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Dataset Description
  • Dataset Name: 15745951
  • Species: Mouse
  • Method: Microarray
  • No. of Genes: 277
  • Tissue: Nucleus accumbens, prefrontal cortex, and ventral tegmental area
  • Phenotype: Acute ethanol response
  • Publication: Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
  • Dataset Summary: The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

    Gene list of this dataset (277 genes)
    Page: 1 2 3 4 5 6 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    100732Mapre3microtubule-associated protein, RP/EB family, member 35 B1Mapre3AV091649
    101476Plekha1pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 17 F3AA960558AI849556
    102693Phldb1pleckstrin homology-like domain, family B, member 19 A5.2D330037A14RikAI854506
    103573Xpo1exportin 1, CRM1 homolog (yeast)11 A3.2Xpo1AW123788
    104001Rtn1reticulon 112 C3Rtn1M36777
    104069Sncbsynuclein, beta13 B1|13 35.0 cMSncbAI839708
    105445Dock9dedicator of cytokinesis 914 E5|14 67.0 cMD14Wsu89eAW125299
    107260Otub1OTU domain, ubiquitin aldehyde binding 119 AOtub1AI838318
    108655Foxp1forkhead box P16 E1Foxp1AA833293
    108655Foxp1forkhead box P16 E1Foxp1AW122985
    108911Rcc2regulator of chromosome condensation 24 D32610510H01RikAI846302
    109711Actn1actinin, alpha 112 C3|12 35.0 cMActn1AI195392
    110052DekDEK oncogene (DNA binding)13 B1|13 28.0 cMDekAA733594
    110058Syt17synaptotagmin XVII7 F2|7 56.0 cMBkAW046243
    110172Slc35b1solute carrier family 35, member B111 D|11 55.5 cMUgalt2AV372996
    110391Qdprquinoid dihydropteridine reductase5 B3|5 30.0 cMQdprAI845337
    110532Adarb1adenosine deaminase, RNA-specific, B110 41.4 cMAdarb1AV345565
    111662Iap11-1intracisternal A particles, Il3 linked11 29.0 cM---X04120
    11448Chrnecholinergic receptor, nicotinic, epsilon polypeptide11 B3|11 42.0 cMChrneAI326288
    11464Actc1actin, alpha, cardiac2 E4|2 64.0 cMActc1M15501
    114863Proscproline synthetase co-transcribed8 A31700024N20RikAW227620
    11516Adcyap1adenylate cyclase activating polypeptide 117 E5Adcyap1AB010149
    11564Adsladenylosuccinate lyase15 E1|15 46.0 cMAdslAA606587
    11566Adssadenylosuccinate synthetase, non muscle1 H4Adss2L24554
    11648Akp3alkaline phosphatase 3, intestine, not Mn requiring1 D|1 51.7 cMAkp3M61705
    11686Alox12barachidonate 12-lipoxygenase, 12R type11 B3|11 37.0 cMAlox12bX98475
    11686Alox12barachidonate 12-lipoxygenase, 12R type11 B3|11 37.0 cM---Y14334
    11733Ank1ankyrin 1, erythroid8 A2|8 9.5 cMAnk1U76758
    11735Ank3ankyrin 3, epithelial10 B5.3|10 38.0 cMAnk3L40632
    11785Apbb1amyloid beta (A4) precursor protein-binding, family B, member 17 E3|7 46.6 cMApbb1AI839886
    11853Rhocras homolog gene family, member C3 F2.2RhocX80638
    12064Bdnfbrain derived neurotrophic factor2 E3|2 62.0 cMBdnfX55573
    12122BidBH3 interacting domain death agonist6 F1|6 54.0 cMBidU75506
    12308Calb2calbindin 28 E1Calb2X73985
    12345Capzbcapping protein (actin filament) muscle Z-line, beta4 D3|4 66.8 cMCapzbAV107153
    12349Car2carbonic anhydrase 23 A1|3 10.5 cMCar2AV230631
    12387Ctnnb1catenin (cadherin associated protein), beta 19 F4|9 72.0 cMCatnbM90364
    12424Cckcholecystokinin9 F4|9 71.0 cMCckX59520
    12458Ccr6chemokine (C-C motif) receptor 617 A1Ccr6AJ222714
    12521Cd82CD82 antigen2 E1|2 49.6 cMKai1D14883
    12725Clcn3chloride channel 38 B3.1|8 32.2 cMClcn3AI849432
    12785Cnbpcellular nucleic acid binding protein6 D1-D2Cnbp1X63866
    12833Col6a1collagen, type VI, alpha 110 41.1 cMCol6a1X66405
    12843Col1a2collagen, type I, alpha 26 A1|6 0.68 cMCol1a2AW123632
    12864Cox6ccytochrome c oxidase, subunit VIc15 B3.3Cox6cAW060422
    12874Cpdcarboxypeptidase D11 B5|11 46.0 cMCpdD85391
    12876Cpecarboxypeptidase E8 B3.1|8 32.6 cMCpeX61232
    12891Cpne6copine VI14 C3Cpne6AB008893
    12896Cpt2carnitine palmitoyltransferase 24 C7|4 54.4 cMCpt2AV266650
    12933Crmp1collapsin response mediator protein 15 B3|5 21.0 cMCrmp1AB006714
    Page: 1 2 3 4 5 6 list all