| Gene Information |
| Gene ID: | | 6383 |
| Symbol: | | SDC2 |
| Full Name: | | syndecan 2 |
| Alias: | | HSPG|HSPG1|SYND2 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 8 |
| Genetic Location: | | 8q22-q23 |
| Physical Location: | | 97575057-97693212 on NC_000008.9 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
|
| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | 12065639 | | Method: | | Microarray | | Tissue: | | Frontal and motor cortices | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed | | Summary: | | We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes. |
| | Gene Information | | Original ID1: | | BM971009 | | Fold Change: | | 1.65 | | P Value: | | 0.03 | | Tissue: | | Prefrontal cortex |
| | Dataset Information | | Name: | | 15816859 | | Method: | | Microarray | | Tissue: | | Prefrontal cortex and nucleus accumbens | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed | | Summary: | | Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test. |
|
|
| Gene Refseq Sequence Annotation |
|
| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005887 | integral to plasma membrane | Cellular Component | NAS | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0003674 | molecular_function | Molecular Function | ND | |
| GO:0008092 | cytoskeletal protein binding | Molecular Function | IEA | |
| GO:0008150 | biological_process | Biological Process | ND | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 6383 |
| HGNC: | | 10659 |
| Ensembl: | | ENSG00000169439 |
| MIM: | | 142460 |
| HPRD: | | 00803 |
| HuGE Navigator: | | 6383 |
| dbSNP: | | SDC2 |
| GeneCard: | | SDC2 |
| AceView: | | SDC2 |
