ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Pglyrp1

Full Name:

peptidoglycan recognition protein 1

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 A3

Physical Location:

19470038-19475786 on NC_000073.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 8993 Symbol (Name): PGLYRP1 (peptidoglycan recognition protein 1)

Ortholog Status:

The human GeneID 8993 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Pglyrp1
Original ID2:		AF076482

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009402.2	NP_033428.1	NC_000073.5 range: 19470038..19475786

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005125	cytokine activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0016019	peptidoglycan receptor activity	Molecular Function	ISS (11461926)
GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	Molecular Function	IEA
GO:0009253	peptidoglycan catabolic process	Biological Process	IEA
GO:0006955	immune response	Biological Process	IEA
GO:0006915	apoptosis	Biological Process	IEA
GO:0042742	defense response to bacterium	Biological Process	IEA