ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CAP2

Full Name:

CAP, adenylate cyclase-associated protein, 2 (yeast)

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

6p22.3

Physical Location:

17501714-17666001 on NC_000006.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

BF001174

Dataset Information

Name:		12065639
Method:		Microarray
Tissue:		Frontal and motor cortices
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:		We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_006366.2	NP_006357.1	NC_000006.10 range: 17501714..17666001

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0003779	actin binding	Molecular Function	IEA
GO:0005488	binding	Molecular Function	IEA
GO:0007010	cytoskeleton organization and biogenesis	Biological Process	IEA
GO:0007163	establishment and/or maintenance of cell polarity	Biological Process	TAS (7962207)
GO:0007165	signal transduction	Biological Process	TAS (7962207)
GO:0007190	activation of adenylate cyclase activity	Biological Process	TAS (7962207)