ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Zcchc6

Full Name:

zinc finger, CCHC domain containing 6

Alias:

6030448M23Rik|AA420405|MGC38585

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

13 B2

Physical Location:

59873239-59924461 on NC_000079.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 79670 Symbol (Name): ZCCHC6 (zinc finger, CCHC domain containing 6)

Ortholog Status:

The human GeneID 79670 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Zcchc6
Original ID2:		AI851441

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_153538.2	NP_705766.2	NC_000079.5 range: 59873239..59924461, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0003676	nucleic acid binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0016779	nucleotidyltransferase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA