Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:21334
Full Name:tachykinin 2
Organism:Mus musculus (Mouse)
Genetic Location:10 D3
Physical Location:127161533-127168822 on NC_000076.5
Gene Type:protein-coding
Human Ortholog:GeneID: 6866    Symbol (Name): TAC3 (tachykinin 3 (neuromedin K, neurokinin beta))
Ortholog Status:The human GeneID 6866 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Tac2
Original ID2:D14423
Dataset Information
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_009312.2NP_033338.2NC_000076.5 range: 127161533..127168822
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005615extracellular spaceCellular ComponentRCA (12466851)
GO:0007217tachykinin signaling pathwayBiological ProcessIEA
GO:0007218neuropeptide signaling pathwayBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:21334