ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Trp53inp2

Full Name:

transformation related protein 53 inducible nuclear protein 2

Alias:

1110029F20Rik|Tp53inp2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 H1

Physical Location:

155207591-155215582 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 58476 Symbol (Name): TP53INP2 (tumor protein p53 inducible nuclear protein 2)

Ortholog Status:

The human GeneID 58476 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		1110029F20Rik
Original ID2:		AW125508

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_178111.3	NP_835212.1	NC_000068.6 range: 155207591..155215582

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA