ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Fhod3

Full Name:

formin homology 2 domain containing 3

Alias:

A930009H06Rik|FHOS2|KIAA1695|mKIAA1695

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

18 A2

Physical Location:

24867945-25292001 on NC_000084.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 80206 Symbol (Name): FHOD3 (formin homology 2 domain containing 3)

Ortholog Status:

The human GeneID 80206 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		FHOS2
Original ID2:		AA795285

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_175276.3	NP_780485.2	NC_000084.5 range: 24867945..25292001

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005856	cytoskeleton	Cellular Component	IEA
GO:0003779	actin binding	Molecular Function	IEA
GO:0016043	cellular component organization and biogenesis	Biological Process	IEA
GO:0030036	actin cytoskeleton organization and biogenesis	Biological Process	IEA