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Gene Information
Gene ID:1230
Symbol:CCR1
Full Name:chemokine (C-C motif) receptor 1
Alias:CD191|CKR-1|CMKBR1|HM145|MIP1aR|SCYAR1
Organism:Homo sapiens (Human)
Chromosome:3
Genetic Location:3p21
Physical Location:46218203-46224835 on NC_000003.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:D10925
Dataset Information
Name:12065639
Method:Microarray
Tissue:Frontal and motor cortices
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.
Gene Information
Original ID1:CCR1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001295.2NP_001286.1NC_000003.10 range: 46218203..46224835, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005887integral to plasma membraneCellular ComponentTAS (7505609)
GO:0005886plasma membraneCellular ComponentIDA (15474493)
GO:0005886plasma membraneCellular ComponentIMP (15001559)
GO:0016493C-C chemokine receptor activityMolecular FunctionIEA
GO:0001584rhodopsin-like receptor activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (15001559|15474493)
GO:0004872receptor activityMolecular FunctionIEA
GO:0007267cell-cell signalingBiological ProcessTAS (10734056)
GO:0007204elevation of cytosolic calcium ion concentrationBiological ProcessTAS (10734056)
GO:0007187G-protein signaling, coupled to cyclic nucleotide second messengerBiological ProcessTAS (7505609)
GO:0007155cell adhesionBiological ProcessTAS (10910894)
GO:0006955immune responseBiological ProcessTAS (10734056)
GO:0006954inflammatory responseBiological ProcessTAS (7683036)
GO:0006935chemotaxisBiological ProcessNAS (15474493)
GO:0019221cytokine and chemokine mediated signaling pathwayBiological ProcessNAS (15474493)
Other Database Cross Links
NCBI Entrez Gene:1230
HGNC:1602
Ensembl:ENSG00000163823
MIM:601159
HPRD:03101
HuGE Navigator:1230
dbSNP:CCR1
GeneCard:CCR1
AceView:CCR1