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Dataset Description
  • Dataset Name: 15745951
  • Species: Mouse
  • Method: Microarray
  • No. of Genes: 277
  • Tissue: Nucleus accumbens, prefrontal cortex, and ventral tegmental area
  • Phenotype: Acute ethanol response
  • Publication: Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
  • Dataset Summary: The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

    Gene list of this dataset (277 genes)
    Page: 1 2 3 4 5 6 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    13056Cyb561cytochrome b-56111 E1|11 65.0 cMCyb561U16297
    13144Dapk3death-associated kinase 310 C1|10 43.0 cMDapk3AB007143
    13170DbpD site albumin promoter binding protein7 B4|7 23.0 cMDbpAW047343
    13197Gadd45agrowth arrest and DNA-damage-inducible 45 alpha6 C1Gadd45aU00937
    13207Ddx5DEAD (Asp-Glu-Ala-Asp) box polypeptide 511 E2|11 63.0 cMDdx5X65627
    13390Dlx1distal-less homeobox 12 C2|2 44.0 cMDlx1U51000
    13643Efnb3ephrin B311 B3|11 40.0 cMEfnb3AW121468
    13653Egr1early growth response 118 C/D|18 16.0 cMEgr1M28845
    13664Eif1aeukaryotic translation initiation factor 1A18 CEif1aAF026481
    13865Nr2f1nuclear receptor subfamily 2, group F, member 113 C1|13 45.0 cMNr2f1X74134
    14017Evi2aecotropic viral integration site 2a11 B5|11 46.13 cMEvi2aM34896
    14077Fabp3fatty acid binding protein 3, muscle and heart4 D2.2|4 61.0 cMFabp3X14961
    14086Fscn1fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)5 G2|5 86.0 cMFscn1L33726
    14208Ppm1gprotein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform5 B1|5 19.0 cMPpm1gU42383
    14219Ctgfconnective tissue growth factor10 A3-B1|10 17.0 cMCtgfM70642
    14229Fkbp5FK506 binding protein 517 A3.3|17 13.0 cMFkbp5U16959
    14265Fmr1fragile X mental retardation syndrome 1 homologX A7.1|X 24.5 cMFmr1L23971
    14282FosbFBJ osteosarcoma oncogene B7 A2-B1|7 5.0 cMFosbX14897
    14294Fpr3formyl peptide receptor 317 A3.2Fprl1AU045946
    14294Fpr3formyl peptide receptor 317 A3.2---U78299
    14387Gaaglucosidase, alpha, acid11 D-E|11 74.0 cMGaaU49351
    14400Gabrb1gamma-aminobutyric acid (GABA-A) receptor, subunit beta 15 C3.2|5 40.0 cMGabrb1U14418
    14406Gabrg2gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 211 A5|11 19.0 cMGabrg2M62374
    14472Gbx2gastrulation brain homeobox 21 C5-E1|1 65.0 cMGbx2Z48800
    14580Gfapglial fibrillary acidic protein11 D|11 62.0 cMGfapX02801
    14677Gnai1guanine nucleotide binding protein (G protein), alpha inhibiting 15 A3|5 2.0 cMGnai1AI153412
    14678Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 29 F1|9 59.0 cMGnai2M13963
    14681Gnao1guanine nucleotide binding protein, alpha O8 C5|8 45.0 cMGnaoAA259683
    14697Gnb5guanine nucleotide binding protein (G protein), beta 59 D|9 41.0 cMGnb5L34290
    14739S1pr2sphingosine-1-phosphate receptor 29 A3|9 6.0 cMEdg5AF108020
    14745Lpar1lysophosphatidic acid receptor 14 B3|4 16.0 cMEdg2U13370
    14765Gpr50G-protein-coupled receptor 50X A7.2|X 26.0 cMGpr50AF065145
    14784Grb2growth factor receptor bound protein 211 E2|11 75.0 cMGrb2U07617
    14803Grid1glutamate receptor, ionotropic, delta 114 B|14 13.5 cMGrid1D10171
    14827Pdia3protein disulfide isomerase associated 32 E5|2 69.0 cMGrp58M73329
    14828Hspa5heat shock protein 52 B|2 22.5 cMHspa5AJ002387
    14854Gssglutathione synthetase2 H1GssU35456
    15114Hap1huntingtin-associated protein 111 D|11 60.0 cMHap1AJ002272
    15115Harshistidyl-tRNA synthetase18 B2HarsU39473
    15122Hba-a1hemoglobin alpha, adult chain 111 A4|11 16.0 cMHba-a1AV003378
    15129Hbb-b1hemoglobin, beta adult major chain7 E3|7 50.0 cMHbb-b1J00413
    15166Hcn2hyperpolarization-activated, cyclic nucleotide-gated K+ 210 C1Hcn2AJ225122
    15239HgsHGF-regulated tyrosine kinase substrate11 E2|11 75.0 cMHgsD50050
    15354Hmgb3high mobility group box 3X A1Hmgb3AW060179
    15370Nr4a1nuclear receptor subfamily 4, group A, member 115 FNr4a1X16995
    15481Hspa8heat shock protein 89 A5.1|9 24.0 cMHspa8X54401
    15502Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 14 A5Dnaja1AF055664
    15531Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 118 D2Ndst1AI844370
    15572Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)4 C7|4 49.5 cMElavl4D31953
    16453Jak3Janus kinase 38 B3.3|8 33.0 cMJak3AI854103
    Page: 1 2 3 4 5 6 list all