ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Fabp3

Full Name:

fatty acid binding protein 3, muscle and heart

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 D2.2|4 61.0 cM

Physical Location:

129986021-129992706 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2170 Symbol (Name): FABP3 (fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor))

Ortholog Status:

The human GeneID 2170 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Fabp3
Original ID2:		X14961

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010174.1	NP_034304.1	NC_000070.5 range: 129986021..129992706

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005215	transporter activity	Molecular Function	IEA
GO:0005488	binding	Molecular Function	IEA
GO:0008289	lipid binding	Molecular Function	IEA
GO:0006656	phosphatidylcholine biosynthetic process	Biological Process	IGI (15164767)
GO:0006810	transport	Biological Process	IEA