ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Plekha1

Full Name:

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

Alias:

AA960558|C920009D07Rik|TAPP1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 F3

Physical Location:

138009423-138056815 on NC_000073.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 59338 Symbol (Name): PLEKHA1 (pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1)

Ortholog Status:

The human GeneID 59338 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AA960558
Original ID2:		AI849556

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_133942.2	NP_598703.1	NC_000073.5 range: 138009423..138056815

Gene Ontology (GO) Annotation