ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MRPL51

Full Name:

mitochondrial ribosomal protein L51

Alias:

CDA09|HSPC241|MRP64|bMRP64

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

12p13.3-p13.1

Physical Location:

6471576-6472717 on NC_000012.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 66493 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Linkage Dataset

Marker

LOD

P value

Location (bp)

D12S99

5434815

Region:		3434815-7434815
Phenotype:		Alcoholism phenotype along with age, gender, and P300 or constraint
Name:		15211641
Method:		Linkage
Publication:		Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:		A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_016497.3	NP_057581.2	NC_000012.10 range: 6471576..6472717, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IEA
GO:0005762	mitochondrial large ribosomal subunit	Cellular Component	ISS
GO:0005840	ribosome	Cellular Component	IEA
GO:0003735	structural constituent of ribosome	Molecular Function	ISS
GO:0006412	translation	Biological Process	ISS