ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mrpl51

Full Name:

mitochondrial ribosomal protein L51

Alias:

2610511M02Rik|CDA09|HSPC241|Mrp64

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

6 F2

Physical Location:

125142217-125144409 on NC_000072.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 51258 Symbol (Name): MRPL51 (mitochondrial ribosomal protein L51)

Ortholog Status:

The human GeneID 51258 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Mrpl51
Original ID2:		AI844598

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_025595.3	NP_079871.1	NC_000072.5 range: 125142217..125144409

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005739	mitochondrion	Cellular Component	IEA
GO:0005761	mitochondrial ribosome	Cellular Component	IDA (11402041)
GO:0005840	ribosome	Cellular Component	IEA
GO:0030529	ribonucleoprotein complex	Cellular Component	IEA
GO:0003735	structural constituent of ribosome	Molecular Function	IDA (11402041)
GO:0006412	translation	Biological Process	IDA (11402041)