ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tulp4

Full Name:

tubby like protein 4

Alias:

1110057P05Rik|2210038L17Rik|Tusp

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

17 A1|17 3.2 cM

Physical Location:

6106887-6124138 on NC_000083.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 56995 Symbol (Name): TULP4 (tubby like protein 4)

Ortholog Status:

The human GeneID 56995 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Tulp4
Original ID2:		AI848591

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	ISS (11595174)
GO:0003674	molecular_function	Molecular Function	ND
GO:0006512	ubiquitin cycle	Biological Process	IEA
GO:0007242	intracellular signaling cascade	Biological Process	IEA
GO:0008150	biological_process	Biological Process	ND