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Gene Information
Gene ID:66493
Full Name:mitochondrial ribosomal protein L51
Organism:Mus musculus (Mouse)
Genetic Location:6 F2
Physical Location:125142217-125144409 on NC_000072.5
Gene Type:protein-coding
Human Ortholog:GeneID: 51258    Symbol (Name): MRPL51 (mitochondrial ribosomal protein L51)
Ortholog Status:The human GeneID 51258 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Mrpl51
Original ID2:AI844598
Dataset Information
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_025595.3NP_079871.1NC_000072.5 range: 125142217..125144409
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005615extracellular spaceCellular ComponentRCA (12466851)
GO:0005739mitochondrionCellular ComponentIEA
GO:0005761mitochondrial ribosomeCellular ComponentIDA (11402041)
GO:0005840ribosomeCellular ComponentIEA
GO:0030529ribonucleoprotein complexCellular ComponentIEA
GO:0003735structural constituent of ribosomeMolecular FunctionIDA (11402041)
GO:0006412translationBiological ProcessIDA (11402041)
Other Database Cross Links
NCBI Entrez Gene:66493