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Gene Information
Gene ID:595
Symbol:CCND1
Full Name:cyclin D1
Alias:BCL1|D11S287E|PRAD1|U21B31
Organism:Homo sapiens (Human)
Chromosome:11
Genetic Location:11q13
Physical Location:69165053-69178422 on NC_000011.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:M73554
Dataset Information
Name:12065639
Method:Microarray
Tissue:Frontal and motor cortices
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.
Gene Information
Original ID1:CCND1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_053056.2NP_444284.1NC_000011.8 range: 69165053..69178422
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0000307cyclin-dependent protein kinase holoenzyme complexCellular ComponentIDA (8114739|17420273)
GO:0005575cellular_componentCellular ComponentND
GO:0005622intracellularCellular ComponentIDA (11256614)
GO:0005654nucleoplasmCellular ComponentEXP (9190208|16782892)
GO:0005829cytosolCellular ComponentEXP (9106657)
GO:0005515protein bindingMolecular FunctionIPI (15232106|17254966|17274640|17334399)
GO:0019901protein kinase bindingMolecular FunctionIPI (8114739)
GO:0045737positive regulation of cyclin-dependent protein kinase activityBiological ProcessIDA (8114739)
GO:0007049cell cycleBiological ProcessIEA
GO:0000082G1/S transition of mitotic cell cycleBiological ProcessNAS
GO:0001934positive regulation of protein amino acid phosphorylationBiological ProcessIDA (8114739)
GO:0051301cell divisionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:595
HGNC:1582
Ensembl:ENSG00000110092
MIM:168461
HPRD:01346
HuGE Navigator:595
dbSNP:CCND1
GeneCard:CCND1
AceView:CCND1