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Gene Information
Gene ID:19346
Symbol:Rab6
Full Name:RAB6, member RAS oncogene family
Alias:2610028L11Rik|AA419671
Organism:Mus musculus (Mouse)
Chromosome:7
Genetic Location:7 C4
Physical Location:107756276-107790148 on NC_000073.5
Gene Type:protein-coding
Human Ortholog:GeneID: 5870    Symbol (Name): RAB6A (RAB6A, member RAS oncogene family)
Ortholog Status:The human GeneID 5870 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rab6
Original ID2:AI851048
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_024287.3NP_077249.1NC_000073.5 range: 107756276..107790148
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005794Golgi apparatusCellular ComponentIDA (11042173)
GO:0005794Golgi apparatusCellular ComponentISS (11121396|15229288)
GO:0016020membraneCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (7631419)
GO:0005525GTP bindingMolecular FunctionIEA
GO:0016192vesicle-mediated transportBiological ProcessIEA
GO:0015031protein transportBiological ProcessIEA
GO:0007264small GTPase mediated signal transductionBiological ProcessIEA
GO:0006886intracellular protein transportBiological ProcessTAS (11042173)
GO:0006810transportBiological ProcessIEA
GO:0018125peptidyl-cysteine methylationBiological ProcessISS (11121396)
Other Database Cross Links
NCBI Entrez Gene:19346
MGI:
Ensembl:ENSMUSG00000030704
dbSNP:Rab6
AceView:Rab6