ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Vasp

Full Name:

vasodilator-stimulated phosphoprotein

Alias:

AA107290

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 A3

Physical Location:

19843065-19858495 on NC_000073.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7408 Symbol (Name): VASP (vasodilator-stimulated phosphoprotein)

Ortholog Status:

The human GeneID 7408 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Vasp
Original ID2:		AI463490

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009499.2	NP_033525.2	NC_000073.5 range: 19843065..19858495, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0042995	cell projection	Cellular Component	IEA
GO:0030027	lamellipodium	Cellular Component	IDA (15148305)
GO:0016020	membrane	Cellular Component	IEA
GO:0030175	filopodium	Cellular Component	IDA (15148305\|15294161)
GO:0005925	focal adhesion	Cellular Component	IDA (15148305)
GO:0005856	cytoskeleton	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0030054	cell junction	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI (16319076)
GO:0003779	actin binding	Molecular Function	IEA
GO:0030036	actin cytoskeleton organization and biogenesis	Biological Process	IGI (15371503)
GO:0007411	axon guidance	Biological Process	IGI (15371503)
GO:0001843	neural tube closure	Biological Process	IGI (15371503)