Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:67003
Symbol:Uqcrc2
Full Name:ubiquinol cytochrome c reductase core protein 2
Alias:1500004O06Rik
Organism:Mus musculus (Mouse)
Chromosome:7
Genetic Location:7 F2
Physical Location:127778702-127803036 on NC_000073.5
Gene Type:protein-coding
Human Ortholog:GeneID: 7385    Symbol (Name): UQCRC2 (ubiquinol-cytochrome c reductase core protein II)
Ortholog Status:The human GeneID 7385 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Uqcrc2
Original ID2:AI842835
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_025899.2NP_080175.1NC_000073.5 range: 127778702..127803036
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0005739mitochondrionCellular ComponentIDA (16103131|16120479)
GO:0005743mitochondrial inner membraneCellular ComponentIDA (12865426)
GO:0005746mitochondrial respiratory chainCellular ComponentIEA
GO:0003824catalytic activityMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0004222metalloendopeptidase activityMolecular FunctionIEA
GO:0006810transportBiological ProcessIEA
GO:0006508proteolysisBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:67003
MGI:
Ensembl:ENSMUSG00000030884
dbSNP:Uqcrc2
AceView:Uqcrc2