ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Evi2a

Full Name:

ecotropic viral integration site 2a

Alias:

AW491894|Evi-2|Evi2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B5|11 46.13 cM

Physical Location:

79340061-79344110 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2123 Symbol (Name): EVI2A (ecotropic viral integration site 2A)

Ortholog Status:

The human GeneID 2123 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Evi2a
Original ID2:		M34896

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	RCA (16141072)
GO:0004888	transmembrane receptor activity	Molecular Function	RCA (16141072)
GO:0008283	cell proliferation	Biological Process	RCA (16141072)
GO:0009987	cellular process	Biological Process	RCA (16141072)