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Gene Information
Gene ID:13664
Symbol:Eif1a
Full Name:eukaryotic translation initiation factor 1A
Alias:C76390|Ef1a|Eftu|Eif4c|eIF-1A
Organism:Mus musculus (Mouse)
Chromosome:18
Genetic Location:18 C
Physical Location:46757357-46769861 on NC_000084.5
Gene Type:protein-coding
Human Ortholog:GeneID: 1964    Symbol (Name): EIF1AX (eukaryotic translation initiation factor 1A, X-linked)
Ortholog Status:The human GeneID 1964 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Eif1a
Original ID2:AF026481
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_010120.5NP_034250.3NC_000084.5 range: 46757357..46769861
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentRCA (16141072)
GO:0003676nucleic acid bindingMolecular FunctionRCA (16141072)
GO:0003723RNA bindingMolecular FunctionRCA (16141072)
GO:0003743translation initiation factor activityMolecular FunctionRCA (16141072)
GO:0005215transporter activityMolecular FunctionRCA (16141072)
GO:0006412translationBiological ProcessIEA
GO:0006413translational initiationBiological ProcessRCA (16141072)
GO:0006810transportBiological ProcessRCA (16141072)
Other Database Cross Links
NCBI Entrez Gene:13664
MGI:
Ensembl:ENSMUSG00000057561
dbSNP:Eif1a
AceView:Eif1a