ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ttr

Full Name:

transthyretin

Alias:

AA408768|AI787086|D17860|MGC107649|prealbumin

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

18 A2|18 7.0 cM

Physical Location:

20823913-20832819 on NC_000084.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7276 Symbol (Name): TTR (transthyretin (prealbumin, amyloidosis type I))

Ortholog Status:

The human GeneID 7276 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Ttr
Original ID2:		AW123115

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013697.4	NP_038725.1	NC_000084.5 range: 20823913..20832819

Gene Ontology (GO) Annotation