomAD
rs774309244	p.Val367Leu	missense variant	-	NC_000017.11:g.63314549G>C	ExAC,TOPMed,gnomAD
COSM5178865	p.Val367Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63314550T>C	NCI-TCGA Cosmic
rs774309244	p.Val367Met	missense variant	-	NC_000017.11:g.63314549G>A	ExAC,TOPMed,gnomAD
rs1298452004	p.Ile368Val	missense variant	-	NC_000017.11:g.63314552A>G	gnomAD
rs756060797	p.Val369Met	missense variant	-	NC_000017.11:g.63314555G>A	ExAC,gnomAD
NCI-TCGA novel	p.Gly370Glu	missense variant	-	NC_000017.11:g.63314559G>A	NCI-TCGA
NCI-TCGA novel	p.Asn371Ser	missense variant	-	NC_000017.11:g.63314562A>G	NCI-TCGA
rs1461277488	p.Ala378Gly	missense variant	-	NC_000017.11:g.63314583C>G	gnomAD
rs150364213	p.Ile379Val	missense variant	-	NC_000017.11:g.63314585A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs964160016	p.Ile380Val	missense variant	-	NC_000017.11:g.63314588A>G	TOPMed,gnomAD
rs745560986	p.Leu386Val	missense variant	-	NC_000017.11:g.63314606C>G	ExAC,gnomAD
rs775775457	p.Ser387Asn	missense variant	-	NC_000017.11:g.63314610G>A	ExAC,gnomAD
rs1170607520	p.His389Arg	missense variant	-	NC_000017.11:g.63314616A>G	gnomAD
rs1450898417	p.Gly390Arg	missense variant	-	NC_000017.11:g.63314618G>C	TOPMed
rs761240810	p.Thr391Arg	missense variant	-	NC_000017.11:g.63314622C>G	ExAC,gnomAD
rs1321266433	p.Met393Leu	missense variant	-	NC_000017.11:g.63314627A>T	gnomAD
rs1295212416	p.Ala397Ser	missense variant	-	NC_000017.11:g.63314639G>T	gnomAD
COSM982518	p.Ala397Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63314639G>A	NCI-TCGA Cosmic
rs1334014676	p.Ala397Val	missense variant	-	NC_000017.11:g.63314640C>T	TOPMed
rs369559231	p.Asp399Gly	missense variant	-	NC_000017.11:g.63314646A>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Pro401Ala	missense variant	-	NC_000017.11:g.63314651C>G	NCI-TCGA
COSM3520596	p.Pro401Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63314652C>T	NCI-TCGA Cosmic
rs765441426	p.Pro405Arg	missense variant	-	NC_000017.11:g.63314664C>G	ExAC,TOPMed,gnomAD
rs765441426	p.Pro405His	missense variant	-	NC_000017.11:g.63314664C>A	ExAC,TOPMed,gnomAD
rs1323407265	p.Pro405Ala	missense variant	-	NC_000017.11:g.63314663C>G	gnomAD
rs372517614	p.His407Tyr	missense variant	-	NC_000017.11:g.63314669C>T	ESP,ExAC,TOPMed,gnomAD
rs372517614	p.His407Asn	missense variant	-	NC_000017.11:g.63314669C>A	ESP,ExAC,TOPMed,gnomAD
rs1184703786	p.Val408Met	missense variant	-	NC_000017.11:g.63318959G>A	TOPMed
rs200724320	p.Asp409Val	missense variant	-	NC_000017.11:g.63318963A>T	ESP,ExAC,TOPMed,gnomAD
rs200724320	p.Asp409Gly	missense variant	-	NC_000017.11:g.63318963A>G	ESP,ExAC,TOPMed,gnomAD
rs769969806	p.Asp409Asn	missense variant	-	NC_000017.11:g.63318962G>A	ExAC,TOPMed,gnomAD
rs763259864	p.Asn411Tyr	missense variant	-	NC_000017.11:g.63318968A>T	ExAC,TOPMed,gnomAD
rs1418458184	p.Asn411Ile	missense variant	-	NC_000017.11:g.63318969A>T	gnomAD
rs766443905	p.Glu413Asp	missense variant	-	NC_000017.11:g.63318976G>C	ExAC,TOPMed,gnomAD
rs1365191835	p.Leu416Pro	missense variant	-	NC_000017.11:g.63318984T>C	gnomAD
rs763979750	p.Leu416Phe	missense variant	-	NC_000017.11:g.63318983C>T	ExAC,gnomAD
rs577705394	p.Thr417Ser	missense variant	-	NC_000017.11:g.63318986A>T	ExAC,gnomAD
rs577705394	p.Thr417Ala	missense variant	-	NC_000017.11:g.63318986A>G	ExAC,gnomAD
rs1371758873	p.Pro419Leu	missense variant	-	NC_000017.11:g.63318993C>T	gnomAD
rs778390901	p.Pro420Arg	missense variant	-	NC_000017.11:g.63318996C>G	ExAC,gnomAD
NCI-TCGA novel	p.Ser421Leu	missense variant	-	NC_000017.11:g.63318999C>T	NCI-TCGA
rs749869278	p.Ala422Val	missense variant	-	NC_000017.11:g.63319002C>T	ExAC,TOPMed,gnomAD
rs376018871	p.His423Leu	missense variant	-	NC_000017.11:g.63319005A>T	ESP,ExAC,TOPMed,gnomAD
rs369292271	p.Ser424Leu	missense variant	-	NC_000017.11:g.63319008C>T	ESP,ExAC,TOPMed,gnomAD
rs753217237	p.Ile426Val	missense variant	-	NC_000017.11:g.63319013A>G	ExAC,TOPMed,gnomAD
rs768874285	p.Ser428Asn	missense variant	-	NC_000017.11:g.63319020G>A	ExAC
COSM3520598	p.Thr434Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63319037A>G	NCI-TCGA Cosmic
rs1386169242	p.Pro435Leu	missense variant	-	NC_000017.11:g.63319041C>T	TOPMed
COSM706519	p.Glu436Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63319043G>A	NCI-TCGA Cosmic
rs1480252971	p.Arg438Cys	missense variant	-	NC_000017.11:g.63319049C>T	gnomAD
rs770485904	p.Arg438Leu	missense variant	-	NC_000017.11:g.63319050G>T	ExAC,TOPMed,gnomAD
rs770485904	p.Arg438His	missense variant	-	NC_000017.11:g.63319050G>A	ExAC,TOPMed,gnomAD
rs199541150	p.Arg440Trp	missense variant	-	NC_000017.11:g.63319055C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs778411760	p.Arg440Gln	missense variant	-	NC_000017.11:g.63319056G>A	ExAC,TOPMed,gnomAD
rs1250494970	p.Gln441Lys	missense variant	-	NC_000017.11:g.63319058C>A	TOPMed
COSM3692009	p.Glu442Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63319063G>T	NCI-TCGA Cosmic
rs774394103	p.Met445Val	missense variant	-	NC_000017.11:g.63319070A>G	ExAC,gnomAD
rs1170839144	p.Met445Ile	missense variant	-	NC_000017.11:g.63319072G>A	gnomAD
rs1353171827	p.Arg446Gly	missense variant	-	NC_000017.11:g.63319073C>G	gnomAD
COSM5138367	p.Arg446Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63319073C>T	NCI-TCGA Cosmic
rs202242128	p.Arg446Gln	missense variant	-	NC_000017.11:g.63319074G>A	ESP,ExAC,TOPMed,gnomAD
rs554015043	p.Leu448Pro	missense variant	-	NC_000017.11:g.63319080T>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ala449Val	missense variant	-	NC_000017.11:g.63319083C>T	NCI-TCGA
rs750275507	p.Ser450Leu	missense variant	-	NC_000017.11:g.63319086C>T	ExAC,gnomAD
rs1321365646	p.Val452Leu	missense variant	-	NC_000017.11:g.63340101G>C	gnomAD
rs773104858	p.Val453Ile	missense variant	-	NC_000017.11:g.63340104G>A	ExAC,gnomAD
rs763000493	p.Ala454Val	missense variant	-	NC_000017.11:g.63340108C>T	ExAC,gnomAD
rs376257499	p.Tyr455Cys	missense variant	-	NC_000017.11:g.63340111A>G	ESP,ExAC,TOPMed,gnomAD
rs745539155	p.Tyr457Ser	missense variant	-	NC_000017.11:g.63340117A>C	ExAC,TOPMed,gnomAD
rs745539155	p.Tyr457Cys	missense variant	-	NC_000017.11:g.63340117A>G	ExAC,TOPMed,gnomAD
rs1475194628	p.Asp461Glu	missense variant	-	NC_000017.11:g.63340130T>A	gnomAD
rs1192176613	p.Asn462Ser	missense variant	-	NC_000017.11:g.63340132A>G	gnomAD
rs1379360999	p.Pro469Leu	missense variant	-	NC_000017.11:g.63340153C>T	TOPMed
rs1176260039	p.His473Arg	missense variant	-	NC_000017.11:g.63340165A>G	gnomAD
rs886689708	p.Asn474Ser	missense variant	-	NC_000017.11:g.63340168A>G	TOPMed,gnomAD
rs752419482	p.Val475Ile	missense variant	-	NC_000017.11:g.63340170G>A	ExAC,gnomAD
rs1343347708	p.Leu479Phe	missense variant	-	NC_000017.11:g.63340182C>T	gnomAD
rs200481329	p.Arg481His	missense variant	-	NC_000017.11:g.63340189G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs200481329	p.Arg481Leu	missense variant	-	NC_000017.11:g.63340189G>T	1000Genomes,ExAC,TOPMed,gnomAD
rs757851333	p.Arg481Cys	missense variant	-	NC_000017.11:g.63340188C>T	ExAC,gnomAD
rs1016421071	p.Ser482Pro	missense variant	-	NC_000017.11:g.63340191T>C	TOPMed
rs745904981	p.Pro483Leu	missense variant	-	NC_000017.11:g.63340195C>T	ExAC,TOPMed,gnomAD
rs745904981	p.Pro483Arg	missense variant	-	NC_000017.11:g.63340195C>G	ExAC,TOPMed,gnomAD
rs772164592	p.Gln484His	missense variant	-	NC_000017.11:g.63340199G>T	ExAC,gnomAD
rs1221110322	p.Gln484Arg	missense variant	-	NC_000017.11:g.63340198A>G	TOPMed,gnomAD
rs1221110322	p.Gln484Pro	missense variant	-	NC_000017.11:g.63340198A>C	TOPMed,gnomAD
NCI-TCGA novel	p.Arg489Gln	missense variant	-	NC_000017.11:g.63340213G>A	NCI-TCGA
rs1222518321	p.Glu490Asp	missense variant	-	NC_000017.11:g.63340217G>C	gnomAD
rs1271505862	p.Leu492His	missense variant	-	NC_000017.11:g.63340222T>A	gnomAD
rs1489982477	p.Leu493Phe	missense variant	-	NC_000017.11:g.63340224C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Leu493Val	missense variant	-	NC_000017.11:g.63340224C>G	NCI-TCGA
COSM982520	p.Leu493Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63340224C>A	NCI-TCGA Cosmic
rs746776222	p.Arg494Trp	missense variant	-	NC_000017.11:g.63340227C>T	TOPMed
rs780211899	p.Arg494Gln	missense variant	-	NC_000017.11:g.63340228G>A	ExAC,TOPMed,gnomAD
rs746776222	p.Arg494Gly	missense variant	-	NC_000017.11:g.63340227C>G	TOPMed
rs747276639	p.Glu495Lys	missense variant	-	NC_000017.11:g.63340230G>A	ExAC,gnomAD
NCI-TCGA novel	p.Glu495Ter	stop gained	-	NC_000017.11:g.63340230G>T	NCI-TCGA
rs189418855	p.His497Tyr	missense variant	-	NC_000017.11:g.63340236C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs189418855	p.His497Asn	missense variant	-	NC_000017.11:g.63340236C>A	1000Genomes,ExAC,TOPMed,gnomAD
rs762791990	p.Leu498Val	missense variant	-	NC_000017.11:g.63340239C>G	ExAC,TOPMed,gnomAD
rs1237656513	p.Ser500Asn	missense variant	-	NC_000017.11:g.63340246G>A	TOPMed
rs770832810	p.Met501Ile	missense variant	-	NC_000017.11:g.63340250G>A	ExAC,gnomAD
rs759037186	p.Leu504Val	missense variant	-	NC_000017.11:g.63340257C>G	ExAC,gnomAD
rs767165738	p.Arg505Cys	missense variant	-	NC_000017.11:g.63340260C>T	ExAC,gnomAD
rs752366326	p.Arg505His	missense variant	-	NC_000017.11:g.63340261G>A	ExAC,gnomAD
rs764550479	p.Pro511Thr	missense variant	-	NC_000017.11:g.63340278C>A	ExAC,gnomAD
rs754165842	p.Pro511Arg	missense variant	-	NC_000017.11:g.63340279C>G	ExAC,gnomAD
rs199687343	p.Met512Val	missense variant	-	NC_000017.11:g.63340281A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs199687343	p.Met512Leu	missense variant	-	NC_000017.11:g.63340281A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1298564410	p.Met512Lys	missense variant	-	NC_000017.11:g.63340282T>A	TOPMed
rs750928211	p.Ala513Val	missense variant	-	NC_000017.11:g.63340285C>T	ExAC,gnomAD
rs1383716664	p.Ser514Phe	missense variant	-	NC_000017.11:g.63340288C>T	TOPMed
rs140111765	p.Arg516Gln	missense variant	-	NC_000017.11:g.63340294G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs552429950	p.Arg516Trp	missense variant	-	NC_000017.11:g.63340293C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs768930153	p.Arg517Met	missense variant	-	NC_000017.11:g.63340297G>T	ExAC,TOPMed,gnomAD
rs1252944140	p.Val519Ile	missense variant	-	NC_000017.11:g.63340302G>A	gnomAD
COSM982522	p.Leu520Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63340305C>A	NCI-TCGA Cosmic
rs1245874300	p.Glu521Gly	missense variant	-	NC_000017.11:g.63340309A>G	gnomAD
NCI-TCGA novel	p.Glu524Lys	missense variant	-	NC_000017.11:g.63340317G>A	NCI-TCGA
rs966639090	p.Asn525Asp	missense variant	-	NC_000017.11:g.63340320A>G	TOPMed
rs749051087	p.Leu526Ile	missense variant	-	NC_000017.11:g.63340323C>A	ExAC,gnomAD
rs770650572	p.His527Tyr	missense variant	-	NC_000017.11:g.63340326C>T	ExAC,gnomAD
rs1195701426	p.Lys528Arg	missense variant	-	NC_000017.11:g.63340330A>G	TOPMed
rs780099779	p.Asp536Tyr	missense variant	-	NC_000017.11:g.63351270G>T	ExAC,gnomAD
rs1167087436	p.Phe537Leu	missense variant	-	NC_000017.11:g.63351275C>G	gnomAD
rs751568613	p.Ile538Asn	missense variant	-	NC_000017.11:g.63351277T>A	ExAC,gnomAD
rs755062134	p.Ile539Val	missense variant	-	NC_000017.11:g.63351279A>G	ExAC,TOPMed,gnomAD
rs1338809536	p.Leu540Ser	missense variant	-	NC_000017.11:g.63351283T>C	gnomAD
rs987148166	p.Ile541Thr	missense variant	-	NC_000017.11:g.63351286T>C	TOPMed
rs912986449	p.Leu544Val	missense variant	-	NC_000017.11:g.63351294T>G	TOPMed
rs1403928856	p.Glu546Ala	missense variant	-	NC_000017.11:g.63351301A>C	gnomAD
rs748348737	p.Lys551Asn	missense variant	-	NC_000017.11:g.63351317A>C	ExAC,gnomAD
rs1323343392	p.Pro552Leu	missense variant	-	NC_000017.11:g.63351319C>T	gnomAD
rs1328411559	p.Pro552Ala	missense variant	-	NC_000017.11:g.63351318C>G	TOPMed,gnomAD
COSM437095	p.Asp553Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63351321G>T	NCI-TCGA Cosmic
rs1269945617	p.Tyr554Cys	missense variant	-	NC_000017.11:g.63351325A>G	gnomAD
rs368614050	p.Tyr554His	missense variant	-	NC_000017.11:g.63351324T>C	ESP,ExAC,TOPMed,gnomAD
rs372829353	p.Ile558Val	missense variant	-	NC_000017.11:g.63351336A>G	ESP,ExAC,TOPMed,gnomAD
rs201947596	p.Val559Leu	missense variant	-	NC_000017.11:g.63351339G>C	1000Genomes,ExAC,TOPMed,gnomAD
rs775581769	p.Ser560Leu	missense variant	-	NC_000017.11:g.63351343C>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Leu562Pro	missense variant	-	NC_000017.11:g.63351349T>C	NCI-TCGA
rs1263473049	p.Ser563Asn	missense variant	-	NC_000017.11:g.63351352G>A	gnomAD
rs768083183	p.Lys564Glu	missense variant	-	NC_000017.11:g.63351354A>G	ExAC,gnomAD
rs768083183	p.Lys564Gln	missense variant	-	NC_000017.11:g.63351354A>C	ExAC,gnomAD
COSM3520600	p.Met565Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63351359G>A	NCI-TCGA Cosmic
rs371685807	p.Gly567Arg	missense variant	-	NC_000017.11:g.63351363G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs752081450	p.Ile576Thr	missense variant	-	NC_000017.11:g.63351391T>C	ExAC,gnomAD
rs766809764	p.Ile576Leu	missense variant	-	NC_000017.11:g.63351390A>C	ExAC,gnomAD
rs978474288	p.Val577Leu	missense variant	-	NC_000017.11:g.63351393G>T	TOPMed,gnomAD
rs978474288	p.Val577Leu	missense variant	-	NC_000017.11:g.63351393G>C	TOPMed,gnomAD
NCI-TCGA novel	p.Arg580Lys	missense variant	-	NC_000017.11:g.63351403G>A	NCI-TCGA
rs376258048	p.Thr581Asn	missense variant	-	NC_000017.11:g.63351406C>A	ESP,ExAC,TOPMed,gnomAD
rs760007485	p.Thr587Ile	missense variant	-	NC_000017.11:g.63354790C>T	ExAC,gnomAD
rs752785799	p.Pro591Leu	missense variant	-	NC_000017.11:g.63354802C>T	ExAC,gnomAD
rs764173544	p.Phe592Leu	missense variant	-	NC_000017.11:g.63354806C>G	ExAC,TOPMed,gnomAD
rs745661784	p.Phe592Leu	missense variant	-	NC_000017.11:g.63354804T>C	ExAC,TOPMed,gnomAD
rs754146581	p.His593Tyr	missense variant	-	NC_000017.11:g.63354807C>T	ExAC,gnomAD
rs369730989	p.His593Arg	missense variant	-	NC_000017.11:g.63354808A>G	ESP,ExAC,TOPMed,gnomAD
rs1376199676	p.Ile595Val	missense variant	-	NC_000017.11:g.63354813A>G	TOPMed
NCI-TCGA novel	p.Phe596Val	missense variant	-	NC_000017.11:g.63354816T>G	NCI-TCGA
rs751532229	p.Leu597Phe	missense variant	-	NC_000017.11:g.63354821G>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Leu597PhePheSerTerUnk	frameshift	-	NC_000017.11:g.63354813_63354814insT	NCI-TCGA
COSM4732099	p.Leu597TrpPheSerTerUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63354814T>-	NCI-TCGA Cosmic
rs754942145	p.Arg599Gln	missense variant	-	NC_000017.11:g.63354826G>A	ExAC,TOPMed,gnomAD
COSM982528	p.Arg599Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63354825C>T	NCI-TCGA Cosmic
rs1049324972	p.Glu601Lys	missense variant	-	NC_000017.11:g.63354831G>A	TOPMed,gnomAD
rs1181153697	p.Glu602Gly	missense variant	-	NC_000017.11:g.63354835A>G	gnomAD
COSM4817594	p.Glu602Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63354836G>C	NCI-TCGA Cosmic
rs1417474251	p.Glu602Lys	missense variant	-	NC_000017.11:g.63354834G>A	gnomAD
rs769364345	p.Asn603Lys	missense variant	-	NC_000017.11:g.63354839T>A	ExAC,TOPMed,gnomAD
rs1420750947	p.Asn603Ser	missense variant	-	NC_000017.11:g.63354838A>G	TOPMed
rs1426745981	p.Glu604Lys	missense variant	-	NC_000017.11:g.63354840G>A	gnomAD
rs748976038	p.Ile606Val	missense variant	-	NC_000017.11:g.63354846A>G	ExAC,gnomAD
rs1389203603	p.Asp607Glu	missense variant	-	NC_000017.11:g.63354851C>G	gnomAD
rs1462951631	p.Gln608Lys	missense variant	-	NC_000017.11:g.63354852C>A	gnomAD
rs904668924	p.Gln611His	missense variant	-	NC_000017.11:g.63354863G>C	TOPMed,gnomAD
rs889410804	p.Gln611Leu	missense variant	-	NC_000017.11:g.63354862A>T	TOPMed
rs889410804	p.Gln611Arg	missense variant	-	NC_000017.11:g.63354862A>G	TOPMed
rs1315099816	p.Ala612Ser	missense variant	-	NC_000017.11:g.63354864G>T	gnomAD
rs772405958	p.Ala612Val	missense variant	-	NC_000017.11:g.63354865C>T	TOPMed
rs774753696	p.Tyr613Cys	missense variant	-	NC_000017.11:g.63354868A>G	ExAC
rs774753696	p.Tyr613Phe	missense variant	-	NC_000017.11:g.63354868A>T	ExAC
rs1314125287	p.Arg617Gln	missense variant	-	NC_000017.11:g.63354880G>A	gnomAD
rs1243256124	p.Arg617Trp	missense variant	-	NC_000017.11:g.63354879C>T	gnomAD
rs1307789486	p.Ile618Thr	missense variant	-	NC_000017.11:g.63354883T>C	gnomAD
rs772391568	p.His619Tyr	missense variant	-	NC_000017.11:g.63354885C>T	ExAC,TOPMed,gnomAD
rs1040557152	p.Ser620Asn	missense variant	-	NC_000017.11:g.63354889G>A	TOPMed
rs776087632	p.Asn626Ser	missense variant	-	NC_000017.11:g.63354907A>G	ExAC,gnomAD
rs760632609	p.Leu630Phe	missense variant	-	NC_000017.11:g.63354918C>T	ExAC,TOPMed,gnomAD
rs1198128795	p.Gly632Ser	missense variant	-	NC_000017.11:g.63354924G>A	gnomAD
rs764311284	p.Asp635Gly	missense variant	-	NC_000017.11:g.63354934A>G	ExAC,gnomAD
rs900881419	p.Asn636Ser	missense variant	-	NC_000017.11:g.63354937A>G	gnomAD
rs1413342918	p.Thr637Ser	missense variant	-	NC_000017.11:g.63354940C>G	gnomAD
rs1181909409	p.Thr637Ala	missense variant	-	NC_000017.11:g.63354939A>G	TOPMed,gnomAD
rs754093229	p.Thr638Ala	missense variant	-	NC_000017.11:g.63354942A>G	ExAC,TOPMed,gnomAD
rs1290596101	p.Gly640Ser	missense variant	-	NC_000017.11:g.63354948G>A	TOPMed
NCI-TCGA novel	p.Gly640AlaPheSerTerUnkUnk	frameshift	-	NC_000017.11:g.63354948G>-	NCI-TCGA
NCI-TCGA novel	p.Lys641Glu	missense variant	-	NC_000017.11:g.63354951A>G	NCI-TCGA
rs1172961674	p.Leu642Pro	missense variant	-	NC_000017.11:g.63354955T>C	gnomAD
rs1353310697	p.Ser644Phe	missense variant	-	NC_000017.11:g.63354961C>T	gnomAD
rs371351174	p.Lys647Arg	missense variant	-	NC_000017.11:g.63354970A>G	ESP,ExAC,gnomAD
rs766274909	p.Thr648Ser	missense variant	-	NC_000017.11:g.63354972A>T	ExAC,TOPMed,gnomAD
rs766274909	p.Thr648Ala	missense variant	-	NC_000017.11:g.63354972A>G	ExAC,TOPMed,gnomAD
rs754811517	p.Ser653Ala	missense variant	-	NC_000017.11:g.63354987T>G	ExAC,gnomAD
rs997966810	p.Tyr654Cys	missense variant	-	NC_000017.11:g.63354991A>G	TOPMed,gnomAD
COSM982532	p.Leu655Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63354993C>A	NCI-TCGA Cosmic
rs1014962425	p.Leu657Met	missense variant	-	NC_000017.11:g.63354999C>A	TOPMed
NCI-TCGA novel	p.Leu657SerPheSerTerUnk	frameshift	-	NC_000017.11:g.63354997_63354998insT	NCI-TCGA
rs777311411	p.Thr660Ile	missense variant	-	NC_000017.11:g.63355009C>T	ExAC,gnomAD
rs748924735	p.Leu663Ile	missense variant	-	NC_000017.11:g.63355017C>A	ExAC,gnomAD
rs1433118812	p.Ile664Arg	missense variant	-	NC_000017.11:g.63355021T>G	gnomAD
rs778542030	p.Gly667Ser	missense variant	-	NC_000017.11:g.63355029G>A	ExAC,gnomAD
rs772518691	p.Tyr668Cys	missense variant	-	NC_000017.11:g.63355033A>G	ExAC,gnomAD
rs772518691	p.Tyr668Phe	missense variant	-	NC_000017.11:g.63355033A>T	ExAC,gnomAD
COSM4930813	p.Val670Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63355038G>T	NCI-TCGA Cosmic
NCI-TCGA novel	p.Ser674Cys	missense variant	-	NC_000017.11:g.63355051C>G	NCI-TCGA
rs1296754851	p.Val678Ile	missense variant	-	NC_000017.11:g.63355062G>A	TOPMed
rs761295874	p.Val678Ala	missense variant	-	NC_000017.11:g.63355063T>C	ExAC,gnomAD
rs768846086	p.Val679Leu	missense variant	-	NC_000017.11:g.63355065G>C	ExAC,gnomAD
NCI-TCGA novel	p.Val679Ile	missense variant	-	NC_000017.11:g.63355065G>A	NCI-TCGA
rs776921699	p.Ser682Leu	missense variant	-	NC_000017.11:g.63355075C>T	ExAC,gnomAD
COSM4849028	p.Glu685Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63355083G>A	NCI-TCGA Cosmic
NCI-TCGA novel	p.Met693Ile	missense variant	-	NC_000017.11:g.63355109G>T	NCI-TCGA
NCI-TCGA novel	p.Lys694Ter	stop gained	-	NC_000017.11:g.63355110A>T	NCI-TCGA
rs1477788468	p.Phe695Leu	missense variant	-	NC_000017.11:g.63355115C>A	gnomAD
COSM5747884	p.Pro696Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63355116C>T	NCI-TCGA Cosmic
COSM706515	p.Ser699Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63355126C>T	NCI-TCGA Cosmic
NCI-TCGA novel	p.Ser700Phe	missense variant	-	NC_000017.11:g.63355129C>T	NCI-TCGA
rs1164849683	p.Ser700Ala	missense variant	-	NC_000017.11:g.63355128T>G	TOPMed
rs1432072520	p.Arg703Trp	missense variant	-	NC_000017.11:g.63355137C>T	gnomAD
rs1335463551	p.Val704Glu	missense variant	-	NC_000017.11:g.63355141T>A	gnomAD
rs377236602	p.Met705Ile	missense variant	-	NC_000017.11:g.63355145G>T	ESP,TOPMed,gnomAD
rs759208072	p.Pro706Leu	missense variant	-	NC_000017.11:g.63355147C>T	ExAC,gnomAD
rs1163706857	p.Leu707Ile	missense variant	-	NC_000017.11:g.63355149C>A	TOPMed
rs752552645	p.Pro717Ala	missense variant	-	NC_000017.11:g.63355179C>G	ExAC,gnomAD
rs756100541	p.Leu718Val	missense variant	-	NC_000017.11:g.63355182C>G	ExAC,TOPMed,gnomAD
rs1285178130	p.Thr719Ser	missense variant	-	NC_000017.11:g.63355186C>G	TOPMed,gnomAD
rs753277402	p.Glu721Asp	missense variant	-	NC_000017.11:g.63355193G>C	ExAC,gnomAD
NCI-TCGA novel	p.Glu721Gln	missense variant	-	NC_000017.11:g.63355191G>C	NCI-TCGA
rs756772718	p.His722Arg	missense variant	-	NC_000017.11:g.63355195A>G	ExAC,TOPMed,gnomAD
rs1223831328	p.Ile723Val	missense variant	-	NC_000017.11:g.63355197A>G	TOPMed
rs1319965956	p.Ala726Val	missense variant	-	NC_000017.11:g.63355207C>T	TOPMed
rs1240724155	p.Asn728Lys	missense variant	-	NC_000017.11:g.63355214T>A	gnomAD
rs61743014	p.Asn728Ser	missense variant	-	NC_000017.11:g.63355213A>G	ExAC,TOPMed,gnomAD
rs370145697	p.Gly730Val	missense variant	-	NC_000017.11:g.63355219G>T	ESP,ExAC,TOPMed,gnomAD
rs933921170	p.Ser731Asn	missense variant	-	NC_000017.11:g.63355222G>A	TOPMed
rs1218472984	p.Thr735Lys	missense variant	-	NC_000017.11:g.63355234C>A	TOPMed
rs780527488	p.Leu736Val	missense variant	-	NC_000017.11:g.63355236C>G	ExAC,gnomAD
rs540526600	p.Trp738Ser	missense variant	-	NC_000017.11:g.63355243G>C	1000Genomes
rs1295844451	p.Asp740Val	missense variant	-	NC_000017.11:g.63355249A>T	TOPMed
rs747469714	p.Gln743Arg	missense variant	-	NC_000017.11:g.63355258A>G	ExAC,gnomAD
rs747469714	p.Gln743Leu	missense variant	-	NC_000017.11:g.63355258A>T	ExAC,gnomAD
rs1347559756	p.Met750Val	missense variant	-	NC_000017.11:g.63355278A>G	TOPMed
rs748185878	p.Met750Ile	missense variant	-	NC_000017.11:g.63355280G>T	ExAC,gnomAD
rs1324650049	p.Met750Thr	missense variant	-	NC_000017.11:g.63355279T>C	TOPMed
rs374748633	p.Phe751Leu	missense variant	-	NC_000017.11:g.63355283C>A	ESP,ExAC,TOPMed,gnomAD
rs374748633	p.Phe751Leu	missense variant	-	NC_000017.11:g.63355283C>G	ESP,ExAC,TOPMed,gnomAD
rs775421108	p.Arg755His	missense variant	-	NC_000017.11:g.63355294G>A	ExAC,TOPMed,gnomAD
rs767201600	p.Arg755Cys	missense variant	-	NC_000017.11:g.63355293C>T	ExAC,TOPMed,gnomAD
rs775421108	p.Arg755Leu	missense variant	-	NC_000017.11:g.63355294G>T	ExAC,TOPMed,gnomAD
rs760467526	p.Asp757Gly	missense variant	-	NC_000017.11:g.63355300A>G	ExAC,gnomAD
rs1427752221	p.Met758Ile	missense variant	-	NC_000017.11:g.63355304G>A	TOPMed
rs763961124	p.Thr759Ala	missense variant	-	NC_000017.11:g.63355305A>G	ExAC,gnomAD
rs1425650144	p.Thr759Ser	missense variant	-	NC_000017.11:g.63355306C>G	TOPMed
rs1282488329	p.Arg760Cys	missense variant	-	NC_000017.11:g.63355308C>T	TOPMed,gnomAD
rs1353225798	p.Arg760His	missense variant	-	NC_000017.11:g.63355309G>A	TOPMed,gnomAD
rs753804707	p.Phe762Ser	missense variant	-	NC_000017.11:g.63355315T>C	ExAC,gnomAD
rs1252383302	p.Val763Leu	missense variant	-	NC_000017.11:g.63355317G>T	TOPMed
rs1490007629	p.His764Tyr	missense variant	-	NC_000017.11:g.63355320C>T	TOPMed,gnomAD
rs1198699390	p.Pro765Thr	missense variant	-	NC_000017.11:g.63355323C>A	gnomAD
rs1234920001	p.Arg768Gln	missense variant	-	NC_000017.11:g.63355333G>A	TOPMed,gnomAD
COSM982536	p.Glu769Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63355337A>T	NCI-TCGA Cosmic
rs764852217	p.Leu771Phe	missense variant	-	NC_000017.11:g.63355341C>T	ExAC,gnomAD
rs762313677	p.Glu776Gly	missense variant	-	NC_000017.11:g.63355357A>G	TOPMed,gnomAD
rs367715498	p.Lys779Glu	missense variant	-	NC_000017.11:g.63355365A>G	ESP,ExAC,gnomAD
rs758139432	p.Thr780Ile	missense variant	-	NC_000017.11:g.63355369C>T	ExAC,TOPMed,gnomAD
rs1165266140	p.Thr780Pro	missense variant	-	NC_000017.11:g.63355368A>C	gnomAD
NCI-TCGA novel	p.Leu783Ile	missense variant	-	NC_000017.11:g.63355377C>A	NCI-TCGA
rs761798342	p.Thr791Met	missense variant	-	NC_000017.11:g.63379729C>T	ExAC,gnomAD
rs1194313825	p.Leu793Phe	missense variant	-	NC_000017.11:g.63379734C>T	TOPMed
rs1455681172	p.Ala794Ser	missense variant	-	NC_000017.11:g.63379737G>T	TOPMed
rs762386059	p.Phe795Val	missense variant	-	NC_000017.11:g.63379740T>G	ExAC,TOPMed,gnomAD
COSM982538	p.Ser798Pro	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63379749T>C	NCI-TCGA Cosmic
rs1461430188	p.Gln800Arg	missense variant	-	NC_000017.11:g.63379756A>G	gnomAD
rs766010730	p.Glu801Ala	missense variant	-	NC_000017.11:g.63379759A>C	ExAC,TOPMed,gnomAD
rs1240941420	p.Gly802Glu	missense variant	-	NC_000017.11:g.63379762G>A	gnomAD
rs1322854387	p.Arg806Gln	missense variant	-	NC_000017.11:g.63379774G>A	gnomAD
rs1194483156	p.Thr809Ala	missense variant	-	NC_000017.11:g.63379782A>G	TOPMed
COSM1385118	p.Gly813Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63379794G>T	NCI-TCGA Cosmic
COSM1385120	p.Gly813Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63379795G>T	NCI-TCGA Cosmic
rs755359691	p.His815Tyr	missense variant	-	NC_000017.11:g.63379800C>T	ExAC,gnomAD
rs1374531122	p.Ile816Asn	missense variant	-	NC_000017.11:g.63379804T>A	gnomAD
rs1429894558	p.Ala819Val	missense variant	-	NC_000017.11:g.63379813C>T	gnomAD
COSM982540	p.Phe822Cys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63379822T>G	NCI-TCGA Cosmic
rs1298570048	p.Val829Ile	missense variant	-	NC_000017.11:g.63388650G>A	gnomAD
rs1051009862	p.Gly830Cys	missense variant	-	NC_000017.11:g.63388653G>T	gnomAD
rs1051009862	p.Gly830Arg	missense variant	-	NC_000017.11:g.63388653G>C	gnomAD
rs368953403	p.Val831Ile	missense variant	-	NC_000017.11:g.63388656G>A	ESP,ExAC,TOPMed,gnomAD
rs1215672933	p.Ser833Thr	missense variant	-	NC_000017.11:g.63388662T>A	gnomAD
NCI-TCGA novel	p.Leu839Ile	missense variant	-	NC_000017.11:g.63388680C>A	NCI-TCGA
COSM1385122	p.Trp840Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63388684G>T	NCI-TCGA Cosmic
rs186712546	p.Ser842Phe	missense variant	-	NC_000017.11:g.63388690C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1197110814	p.Tyr843His	missense variant	-	NC_000017.11:g.63388692T>C	gnomAD
rs1266586082	p.Tyr843Cys	missense variant	-	NC_000017.11:g.63388693A>G	gnomAD
rs756447567	p.Ser844Thr	missense variant	-	NC_000017.11:g.63388696G>C	ExAC,gnomAD
rs376827865	p.Thr845Ala	missense variant	-	NC_000017.11:g.63388698A>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Glu846Asp	missense variant	-	NC_000017.11:g.63388703A>T	NCI-TCGA
rs754333999	p.Gly847Val	missense variant	-	NC_000017.11:g.63388705G>T	ExAC,TOPMed,gnomAD
rs754333999	p.Gly847Asp	missense variant	-	NC_000017.11:g.63388705G>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Leu848Ile	missense variant	-	NC_000017.11:g.63388707C>A	NCI-TCGA
rs1486953581	p.Ser849Phe	missense variant	-	NC_000017.11:g.63388711C>T	gnomAD
rs757337752	p.Ser849Pro	missense variant	-	NC_000017.11:g.63388710T>C	ExAC,gnomAD
rs1427114150	p.Met850Val	missense variant	-	NC_000017.11:g.63388713A>G	gnomAD
rs746084906	p.Ala851Thr	missense variant	-	NC_000017.11:g.63388716G>A	ExAC,gnomAD
rs1390622075	p.Ala851Val	missense variant	-	NC_000017.11:g.63388717C>T	gnomAD
NCI-TCGA novel	p.Leu852Val	missense variant	-	NC_000017.11:g.63388719C>G	NCI-TCGA
COSM4068519	p.Ala853Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63388723C>T	NCI-TCGA Cosmic
rs1368771075	p.Ala853Thr	missense variant	-	NC_000017.11:g.63388722G>A	TOPMed
rs1189333667	p.Ala853Glu	missense variant	-	NC_000017.11:g.63388723C>A	gnomAD
rs968360568	p.Arg856Gln	missense variant	-	NC_000017.11:g.63388732G>A	TOPMed,gnomAD
NCI-TCGA novel	p.Arg856Ter	stop gained	-	NC_000017.11:g.63388731C>T	NCI-TCGA
COSM982544	p.Leu858Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63388737C>A	NCI-TCGA Cosmic
rs1374227177	p.Tyr859Cys	missense variant	-	NC_000017.11:g.63388741A>G	gnomAD
NCI-TCGA novel	p.Tyr859LeuPheSerTerUnk	stop gained	-	NC_000017.11:g.63388740_63388741insTAAATTCAAGTTACTAAATTAC	NCI-TCGA
COSM277590	p.Pro861Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63388747C>A	NCI-TCGA Cosmic
rs1238900314	p.Ile863Thr	missense variant	-	NC_000017.11:g.63388753T>C	gnomAD
rs765735295	p.Arg867Ter	stop gained	-	NC_000017.11:g.63389314C>T	ExAC,gnomAD
rs1244021783	p.Arg867Gln	missense variant	-	NC_000017.11:g.63389315G>A	gnomAD
COSM4068521	p.Ile870Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63389323A>G	NCI-TCGA Cosmic
rs1180504890	p.Ala874Thr	missense variant	-	NC_000017.11:g.63389335G>A	gnomAD
rs750442027	p.Ile876Thr	missense variant	-	NC_000017.11:g.63389342T>C	ExAC,gnomAD
rs1251262612	p.Tyr878His	missense variant	-	NC_000017.11:g.63389347T>C	TOPMed
rs780205720	p.Arg879Gln	missense variant	-	NC_000017.11:g.63389351G>A	ExAC,TOPMed,gnomAD
rs758492232	p.Arg879Trp	missense variant	-	NC_000017.11:g.63389350C>T	ExAC,TOPMed,gnomAD
rs1308796802	p.Thr880Ile	missense variant	-	NC_000017.11:g.63389354C>T	gnomAD
rs755919425	p.Val882Leu	missense variant	-	NC_000017.11:g.63389359G>C	ExAC,gnomAD
rs915741295	p.Leu883Ser	missense variant	-	NC_000017.11:g.63389363T>C	TOPMed
rs777491096	p.Asn885Ser	missense variant	-	NC_000017.11:g.63389369A>G	ExAC,gnomAD
rs770927486	p.Pro887Ser	missense variant	-	NC_000017.11:g.63389374C>T	ExAC,gnomAD
rs774444805	p.Ile888Val	missense variant	-	NC_000017.11:g.63389377A>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Leu889Ile	missense variant	-	NC_000017.11:g.63389380C>A	NCI-TCGA
rs775177337	p.Cys890Ser	missense variant	-	NC_000017.11:g.63389384G>C	ExAC,gnomAD
rs760301830	p.Gly896Arg	missense variant	-	NC_000017.11:g.63389401G>C	ExAC,gnomAD
rs760301830	p.Gly896Ser	missense variant	-	NC_000017.11:g.63389401G>A	ExAC,gnomAD
rs776792236	p.Thr898Ile	missense variant	-	NC_000017.11:g.63389408C>T	ExAC,gnomAD
rs764514238	p.Thr898Pro	missense variant	-	NC_000017.11:g.63389407A>C	ExAC,gnomAD
rs377389715	p.Glu899Asp	missense variant	-	NC_000017.11:g.63389412A>T	ESP,ExAC,gnomAD
rs114552067	p.Met900Val	missense variant	-	NC_000017.11:g.63389413A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs568898605	p.Ala902Gly	missense variant	-	NC_000017.11:g.63389420C>G	1000Genomes
rs750956093	p.Leu903Pro	missense variant	-	NC_000017.11:g.63389423T>C	ExAC,gnomAD
rs1261702349	p.Leu905Arg	missense variant	-	NC_000017.11:g.63389429T>G	gnomAD
rs1045592537	p.Phe907Leu	missense variant	-	NC_000017.11:g.63389436C>G	TOPMed,gnomAD
rs766490830	p.Gly908Glu	missense variant	-	NC_000017.11:g.63389438G>A	ExAC,TOPMed,gnomAD
rs758438804	p.Gly908Arg	missense variant	-	NC_000017.11:g.63389437G>A	ExAC,TOPMed,gnomAD
rs751797493	p.Ala909Pro	missense variant	-	NC_000017.11:g.63389440G>C	ExAC,gnomAD
rs1370792562	p.Asn910Ser	missense variant	-	NC_000017.11:g.63389444A>G	TOPMed
rs781483616	p.Val911Met	missense variant	-	NC_000017.11:g.63389446G>A	ExAC,TOPMed,gnomAD
rs781483616	p.Val911Leu	missense variant	-	NC_000017.11:g.63389446G>T	ExAC,TOPMed,gnomAD
rs757141249	p.Ala913Thr	missense variant	-	NC_000017.11:g.63389452G>A	ExAC,gnomAD
rs778954803	p.Ala913Val	missense variant	-	NC_000017.11:g.63389453C>T	ExAC,gnomAD
rs757141249	p.Ala913Ser	missense variant	-	NC_000017.11:g.63389452G>T	ExAC,gnomAD
rs745840520	p.Ser914Ala	missense variant	-	NC_000017.11:g.63389455T>G	ExAC,gnomAD
rs771694104	p.Ser914Phe	missense variant	-	NC_000017.11:g.63389456C>T	ExAC,gnomAD
rs774928576	p.Glu916Lys	missense variant	-	NC_000017.11:g.63389461G>A	ExAC,gnomAD
rs746532546	p.Ser917Gly	missense variant	-	NC_000017.11:g.63389464A>G	ExAC,gnomAD
COSM982546	p.Gly918Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63389468G>A	NCI-TCGA Cosmic
rs1171699651	p.Gly923Val	missense variant	-	NC_000017.11:g.63389483G>T	TOPMed
rs1488255497	p.Tyr924Cys	missense variant	-	NC_000017.11:g.63389486A>G	gnomAD
rs1248959250	p.Ala927Thr	missense variant	-	NC_000017.11:g.63389494G>A	gnomAD
COSM6147664	p.Ala928Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63389497G>T	NCI-TCGA Cosmic
rs1408309416	p.Tyr930His	missense variant	-	NC_000017.11:g.63389503T>C	gnomAD
COSM3989214	p.Leu931Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63389506C>A	NCI-TCGA Cosmic
rs1417374551	p.Ser932Asn	missense variant	-	NC_000017.11:g.63389510G>A	TOPMed
rs377542271	p.Ser932Cys	missense variant	-	NC_000017.11:g.63389509A>T	ESP,ExAC,TOPMed,gnomAD
rs759677685	p.Ile933Thr	missense variant	-	NC_000017.11:g.63389513T>C	ExAC,TOPMed,gnomAD
rs1325516043	p.Val934Ala	missense variant	-	NC_000017.11:g.63389516T>C	gnomAD
rs1348029811	p.Val935Glu	missense variant	-	NC_000017.11:g.63389519T>A	gnomAD
COSM460271	p.Val935Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63389518G>A	NCI-TCGA Cosmic
COSM4068523	p.Leu936Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63389521C>G	NCI-TCGA Cosmic
rs1188866736	p.Lys939Glu	missense variant	-	NC_000017.11:g.63389530A>G	TOPMed
rs371161191	p.Arg941Gln	missense variant	-	NC_000017.11:g.63389537G>A	ESP,ExAC,TOPMed,gnomAD
rs1434453647	p.Arg941Trp	missense variant	-	NC_000017.11:g.63389536C>T	TOPMed,gnomAD
rs752996763	p.Ala942Thr	missense variant	-	NC_000017.11:g.63389539G>A	ExAC,gnomAD
rs1242507216	p.Lys943Glu	missense variant	-	NC_000017.11:g.63389542A>G	gnomAD
rs1396765568	p.His946Asn	missense variant	-	NC_000017.11:g.63395749C>A	TOPMed,gnomAD
rs1396765568	p.His946Tyr	missense variant	-	NC_000017.11:g.63395749C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Leu947Val	missense variant	-	NC_000017.11:g.63395752T>G	NCI-TCGA
rs767677178	p.Leu947Phe	missense variant	-	NC_000017.11:g.63395754G>T	ExAC,gnomAD
rs1287996037	p.Asp948Ala	missense variant	-	NC_000017.11:g.63395756A>C	TOPMed
rs906902782	p.Asp948Asn	missense variant	-	NC_000017.11:g.63395755G>A	TOPMed,gnomAD
rs778414080	p.Gly951Arg	missense variant	-	NC_000017.11:g.63395764G>A	TOPMed,gnomAD
rs778414080	p.Gly951Arg	missense variant	-	NC_000017.11:g.63395764G>C	TOPMed,gnomAD
rs761043795	p.Gln952His	missense variant	-	NC_000017.11:g.63395769G>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Gln952His	missense variant	-	NC_000017.11:g.63395769G>T	NCI-TCGA
rs1216292593	p.Gln952Arg	missense variant	-	NC_000017.11:g.63395768A>G	gnomAD
rs764415517	p.Cys953Tyr	missense variant	-	NC_000017.11:g.63395771G>A	ExAC,gnomAD
COSM437097	p.Cys953Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63395771G>T	NCI-TCGA Cosmic
rs1388353199	p.Val956Leu	missense variant	-	NC_000017.11:g.63395779G>C	TOPMed,gnomAD
rs1276056750	p.His957Arg	missense variant	-	NC_000017.11:g.63395783A>G	gnomAD
rs750182978	p.His957Tyr	missense variant	-	NC_000017.11:g.63395782C>T	ExAC,TOPMed,gnomAD
rs1195938676	p.Ala959Thr	missense variant	-	NC_000017.11:g.63395788G>A	TOPMed
NCI-TCGA novel	p.Leu960Val	missense variant	-	NC_000017.11:g.63395791C>G	NCI-TCGA
rs1265295257	p.Arg961Ter	stop gained	-	NC_000017.11:g.63395794C>T	gnomAD
rs374131489	p.Arg961Gln	missense variant	-	NC_000017.11:g.63395795G>A	ESP,ExAC,TOPMed,gnomAD
rs1191615667	p.Gly962Ser	missense variant	-	NC_000017.11:g.63395797G>A	gnomAD
rs1422928791	p.His963Arg	missense variant	-	NC_000017.11:g.63395801A>G	gnomAD
rs779813561	p.Val966Ile	missense variant	-	NC_000017.11:g.63395809G>A	ExAC,gnomAD
NCI-TCGA novel	p.Val966Phe	missense variant	-	NC_000017.11:g.63395809G>T	NCI-TCGA
rs751552018	p.Val967Ile	missense variant	-	NC_000017.11:g.63395812G>A	ExAC,gnomAD
rs754420162	p.Lys968Arg	missense variant	-	NC_000017.11:g.63395816A>G	ExAC,gnomAD
COSM5155349	p.Gln972Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63395828A>G	NCI-TCGA Cosmic
rs780807728	p.Thr976Met	missense variant	-	NC_000017.11:g.63395840C>T	ExAC,TOPMed,gnomAD
rs1027886300	p.Met977Ile	missense variant	-	NC_000017.11:g.63395844G>A	TOPMed,gnomAD
rs755699792	p.Gly979Ser	missense variant	-	NC_000017.11:g.63395848G>A	ExAC,TOPMed,gnomAD
rs367676849	p.Gln980Arg	missense variant	-	NC_000017.11:g.63395852A>G	ESP,ExAC,gnomAD
rs113065000	p.Gln980Ter	stop gained	-	NC_000017.11:g.63395851C>T	1000Genomes
COSM4068525	p.Gly983Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63395860G>A	NCI-TCGA Cosmic
rs749608007	p.Val984Ile	missense variant	-	NC_000017.11:g.63395863G>A	ExAC,TOPMed,gnomAD
rs771360193	p.Val984Glu	missense variant	-	NC_000017.11:g.63395864T>A	ExAC,TOPMed,gnomAD
rs749608007	p.Val984Leu	missense variant	-	NC_000017.11:g.63395863G>C	ExAC,TOPMed,gnomAD
rs1217104853	p.Lys986Arg	missense variant	-	NC_000017.11:g.63395870A>G	gnomAD
rs774691299	p.Ser988Gly	missense variant	-	NC_000017.11:g.63395875A>G	ExAC,gnomAD
rs746436568	p.Ala990Thr	missense variant	-	NC_000017.11:g.63395881G>A	ExAC,gnomAD
NCI-TCGA novel	p.Gln993His	missense variant	-	NC_000017.11:g.63395892G>T	NCI-TCGA
rs925525321	p.Ala997Val	missense variant	-	NC_000017.11:g.63395903C>T	gnomAD
rs1441132640	p.Ala999Gly	missense variant	-	NC_000017.11:g.63395909C>G	TOPMed,gnomAD
rs557700809	p.Thr1004Ile	missense variant	-	NC_000017.11:g.63395924C>T	1000Genomes
rs1208404617	p.Ile1006Val	missense variant	-	NC_000017.11:g.63398821A>G	TOPMed,gnomAD
rs1319792567	p.Val1007Ile	missense variant	-	NC_000017.11:g.63398824G>A	TOPMed
rs1160961847	p.Ser1008Cys	missense variant	-	NC_000017.11:g.63398828C>G	TOPMed,gnomAD
rs1160961847	p.Ser1008Tyr	missense variant	-	NC_000017.11:g.63398828C>A	TOPMed,gnomAD
NCI-TCGA novel	p.Asp1012His	missense variant	-	NC_000017.11:g.63398839G>C	NCI-TCGA
rs913769112	p.Lys1016Glu	missense variant	-	NC_000017.11:g.63398851A>G	TOPMed,gnomAD
rs1333009579	p.Asp1017Asn	missense variant	-	NC_000017.11:g.63398854G>A	gnomAD
NCI-TCGA novel	p.Glu1018Lys	missense variant	-	NC_000017.11:g.63398857G>A	NCI-TCGA
rs1374165658	p.Glu1019Ala	missense variant	-	NC_000017.11:g.63398861A>C	gnomAD
COSM4919588	p.Arg1023Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63398872C>T	NCI-TCGA Cosmic
rs1423425524	p.Ser1028Cys	missense variant	-	NC_000017.11:g.63398887A>T	TOPMed
rs776968832	p.Ser1031Thr	missense variant	-	NC_000017.11:g.63398897G>C	ExAC,gnomAD
rs776968832	p.Ser1031Asn	missense variant	-	NC_000017.11:g.63398897G>A	ExAC,gnomAD
rs762149740	p.Leu1032Val	missense variant	-	NC_000017.11:g.63398899C>G	ExAC,gnomAD
rs762149740	p.Leu1032Phe	missense variant	-	NC_000017.11:g.63398899C>T	ExAC,gnomAD
COSM4825823	p.Glu1035Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63398908G>C	NCI-TCGA Cosmic
rs1177008187	p.Thr1036Ile	missense variant	-	NC_000017.11:g.63398912C>T	gnomAD
rs374605275	p.Ala1042Val	missense variant	-	NC_000017.11:g.63405137C>T	ESP,ExAC,gnomAD
rs200323393	p.Gly1043Arg	missense variant	-	NC_000017.11:g.63405139G>A	ESP,ExAC,TOPMed,gnomAD
rs200323393	p.Gly1043Ter	stop gained	-	NC_000017.11:g.63405139G>T	ESP,ExAC,TOPMed,gnomAD
rs190187657	p.Gly1043Ala	missense variant	-	NC_000017.11:g.63405140G>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys1046GlnPheSerTerUnkUnk	frameshift	-	NC_000017.11:g.63405142_63405143insG	NCI-TCGA
NCI-TCGA novel	p.Cys1050Tyr	missense variant	-	NC_000017.11:g.63405161G>A	NCI-TCGA
rs1369067776	p.Arg1051Cys	missense variant	-	NC_000017.11:g.63405163C>T	TOPMed
rs753330160	p.Arg1051His	missense variant	-	NC_000017.11:g.63405164G>A	ExAC,TOPMed,gnomAD
rs761251537	p.Ala1058Val	missense variant	-	NC_000017.11:g.63405185C>T	ExAC,gnomAD
rs1399021803	p.Ala1059Thr	missense variant	-	NC_000017.11:g.63405187G>A	TOPMed
rs1446885616	p.Ala1061Thr	missense variant	-	NC_000017.11:g.63405193G>A	gnomAD
rs1221689321	p.Pro1063Thr	missense variant	-	NC_000017.11:g.63405199C>A	gnomAD
rs1025704226	p.Asn1064Asp	missense variant	-	NC_000017.11:g.63405202A>G	TOPMed
rs545352608	p.Arg1065Cys	missense variant	-	NC_000017.11:g.63405205C>T	1000Genomes,ExAC,gnomAD
rs750081650	p.Arg1065His	missense variant	-	NC_000017.11:g.63405206G>A	ExAC,TOPMed,gnomAD
rs758810518	p.Arg1066Leu	missense variant	-	NC_000017.11:g.63405209G>T	ExAC,TOPMed,gnomAD
rs758810518	p.Arg1066Gln	missense variant	-	NC_000017.11:g.63405209G>A	ExAC,TOPMed,gnomAD
COSM1324918	p.Arg1066Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63405208C>T	NCI-TCGA Cosmic
rs1156572294	p.Leu1071Val	missense variant	-	NC_000017.11:g.63405223C>G	gnomAD
rs769797251	p.Thr1074Ser	missense variant	-	NC_000017.11:g.63405232A>T	ExAC
rs771843402	p.Arg1076Leu	missense variant	-	NC_000017.11:g.63405239G>T	ExAC,TOPMed,gnomAD
rs771843402	p.Arg1076His	missense variant	-	NC_000017.11:g.63405239G>A	ExAC,TOPMed,gnomAD
rs368122235	p.Arg1076Cys	missense variant	-	NC_000017.11:g.63405238C>T	ESP,ExAC,TOPMed,gnomAD
rs368122235	p.Arg1076Gly	missense variant	-	NC_000017.11:g.63405238C>G	ESP,ExAC,TOPMed,gnomAD
rs1377882035	p.His1079Tyr	missense variant	-	NC_000017.11:g.63405247C>T	gnomAD
rs756199846	p.Leu1085Val	missense variant	-	NC_000017.11:g.63406163C>G	ExAC,gnomAD
COSM982548	p.Leu1085Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63406163C>A	NCI-TCGA Cosmic
NCI-TCGA novel	p.Leu1086TyrPheSerTerUnkUnk	frameshift	-	NC_000017.11:g.63406164T>-	NCI-TCGA
rs1263632797	p.Thr1088Ile	missense variant	-	NC_000017.11:g.63406173C>T	TOPMed
rs1232176889	p.His1089Arg	missense variant	-	NC_000017.11:g.63406176A>G	TOPMed,gnomAD
rs1319565162	p.Gly1090Glu	missense variant	-	NC_000017.11:g.63406179G>A	gnomAD
NCI-TCGA novel	p.Ala1091Pro	missense variant	-	NC_000017.11:g.63406181G>C	NCI-TCGA
rs1196447873	p.Met1095Thr	missense variant	-	NC_000017.11:g.63406194T>C	gnomAD
rs1271839894	p.Ala1096Gly	missense variant	-	NC_000017.11:g.63406197C>G	gnomAD
NCI-TCGA novel	p.Ala1096Thr	missense variant	-	NC_000017.11:g.63406196G>A	NCI-TCGA
rs1211931490	p.Asp1097Glu	missense variant	-	NC_000017.11:g.63406201C>A	gnomAD
rs757405529	p.Asp1097Gly	missense variant	-	NC_000017.11:g.63406200A>G	ExAC,gnomAD
rs779128919	p.Gln1099His	missense variant	-	NC_000017.11:g.63406207G>T	ExAC,gnomAD
rs768478015	p.Arg1101Cys	missense variant	-	NC_000017.11:g.63406211C>T	ExAC,TOPMed,gnomAD
rs1187322521	p.Thr1102Ile	missense variant	-	NC_000017.11:g.63406215C>T	gnomAD
rs1364742226	p.Pro1103Ala	missense variant	-	NC_000017.11:g.63406217C>G	TOPMed
NCI-TCGA novel	p.Leu1104Arg	missense variant	-	NC_000017.11:g.63406221T>G	NCI-TCGA
rs1326784090	p.Met1105Ile	missense variant	-	NC_000017.11:g.63406225G>C	TOPMed
rs776606839	p.Met1105Thr	missense variant	-	NC_000017.11:g.63406224T>C	ExAC,gnomAD
rs976637040	p.Glu1110Lys	missense variant	-	NC_000017.11:g.63406238G>A	TOPMed,gnomAD
rs1396013752	p.His1112Gln	missense variant	-	NC_000017.11:g.63406246T>A	gnomAD
rs769339759	p.Leu1113Val	missense variant	-	NC_000017.11:g.63406247C>G	ExAC,gnomAD
rs1356647932	p.Gly1114Arg	missense variant	-	NC_000017.11:g.63406250G>A	gnomAD
rs762562307	p.Val1116Leu	missense variant	-	NC_000017.11:g.63406256G>C	ExAC,gnomAD
rs762562307	p.Val1116Met	missense variant	-	NC_000017.11:g.63406256G>A	ExAC,gnomAD
NCI-TCGA novel	p.Asp1117Gly	missense variant	-	NC_000017.11:g.63406260A>G	NCI-TCGA
rs774182442	p.Leu1119Val	missense variant	-	NC_000017.11:g.63406265C>G	ExAC,gnomAD
COSM1385124	p.Leu1120Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63406268C>T	NCI-TCGA Cosmic
rs1286771997	p.Ala1121Val	missense variant	-	NC_000017.11:g.63406272C>T	TOPMed,gnomAD
rs1316954824	p.Ala1124Ser	missense variant	-	NC_000017.11:g.63411513G>T	gnomAD
rs769557502	p.Ser1125Phe	missense variant	-	NC_000017.11:g.63411517C>T	ExAC,gnomAD
rs1173226314	p.Ser1125Thr	missense variant	-	NC_000017.11:g.63411516T>A	TOPMed
rs773301798	p.Ile1126Met	missense variant	-	NC_000017.11:g.63411521T>G	ExAC,gnomAD
rs201991449	p.Met1129Thr	missense variant	-	NC_000017.11:g.63411529T>C	ESP,ExAC,TOPMed,gnomAD
rs534793801	p.Ala1136Pro	missense variant	-	NC_000017.11:g.63411549G>C	1000Genomes,ExAC,gnomAD
rs1437686978	p.Leu1142Ser	missense variant	-	NC_000017.11:g.63411568T>C	TOPMed
rs1203482098	p.His1145Arg	missense variant	-	NC_000017.11:g.63411577A>G	gnomAD
rs77573295	p.Ser1147Pro	missense variant	-	NC_000017.11:g.63411582T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1230917443	p.Val1148Ile	missense variant	-	NC_000017.11:g.63411585G>A	gnomAD
rs377115331	p.Arg1150His	missense variant	-	NC_000017.11:g.63411592G>A	ESP,ExAC,TOPMed,gnomAD
rs775650558	p.Arg1150Cys	missense variant	-	NC_000017.11:g.63411591C>T	ExAC,gnomAD
rs764467626	p.Asp1154Tyr	missense variant	-	NC_000017.11:g.63411603G>T	ExAC,gnomAD
rs531389009	p.Asp1154Gly	missense variant	-	NC_000017.11:g.63411604A>G	ExAC,TOPMed,gnomAD
rs1159591545	p.Asn1155Ile	missense variant	-	NC_000017.11:g.63411607A>T	gnomAD
rs1253920589	p.Asn1155Asp	missense variant	-	NC_000017.11:g.63411606A>G	TOPMed
RCV000678329	p.Gly1156Val	missense variant	-	NC_000017.11:g.63411610G>T	ClinVar
rs1354224699	p.Gly1156Arg	missense variant	-	NC_000017.11:g.63411609G>A	TOPMed
rs761859549	p.Ala1157Pro	missense variant	-	NC_000017.11:g.63411612G>C	ExAC,gnomAD
rs750635698	p.Ala1158Thr	missense variant	-	NC_000017.11:g.63411615G>A	ExAC,TOPMed,gnomAD
rs758478943	p.Ala1158Asp	missense variant	-	NC_000017.11:g.63411616C>A	ExAC,TOPMed,gnomAD
rs1387995348	p.Thr1159Lys	missense variant	-	NC_000017.11:g.63411619C>A	gnomAD
rs780335147	p.Asp1160Glu	missense variant	-	NC_000017.11:g.63411623C>A	ExAC,gnomAD
rs1323538032	p.Asp1160His	missense variant	-	NC_000017.11:g.63411621G>C	gnomAD
rs895904203	p.His1161Asp	missense variant	-	NC_000017.11:g.63411624C>G	TOPMed
rs777825224	p.Arg1167Pro	missense variant	-	NC_000017.11:g.63411643G>C	ExAC,TOPMed,gnomAD
rs755972267	p.Arg1167Cys	missense variant	-	NC_000017.11:g.63411642C>T	ExAC,TOPMed
rs777825224	p.Arg1167His	missense variant	-	NC_000017.11:g.63411643G>A	ExAC,TOPMed,gnomAD
rs1400120288	p.Pro1169Ala	missense variant	-	NC_000017.11:g.63411648C>G	TOPMed
rs1312558593	p.Ala1173Thr	missense variant	-	NC_000017.11:g.63411660G>A	TOPMed
rs778633795	p.Ala1174Ser	missense variant	-	NC_000017.11:g.63411663G>T	ExAC
rs745388587	p.Ala1174Gly	missense variant	-	NC_000017.11:g.63411664C>G	ExAC,gnomAD
rs771568324	p.Tyr1176Cys	missense variant	-	NC_000017.11:g.63411670A>G	ExAC,TOPMed,gnomAD
rs775232466	p.Gly1177Ser	missense variant	-	NC_000017.11:g.63411672G>A	ExAC,gnomAD
rs1179665050	p.Asp1178Asn	missense variant	-	NC_000017.11:g.63411675G>A	gnomAD
NCI-TCGA novel	p.Asp1178Tyr	missense variant	-	NC_000017.11:g.63411675G>T	NCI-TCGA
rs1046870172	p.Asp1178Val	missense variant	-	NC_000017.11:g.63411676A>T	TOPMed
NCI-TCGA novel	p.Glu1180Asp	missense variant	-	NC_000017.11:g.63411683G>T	NCI-TCGA
NCI-TCGA novel	p.Glu1180Lys	missense variant	-	NC_000017.11:g.63411681G>A	NCI-TCGA
rs1005400347	p.Val1181Leu	missense variant	-	NC_000017.11:g.63411684G>C	TOPMed,gnomAD
COSM437099	p.Val1182Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63411998G>A	NCI-TCGA Cosmic
rs1270765216	p.Val1186Ile	missense variant	-	NC_000017.11:g.63412010G>A	gnomAD
rs766532566	p.Val1186Ala	missense variant	-	NC_000017.11:g.63412011T>C	ExAC,gnomAD
rs774426806	p.Asp1187Gly	missense variant	-	NC_000017.11:g.63412014A>G	ExAC,gnomAD
rs759873225	p.Ala1190Val	missense variant	-	NC_000017.11:g.63412023C>T	ExAC,gnomAD
rs767857326	p.Met1191Val	missense variant	-	NC_000017.11:g.63412025A>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Met1191Ile	missense variant	-	NC_000017.11:g.63412027G>A	NCI-TCGA
rs201127113	p.Ile1192Met	missense variant	-	NC_000017.11:g.63412030C>G	ESP,ExAC,TOPMed,gnomAD
rs1486855966	p.Glu1193Lys	missense variant	-	NC_000017.11:g.63412031G>A	gnomAD
rs1204942102	p.His1194Leu	missense variant	-	NC_000017.11:g.63412035A>T	gnomAD
rs1449638267	p.Val1195Ala	missense variant	-	NC_000017.11:g.63412038T>C	TOPMed
rs750422428	p.Val1195Ile	missense variant	-	NC_000017.11:g.63412037G>A	ExAC,TOPMed,gnomAD
rs756223486	p.Tyr1197Cys	missense variant	-	NC_000017.11:g.63412044A>G	ExAC,TOPMed,gnomAD
rs1187720722	p.Ser1198Thr	missense variant	-	NC_000017.11:g.63412047G>C	TOPMed,gnomAD
rs1416971626	p.Ser1198Arg	missense variant	-	NC_000017.11:g.63412048T>G	gnomAD
COSM6147660	p.Gly1199Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63412050G>A	NCI-TCGA Cosmic
rs901125104	p.Arg1201Cys	missense variant	-	NC_000017.11:g.63412055C>T	-
rs201488189	p.Arg1201His	missense variant	-	NC_000017.11:g.63412056G>A	ESP,ExAC,TOPMed,gnomAD
COSM5073509	p.Pro1202Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63412058C>T	NCI-TCGA Cosmic
rs746505172	p.Asp1204Glu	missense variant	-	NC_000017.11:g.63412066T>G	ExAC,TOPMed,gnomAD
rs1052193629	p.Arg1205Gly	missense variant	-	NC_000017.11:g.63412067A>G	gnomAD
rs780840821	p.Arg1210Gln	missense variant	-	NC_000017.11:g.63412083G>A	ExAC,TOPMed,gnomAD
rs1172991031	p.Arg1210Trp	missense variant	-	NC_000017.11:g.63412082C>T	gnomAD
rs770181673	p.Thr1212Asn	missense variant	-	NC_000017.11:g.63412089C>A	ExAC
rs1290658354	p.Thr1212Ala	missense variant	-	NC_000017.11:g.63412088A>G	gnomAD
rs1452415768	p.Ser1213Thr	missense variant	-	NC_000017.11:g.63412091T>A	TOPMed
rs749866687	p.Val1216Leu	missense variant	-	NC_000017.11:g.63412100G>C	ExAC,gnomAD
rs1010959592	p.Thr1217Ser	missense variant	-	NC_000017.11:g.63412104C>G	TOPMed,gnomAD
rs1010959592	p.Thr1217Ile	missense variant	-	NC_000017.11:g.63412104C>T	TOPMed,gnomAD
rs1350562153	p.Leu1218Phe	missense variant	-	NC_000017.11:g.63412106C>T	gnomAD
rs1350562153	p.Leu1218Ile	missense variant	-	NC_000017.11:g.63412106C>A	gnomAD
NCI-TCGA novel	p.Lys1220Asn	missense variant	-	NC_000017.11:g.63412114G>C	NCI-TCGA
rs184619475	p.Gly1222Glu	missense variant	-	NC_000017.11:g.63412119G>A	1000Genomes
rs770916010	p.Lys1224Arg	missense variant	-	NC_000017.11:g.63412125A>G	ExAC,TOPMed,gnomAD
rs1473050584	p.Ala1228Thr	missense variant	-	NC_000017.11:g.63413548G>A	gnomAD
rs1474261850	p.Ala1231Thr	missense variant	-	NC_000017.11:g.63413557G>A	gnomAD
rs1420460126	p.Thr1234Ile	missense variant	-	NC_000017.11:g.63413567C>T	gnomAD
rs761043580	p.Asp1238Asn	missense variant	-	NC_000017.11:g.63413578G>A	ExAC,TOPMed,gnomAD
rs768763926	p.Ile1239Thr	missense variant	-	NC_000017.11:g.63413582T>C	ExAC,gnomAD
rs1354480250	p.Ile1239Val	missense variant	-	NC_000017.11:g.63413581A>G	TOPMed,gnomAD
rs1353072898	p.Met1240Leu	missense variant	-	NC_000017.11:g.63413584A>C	gnomAD
rs1232115382	p.Met1240Thr	missense variant	-	NC_000017.11:g.63413585T>C	gnomAD
rs773002015	p.Ile1241Val	missense variant	-	NC_000017.11:g.63413587A>G	ExAC,gnomAD
rs1340975941	p.Ile1241Thr	missense variant	-	NC_000017.11:g.63413588T>C	gnomAD
rs1212598093	p.Ile1242Phe	missense variant	-	NC_000017.11:g.63413590A>T	gnomAD
rs766295871	p.Ser1245Asn	missense variant	-	NC_000017.11:g.63413600G>A	ExAC,gnomAD
rs751534960	p.Lys1246Gln	missense variant	-	NC_000017.11:g.63413602A>C	ExAC,gnomAD
rs759022503	p.Met1248Val	missense variant	-	NC_000017.11:g.63413608A>G	ExAC,gnomAD
rs776021083	p.Met1248Ile	missense variant	-	NC_000017.11:g.63413610G>A	ExAC,gnomAD
rs1242940560	p.Asp1252Asn	missense variant	-	NC_000017.11:g.63413620G>A	gnomAD
rs752345323	p.Asp1252Val	missense variant	-	NC_000017.11:g.63413621A>T	ExAC,gnomAD
rs939147095	p.Gly1258Asp	missense variant	-	NC_000017.11:g.63415532G>A	TOPMed,gnomAD
rs752149176	p.Val1260Ile	missense variant	-	NC_000017.11:g.63415537G>A	ExAC,gnomAD
rs760125888	p.Lys1261Arg	missense variant	-	NC_000017.11:g.63415541A>G	ExAC,gnomAD
rs1352984108	p.Lys1261Asn	missense variant	-	NC_000017.11:g.63415542G>T	gnomAD
COSM6081827	p.Glu1262Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63415543G>A	NCI-TCGA Cosmic
rs753474791	p.Gln1265Glu	missense variant	-	NC_000017.11:g.63415552C>G	ExAC,gnomAD
rs757622270	p.Arg1266Cys	missense variant	-	NC_000017.11:g.63415555C>T	ExAC,TOPMed,gnomAD
rs897727078	p.Arg1266His	missense variant	-	NC_000017.11:g.63415556G>A	TOPMed,gnomAD
NCI-TCGA novel	p.Tyr1267Cys	missense variant	-	NC_000017.11:g.63415559A>G	NCI-TCGA
rs1251593257	p.Gln1268Arg	missense variant	-	NC_000017.11:g.63415562A>G	gnomAD
rs370300150	p.Tyr1269Cys	missense variant	-	NC_000017.11:g.63415565A>G	ESP,ExAC,gnomAD
COSM706511	p.Tyr1269Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63415566C>A	NCI-TCGA Cosmic
rs1366031139	p.Ala1270Thr	missense variant	-	NC_000017.11:g.63415567G>A	gnomAD
rs780728787	p.Phe1274Leu	missense variant	-	NC_000017.11:g.63415579T>C	ExAC,gnomAD
VAR_079853	p.Gly1280Val	Missense	-	-	UniProt
rs540743422	p.Glu1281Asp	missense variant	-	NC_000017.11:g.63415602G>T	1000Genomes,ExAC,gnomAD
rs768655244	p.Asp1282Asn	missense variant	-	NC_000017.11:g.63415603G>A	ExAC,gnomAD
rs1393534829	p.Thr1285Ala	missense variant	-	NC_000017.11:g.63415612A>G	gnomAD
rs370892096	p.Phe1286Tyr	missense variant	-	NC_000017.11:g.63415616T>A	TOPMed,gnomAD
rs370892096	p.Phe1286Ser	missense variant	-	NC_000017.11:g.63415616T>C	TOPMed,gnomAD
rs372803024	p.Arg1287Trp	missense variant	-	NC_000017.11:g.63415618C>T	ESP,ExAC,TOPMed,gnomAD
rs748373533	p.Arg1287Gln	missense variant	-	NC_000017.11:g.63415619G>A	ExAC,TOPMed,gnomAD
rs1287729135	p.Lys1290Asn	missense variant	-	NC_000017.11:g.63415629G>T	gnomAD
rs981882459	p.Val1291Met	missense variant	-	NC_000017.11:g.63415630G>A	TOPMed
COSM263962	p.Ser1292Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63415634C>A	NCI-TCGA Cosmic
COSM3520606	p.Leu1295Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63415642C>T	NCI-TCGA Cosmic
rs376982885	p.Asn1296Ser	missense variant	-	NC_000017.11:g.63415646A>G	ESP,ExAC,TOPMed,gnomAD
rs1392008390	p.Asn1296Asp	missense variant	-	NC_000017.11:g.63415645A>G	TOPMed
rs745679564	p.Ser1298Phe	missense variant	-	NC_000017.11:g.63415652C>T	ExAC,TOPMed,gnomAD
rs745679564	p.Ser1298Cys	missense variant	-	NC_000017.11:g.63415652C>G	ExAC,TOPMed,gnomAD
rs771952102	p.Arg1299Gln	missense variant	-	NC_000017.11:g.63415655G>A	ExAC,TOPMed,gnomAD
rs1436521684	p.Arg1301Cys	missense variant	-	NC_000017.11:g.63415660C>T	TOPMed,gnomAD
rs1180475181	p.Arg1301His	missense variant	-	NC_000017.11:g.63415661G>A	TOPMed,gnomAD
rs1202858275	p.Arg1302Met	missense variant	-	NC_000017.11:g.63415664G>T	gnomAD
rs1285698846	p.Arg1302Ser	missense variant	-	NC_000017.11:g.63415665G>T	gnomAD
rs760202448	p.Met1304Val	missense variant	-	NC_000017.11:g.63415669A>G	ExAC,gnomAD
NCI-TCGA novel	p.Asn1305Lys	missense variant	-	NC_000017.11:g.63415674C>G	NCI-TCGA
rs1371182996	p.Gly1308Glu	missense variant	-	NC_000017.11:g.63418314G>A	gnomAD
rs200373356	p.Met1309Val	missense variant	-	NC_000017.11:g.63418316A>G	ExAC,TOPMed,gnomAD
rs1174223914	p.Ala1310Val	missense variant	-	NC_000017.11:g.63418320C>T	gnomAD
rs1416729665	p.Glu1311Lys	missense variant	-	NC_000017.11:g.63418322G>A	gnomAD
rs746979235	p.Phe1313Cys	missense variant	-	NC_000017.11:g.63418329T>G	ExAC,gnomAD
rs1383056376	p.Ala1317Ser	missense variant	-	NC_000017.11:g.63418340G>T	gnomAD
rs1297980683	p.Leu1320Pro	missense variant	-	NC_000017.11:g.63418350T>C	gnomAD
rs768640765	p.Lys1321Gln	missense variant	-	NC_000017.11:g.63418352A>C	ExAC,gnomAD
rs1005228380	p.Pro1322Leu	missense variant	-	NC_000017.11:g.63418356C>T	TOPMed
rs1228086655	p.Pro1322Ser	missense variant	-	NC_000017.11:g.63418355C>T	gnomAD
rs372098365	p.Tyr1325Cys	missense variant	-	NC_000017.11:g.63418365A>G	ESP,ExAC,TOPMed,gnomAD
rs534658690	p.Tyr1325His	missense variant	-	NC_000017.11:g.63418364T>C	1000Genomes,ExAC,gnomAD
rs763384774	p.Glu1326Asp	missense variant	-	NC_000017.11:g.63418369A>C	ExAC,gnomAD
rs1187944657	p.Tyr1329Cys	missense variant	-	NC_000017.11:g.63418377A>G	gnomAD
COSM982554	p.Ala1330Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63418380C>T	NCI-TCGA Cosmic
rs1293608116	p.Arg1331Ser	missense variant	-	NC_000017.11:g.63418384A>C	TOPMed,gnomAD
rs1193978319	p.Arg1333Lys	missense variant	-	NC_000017.11:g.63418389G>A	gnomAD
rs752099639	p.Arg1336His	missense variant	-	NC_000017.11:g.63418398G>A	ExAC,TOPMed,gnomAD
rs1396830120	p.Arg1336Cys	missense variant	-	NC_000017.11:g.63418397C>T	gnomAD
rs1172936886	p.Ser1337Asn	missense variant	-	NC_000017.11:g.63418401G>A	gnomAD
COSM86501	p.Arg1339Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63418407G>A	NCI-TCGA Cosmic
rs1293488634	p.Gln1340Ter	stop gained	-	NC_000017.11:g.63420000C>T	gnomAD
rs141384353	p.Ala1342Ser	missense variant	-	NC_000017.11:g.63420006G>T	1000Genomes,ExAC,TOPMed,gnomAD
rs141384353	p.Ala1342Thr	missense variant	-	NC_000017.11:g.63420006G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs542885777	p.Ala1344Thr	missense variant	-	NC_000017.11:g.63420012G>A	1000Genomes,TOPMed,gnomAD
rs932382460	p.Leu1345Phe	missense variant	-	NC_000017.11:g.63420017A>C	gnomAD
rs375384579	p.Glu1346Lys	missense variant	-	NC_000017.11:g.63420018G>A	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Leu1348Met	missense variant	-	NC_000017.11:g.63420024C>A	NCI-TCGA
rs1467002389	p.Glu1350Lys	missense variant	-	NC_000017.11:g.63420030G>A	gnomAD
rs559873644	p.Ala1351Thr	missense variant	-	NC_000017.11:g.63420033G>A	1000Genomes,ExAC,gnomAD
rs747580283	p.Arg1359Cys	missense variant	-	NC_000017.11:g.63420057C>T	ExAC,TOPMed,gnomAD
rs369106640	p.Leu1365Val	missense variant	-	NC_000017.11:g.63420075C>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1472290831	p.Arg1367Lys	missense variant	-	NC_000017.11:g.63420082G>A	gnomAD
rs1171779676	p.Val1368Leu	missense variant	-	NC_000017.11:g.63420084G>C	TOPMed,gnomAD
rs372679973	p.Glu1369Lys	missense variant	-	NC_000017.11:g.63420087G>A	ESP,ExAC,TOPMed,gnomAD
rs1420237316	p.Glu1370Lys	missense variant	-	NC_000017.11:g.63420090G>A	gnomAD
rs1403973386	p.Glu1371Val	missense variant	-	NC_000017.11:g.63420094A>T	gnomAD
rs770714662	p.Arg1373Lys	missense variant	-	NC_000017.11:g.63420100G>A	ExAC,gnomAD
rs1307280466	p.Met1375Ile	missense variant	-	NC_000017.11:g.63420107G>A	TOPMed
rs995565435	p.Gln1376Glu	missense variant	-	NC_000017.11:g.63420108C>G	TOPMed,gnomAD
rs774523963	p.Pro1378Arg	missense variant	-	NC_000017.11:g.63420115C>G	ExAC,gnomAD
rs774523963	p.Pro1378Leu	missense variant	-	NC_000017.11:g.63420115C>T	ExAC,gnomAD
rs1028422577	p.Gln1379Pro	missense variant	-	NC_000017.11:g.63420118A>C	TOPMed,gnomAD
rs1028422577	p.Gln1379Arg	missense variant	-	NC_000017.11:g.63420118A>G	TOPMed,gnomAD
rs1227535893	p.Gln1379His	missense variant	-	NC_000017.11:g.63420119G>T	gnomAD
rs1273529569	p.Gln1380Ter	stop gained	-	NC_000017.11:g.63420120C>T	gnomAD
rs1309026358	p.Pro1381Thr	missense variant	-	NC_000017.11:g.63420123C>A	TOPMed,gnomAD
rs1309026358	p.Pro1381Ala	missense variant	-	NC_000017.11:g.63420123C>G	TOPMed,gnomAD
rs1202412676	p.Pro1382Leu	missense variant	-	NC_000017.11:g.63420127C>T	gnomAD
rs564995228	p.Pro1383Leu	missense variant	-	NC_000017.11:g.63420130C>T	1000Genomes,TOPMed,gnomAD
rs564995228	p.Pro1383Gln	missense variant	-	NC_000017.11:g.63420130C>A	1000Genomes,TOPMed,gnomAD
rs1188684495	p.Pro1385Leu	missense variant	-	NC_000017.11:g.63420136C>T	gnomAD
rs1471896917	p.Pro1387Ser	missense variant	-	NC_000017.11:g.63420141C>T	gnomAD
rs753291375	p.Gln1388Leu	missense variant	-	NC_000017.11:g.63420145A>T	ExAC,gnomAD
rs753291375	p.Gln1388Arg	missense variant	-	NC_000017.11:g.63420145A>G	ExAC,gnomAD
rs1420746049	p.Gln1389His	missense variant	-	NC_000017.11:g.63420149G>T	gnomAD
rs1411982789	p.Gln1390Leu	missense variant	-	NC_000017.11:g.63420151A>T	gnomAD
rs760725231	p.Leu1391Phe	missense variant	-	NC_000017.11:g.63420155G>C	ExAC,TOPMed,gnomAD
rs754057352	p.Pro1392Arg	missense variant	-	NC_000017.11:g.63420157C>G	ExAC,TOPMed,gnomAD
rs764219146	p.Pro1392Ser	missense variant	-	NC_000017.11:g.63420156C>T	ExAC,TOPMed,gnomAD
rs764219146	p.Pro1392Thr	missense variant	-	NC_000017.11:g.63420156C>A	ExAC,TOPMed,gnomAD
rs754057352	p.Pro1392Leu	missense variant	-	NC_000017.11:g.63420157C>T	ExAC,TOPMed,gnomAD
rs1446908607	p.Glu1394Ala	missense variant	-	NC_000017.11:g.63420163A>C	gnomAD
COSM3820175	p.Glu1394Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63420162G>A	NCI-TCGA Cosmic
rs751268334	p.Glu1396Gln	missense variant	-	NC_000017.11:g.63420168G>C	ExAC,gnomAD
rs1212542665	p.Pro1397Leu	missense variant	-	NC_000017.11:g.63420172C>T	TOPMed,gnomAD
rs780968730	p.Gln1400Lys	missense variant	-	NC_000017.11:g.63420180C>A	ExAC,gnomAD
rs1211695431	p.Asp1403Val	missense variant	-	NC_000017.11:g.63420190A>T	gnomAD
rs1283931778	p.Asp1403Asn	missense variant	-	NC_000017.11:g.63420189G>A	TOPMed
rs1282648406	p.Ile1404Val	missense variant	-	NC_000017.11:g.63420192A>G	gnomAD
rs1282648406	p.Ile1404Leu	missense variant	-	NC_000017.11:g.63420192A>C	gnomAD
rs1223480044	p.Ile1404Met	missense variant	-	NC_000017.11:g.63420194A>G	TOPMed
rs748153191	p.Tyr1405His	missense variant	-	NC_000017.11:g.63420195T>C	ExAC,TOPMed,gnomAD
rs769422542	p.Ser1406Tyr	missense variant	-	NC_000017.11:g.63420199C>A	ExAC,gnomAD
rs550952516	p.Val1407Ile	missense variant	-	NC_000017.11:g.63420201G>A	1000Genomes,ExAC,gnomAD
rs550952516	p.Val1407Leu	missense variant	-	NC_000017.11:g.63420201G>C	1000Genomes,ExAC,gnomAD
rs748823330	p.Gln1408Arg	missense variant	-	NC_000017.11:g.63420205A>G	ExAC,TOPMed,gnomAD
rs1031992264	p.Asp1409Val	missense variant	-	NC_000017.11:g.63420208A>T	TOPMed
rs563476758	p.Asp1409Asn	missense variant	-	NC_000017.11:g.63420207G>A	1000Genomes,ExAC,gnomAD
rs554718490	p.Ile1410Met	missense variant	-	NC_000017.11:g.63420212A>G	TOPMed
rs774084886	p.Ile1410Val	missense variant	-	NC_000017.11:g.63420210A>G	ExAC,TOPMed,gnomAD
rs759788253	p.Glu1412Lys	missense variant	-	NC_000017.11:g.63420216G>A	ExAC,gnomAD
rs1176061576	p.Glu1412Asp	missense variant	-	NC_000017.11:g.63420218G>T	gnomAD
rs772540956	p.Glu1413Gly	missense variant	-	NC_000017.11:g.63420220A>G	ExAC,gnomAD
rs1399495646	p.Glu1413Lys	missense variant	-	NC_000017.11:g.63420219G>A	TOPMed,gnomAD
rs1295790447	p.Tyr1415His	missense variant	-	NC_000017.11:g.63420225T>C	TOPMed
rs1318596647	p.Leu1416Gln	missense variant	-	NC_000017.11:g.63420229T>A	gnomAD
rs369743122	p.Asp1419Gly	missense variant	-	NC_000017.11:g.63420238A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs369743122	p.Asp1419Ala	missense variant	-	NC_000017.11:g.63420238A>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs761240342	p.Val1420Phe	missense variant	-	NC_000017.11:g.63420240G>T	ExAC,gnomAD
rs761240342	p.Val1420Ile	missense variant	-	NC_000017.11:g.63420240G>A	ExAC,gnomAD
NCI-TCGA novel	p.Glu1421Lys	missense variant	-	NC_000017.11:g.63420243G>A	NCI-TCGA
rs761908937	p.Ser1424Pro	missense variant	-	NC_000017.11:g.63420252T>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ile1425Val	missense variant	-	NC_000017.11:g.63420255A>G	NCI-TCGA
rs750702865	p.Ile1425Thr	missense variant	-	NC_000017.11:g.63420256T>C	ExAC,TOPMed,gnomAD
rs754716210	p.Gly1426Ala	missense variant	-	NC_000017.11:g.63420259G>C	ExAC,gnomAD
rs781107754	p.Gln1428His	missense variant	-	NC_000017.11:g.63420266G>T	ExAC,gnomAD
rs190686099	p.Thr1429Ile	missense variant	-	NC_000017.11:g.63420268C>T	1000Genomes,ExAC,TOPMed
rs190686099	p.Thr1429Lys	missense variant	-	NC_000017.11:g.63420268C>A	1000Genomes,ExAC,TOPMed
rs1396912850	p.Ala1431Asp	missense variant	-	NC_000017.11:g.63420274C>A	gnomAD
rs748768315	p.Arg1432Gln	missense variant	-	NC_000017.11:g.63420277G>A	ExAC,TOPMed,gnomAD
rs756059493	p.Arg1432Trp	missense variant	-	NC_000017.11:g.63420276C>T	ExAC,TOPMed,gnomAD
rs756059493	p.Arg1432Gly	missense variant	-	NC_000017.11:g.63420276C>G	ExAC,TOPMed,gnomAD
rs1196099411	p.Ser1434Asn	missense variant	-	NC_000017.11:g.63420283G>A	gnomAD
rs1477419551	p.Gln1435Arg	missense variant	-	NC_000017.11:g.63420286A>G	gnomAD
rs1376384903	p.Gln1435Glu	missense variant	-	NC_000017.11:g.63420285C>G	gnomAD
rs756832425	p.Gly1436Arg	missense variant	-	NC_000017.11:g.63420288G>A	ExAC,gnomAD
rs778412023	p.Gly1436Glu	missense variant	-	NC_000017.11:g.63420289G>A	ExAC,gnomAD
rs745596388	p.Leu1437Ile	missense variant	-	NC_000017.11:g.63420291C>A	ExAC,TOPMed,gnomAD
rs534775694	p.Pro1438Leu	missense variant	-	NC_000017.11:g.63420295C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs1319460082	p.Pro1438Ser	missense variant	-	NC_000017.11:g.63420294C>T	gnomAD
rs534775694	p.Pro1438Arg	missense variant	-	NC_000017.11:g.63420295C>G	1000Genomes,ExAC,TOPMed,gnomAD
rs777159927	p.Val1439Gly	missense variant	-	NC_000017.11:g.63420298T>G	ExAC,gnomAD
rs1016233271	p.Val1439Leu	missense variant	-	NC_000017.11:g.63420297G>C	TOPMed
rs1232644172	p.Gln1441Arg	missense variant	-	NC_000017.11:g.63420304A>G	gnomAD
rs765416142	p.Pro1444Arg	missense variant	-	NC_000017.11:g.63420313C>G	ExAC,gnomAD
rs1299603665	p.Ser1445Phe	missense variant	-	NC_000017.11:g.63420316C>T	gnomAD
rs1396809768	p.Pro1447Ser	missense variant	-	NC_000017.11:g.63420321C>T	TOPMed,gnomAD
rs763167667	p.Pro1447Leu	missense variant	-	NC_000017.11:g.63420322C>T	ExAC,gnomAD
rs756006150	p.Pro1448Gln	missense variant	-	NC_000017.11:g.63420325C>A	ExAC,gnomAD
rs756006150	p.Pro1448Leu	missense variant	-	NC_000017.11:g.63420325C>T	ExAC,gnomAD
rs756006150	p.Pro1448Arg	missense variant	-	NC_000017.11:g.63420325C>G	ExAC,gnomAD
rs756712907	p.His1449Arg	missense variant	-	NC_000017.11:g.63420328A>G	ExAC,gnomAD
rs778555688	p.Arg1450Trp	missense variant	-	NC_000017.11:g.63420330C>T	ExAC,TOPMed,gnomAD
rs370919725	p.Arg1450Gln	missense variant	-	NC_000017.11:g.63420331G>A	ESP,ExAC,TOPMed,gnomAD
rs1183156540	p.Asp1451Asn	missense variant	-	NC_000017.11:g.63420333G>A	gnomAD
rs898469016	p.Ser1452Thr	missense variant	-	NC_000017.11:g.63420336T>A	TOPMed
rs931307124	p.Ser1452Ter	stop gained	-	NC_000017.11:g.63420337C>G	TOPMed
rs758013067	p.Ala1453Val	missense variant	-	NC_000017.11:g.63420340C>T	ExAC,gnomAD
rs1365098541	p.Ala1453Thr	missense variant	-	NC_000017.11:g.63420339G>A	gnomAD
NCI-TCGA novel	p.Tyr1454Asp	missense variant	-	NC_000017.11:g.63420342T>G	NCI-TCGA
rs1158019912	p.Tyr1454Phe	missense variant	-	NC_000017.11:g.63420343A>T	TOPMed,gnomAD
rs747340136	p.Ile1455Thr	missense variant	-	NC_000017.11:g.63420346T>C	ExAC
rs779709993	p.Ile1455Val	missense variant	-	NC_000017.11:g.63420345A>G	ExAC,TOPMed,gnomAD
rs370812156	p.Ser1457Gly	missense variant	-	NC_000017.11:g.63420351A>G	ESP,TOPMed
NCI-TCGA novel	p.Ser1458Thr	missense variant	-	NC_000017.11:g.63420354T>A	NCI-TCGA
rs201876209	p.Leu1460Val	missense variant	-	NC_000017.11:g.63420360C>G	TOPMed
rs777104988	p.Gln1464Lys	missense variant	-	NC_000017.11:g.63420372C>A	ExAC,gnomAD
NCI-TCGA novel	p.Phe1466Cys	missense variant	-	NC_000017.11:g.63420379T>G	NCI-TCGA
rs748756535	p.Asp1467Tyr	missense variant	-	NC_000017.11:g.63420381G>T	ExAC
rs1219693183	p.Phe1468Leu	missense variant	-	NC_000017.11:g.63420386C>A	TOPMed
rs374716902	p.Arg1469Leu	missense variant	-	NC_000017.11:g.63420388G>T	ESP,ExAC,TOPMed,gnomAD
rs1287988148	p.Arg1469Trp	missense variant	-	NC_000017.11:g.63420387C>T	TOPMed,gnomAD
rs374716902	p.Arg1469Gln	missense variant	-	NC_000017.11:g.63420388G>A	ESP,ExAC,TOPMed,gnomAD
rs1247445635	p.Ser1473Phe	missense variant	-	NC_000017.11:g.63420400C>T	gnomAD
NCI-TCGA novel	p.Ser1473Tyr	missense variant	-	NC_000017.11:g.63420400C>A	NCI-TCGA
rs1295564361	p.Gly1475Ala	missense variant	-	NC_000017.11:g.63420406G>C	gnomAD
rs1200913336	p.Pro1477Ser	missense variant	-	NC_000017.11:g.63420411C>T	TOPMed
rs762966526	p.Pro1477Leu	missense variant	-	NC_000017.11:g.63420412C>T	ExAC,gnomAD
rs1254559421	p.Arg1479Thr	missense variant	-	NC_000017.11:g.63420418G>C	gnomAD
rs764041869	p.Gln1483Glu	missense variant	-	NC_000017.11:g.63420429C>G	ExAC,gnomAD
rs1257800660	p.Ser1484Cys	missense variant	-	NC_000017.11:g.63420433C>G	gnomAD
rs753826605	p.Thr1485Pro	missense variant	-	NC_000017.11:g.63420435A>C	ExAC,TOPMed,gnomAD
rs1438330151	p.Thr1485Ile	missense variant	-	NC_000017.11:g.63420436C>T	TOPMed
rs376340189	p.Pro1487Leu	missense variant	-	NC_000017.11:g.63420442C>T	ESP,ExAC,TOPMed,gnomAD
rs1184957074	p.Pro1487Ser	missense variant	-	NC_000017.11:g.63420441C>T	gnomAD
rs1462275959	p.Ala1488Val	missense variant	-	NC_000017.11:g.63420445C>T	gnomAD
rs749905545	p.Ser1496Leu	missense variant	-	NC_000017.11:g.63420469C>T	ExAC,TOPMed,gnomAD
rs779654816	p.His1497Tyr	missense variant	-	NC_000017.11:g.63420471C>T	ExAC,gnomAD
rs779654816	p.His1497Asn	missense variant	-	NC_000017.11:g.63420471C>A	ExAC,gnomAD
rs1356168073	p.Tyr1498His	missense variant	-	NC_000017.11:g.63420474T>C	gnomAD
rs1310824455	p.Arg1499Lys	missense variant	-	NC_000017.11:g.63420478G>A	gnomAD
rs1352706759	p.Pro1500Arg	missense variant	-	NC_000017.11:g.63420481C>G	TOPMed
rs1352706759	p.Pro1500Leu	missense variant	-	NC_000017.11:g.63420481C>T	TOPMed
rs1414936781	p.Pro1503Leu	missense variant	-	NC_000017.11:g.63420490C>T	TOPMed
rs571360967	p.Thr1505Ile	missense variant	-	NC_000017.11:g.63420496C>T	1000Genomes,ExAC,gnomAD
rs748473534	p.Ser1506Phe	missense variant	-	NC_000017.11:g.63420499C>T	ExAC,gnomAD
rs748473534	p.Ser1506Cys	missense variant	-	NC_000017.11:g.63420499C>G	ExAC,gnomAD
rs1277428042	p.Pro1507Ser	missense variant	-	NC_000017.11:g.63420501C>T	gnomAD
rs902412126	p.Pro1507Leu	missense variant	-	NC_000017.11:g.63420502C>T	TOPMed
rs747152020	p.His1509Tyr	missense variant	-	NC_000017.11:g.63420507C>T	ExAC,gnomAD
NCI-TCGA novel	p.Gln1510Leu	inframe deletion	-	NC_000017.11:g.63420511_63420528AGGGAGGATCTTACCGTT>-	NCI-TCGA
NCI-TCGA novel	p.Gly1512Arg	missense variant	-	NC_000017.11:g.63420516G>A	NCI-TCGA
NCI-TCGA novel	p.Ser1513Phe	missense variant	-	NC_000017.11:g.63420520C>T	NCI-TCGA
rs368429977	p.Arg1515His	missense variant	-	NC_000017.11:g.63420526G>A	ESP,ExAC,TOPMed,gnomAD
rs771184998	p.Arg1515Gly	missense variant	-	NC_000017.11:g.63420525C>G	ExAC,gnomAD
rs771184998	p.Arg1515Cys	missense variant	-	NC_000017.11:g.63420525C>T	ExAC,gnomAD
rs765187847	p.Pro1519Leu	missense variant	-	NC_000017.11:g.63420538C>T	ExAC,TOPMed,gnomAD
rs765187847	p.Pro1519His	missense variant	-	NC_000017.11:g.63420538C>A	ExAC,TOPMed,gnomAD
rs765187847	p.Pro1519Arg	missense variant	-	NC_000017.11:g.63420538C>G	ExAC,TOPMed,gnomAD
COSM1385128	p.Pro1519LeuPheSerTerUnkUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63420533C>-	NCI-TCGA Cosmic
rs776432017	p.Pro1519Ala	missense variant	-	NC_000017.11:g.63420537C>G	ExAC,TOPMed,gnomAD
rs776432017	p.Pro1519Ser	missense variant	-	NC_000017.11:g.63420537C>T	ExAC,TOPMed,gnomAD
rs776432017	p.Pro1519Thr	missense variant	-	NC_000017.11:g.63420537C>A	ExAC,TOPMed,gnomAD
rs750373872	p.Val1521Ala	missense variant	-	NC_000017.11:g.63420544T>C	ExAC,gnomAD
rs1388250674	p.Val1521Met	missense variant	-	NC_000017.11:g.63420543G>A	gnomAD
rs1301352485	p.Gly1525Ser	missense variant	-	NC_000017.11:g.63420555G>A	gnomAD
rs372102144	p.Lys1526Arg	missense variant	-	NC_000017.11:g.63420559A>G	ESP,ExAC,TOPMed,gnomAD
rs780844680	p.Ser1530Asn	missense variant	-	NC_000017.11:g.63420571G>A	ExAC,TOPMed,gnomAD
rs780844680	p.Ser1530Ile	missense variant	-	NC_000017.11:g.63420571G>T	ExAC,TOPMed,gnomAD
rs753068166	p.Pro1531Ser	missense variant	-	NC_000017.11:g.63420573C>T	ExAC,TOPMed,gnomAD
rs749820274	p.Pro1533Leu	missense variant	-	NC_000017.11:g.63420580C>T	ExAC,TOPMed,gnomAD
rs749820274	p.Pro1533His	missense variant	-	NC_000017.11:g.63420580C>A	ExAC,TOPMed,gnomAD
rs756478162	p.Pro1533Ala	missense variant	-	NC_000017.11:g.63420579C>G	ExAC,TOPMed,gnomAD
rs756478162	p.Pro1533Thr	missense variant	-	NC_000017.11:g.63420579C>A	ExAC,TOPMed,gnomAD
rs866965328	p.Pro1535Ser	missense variant	-	NC_000017.11:g.63420585C>T	TOPMed,gnomAD
rs200623978	p.Leu1536Val	missense variant	-	NC_000017.11:g.63420588C>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs545572702	p.Arg1537Gln	missense variant	-	NC_000017.11:g.63420592G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs367973706	p.Arg1537Trp	missense variant	-	NC_000017.11:g.63420591C>T	ESP,ExAC,TOPMed,gnomAD
rs367973706	p.Arg1537Gly	missense variant	-	NC_000017.11:g.63420591C>G	ESP,ExAC,TOPMed,gnomAD
rs1194230794	p.Pro1540Arg	missense variant	-	NC_000017.11:g.63420601C>G	gnomAD
rs769530509	p.Arg1543Gly	missense variant	-	NC_000017.11:g.63420609C>G	ExAC,gnomAD
rs769530509	p.Arg1543Trp	missense variant	-	NC_000017.11:g.63420609C>T	ExAC,gnomAD
rs773193935	p.Arg1543Gln	missense variant	-	NC_000017.11:g.63420610G>A	ExAC,TOPMed,gnomAD
rs1377293496	p.Ala1544Thr	missense variant	-	NC_000017.11:g.63420612G>A	gnomAD
rs1049785318	p.Ala1544Val	missense variant	-	NC_000017.11:g.63420613C>T	TOPMed
rs1460703029	p.Pro1546Ser	missense variant	-	NC_000017.11:g.63420618C>T	TOPMed,gnomAD
rs553213380	p.Pro1547Ser	missense variant	-	NC_000017.11:g.63420621C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs553213380	p.Pro1547Ala	missense variant	-	NC_000017.11:g.63420621C>G	1000Genomes,ExAC,TOPMed,gnomAD
rs944158607	p.Ala1548Thr	missense variant	-	NC_000017.11:g.63420624G>A	TOPMed,gnomAD
rs1041544504	p.Ser1550Asn	missense variant	-	NC_000017.11:g.63420631G>A	TOPMed
rs767168489	p.Ser1550Gly	missense variant	-	NC_000017.11:g.63420630A>G	ExAC,gnomAD
rs374665587	p.Met1551Leu	missense variant	-	NC_000017.11:g.63420633A>C	ESP,ExAC,TOPMed,gnomAD
rs1216969359	p.Met1551Ile	missense variant	-	NC_000017.11:g.63420635G>C	gnomAD
rs1286069399	p.Val1553Ile	missense variant	-	NC_000017.11:g.63420639G>A	TOPMed
rs756488036	p.Tyr1554Phe	missense variant	-	NC_000017.11:g.63420643A>T	ExAC,TOPMed,gnomAD
rs756488036	p.Tyr1554Cys	missense variant	-	NC_000017.11:g.63420643A>G	ExAC,TOPMed,gnomAD
rs1316972455	p.Arg1555Gly	missense variant	-	NC_000017.11:g.63420645A>G	gnomAD
rs764433252	p.Ser1556Ala	missense variant	-	NC_000017.11:g.63420648T>G	ExAC,gnomAD
rs1328260134	p.Gln1557Arg	missense variant	-	NC_000017.11:g.63420652A>G	gnomAD
rs754237687	p.Gln1557Lys	missense variant	-	NC_000017.11:g.63420651C>A	ExAC,gnomAD
rs1314749864	p.Gly1559Cys	missense variant	-	NC_000017.11:g.63420657G>T	TOPMed
NCI-TCGA novel	p.Gly1559ValPheSerTerUnkUnk	frameshift	-	NC_000017.11:g.63420658_63420659GT>-	NCI-TCGA
NCI-TCGA novel	p.Pro1561Leu	missense variant	-	NC_000017.11:g.63420664C>T	NCI-TCGA
rs368956259	p.Val1562Met	missense variant	-	NC_000017.11:g.63420666G>A	ESP,ExAC,TOPMed,gnomAD
rs373436341	p.Arg1563Cys	missense variant	-	NC_000017.11:g.63420669C>T	ESP,ExAC,TOPMed,gnomAD
rs758597698	p.Arg1563Leu	missense variant	-	NC_000017.11:g.63420670G>T	ExAC,TOPMed,gnomAD
rs758597698	p.Arg1563His	missense variant	-	NC_000017.11:g.63420670G>A	ExAC,TOPMed,gnomAD
rs1441015451	p.Tyr1564Asp	missense variant	-	NC_000017.11:g.63420672T>G	gnomAD
rs780306862	p.Gln1565Arg	missense variant	-	NC_000017.11:g.63420676A>G	ExAC,gnomAD
rs747257403	p.Gln1565His	missense variant	-	NC_000017.11:g.63420677G>T	ExAC,gnomAD
rs1457054156	p.Thr1568Ala	missense variant	-	NC_000017.11:g.63420684A>G	TOPMed,gnomAD
rs768924519	p.Thr1568Ile	missense variant	-	NC_000017.11:g.63420685C>T	ExAC,gnomAD
rs954884795	p.Ser1569Ile	missense variant	-	NC_000017.11:g.63420688G>T	TOPMed,gnomAD
rs199869842	p.Val1570Ile	missense variant	-	NC_000017.11:g.63420690G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs774310780	p.Gly1575Val	missense variant	-	NC_000017.11:g.63420706G>T	ExAC,gnomAD
rs545154452	p.Gly1575Ser	missense variant	-	NC_000017.11:g.63420705G>A	1000Genomes,ExAC,gnomAD
rs1165942036	p.Ser1579Pro	missense variant	-	NC_000017.11:g.63420717T>C	TOPMed
rs1011861731	p.Pro1580Ser	missense variant	-	NC_000017.11:g.63420720C>T	TOPMed
rs766994994	p.Leu1581Ser	missense variant	-	NC_000017.11:g.63420724T>C	ExAC,TOPMed,gnomAD
rs1263344336	p.Met1584Thr	missense variant	-	NC_000017.11:g.63420733T>C	TOPMed
rs1478421654	p.Met1584Val	missense variant	-	NC_000017.11:g.63420732A>G	TOPMed
rs775205713	p.Arg1587Gln	missense variant	-	NC_000017.11:g.63420742G>A	ExAC,TOPMed,gnomAD
rs1233680392	p.Arg1587Trp	missense variant	-	NC_000017.11:g.63420741C>T	TOPMed,gnomAD
rs1259723239	p.Pro1588Ser	missense variant	-	NC_000017.11:g.63420744C>T	TOPMed
rs1003264700	p.Pro1588Leu	missense variant	-	NC_000017.11:g.63420745C>T	TOPMed,gnomAD
rs180736177	p.Tyr1589His	missense variant	-	NC_000017.11:g.63420747T>C	1000Genomes,TOPMed,gnomAD
rs199734433	p.Val1596Glu	missense variant	-	NC_000017.11:g.63420769T>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Val1596Ala	missense variant	-	NC_000017.11:g.63420769T>C	NCI-TCGA
rs199734433	p.Val1596Gly	missense variant	-	NC_000017.11:g.63420769T>G	ExAC,TOPMed,gnomAD
COSM982560	p.Gln1600Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63420781A>G	NCI-TCGA Cosmic
rs1472423207	p.Gln1601Lys	missense variant	-	NC_000017.11:g.63420783C>A	gnomAD
COSM982562	p.Gln1601Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63420784A>G	NCI-TCGA Cosmic
NCI-TCGA novel	p.Gly1602Arg	missense variant	-	NC_000017.11:g.63420786G>A	NCI-TCGA
rs751023721	p.Arg1604Gly	missense variant	-	NC_000017.11:g.63420792A>G	ExAC,gnomAD
rs758495961	p.Gln1606Ter	stop gained	-	NC_000017.11:g.63420798C>T	ExAC,gnomAD
rs972936059	p.Ala1608Ser	missense variant	-	NC_000017.11:g.63420804G>T	TOPMed,gnomAD
rs1164732977	p.Ala1608Val	missense variant	-	NC_000017.11:g.63420805C>T	gnomAD
rs1305570834	p.Ala1610Gly	missense variant	-	NC_000017.11:g.63420811C>G	gnomAD
rs1349336732	p.Gln1611His	missense variant	-	NC_000017.11:g.63420815G>T	TOPMed,gnomAD
COSM3820179	p.Ile1612Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63420817T>C	NCI-TCGA Cosmic
rs369696442	p.Ile1612Ser	missense variant	-	NC_000017.11:g.63420817T>G	ESP,ExAC,TOPMed,gnomAD
rs369696442	p.Ile1612Asn	missense variant	-	NC_000017.11:g.63420817T>A	ESP,ExAC,TOPMed,gnomAD
rs781506204	p.Asn1616Thr	missense variant	-	NC_000017.11:g.63420829A>C	ExAC,TOPMed,gnomAD
rs770762544	p.Gln1617Pro	missense variant	-	NC_000017.11:g.63420832A>C	ExAC,gnomAD
rs920166361	p.Gln1617His	missense variant	-	NC_000017.11:g.63420833G>C	TOPMed,gnomAD
rs1344139791	p.Pro1618Ala	missense variant	-	NC_000017.11:g.63420834C>G	gnomAD
rs952968706	p.Ser1619Asn	missense variant	-	NC_000017.11:g.63420838G>A	TOPMed
COSM4420555	p.Pro1620Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63420840C>T	NCI-TCGA Cosmic
rs745873428	p.Val1622Phe	missense variant	-	NC_000017.11:g.63420846G>T	ExAC,gnomAD
rs745873428	p.Val1622Ile	missense variant	-	NC_000017.11:g.63420846G>A	ExAC,gnomAD
COSM982564	p.Ser1625Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63420856G>A	NCI-TCGA Cosmic
rs774809700	p.Thr1626Ile	missense variant	-	NC_000017.11:g.63420859C>T	ExAC
rs199702353	p.Val1627Phe	missense variant	-	NC_000017.11:g.63420861G>T	ESP,ExAC,TOPMed,gnomAD
rs199702353	p.Val1627Ile	missense variant	-	NC_000017.11:g.63420861G>A	ESP,ExAC,TOPMed,gnomAD
COSM982566	p.Ile1628Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63420865T>C	NCI-TCGA Cosmic
rs1472028693	p.Ile1628Val	missense variant	-	NC_000017.11:g.63420864A>G	gnomAD
rs1260649655	p.Gly1631Arg	missense variant	-	NC_000017.11:g.63420873G>A	TOPMed
rs200863591	p.Ala1632Val	missense variant	-	NC_000017.11:g.63420877C>T	1000Genomes,ExAC,gnomAD
rs765761955	p.Tyr1633Cys	missense variant	-	NC_000017.11:g.63420880A>G	ExAC,gnomAD
rs750818315	p.Val1636Ile	missense variant	-	NC_000017.11:g.63420888G>A	ExAC,gnomAD
rs1191455772	p.His1638Tyr	missense variant	-	NC_000017.11:g.63420894C>T	TOPMed
rs377361135	p.His1638Arg	missense variant	-	NC_000017.11:g.63420895A>G	ESP,ExAC,TOPMed,gnomAD
rs76448506	p.Ser1639Ter	stop gained	-	NC_000017.11:g.63420898C>A	-
rs766931239	p.Met1640Arg	missense variant	-	NC_000017.11:g.63420901T>G	ExAC,gnomAD
NCI-TCGA novel	p.Ala1641Ser	missense variant	-	NC_000017.11:g.63420903G>T	NCI-TCGA
rs369166403	p.Ser1642Asn	missense variant	-	NC_000017.11:g.63420907G>A	ESP,TOPMed,gnomAD
rs369166403	p.Ser1642Ile	missense variant	-	NC_000017.11:g.63420907G>T	ESP,TOPMed,gnomAD
rs916458760	p.Lys1643Gln	missense variant	-	NC_000017.11:g.63420909A>C	gnomAD
rs949345388	p.Tyr1644Ser	missense variant	-	NC_000017.11:g.63420913A>C	TOPMed
rs751552501	p.Gln1645Arg	missense variant	-	NC_000017.11:g.63420916A>G	ExAC,TOPMed,gnomAD
rs200437129	p.Gln1645His	missense variant	-	NC_000017.11:g.63420917G>C	1000Genomes
rs1259852581	p.Ser1646Thr	missense variant	-	NC_000017.11:g.63420918T>A	TOPMed
rs752976774	p.Gly1649Arg	missense variant	-	NC_000017.11:g.63420927G>A	ExAC,TOPMed,gnomAD
rs752976774	p.Gly1649Arg	missense variant	-	NC_000017.11:g.63420927G>C	ExAC,TOPMed,gnomAD
rs757042329	p.Asp1650Asn	missense variant	-	NC_000017.11:g.63420930G>A	ExAC,TOPMed,gnomAD
rs200847109	p.Ile1651Thr	missense variant	-	NC_000017.11:g.63420934T>C	ESP,ExAC,TOPMed,gnomAD
rs745692639	p.Arg1657Trp	missense variant	-	NC_000017.11:g.63420951C>T	ExAC,gnomAD
rs771860241	p.Arg1657Gln	missense variant	-	NC_000017.11:g.63420952G>A	ExAC,TOPMed,gnomAD
rs771860241	p.Arg1657Pro	missense variant	-	NC_000017.11:g.63420952G>C	ExAC,TOPMed,gnomAD
rs377391067	p.Leu1658Val	missense variant	-	NC_000017.11:g.63420954T>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs746472611	p.Val1659Asp	missense variant	-	NC_000017.11:g.63420958T>A	ExAC,TOPMed,gnomAD
rs761462464	p.Ser1663Thr	missense variant	-	NC_000017.11:g.63420969T>A	ExAC,gnomAD
rs370440994	p.Ile1664Phe	missense variant	-	NC_000017.11:g.63420972A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs377743142	p.Ile1664Thr	missense variant	-	NC_000017.11:g.63420973T>C	1000Genomes,ExAC,TOPMed,gnomAD
rs370440994	p.Ile1664Val	missense variant	-	NC_000017.11:g.63420972A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs376064282	p.Gly1665Arg	missense variant	-	NC_000017.11:g.63420975G>A	ESP,ExAC,TOPMed,gnomAD
rs773661768	p.Gly1666Glu	missense variant	-	NC_000017.11:g.63420979G>A	ExAC,gnomAD
rs201027730	p.Val1668Leu	missense variant	-	NC_000017.11:g.63420984G>C	ESP,ExAC,TOPMed,gnomAD
rs201027730	p.Val1668Ile	missense variant	-	NC_000017.11:g.63420984G>A	ESP,ExAC,TOPMed,gnomAD
rs759160811	p.Val1668Ala	missense variant	-	NC_000017.11:g.63420985T>C	gnomAD
rs201027730	p.Val1668Leu	missense variant	-	NC_000017.11:g.63420984G>T	ESP,ExAC,TOPMed,gnomAD
rs1276755136	p.Gly1669Arg	missense variant	-	NC_000017.11:g.63420987G>A	gnomAD
COSM473172	p.Asp1670Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63420990G>A	NCI-TCGA Cosmic
rs767652053	p.Arg1672Lys	missense variant	-	NC_000017.11:g.63420997G>A	ExAC,gnomAD
rs752778741	p.Pro1673Leu	missense variant	-	NC_000017.11:g.63421000C>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Gln1678Lys	missense variant	-	NC_000017.11:g.63421014C>A	NCI-TCGA
rs750149145	p.Ala1679Gly	missense variant	-	NC_000017.11:g.63421018C>G	ExAC,TOPMed,gnomAD
rs750149145	p.Ala1679Val	missense variant	-	NC_000017.11:g.63421018C>T	ExAC,TOPMed,gnomAD
rs1207165448	p.Ala1679Pro	missense variant	-	NC_000017.11:g.63421017G>C	gnomAD
rs1452758263	p.Leu1681Val	missense variant	-	NC_000017.11:g.63421023C>G	gnomAD
rs1256732461	p.Ser1682Arg	missense variant	-	NC_000017.11:g.63421026A>C	TOPMed
rs758256144	p.Ser1682Thr	missense variant	-	NC_000017.11:g.63421027G>C	ExAC,gnomAD
rs1244521868	p.Ala1683Val	missense variant	-	NC_000017.11:g.63421030C>T	gnomAD
rs567268087	p.Ala1685Thr	missense variant	-	NC_000017.11:g.63421035G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs1302894077	p.Cys1687Phe	missense variant	-	NC_000017.11:g.63421042G>T	TOPMed
rs368631067	p.His1689Gln	missense variant	-	NC_000017.11:g.63421049T>A	ESP,ExAC,gnomAD
COSM3520620	p.Lys1694Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421063A>T	NCI-TCGA Cosmic
rs1455455651	p.Asp1696Val	missense variant	-	NC_000017.11:g.63421069A>T	gnomAD
rs780787900	p.Leu1697Pro	missense variant	-	NC_000017.11:g.63421072T>C	ExAC,gnomAD
rs769530798	p.Pro1698Ala	missense variant	-	NC_000017.11:g.63421074C>G	ExAC,TOPMed,gnomAD
rs769530798	p.Pro1698Thr	missense variant	-	NC_000017.11:g.63421074C>A	ExAC,TOPMed,gnomAD
rs773039687	p.Pro1698Arg	missense variant	-	NC_000017.11:g.63421075C>G	ExAC,gnomAD
rs749592806	p.Arg1700Gln	missense variant	-	NC_000017.11:g.63421081G>A	ExAC,gnomAD
NCI-TCGA novel	p.Ser1703Leu	missense variant	-	NC_000017.11:g.63421090C>T	NCI-TCGA
rs774717697	p.Ala1704Val	missense variant	-	NC_000017.11:g.63421093C>T	ExAC,gnomAD
rs771384486	p.Ala1704Ser	missense variant	-	NC_000017.11:g.63421092G>T	ExAC,gnomAD
rs1226789491	p.Tyr1705His	missense variant	-	NC_000017.11:g.63421095T>C	gnomAD
COSM562009	p.Arg1706Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63421098C>T	NCI-TCGA Cosmic
rs760022382	p.Arg1706Gln	missense variant	-	NC_000017.11:g.63421099G>A	ExAC,TOPMed,gnomAD
rs775502405	p.Gly1707Cys	missense variant	-	NC_000017.11:g.63421101G>T	ExAC,gnomAD
NCI-TCGA novel	p.Gly1707Ser	missense variant	-	NC_000017.11:g.63421101G>A	NCI-TCGA
NCI-TCGA novel	p.Gly1707Asp	missense variant	-	NC_000017.11:g.63421102G>A	NCI-TCGA
rs760778311	p.Gly1708Asp	missense variant	-	NC_000017.11:g.63421105G>A	ExAC,gnomAD
rs527348146	p.Val1709Met	missense variant	-	NC_000017.11:g.63421107G>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Tyr1711Cys	missense variant	-	NC_000017.11:g.63421114A>G	NCI-TCGA
rs1182194839	p.Tyr1711His	missense variant	-	NC_000017.11:g.63421113T>C	TOPMed,gnomAD
rs758120629	p.Ser1712Gly	missense variant	-	NC_000017.11:g.63421116A>G	ExAC,gnomAD
rs1180989630	p.Pro1715Ser	missense variant	-	NC_000017.11:g.63421125C>T	gnomAD
rs1368886723	p.Gln1716Arg	missense variant	-	NC_000017.11:g.63421129A>G	gnomAD
rs766127499	p.Ile1717Met	missense variant	-	NC_000017.11:g.63421133C>G	ExAC,TOPMed,gnomAD
COSM1228470	p.Gly1718Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421134G>A	NCI-TCGA Cosmic
rs961824372	p.Arg1719His	missense variant	-	NC_000017.11:g.63421138G>A	TOPMed,gnomAD
rs535828619	p.Arg1719Cys	missense variant	-	NC_000017.11:g.63421137C>T	1000Genomes,ExAC
COSM3520622	p.Gln1721Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63421143C>T	NCI-TCGA Cosmic
rs752209041	p.Tyr1725Cys	missense variant	-	NC_000017.11:g.63421156A>G	ExAC,TOPMed,gnomAD
rs777277066	p.His1730Pro	missense variant	-	NC_000017.11:g.63421171A>C	ExAC,TOPMed,gnomAD
rs777277066	p.His1730Leu	missense variant	-	NC_000017.11:g.63421171A>T	ExAC,TOPMed,gnomAD
rs755826725	p.Lys1732Glu	missense variant	-	NC_000017.11:g.63421176A>G	ExAC,gnomAD
rs1279663690	p.Asp1734His	missense variant	-	NC_000017.11:g.63421182G>C	TOPMed
rs145164118	p.Arg1737His	missense variant	-	NC_000017.11:g.63421192G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs911472721	p.Arg1737Cys	missense variant	-	NC_000017.11:g.63421191C>T	TOPMed
rs145164118	p.Arg1737Pro	missense variant	-	NC_000017.11:g.63421192G>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs949289102	p.Ser1738Pro	missense variant	-	NC_000017.11:g.63421194T>C	TOPMed
rs760725301	p.Ser1739Ala	missense variant	-	NC_000017.11:g.63421197T>G	ExAC,gnomAD
rs776573587	p.Ser1740Gly	missense variant	-	NC_000017.11:g.63421200A>G	ExAC,TOPMed,gnomAD
rs762033674	p.Ser1740Thr	missense variant	-	NC_000017.11:g.63421201G>C	ExAC,gnomAD
rs754859782	p.Gly1743Val	missense variant	-	NC_000017.11:g.63421210G>T	ExAC,gnomAD
rs754859782	p.Gly1743Ala	missense variant	-	NC_000017.11:g.63421210G>C	ExAC,gnomAD
rs754859782	p.Gly1743Asp	missense variant	-	NC_000017.11:g.63421210G>A	ExAC,gnomAD
rs767537932	p.Ser1744Phe	missense variant	-	NC_000017.11:g.63421213C>T	ExAC,gnomAD
rs1311730519	p.Pro1745Ser	missense variant	-	NC_000017.11:g.63421215C>T	TOPMed
rs752740180	p.Ser1748Ala	missense variant	-	NC_000017.11:g.63421224T>G	ExAC,gnomAD
rs756992729	p.Ser1748Ter	stop gained	-	NC_000017.11:g.63421225C>A	TOPMed,gnomAD
rs756992729	p.Ser1748Leu	missense variant	-	NC_000017.11:g.63421225C>T	TOPMed,gnomAD
NCI-TCGA novel	p.His1749Arg	missense variant	-	NC_000017.11:g.63421228A>G	NCI-TCGA
rs777271783	p.Arg1752Gly	missense variant	-	NC_000017.11:g.63421236A>G	ExAC,gnomAD
rs1297843133	p.Arg1753Thr	missense variant	-	NC_000017.11:g.63421240G>C	gnomAD
rs748761784	p.Ile1755Val	missense variant	-	NC_000017.11:g.63421245A>G	ExAC,gnomAD
rs756887497	p.Ser1756Gly	missense variant	-	NC_000017.11:g.63421248A>G	ExAC,gnomAD
rs1469394377	p.Val1757Asp	missense variant	-	NC_000017.11:g.63421252T>A	TOPMed
rs1369020821	p.Asn1758Ile	missense variant	-	NC_000017.11:g.63421255A>T	TOPMed
rs746202328	p.Pro1759Arg	missense variant	-	NC_000017.11:g.63421258C>G	ExAC,TOPMed,gnomAD
rs746202328	p.Pro1759His	missense variant	-	NC_000017.11:g.63421258C>A	ExAC,TOPMed,gnomAD
rs780529896	p.Asn1760Lys	missense variant	-	NC_000017.11:g.63421262C>G	ExAC,TOPMed,gnomAD
COSM3520624	p.Glu1761Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000017.11:g.63421263G>T	NCI-TCGA Cosmic
rs1256980242	p.Glu1761Lys	missense variant	-	NC_000017.11:g.63421263G>A	TOPMed
rs1286665712	p.Ile1762Met	missense variant	-	NC_000017.11:g.63421268C>G	gnomAD
rs1300406778	p.Ile1762Thr	missense variant	-	NC_000017.11:g.63421267T>C	gnomAD
rs778978586	p.Pro1764Leu	missense variant	-	NC_000017.11:g.63421273C>T	ExAC,TOPMed,gnomAD
rs1483992808	p.His1765Pro	missense variant	-	NC_000017.11:g.63421276A>C	gnomAD
rs575680050	p.His1765Tyr	missense variant	-	NC_000017.11:g.63421275C>T	1000Genomes,ExAC,gnomAD
rs200671950	p.Pro1766Leu	missense variant	-	NC_000017.11:g.63421279C>T	ESP,ExAC,TOPMed,gnomAD
rs767486546	p.Pro1771Leu	missense variant	-	NC_000017.11:g.63421294C>T	ExAC,TOPMed,gnomAD
rs1426828513	p.Leu1772Phe	missense variant	-	NC_000017.11:g.63421298G>T	gnomAD
rs745771366	p.Ser1775Phe	missense variant	-	NC_000017.11:g.63421306C>T	TOPMed,gnomAD
rs745771366	p.Ser1775Cys	missense variant	-	NC_000017.11:g.63421306C>G	TOPMed,gnomAD
rs1467826852	p.Gln1776His	missense variant	-	NC_000017.11:g.63421310A>C	gnomAD
NCI-TCGA novel	p.Ser1777Arg	missense variant	-	NC_000017.11:g.63421313T>G	NCI-TCGA
rs755096851	p.Val1778Glu	missense variant	-	NC_000017.11:g.63421315T>A	ExAC,TOPMed,gnomAD
rs369786230	p.Leu1780Phe	missense variant	-	NC_000017.11:g.63421320C>T	ESP,TOPMed,gnomAD
rs372821172	p.Arg1781His	missense variant	-	NC_000017.11:g.63421324G>A	ESP,ExAC,TOPMed,gnomAD
rs1405337100	p.Arg1781Cys	missense variant	-	NC_000017.11:g.63421323C>T	TOPMed,gnomAD
RCV000678330	p.Phe1782Cys	missense variant	-	NC_000017.11:g.63421327T>G	ClinVar
COSM982572	p.Phe1782Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421328C>A	NCI-TCGA Cosmic
rs1166814116	p.Pro1784Leu	missense variant	-	NC_000017.11:g.63421333C>T	TOPMed
COSM437103	p.Pro1784Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421332C>T	NCI-TCGA Cosmic
COSM4068539	p.Ser1786Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421340C>G	NCI-TCGA Cosmic
rs1459875529	p.Ser1786Asn	missense variant	-	NC_000017.11:g.63421339G>A	TOPMed
rs1420367914	p.Ser1788Arg	missense variant	-	NC_000017.11:g.63421346T>A	gnomAD
rs778608692	p.Ser1788Gly	missense variant	-	NC_000017.11:g.63421344A>G	ExAC,TOPMed,gnomAD
rs939023019	p.Ile1789Asn	missense variant	-	NC_000017.11:g.63421348T>A	TOPMed
rs1240396587	p.Ser1790Phe	missense variant	-	NC_000017.11:g.63421351C>T	TOPMed
rs758761101	p.Thr1792Pro	missense variant	-	NC_000017.11:g.63421356A>C	ExAC,TOPMed,gnomAD
rs1262075337	p.Thr1792Asn	missense variant	-	NC_000017.11:g.63421357C>A	gnomAD
rs1452388871	p.Ser1793Pro	missense variant	-	NC_000017.11:g.63421359T>C	TOPMed
rs780335763	p.Asn1794Lys	missense variant	-	NC_000017.11:g.63421364C>G	ExAC,gnomAD
rs747393102	p.Pro1797Arg	missense variant	-	NC_000017.11:g.63421372C>G	ExAC,TOPMed,gnomAD
rs747393102	p.Pro1797Gln	missense variant	-	NC_000017.11:g.63421372C>A	ExAC,TOPMed,gnomAD
rs747393102	p.Pro1797Leu	missense variant	-	NC_000017.11:g.63421372C>T	ExAC,TOPMed,gnomAD
rs1246120117	p.Pro1797Ser	missense variant	-	NC_000017.11:g.63421371C>T	gnomAD
NCI-TCGA novel	p.Thr1798Ala	missense variant	-	NC_000017.11:g.63421374A>G	NCI-TCGA
rs1315330686	p.Phe1799Leu	missense variant	-	NC_000017.11:g.63421379C>G	TOPMed,gnomAD
rs554732900	p.Arg1800Gln	missense variant	-	NC_000017.11:g.63421381G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs369925559	p.Pro1801Ser	missense variant	-	NC_000017.11:g.63421383C>T	ESP,ExAC,TOPMed,gnomAD
rs1458109367	p.Ile1805Met	missense variant	-	NC_000017.11:g.63421397C>G	gnomAD
NCI-TCGA novel	p.Ile1805SerPheSerTerUnk	frameshift	-	NC_000017.11:g.63421395A>-	NCI-TCGA
rs1161749012	p.Gln1806His	missense variant	-	NC_000017.11:g.63421400G>C	gnomAD
rs903333643	p.Met1808Ile	missense variant	-	NC_000017.11:g.63421406G>A	gnomAD
rs760420318	p.Glu1809Asp	missense variant	-	NC_000017.11:g.63421409G>T	ExAC,gnomAD
rs574785929	p.Glu1809Gly	missense variant	-	NC_000017.11:g.63421408A>G	1000Genomes,ExAC,gnomAD
rs764063433	p.Ile1810Phe	missense variant	-	NC_000017.11:g.63421410A>T	ExAC,gnomAD
rs753770664	p.Pro1811Thr	missense variant	-	NC_000017.11:g.63421413C>A	ExAC,TOPMed,gnomAD
rs753770664	p.Pro1811Ala	missense variant	-	NC_000017.11:g.63421413C>G	ExAC,TOPMed,gnomAD
rs761377618	p.Leu1812Pro	missense variant	-	NC_000017.11:g.63421417T>C	ExAC,gnomAD
rs764724684	p.Pro1814Ser	missense variant	-	NC_000017.11:g.63421422C>T	ExAC,gnomAD
rs757992885	p.Tyr1816Cys	missense variant	-	NC_000017.11:g.63421429A>G	ExAC,gnomAD
NCI-TCGA novel	p.Glu1817Lys	missense variant	-	NC_000017.11:g.63421431G>A	NCI-TCGA
rs373701170	p.Arg1818Lys	missense variant	-	NC_000017.11:g.63421435G>A	ESP,ExAC,gnomAD
NCI-TCGA novel	p.Ser1819Pro	missense variant	-	NC_000017.11:g.63421437T>C	NCI-TCGA
rs1489519891	p.Ser1819Ala	missense variant	-	NC_000017.11:g.63421437T>G	gnomAD
rs751887014	p.Cys1820Arg	missense variant	-	NC_000017.11:g.63421440T>C	ExAC,TOPMed,gnomAD
rs1268456704	p.Asp1821Asn	missense variant	-	NC_000017.11:g.63421443G>A	gnomAD
rs1184582533	p.Glu1822Lys	missense variant	-	NC_000017.11:g.63421446G>A	gnomAD
rs1406287301	p.Leu1823Met	missense variant	-	NC_000017.11:g.63421449C>A	gnomAD
rs748669837	p.Ser1824Leu	missense variant	-	NC_000017.11:g.63421453C>T	ExAC,gnomAD
rs1438372391	p.Val1826Ala	missense variant	-	NC_000017.11:g.63421459T>C	TOPMed
COSM3520628	p.Ser1827Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421461T>A	NCI-TCGA Cosmic
rs777943676	p.Pro1828Ser	missense variant	-	NC_000017.11:g.63421464C>T	ExAC,TOPMed,gnomAD
COSM437105	p.Thr1829Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421467A>G	NCI-TCGA Cosmic
rs1370621479	p.Gln1830Pro	missense variant	-	NC_000017.11:g.63421471A>C	gnomAD
rs1370621479	p.Gln1830Arg	missense variant	-	NC_000017.11:g.63421471A>G	gnomAD
rs1023719647	p.Gly1832Val	missense variant	-	NC_000017.11:g.63421477G>T	gnomAD
rs1023719647	p.Gly1832Asp	missense variant	-	NC_000017.11:g.63421477G>A	gnomAD
rs1286037648	p.Pro1834Thr	missense variant	-	NC_000017.11:g.63421482C>A	gnomAD
rs1372390913	p.Ser1835Thr	missense variant	-	NC_000017.11:g.63421486G>C	gnomAD
rs1372390913	p.Ser1835Asn	missense variant	-	NC_000017.11:g.63421486G>A	gnomAD
rs771240133	p.Thr1838Ile	missense variant	-	NC_000017.11:g.63421495C>T	ExAC,TOPMed,gnomAD
rs749401189	p.Thr1838Ala	missense variant	-	NC_000017.11:g.63421494A>G	ExAC,TOPMed,gnomAD
rs771240133	p.Thr1838Asn	missense variant	-	NC_000017.11:g.63421495C>A	ExAC,TOPMed,gnomAD
rs774755385	p.Arg1839Gln	missense variant	-	NC_000017.11:g.63421498G>A	ExAC,gnomAD
rs746800474	p.Ser1840Cys	missense variant	-	NC_000017.11:g.63421501C>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asp1850His	missense variant	-	NC_000017.11:g.63421530G>C	NCI-TCGA
rs768395983	p.Ala1853Val	missense variant	-	NC_000017.11:g.63421540C>T	ExAC,gnomAD
rs970401610	p.Arg1854Trp	missense variant	-	NC_000017.11:g.63421542C>T	TOPMed
NCI-TCGA novel	p.Arg1854Gln	missense variant	-	NC_000017.11:g.63421543G>A	NCI-TCGA
rs1480517152	p.Thr1855Ala	missense variant	-	NC_000017.11:g.63421545A>G	gnomAD
rs776631036	p.Gln1857His	missense variant	-	NC_000017.11:g.63421553G>T	ExAC,TOPMed,gnomAD
rs1416403749	p.Pro1859Leu	missense variant	-	NC_000017.11:g.63421558C>T	TOPMed,gnomAD
COSM3520632	p.His1860Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421560C>T	NCI-TCGA Cosmic
rs981984324	p.Leu1861Ile	missense variant	-	NC_000017.11:g.63421563C>A	TOPMed,gnomAD
rs907823428	p.Leu1861His	missense variant	-	NC_000017.11:g.63421564T>A	gnomAD
rs907823428	p.Leu1861Pro	missense variant	-	NC_000017.11:g.63421564T>C	gnomAD
rs765178482	p.Gln1864His	missense variant	-	NC_000017.11:g.63421574G>T	ExAC,gnomAD
rs1431062855	p.Gln1864Glu	missense variant	-	NC_000017.11:g.63421572C>G	gnomAD
rs989488359	p.Arg1866Gln	missense variant	-	NC_000017.11:g.63421579G>A	TOPMed,gnomAD
rs770059956	p.Arg1866Trp	missense variant	-	NC_000017.11:g.63421578C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Thr1867Ala	missense variant	-	NC_000017.11:g.63421581A>G	NCI-TCGA
rs377595755	p.Val1870Leu	missense variant	-	NC_000017.11:g.63421590G>C	ESP,ExAC,TOPMed,gnomAD
rs377595755	p.Val1870Met	missense variant	-	NC_000017.11:g.63421590G>A	ESP,ExAC,TOPMed,gnomAD
rs755364335	p.Val1873Leu	missense variant	-	NC_000017.11:g.63421599G>C	ExAC,TOPMed,gnomAD
rs753119278	p.Thr1875Ile	missense variant	-	NC_000017.11:g.63421606C>T	ExAC,gnomAD
rs1271150693	p.Val1876Ile	missense variant	-	NC_000017.11:g.63421608G>A	gnomAD
rs778455961	p.Val1876Gly	missense variant	-	NC_000017.11:g.63421609T>G	ExAC,gnomAD
rs749349700	p.Thr1880Met	missense variant	-	NC_000017.11:g.63421621C>T	ExAC,TOPMed,gnomAD
rs1249139588	p.Asn1884Ser	missense variant	-	NC_000017.11:g.63421633A>G	gnomAD
rs779267258	p.Asn1884His	missense variant	-	NC_000017.11:g.63421632A>C	ExAC,gnomAD
rs746147775	p.Asn1884Lys	missense variant	-	NC_000017.11:g.63421634C>A	ExAC,gnomAD
rs1050565017	p.Glu1889Lys	missense variant	-	NC_000017.11:g.63421647G>A	gnomAD
rs748002519	p.Pro1893Leu	missense variant	-	NC_000017.11:g.63421660C>T	ExAC,gnomAD
rs748002519	p.Pro1893Arg	missense variant	-	NC_000017.11:g.63421660C>G	ExAC,gnomAD
rs1397149525	p.Pro1894Ser	missense variant	-	NC_000017.11:g.63421662C>T	TOPMed
rs769685607	p.Pro1894Leu	missense variant	-	NC_000017.11:g.63421663C>T	ExAC,gnomAD
rs773916129	p.Ile1897Val	missense variant	-	NC_000017.11:g.63421671A>G	ExAC,gnomAD
rs1452005342	p.Ser1898Gly	missense variant	-	NC_000017.11:g.63421674A>G	gnomAD
rs370984925	p.Ala1901Thr	missense variant	-	NC_000017.11:g.63421683G>A	ESP,ExAC,gnomAD
rs754457210	p.Asn1904Ser	missense variant	-	NC_000017.11:g.63421693A>G	ExAC,gnomAD
rs1321882934	p.Asn1904Lys	missense variant	-	NC_000017.11:g.63421694C>A	gnomAD
rs757412255	p.Lys1905Glu	missense variant	-	NC_000017.11:g.63421695A>G	ExAC,gnomAD
rs375544808	p.Asn1908Ser	missense variant	-	NC_000017.11:g.63421705A>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ala1909Thr	missense variant	-	NC_000017.11:g.63421707G>A	NCI-TCGA
rs1485733982	p.Gln1910His	missense variant	-	NC_000017.11:g.63421712G>C	TOPMed
rs750533826	p.Gln1910Glu	missense variant	-	NC_000017.11:g.63421710C>G	ExAC,gnomAD
rs758505350	p.His1913Tyr	missense variant	-	NC_000017.11:g.63421719C>T	ExAC,gnomAD
rs780359922	p.Leu1914Phe	missense variant	-	NC_000017.11:g.63421724G>C	ExAC,gnomAD
rs1192588877	p.Leu1915Pro	missense variant	-	NC_000017.11:g.63421726T>C	gnomAD
COSM3520634	p.Glu1916Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421728G>A	NCI-TCGA Cosmic
rs1426698867	p.Asp1918Asn	missense variant	-	NC_000017.11:g.63421734G>A	TOPMed,gnomAD
NCI-TCGA novel	p.Asp1918Tyr	missense variant	-	NC_000017.11:g.63421734G>T	NCI-TCGA
rs747870086	p.Tyr1919His	missense variant	-	NC_000017.11:g.63421737T>C	ExAC,gnomAD
COSM982578	p.Tyr1920Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421740T>G	NCI-TCGA Cosmic
NCI-TCGA novel	p.Ser1921Ile	missense variant	-	NC_000017.11:g.63421744G>T	NCI-TCGA
rs769632418	p.His1923Arg	missense variant	-	NC_000017.11:g.63421750A>G	ExAC,gnomAD
rs777680802	p.His1923Gln	missense variant	-	NC_000017.11:g.63421751T>G	ExAC,gnomAD
rs1159713021	p.His1923Tyr	missense variant	-	NC_000017.11:g.63421749C>T	gnomAD
COSM4068543	p.Gly1924Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421753G>A	NCI-TCGA Cosmic
rs1325961295	p.Ala1927Gly	missense variant	-	NC_000017.11:g.63421762C>G	gnomAD
rs1285447111	p.Gly1929Arg	missense variant	-	NC_000017.11:g.63421767G>A	gnomAD
rs773684889	p.Gly1929Val	missense variant	-	NC_000017.11:g.63421768G>T	ExAC,gnomAD
rs759117220	p.Arg1931Cys	missense variant	-	NC_000017.11:g.63421773C>T	ExAC,gnomAD
rs370863314	p.Arg1931His	missense variant	-	NC_000017.11:g.63421774G>A	ESP,ExAC,TOPMed,gnomAD
rs370863314	p.Arg1931Pro	missense variant	-	NC_000017.11:g.63421774G>C	ESP,ExAC,TOPMed,gnomAD
rs1353264981	p.Gly1932Ala	missense variant	-	NC_000017.11:g.63421777G>C	gnomAD
rs1377406981	p.Gly1932Arg	missense variant	-	NC_000017.11:g.63421776G>A	TOPMed
rs764622235	p.Leu1934Pro	missense variant	-	NC_000017.11:g.63421783T>C	ExAC,gnomAD
NCI-TCGA novel	p.Leu1934Ile	missense variant	-	NC_000017.11:g.63421782C>A	NCI-TCGA
rs754262922	p.Glu1936Asp	missense variant	-	NC_000017.11:g.63421790G>T	ExAC,TOPMed
rs201832911	p.Arg1937Gln	missense variant	-	NC_000017.11:g.63421792G>A	1000Genomes,ExAC,gnomAD
NCI-TCGA novel	p.Val1938Asp	missense variant	-	NC_000017.11:g.63421795T>A	NCI-TCGA
rs1368922867	p.Ser1939Asn	missense variant	-	NC_000017.11:g.63421798G>A	gnomAD
rs765799716	p.Gln1940Glu	missense variant	-	NC_000017.11:g.63421800C>G	ExAC,gnomAD
rs1345945576	p.Ala1941Val	missense variant	-	NC_000017.11:g.63421804C>T	TOPMed
rs373945647	p.Ser1942Ala	missense variant	-	NC_000017.11:g.63421806T>G	ESP,ExAC,TOPMed,gnomAD
COSM3520638	p.Ser1942Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421807C>T	NCI-TCGA Cosmic
rs1189327178	p.Tyr1944Ser	missense variant	-	NC_000017.11:g.63421813A>C	TOPMed
rs1413957077	p.Pro1945Ala	missense variant	-	NC_000017.11:g.63421815C>G	TOPMed,gnomAD
rs749717844	p.Asp1946Asn	missense variant	-	NC_000017.11:g.63421818G>A	ExAC,TOPMed,gnomAD
rs771171549	p.Val1947Met	missense variant	-	NC_000017.11:g.63421821G>A	ExAC,TOPMed,gnomAD
rs771171549	p.Val1947Leu	missense variant	-	NC_000017.11:g.63421821G>C	ExAC,TOPMed,gnomAD
rs998370777	p.Lys1948Gln	missense variant	-	NC_000017.11:g.63421824A>C	TOPMed,gnomAD
rs770815483	p.Arg1951Gln	missense variant	-	NC_000017.11:g.63421834G>A	ExAC,TOPMed,gnomAD
rs778950132	p.Thr1952Ser	missense variant	-	NC_000017.11:g.63421836A>T	ExAC,gnomAD
rs1237259444	p.Leu1953Pro	missense variant	-	NC_000017.11:g.63421840T>C	gnomAD
rs367931101	p.Ala1956Val	missense variant	-	NC_000017.11:g.63421849C>T	ESP,ExAC,gnomAD
rs775003949	p.Gln1957Lys	missense variant	-	NC_000017.11:g.63421851C>A	ExAC,gnomAD
rs775003949	p.Gln1957Glu	missense variant	-	NC_000017.11:g.63421851C>G	ExAC,gnomAD
rs1289017515	p.Ala1958Thr	missense variant	-	NC_000017.11:g.63421854G>A	gnomAD
rs1490034568	p.Ala1958Glu	missense variant	-	NC_000017.11:g.63421855C>A	gnomAD
rs1253466605	p.Tyr1959His	missense variant	-	NC_000017.11:g.63421857T>C	gnomAD
rs1435881746	p.Gln1960His	missense variant	-	NC_000017.11:g.63421862G>C	gnomAD
rs768439807	p.Asn1962Ser	missense variant	-	NC_000017.11:g.63421867A>G	ExAC,gnomAD
rs777091535	p.Arg1965Lys	missense variant	-	NC_000017.11:g.63421876G>A	ExAC,gnomAD
rs1309017242	p.Leu1967Val	missense variant	-	NC_000017.11:g.63421881C>G	TOPMed,gnomAD
rs143701650	p.Arg1969Gln	missense variant	-	NC_000017.11:g.63421888G>A	1000Genomes,ExAC,gnomAD
rs1161576286	p.Arg1969Ter	stop gained	-	NC_000017.11:g.63421887C>T	gnomAD
NCI-TCGA novel	p.Ser1971Phe	missense variant	-	NC_000017.11:g.63421894C>T	NCI-TCGA
rs1308876722	p.Arg1972Gln	missense variant	-	NC_000017.11:g.63421897G>A	gnomAD
rs765636470	p.Arg1972Gly	missense variant	-	NC_000017.11:g.63421896C>G	ExAC,TOPMed,gnomAD
rs989477132	p.Gln1973Lys	missense variant	-	NC_000017.11:g.63421899C>A	TOPMed
rs1198931893	p.Ser1977Pro	missense variant	-	NC_000017.11:g.63421911T>C	gnomAD
COSM3520640	p.Ser1977Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421912C>T	NCI-TCGA Cosmic
rs867097287	p.Ile1979Val	missense variant	-	NC_000017.11:g.63421917A>G	TOPMed,gnomAD
COSM3795922	p.Ile1979Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000017.11:g.63421919C>G	NCI-TCGA Cosmic
rs1248851797	p.Lys1982Glu	missense variant	-	NC_000017.11:g.63421926A>G	gnomAD
rs1313506114	p.Arg1983Lys	missense variant	-	NC_000017.11:g.63421930G>A	gnomAD
rs1345026269	p.Pro1984Leu	missense variant	-	NC_000017.11:g.63421933C>T	TOPMed
rs1194900179	p.Phe1985Ser	missense variant	-	NC_000017.11:g.63421936T>C	gnomAD
rs755143983	p.Val1986Met	missense variant	-	NC_000017.11:g.63421938G>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asn1989MetPheSerTerUnkUnkUnk	frameshift	-	NC_000017.11:g.63421947_63421948insTGATCCCC	NCI-TCGA
rs767758030	p.Asn1989Asp	missense variant	-	NC_000017.11:g.63421947A>G	ExAC,TOPMed

Disease or phenotype associated information

Disease ID	Disease Name	Disease Type	Source
C0006142	Malignant neoplasm of breast	disease	BEFREE
C0021704	Intelligence	phenotype	GWASCAT
C0027404	Narcolepsy	disease	GWASDB
C0678222	Breast Carcinoma	disease	BEFREE
C1535926	Neurodevelopmental Disorders	group	CTD_human
C3714756	Intellectual Disability	group	GENOMICS_ENGLAND

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO ID	GO Term	Evidence

GO:Biological Process

GO ID	GO Term	Evidence
GO:0001701	in utero embryonic development	IEA
GO:0060998	regulation of dendritic spine development	ISS
GO:0061001	regulation of dendritic spine morphogenesis	ISS
GO:0099519	dense core granule cytoskeletal transport	ISS

GO:Cellular Component

GO ID	GO Term	Evidence
GO:0030054	cell junction	IEA
GO:0030424	axon	IEA
GO:0043197	dendritic spine	IDA

Reactome Pathway

Reactome ID	Reactome Term	Evidence

Drugs and compounds information

ID	Drug Name	Action	PubMed
D015655	1-Methyl-4-phenylpyridinium	1-Methyl-4-phenylpyridinium results in increased expression of TANC2 mRNA	28801915
C051246	1-methylanthracene	[1-methylanthracene co-treated with fluoranthene] results in increased expression of TANC2 mRNA	28329830
C511295	2,2',4,4'-tetrabromodiphenyl ether	2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of TANC2 mRNA	19095052
C029497	2,3-bis(3'-hydroxybenzyl)butyrolactone	[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TANC2 mRNA	19167446
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC2 mRNA	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC2 mRNA	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC2 mRNA	27188386
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TANC2 mRNA	19150397
C496492	abrine	abrine results in increased expression of TANC2 mRNA	31054353
D000082	Acetaminophen	Acetaminophen results in increased expression of TANC2 mRNA	29067470
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of TANC2 protein	20106945
C029753	aflatoxin B2	aflatoxin B2 results in decreased methylation of TANC2 intron	30157460
C029753	aflatoxin B2	aflatoxin B2 results in increased methylation of TANC2 intron	30157460
D000517	alpha-Chlorohydrin	alpha-Chlorohydrin results in increased expression of TANC2 mRNA	28522335
D000661	Amphetamine	Amphetamine results in decreased expression of TANC2 mRNA	30779732
D001151	Arsenic	Arsenic affects the methylation of TANC2 gene	25304211
D000077237	Arsenic Trioxide	Arsenic Trioxide results in increased expression of TANC2 mRNA	20458559
D001280	Atrazine	Atrazine results in decreased expression of TANC2 mRNA	25929836
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the expression of TANC2 mRNA	21714911
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the methylation of TANC2 intron	30157460
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of TANC2 mRNA	19770486
C026487	benzo(e)pyrene	benzo(e)pyrene results in increased methylation of TANC2 intron	30157460
C006780	bisphenol A	bisphenol A affects the expression of TANC2 mRNA	25181051
C006780	bisphenol A	[bisphenol A co-treated with Estradiol] results in decreased expression of TANC2 mRNA	26496021
C006780	bisphenol A	bisphenol A results in increased expression of TANC2 mRNA	29097150; 30816183;
D002945	Cisplatin	[Cisplatin co-treated with jinfukang] results in decreased expression of TANC2 mRNA	27392435
D002945	Cisplatin	Cisplatin results in decreased expression of TANC2 mRNA	19561079; 27392435;
D003375	Coumestrol	[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TANC2 mRNA	19167446
D016572	Cyclosporine	Cyclosporine results in increased expression of TANC2 mRNA	20106945
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of TANC2 mRNA	31163220
C516138	dorsomorphin	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC2 mRNA	27188386
C516138	dorsomorphin	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC2 mRNA	27188386
C516138	dorsomorphin	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC2 mRNA	27188386
C045651	epigallocatechin gallate	epigallocatechin gallate results in increased expression of TANC2 mRNA	22079256
C045651	epigallocatechin gallate	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TANC2 mRNA	22079256
D004958	Estradiol	[Estradiol co-treated with TGFB1 protein] results in increased expression of TANC2 mRNA	30165855
D004958	Estradiol	Estradiol results in increased expression of TANC2 mRNA	23019147
D004958	Estradiol	[bisphenol A co-treated with Estradiol] results in decreased expression of TANC2 mRNA	26496021
D000431	Ethanol	Ethanol affects the splicing of TANC2 mRNA	30319688
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of TANC2 mRNA	29097150
D017313	Fenretinide	Fenretinide results in increased expression of TANC2 mRNA	28973697
C007738	fluoranthene	[1-methylanthracene co-treated with fluoranthene] results in increased expression of TANC2 mRNA	28329830
D005742	Gasoline	[Gasoline results in increased chemical synthesis of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of TANC2 mRNA	29432896
C544151	jinfukang	[Cisplatin co-treated with jinfukang] results in decreased expression of TANC2 mRNA	27392435
D000077339	Leflunomide	Leflunomide results in increased expression of TANC2 mRNA	28988120
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of TANC2 mRNA	22235868
D008687	Metformin	Metformin results in decreased expression of TANC2 mRNA	31324951
D008701	Methapyrilene	Methapyrilene results in increased methylation of TANC2 intron	30157460
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of TANC2 mRNA	23103053
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of TANC2 mRNA	23179753; 28001369;
D052638	Particulate Matter	[Gasoline results in increased chemical synthesis of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of TANC2 mRNA	29432896
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether analog results in increased expression of TANC2 mRNA	19095052
D010662	Phenylmercuric Acetate	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC2 mRNA	27188386
D010662	Phenylmercuric Acetate	Phenylmercuric Acetate results in increased expression of TANC2 mRNA	26272509
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of TANC2 mRNA	19710929
D011084	Polycyclic Aromatic Hydrocarbons	[Gasoline results in increased chemical synthesis of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of TANC2 mRNA	29432896
C027373	potassium chromate(VI)	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TANC2 mRNA	22079256
C027373	potassium chromate(VI)	potassium chromate(VI) results in decreased expression of TANC2 mRNA	22079256
D011441	Propylthiouracil	Propylthiouracil results in increased expression of TANC2 mRNA	24780913
D012822	Silicon Dioxide	Silicon Dioxide results in decreased expression of TANC2 mRNA	25351596
D012834	Silver	Silver results in decreased expression of TANC2 mRNA	27131904
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of TANC2 mRNA	19770486
D019284	Thapsigargin	Thapsigargin results in increased expression of TANC2 protein	24648495
D013849	Thimerosal	Thimerosal results in decreased expression of TANC2 mRNA	27188386
C009495	titanium dioxide	titanium dioxide results in decreased expression of TANC2 mRNA	23557971
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in decreased expression of TANC2 mRNA	28065790
C012589	trichostatin A	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC2 mRNA	27188386
C012589	trichostatin A	trichostatin A results in increased expression of TANC2 mRNA	24935251; 26272509;
C016805	tris(1,3-dichloro-2-propyl)phosphate	tris(1,3-dichloro-2-propyl)phosphate results in increased expression of TANC2 mRNA	26179874
D014520	Urethane	Urethane results in increased expression of TANC2 mRNA	28818685
D014635	Valproic Acid	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC2 mRNA	27188386
D014635	Valproic Acid	Valproic Acid results in decreased expression of TANC2 mRNA	23527032
D014635	Valproic Acid	Valproic Acid results in increased expression of TANC2 mRNA	24383497; 24935251; 26272509;
D014635	Valproic Acid	Valproic Acid affects the splicing of TANC2 mRNA	29427782
D014635	Valproic Acid	Valproic Acid results in decreased expression of TANC2 mRNA	29427782
D014638	Vanadates	Vanadates results in increased expression of TANC2 mRNA	22714537
D000077337	Vorinostat	Vorinostat results in decreased expression of TANC2 mRNA	27188386

Functional annotations

Keywords

Keyword ID	Keyword Term
KW-0025	Alternative splicing
KW-0040	ANK repeat
KW-0965	Cell junction
KW-0966	Cell projection
KW-0225	Disease mutation
KW-0325	Glycoprotein
KW-0488	Methylation
KW-0597	Phosphoprotein
KW-0621	Polymorphism
KW-1185	Reference proteome
KW-0677	Repeat
KW-0770	Synapse
KW-0802	TPR repeat

Interpro

InterPro ID	InterPro Term
IPR002110	Ankyrin_rpt
IPR020683	Ankyrin_rpt-contain_dom
IPR036770	Ankyrin_rpt-contain_sf
IPR027417	P-loop_NTPase
IPR013026	TPR-contain_dom
IPR011990	TPR-like_helical_dom_sf
IPR019734	TPR_repeat

PROSITE

PROSITE ID	PROSITE Term
PS50297	ANK_REP_REGION
PS50088	ANK_REPEAT
PS50005	TPR
PS50293	TPR_REGION

Pfam

Pfam ID	Pfam Term
PF00023	Ank
PF12796	Ank_2
PF13181	TPR_8

Gene: TANC2

Basic information

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Identified variants/mutations related to cleft phenotype

Other genetic variants/mutations

Disease or phenotype associated information

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO:Biological Process

GO:Cellular Component

Reactome Pathway

Drugs and compounds information

Functional annotations

Keywords

Interpro

PROSITE

Pfam

Protein-protein interaction

Protein-miRNA interaction