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Dataset Description
  • Dataset Name: 15745951
  • Species: Mouse
  • Method: Microarray
  • No. of Genes: 277
  • Tissue: Nucleus accumbens, prefrontal cortex, and ventral tegmental area
  • Phenotype: Acute ethanol response
  • Publication: Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
  • Dataset Summary: The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

    Gene list of this dataset (277 genes)
    Page: 1 2 3 4 5 6 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    19243Ptp4a1protein tyrosine phosphatase 4a11 BPtp4a1U84411
    19346Rab6RAB6, member RAS oncogene family7 C4Rab6AI851048
    19349Rab7RAB7, member RAS oncogene family6 D1|6 38.5 cMRab7Y13361
    19359Rad23bRAD23b homolog (S. cerevisiae)4 B3Rad23bX92411
    19415Rasal1RAS protein activator like 1 (GAP1 like)5 FRasal1AF086714
    19662Rbp4retinol binding protein 4, plasma19 D1|19 38.0 cMRbp4U63146
    19946Rpl30ribosomal protein L3015 B3.1|15 14.7 cMRpl30K02928
    20016Rpo1-1RNA polymerase 1-117 CRpo1-1U11248
    20199S100a5S100 calcium binding protein A53 F1-F2|3 43.6 cMS100a5AF087469
    20257Stmn2stathmin-like 23 A1|3 6.6 cMStmn2AI840972
    20359Sema6bsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B17 DSema6bAF036585
    20370Sez6seizure related gene 611 B5|11 44.83 cMSez6D29763
    20378Frzbfrizzled-related protein2 C3|2 49.75 cMFrzbU68058
    20393Sgk1serum/glucocorticoid regulated kinase 110 A3SgkAW046181
    20451St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 318 E1Siat8cX80502
    20568Slpisecretory leukocyte peptidase inhibitor-SlpiAV087239
    20606Sstr2somatostatin receptor 211 E2|11 69.0 cMSstr2AF008914
    20656Sod2superoxide dismutase 2, mitochondrial17 A1|17 7.6 cMSod2L35528
    20665Sox10SRY-box containing gene 1015 E1|15 46.6 cMSox10AF047389
    20665Sox10SRY-box containing gene 1015 E1|15 46.6 cMSox10AW125812
    20716Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N12 F1Serpina3nM64086
    20729Spin1spindlin 113 A5|13 31.0 cMSpinAW124681
    20743Spnb3spectrin beta 319 A|19 0.0 cMSpnb3AF026489
    20756Sprr2bsmall proline-rich protein 2B3 F1|3 45.2 cMSprr2bAJ005560
    20907Stx1asyntaxin 1A (brain)5 G2Stx1aD45208
    21333Tac1tachykinin 16 A1|6 5.0 cMTac1D17584
    21334Tac2tachykinin 210 D3Tac2D14423
    21372Tbl1xtransducin (beta)-like 1 X-linkedX B-C|X 30.9 cMTbl1xAV230631
    21375Tbr1T-box brain gene 12 C1.3|2 32.0 cMTbr1U49251
    214290Zcchc6zinc finger, CCHC domain containing 613 B2Zcchc6AI851441
    216134Pdxkpyridoxal (pyridoxine, vitamin B6) kinase10 C1|10 42.1 cMPdxkAI450876
    216157ORF61open reading frame 6110 C1ORF61AI837492
    21821Ift88intraflagellar transport 88 homolog (Chlamydomonas)14 C3|14 21.0 cMTg737RpwAI451701
    21823Thtyrosine hydroxylase7 F5|7 69.2 cMThM69200
    21847Klf10Kruppel-like factor 1015 B3.1Tieg1AF064088
    21924Tnnc1troponin C, cardiac/slow skeletal14 B|14 10.0 cMTnccM29793
    21942Tnfrsf9tumor necrosis factor receptor superfamily, member 94 E2|4 75.5 cMTnfrsf9U02567
    21946Pglyrp1peptidoglycan recognition protein 17 A3Pglyrp1AF076482
    21955Tnnt1troponin T1, skeletal, slow7 A1|7 9.0 cMTnnt1AJ131711
    21955Tnnt1troponin T1, skeletal, slow7 A1|7 9.0 cMTnnt1AV213431
    22139Ttrtransthyretin18 A2|18 7.0 cMTtrAW123115
    22323Vaspvasodilator-stimulated phosphoprotein7 A3VaspAI463490
    223666D15Wsu169eDNA segment, Chr 15, Wayne State University 169, expressed15 D3|15 44.7 cMD15Wsu169eAI835989
    223754Tbc1d22aTBC1 domain family, member 22a15 E2|15 49.3 cMD15Ertd781eAI849705
    225288Fhod3formin homology 2 domain containing 318 A2FHOS2AA795285
    226778Mark1MAP/microtubule affinity-regulating kinase 11 H5Mark1AA080253
    227298BC038286cDNA sequence BC0382861 C3BC038286AW050156
    227937Pkp4plakophilin 42 C3Pkp4AI837021
    232223Txnrd3thioredoxin reductase 36 D1Txnrd3AV299386
    232798Leng8leukocyte receptor cluster (LRC) member 87 A1Leng8AI851703
    Page: 1 2 3 4 5 6 list all