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Dataset Description
  • Dataset Name: 12065639
  • Species: Human
  • Method: Microarray
  • No. of Genes: 67
  • Tissue: Frontal and motor cortices
  • Phenotype: Alcohol dependence (AD)/Alcohol abuse/Alcoholism
  • Publication: Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
  • Dataset Summary: We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.

    Gene list of this dataset (67 genes)
    Page: 1 2 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    2670GFAPglial fibrillary acidic protein17q21AA059335 
    6813STXBP2syntaxin binding protein 219p13.3-p13.2AB002559 
    4744NEFHneurofilament, heavy polypeptide 200kDa22q12.2AB020652 
    1428CRYMcrystallin, mu16p13.11-p12.3AF001550 
    10844TUBGCP2tubulin, gamma complex associated protein 210q26.3AF042379 
    6199RPS6KB2ribosomal protein S6 kinase, 70kDa, polypeptide 211q13.1AF099739 
    1366CLDN7claudin 717p13AI151456 
    347APODapolipoprotein D3q26.2-qterAI188519 
    419ART3ADP-ribosyltransferase 34p15.1-p14|4p15.1-p14|4p15.1-pAI201027 
    7287TULP1tubby like protein 16p21.3AI380477 
    6622SNCAsynuclein, alpha (non A4 component of amyloid precursor)4q21AI634801 
    7080NKX2-1NK2 homeobox 114q13AI695053 
    7076TIMP1TIMP metallopeptidase inhibitor 1Xp11.3-p11.23AI831659 
    9322TRIP10thyroid hormone receptor interactor 1019p13.3AJ000414 
    6310ATXN1ataxin 16p23AL009031 
    4070TACSTD2tumor-associated calcium signal transducer 21p32-p31AL035411 
    10076PTPRUprotein tyrosine phosphatase, receptor type, U1p35.3-p35.1AL049570 
    7021TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta)6p12AL049693 
    1390CREMcAMP responsive element modulator10p11.21AL117336 
    1381CRABP1cellular retinoic acid binding protein 115q24AU132726 
    4336MOBPmyelin-associated oligodendrocyte basic protein3p22.1AV726735 
    1410CRYABcrystallin, alpha B11q22.3-q23.1AV733563 
    9527GOSR1golgi SNAP receptor complex member 117q11AW029303 
    2335FN1fibronectin 12q34AW385690 
    10972TMED10transmembrane emp24-like trafficking protein 10 (yeast)14q24.3AW504797 
    5354PLP1proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)Xq22AW950932 
    6383SDC2syndecan 28q22-q23AW951095 
    5573PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)17q23-q24AY007115 
    9230RAB11BRAB11B, member RAS oncogene family19p13.2BE266797 
    2824GPM6Bglycoprotein M6BXp22.2BE504823 
    5168ENPP2ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)8q24.1BE700679 
    9322TRIP10thyroid hormone receptor interactor 1019p13.3BE743785 
    10486CAP2CAP, adenylate cyclase-associated protein, 2 (yeast)6p22.3BF001174 
    805CALM2calmodulin 2 (phosphorylase kinase, delta)2p21BF671011 
    4501MT1Xmetallothionein 1X16q13BF676799 
    1230CCR1chemokine (C-C motif) receptor 13p21D10925 
    3156HMGCR3-hydroxy-3-methylglutaryl-Coenzyme A reductase5q13.3-q14H16650 
    4900NRGNneurogranin (protein kinase C substrate, RC3)11q24H46727 
    4852NPYneuropeptide Y7p15.1K01911 
    6252RTN1reticulon 114q23.1L10335 
    7857SCG2secretogranin II (chromogranin C)2q35-q36M25756 
    796CALCAcalcitonin-related polypeptide alpha11p15.2-p15.1M26095 
    7068THRBthyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)3p24.2M26747 
    595CCND1cyclin D111q13M73554 
    6662SOX9SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)17q24.3-q25.1NM_000346 
    1409CRYAAcrystallin, alpha A21q22.3NM_000394 
    776CACNA1Dcalcium channel, voltage-dependent, L type, alpha 1D subunit3p14.3NM_000720 
    786CACNG1calcium channel, voltage-dependent, gamma subunit 117q24NM_000727 
    Page: 1 2 list all