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Gene Information
Gene ID:6383
Symbol:SDC2
Full Name:syndecan 2
Alias:HSPG|HSPG1|SYND2
Organism:Homo sapiens (Human)
Chromosome:8
Genetic Location:8q22-q23
Physical Location:97575057-97693212 on NC_000008.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AW951095
Dataset Information
Name:12065639
Method:Microarray
Tissue:Frontal and motor cortices
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.
Gene Information
Original ID1:BM971009
Fold Change:1.65
P Value:0.03
Tissue:Prefrontal cortex
Dataset Information
Name:15816859
Method:Microarray
Tissue:Prefrontal cortex and nucleus accumbens
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002998.3NP_002989.2NC_000008.9 range: 97575057..97693212
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005887integral to plasma membraneCellular ComponentNAS
GO:0016020membraneCellular ComponentIEA
GO:0003674molecular_functionMolecular FunctionND
GO:0008092cytoskeletal protein bindingMolecular FunctionIEA
GO:0008150biological_processBiological ProcessND
Other Database Cross Links
NCBI Entrez Gene:6383
HGNC:10659
Ensembl:ENSG00000169439
MIM:142460
HPRD:00803
HuGE Navigator:6383
dbSNP:SDC2
GeneCard:SDC2
AceView:SDC2