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Gene Information
Gene ID:71207
Symbol:Nudt4
Full Name:nudix (nucleoside diphosphate linked moiety X)-type motif 4
Alias:4933436C10Rik|DIPP2|DIPP2alpha|DIPP2beta|HDCMB47P
Organism:Mus musculus (Mouse)
Chromosome:10
Physical Location:95009922-95026779 on NC_000076.5, complement
Gene Type:protein-coding
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Nudt4
Original ID2:AI843747
Gene Information
Original ID1:Nudt4
Original ID2:AI851198
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_027722.4NP_081998.3NC_000076.5 range: 95009922..95026779, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0000287magnesium ion bindingMolecular FunctionIEA
GO:0016787hydrolase activityMolecular FunctionIEA
GO:0030145manganese ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:71207
MGI:
Ensembl:ENSMUSG00000020029
dbSNP:Nudt4
AceView:Nudt4