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Gene Information
Gene ID:68539
Symbol:Tmem109
Full Name:transmembrane protein 109
Alias:1110006I15Rik|AA958958|C77652
Organism:Mus musculus (Mouse)
Chromosome:19
Genetic Location:19 A
Physical Location:10945149-10956232 on NC_000085.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 79073    Symbol (Name): TMEM109 (transmembrane protein 109)
Ortholog Status:The human GeneID 79073 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:1110006I15Rik
Original ID2:AI853127
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_134142.1NP_598903.1NC_000085.5 range: 10945149..10956232, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005615extracellular spaceCellular ComponentRCA (12466851)
GO:0005634nucleusCellular ComponentIEA
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentRCA (12466851)
GO:0016529sarcoplasmic reticulumCellular ComponentIEA
Other Database Cross Links
NCBI Entrez Gene:68539
MGI:
Ensembl:ENSMUSG00000034659
dbSNP:Tmem109
AceView:Tmem109