| Tag | Content |
|---|---|
| Uniprot ID | Q9NR50; B2RBH8; D3DPZ2; Q5QP89; Q5QP90; Q8NDB5; Q8WV57; Q9H850; |
| Entrez ID | 8891 |
| Genbank protein ID | AAF91351.1; CAD38962.1; EAX07015.1; EAX07013.1; BAG37225.1; AAH18728.1; BAB14770.1; |
| Genbank nucleotide ID | NM_020365.4; NM_001166588.2; NM_001261418.1; |
| Ensembl protein ID | ENSP00000483996; ENSP00000361257; ENSP00000353575; |
| Ensembl nucleotide ID | ENSG00000070785 |
| Gene name | Translation initiation factor eIF-2B subunit gamma |
| Gene symbol | EIF2B3 |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 26449438 |
| Functional description | Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. |
| Sequence | MEFQAVVMAV GGGSRMTDLT SSIPKPLLPV GNKPLIWYPL NLLERVGFEE VIVVTTRDVQ 60 KALCAEFKMK MKPDIVCIPD DADMGTADSL RYIYPKLKTD VLVLSCDLIT DVALHEVVDL 120 FRAYDASLAM LMRKGQDSIE PVPGQKGKKK AVEQRDFIGV DSTGKRLLFM ANEADLDEEL 180 VIKGSILQKH PRIRFHTGLV DAHLYCLKKY IVDFLMENGS ITSIRSELIP YLVRKQFSSA 240 SSQQGQEEKE EDLKKKELKS LDIYSFIKEA NTLNLAPYDA CWNACRGDRW EDLSRSQVRC 300 YVHIMKEGLC SRVSTLGLYM EANRQVPKLL SALCPEEPPV HSSAQIVSKH LVGVDSLIGP 360 ETQIGEKSSI KRSVIGSSCL IKDRVTITNC LLMNSVTVEE GSNIQGSVIC NNAVIEKGAD 420 IKDCLIGSGQ RIEAKAKRVN EVIVGNDQLM EI 452 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.