ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

APOD

Full Name:

apolipoprotein D

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

3q26.2-qter

Physical Location:

196776864-196792277 on NC_000003.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 11815 Fly: 33324 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

AI188519

Dataset Information

Name:		12065639
Method:		Microarray
Tissue:		Frontal and motor cortices
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:		We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.

Gene Information

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Information

Original ID1:

APOD

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001647.2	NP_001638.1	NC_000003.10 range: 196776864..196792277, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	TAS (3453108)
GO:0005576	extracellular region	Cellular Component	NAS (14718574)
GO:0008035	high-density lipoprotein binding	Molecular Function	NR
GO:0005215	transporter activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (7918467)
GO:0005501	retinoid binding	Molecular Function	IEA
GO:0005319	lipid transporter activity	Molecular Function	TAS (3453108)
GO:0008289	lipid binding	Molecular Function	IEA
GO:0006629	lipid metabolic process	Biological Process	TAS (3453108)
GO:0006810	transport	Biological Process	IEA