ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PTPRU

Full Name:

protein tyrosine phosphatase, receptor type, U

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1p35.3-p35.1

Physical Location:

29435633-29525902 on NC_000001.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

AL049570

Dataset Information

Name:		12065639
Method:		Microarray
Tissue:		Frontal and motor cortices
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:		We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0005575	cellular_component	Cellular Component	ND
GO:0005887	integral to plasma membrane	Cellular Component	TAS (8700514)
GO:0004725	protein tyrosine phosphatase activity	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0016791	phosphoric monoester hydrolase activity	Molecular Function	IEA
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	Molecular Function	TAS (8700514)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0006464	protein modification process	Biological Process	TAS (8700514)
GO:0007155	cell adhesion	Biological Process	TAS (8700514)
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	Biological Process	TAS (8700514)
GO:0008150	biological_process	Biological Process	ND
GO:0006470	protein amino acid dephosphorylation	Biological Process	IEA