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Gene Information
Gene ID:11735
Full Name:ankyrin 3, epithelial
Organism:Mus musculus (Mouse)
Genetic Location:10 B5.3|10 38.0 cM
Physical Location:68996455-69490183 on NC_000076.5
Gene Type:protein-coding
Human Ortholog:GeneID: 288    Symbol (Name): ANK3 (ankyrin 3, node of Ranvier (ankyrin G))
Ortholog Status:The human GeneID 288 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Ank3
Original ID2:L40632
Dataset Information
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_009670.4NP_033800.2NC_000076.5 range: 68996455..69490183
NM_146005.3NP_666117.2NC_000076.5 range: 68996455..69490183
NM_170687.3NP_733788.2NC_000076.5 range: 68996455..69490183
NM_170688.2NP_733789.1NC_000076.5 range: 68996455..69490183
NM_170689.2NP_733790.2NC_000076.5 range: 68996455..69490183
NM_170690.2NP_733791.2NC_000076.5 range: 68996455..69490183
NM_170728.2NP_733924.2NC_000076.5 range: 68996455..69490183
NM_170729.2NP_733925.2NC_000076.5 range: 68996455..69490183
NM_170730.2NP_733926.2NC_000076.5 range: 68996455..69490183
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0030424axonCellular ComponentIDA (15479642)
GO:0045202synapseCellular ComponentIDA (10995443)
GO:0005515protein bindingMolecular FunctionIPI (15823567)
GO:0005515protein bindingMolecular FunctionISO
GO:0007411axon guidanceBiological ProcessIMP (15479642)
GO:0050808synapse organization and biogenesisBiological ProcessIMP (15479642)
Other Database Cross Links
NCBI Entrez Gene:11735