ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Rprm

Full Name:

reprimo, TP53 dependent G2 arrest mediator candidate

Alias:

2410012A13Rik|Reprimo

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 C1

Physical Location:

53936503-53937962 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 56475 Symbol (Name): RPRM (reprimo, TP53 dependent G2 arrest mediator candidate)

Ortholog Status:

The human GeneID 56475 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		2410012A13Rik
Original ID2:		AV354117

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_023396.4	NP_075885.1	NC_000068.6 range: 53936503..53937962, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IDA (10930422)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0003674	molecular_function	Molecular Function	ND
GO:0007050	cell cycle arrest	Biological Process	IDA (10930422)
GO:0007346	regulation of mitotic cell cycle	Biological Process	IDA (10930422)