ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CRYAA

Full Name:

crystallin, alpha A

Alias:

CRYA1|HSPB4

Organism:

Homo sapiens (Human)

Chromosome:

21

Genetic Location:

21q22.3

Physical Location:

43462209-43465981 on NC_000021.7

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

NM_000394

Dataset Information

Name:		12065639
Method:		Microarray
Tissue:		Frontal and motor cortices
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:		We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000394.2	NP_000385.1	NC_000021.7 range: 43462209..43465981

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IDA (14752512)
GO:0005212	structural constituent of eye lens	Molecular Function	IEA
GO:0051082	unfolded protein binding	Molecular Function	NR
GO:0006457	protein folding	Biological Process	NAS (10217480)
GO:0006916	anti-apoptosis	Biological Process	IDA (14752512)
GO:0007601	visual perception	Biological Process	IMP (14512969)
GO:0032387	negative regulation of intracellular transport	Biological Process	IDA (14752512)
GO:0050896	response to stimulus	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000160202

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: