ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CRABP1

Full Name:

cellular retinoic acid binding protein 1

Alias:

CRABP|CRABP-I|CRABPI|RBP5

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

15q24

Physical Location:

76419749-76427621 on NC_000015.8

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 12903 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

AU132726

Dataset Information

Name:		12065639
Method:		Microarray
Tissue:		Frontal and motor cortices
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:		We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.

Gene Information

Original ID1:

CRABP1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_004378.1	NP_004369.1	NC_000015.8 range: 76419749..76427621

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005215	transporter activity	Molecular Function	IEA
GO:0008289	lipid binding	Molecular Function	IEA
GO:0016918	retinal binding	Molecular Function	IEA
GO:0019841	retinol binding	Molecular Function	IEA
GO:0006810	transport	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	TAS (1309505)
GO:0007275	multicellular organismal development	Biological Process	TAS (1309505)