ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

RPS6KB2

Full Name:

ribosomal protein S6 kinase, 70kDa, polypeptide 2

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q13.1

Physical Location:

66952510-66959454 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

AF099739

Dataset Information

Name:		12065639
Method:		Microarray
Tissue:		Frontal and motor cortices
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:		We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003952.2	NP_003943.2	NC_000011.8 range: 66952510..66959454

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005840	ribosome	Cellular Component	IEA
GO:0005654	nucleoplasm	Cellular Component	EXP (10490848)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	TAS (9878560)
GO:0004672	protein kinase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0006412	translation	Biological Process	TAS (9804755)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	TAS (9804755)