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Gene Information
Gene ID:1409
Symbol:CRYAA
Full Name:crystallin, alpha A
Alias:CRYA1|HSPB4
Organism:Homo sapiens (Human)
Chromosome:21
Genetic Location:21q22.3
Physical Location:43462209-43465981 on NC_000021.7
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:NM_000394
Dataset Information
Name:12065639
Method:Microarray
Tissue:Frontal and motor cortices
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000394.2NP_000385.1NC_000021.7 range: 43462209..43465981
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIDA (14752512)
GO:0005212structural constituent of eye lensMolecular FunctionIEA
GO:0051082unfolded protein bindingMolecular FunctionNR
GO:0006457protein foldingBiological ProcessNAS (10217480)
GO:0006916anti-apoptosisBiological ProcessIDA (14752512)
GO:0007601visual perceptionBiological ProcessIMP (14512969)
GO:0032387negative regulation of intracellular transportBiological ProcessIDA (14752512)
GO:0050896response to stimulusBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:1409
HGNC:2388
Ensembl:ENSG00000160202
MIM:123580
HPRD:00427
HuGE Navigator:1409
dbSNP:CRYAA
GeneCard:CRYAA
AceView:CRYAA