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Dataset Description
  • Dataset Name: 15745951
  • Species: Mouse
  • Method: Microarray
  • No. of Genes: 277
  • Tissue: Nucleus accumbens, prefrontal cortex, and ventral tegmental area
  • Phenotype: Acute ethanol response
  • Publication: Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
  • Dataset Summary: The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

    Gene list of this dataset (277 genes)
    Page: 1 2 3 4 5 6 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    66493Mrpl51mitochondrial ribosomal protein L516 F2Mrpl51AI844598
    66597Trim13tripartite motif-containing 1314 D1Trim13AI592541
    66676Tmed7transmembrane emp24 protein transport domain containing 718 C3930401E15RikAI846109
    66849Ppp1r2protein phosphatase 1, regulatory (inhibitor) subunit 216 B2Ppp1r2AW049584
    66881Pcyox1prenylcysteine oxidase 16 D1Pcyox1AI850953
    67003Uqcrc2ubiquinol cytochrome c reductase core protein 27 F2Uqcrc2AI842835
    67203Nde1nuclear distribution gene E homolog 1 (A nidulans)16 A1Nde1AW120739
    67247Mosc2MOCO sulphurase C-terminal domain containing 21 H42810484M10RikAW124268
    67399Pdlim7PDZ and LIM domain 713 B2Pdlim7AW125223
    67603Dusp6dual specificity phosphatase 610 C3Dusp6AI845584
    67874Rprmreprimo, TP53 dependent G2 arrest mediator candidate2 C12410012A13RikAV354117
    67991Btbd14aBTB (POZ) domain containing 14A2 A3Btbd14aAW122114
    68097Dynll2dynein light chain LC8-type 211 C6720463E02RikAI836322
    68147Nola1nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)3 G3Nola1AF022465
    68539Tmem109transmembrane protein 10919 A1110006I15RikAI853127
    68728Trp53inp2transformation related protein 53 inducible nuclear protein 22 H11110029F20RikAW125508
    68743Anlnanillin, actin binding protein (scraps homolog, Drosophila)9 A4AnlnAW123269
    68842Tulp4tubby like protein 417 A1|17 3.2 cMTulp4AI848591
    688611190002N15RikRIKEN cDNA 1190002N15 gene9 E3.31190002N15RikAW125453
    689181190005I06RikRIKEN cDNA 1190005I06 gene8 E11190005I06RikAI844196
    69077Psmd11proteasome (prosome, macropain) 26S subunit, non-ATPase, 1111 B5Psmd11AA710643
    69581Rhouras homolog gene family, member U8 E2RhouAV246963
    69581Rhouras homolog gene family, member U8 E2RhouAW121294
    71207Nudt4nudix (nucleoside diphosphate linked moiety X)-type motif 4-Nudt4AI843747
    71207Nudt4nudix (nucleoside diphosphate linked moiety X)-type motif 4-Nudt4AI851198
    71745Cul2cullin 218 A1Cul2AI854281
    71853Pdia6protein disulfide isomerase associated 612 A1.1Txndc7AI842377
    71853Pdia6protein disulfide isomerase associated 612 A1.1Txndc7AW045202
    72124Seh1lSEH1-like (S. cerevisiae18 E12610007A16RikAW124855
    737371110008P14RikRIKEN cDNA 1110008P14 gene2 B1110008P14RikAI839839
    745042410018C17RikRIKEN cDNA 2410018C17 gene5 B25430419M09RikAI838550
    74747Ddit4DNA-damage-inducible transcript 410 B3Ddit4AI849939
    765661500005K14RikRIKEN cDNA 1500005K14 gene11 B41500005K14RikAW047875
    76582Ipo11importin 1113 D2.1Ipo11AW124742
    769582210418O10RikRIKEN cDNA 2210418O10 gene2 H42210418O10RikAV055186
    76987Hdhd2haloacid dehalogenase-like hydrolase domain containing 218 E33110052N05RikAI853675
    77106Tmem181transmembrane protein 18117 A15930418K15RikAW125272
    81898Sf3b1splicing factor 3b, subunit 11 C1.2|1 28.9 cMSf3b1AI844532
    83797Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 115 F1|15 56.8 cMSmarcd1M25773
    93706Pcdhgc3protocadherin gamma subfamily C, 318 B3Pcdhgc3AI854522
    94049Ms10hminisatellite 10h detected by probe MMS10-Ms10hAC002397
    94214Spock2sparc/osteonectin, cwcv and kazal-like domains proteoglycan 210 B3Spock2AI844853
    99480Dnttip2deoxynucleotidyltransferase, terminal, interacting protein 23 G14930588M11RikAA407120
        ---AA145282
        ---AF031164
        ---AI853573
        ---AV328137
        AW060714AI845028
        ---AW214439
        ---C77009
    Page: 1 2 3 4 5 6 list all