ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Slc35b1

Full Name:

solute carrier family 35, member B1

Alias:

Ugalt2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 D|11 55.5 cM

Physical Location:

95246235-95252965 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10237 Symbol (Name): SLC35B1 (solute carrier family 35, member B1)

Ortholog Status:

The human GeneID 10237 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Ugalt2
Original ID2:		AV372996

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_016752.1	NP_058032.1	NC_000077.5 range: 95246235..95252965

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005351	sugar:hydrogen symporter activity	Molecular Function	IEA
GO:0006810	transport	Biological Process	IEA
GO:0008643	carbohydrate transport	Biological Process	IEA