ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Dek

Full Name:

DEK oncogene (DNA binding)

Alias:

1810019E15Rik|D13H6S231E

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

13 B1|13 28.0 cM

Physical Location:

47180153-47201478 on NC_000079.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7913 Symbol (Name): DEK (DEK oncogene (DNA binding))

Ortholog Status:

The human GeneID 7913 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Dek
Original ID2:		AA733594

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_025900.1	NP_080176.1	NC_000079.5 range: 47180153..47201478, complement

Gene Ontology (GO) Annotation