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Gene Information
Gene ID:67203
Symbol:Nde1
Full Name:nuclear distribution gene E homolog 1 (A nidulans)
Alias:2810027M15Rik|AU042936|AW822251|Nude|mNudE
Organism:Mus musculus (Mouse)
Chromosome:16
Genetic Location:16 A1
Physical Location:14169567-14192658 on NC_000082.5
Gene Type:protein-coding
Human Ortholog:GeneID: 54820    Symbol (Name): NDE1 (nudE nuclear distribution gene E homolog 1 (A. nidulans))
Ortholog Status:The human GeneID 54820 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Nde1
Original ID2:AW120739
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_023317.2NP_075806.2NC_000082.5 range: 14169567..14192658
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005813centrosomeCellular ComponentIDA (11163258|15473967)
GO:0005819spindleCellular ComponentIDA (15473967)
GO:0005856cytoskeletonCellular ComponentIEA
GO:0005874microtubuleCellular ComponentIEA
GO:0031616spindle pole centrosomeCellular ComponentIDA (15473967)
GO:0042802identical protein bindingMolecular FunctionIPI (15571978)
GO:0008017microtubule bindingMolecular FunctionIMP (15473967)
GO:0051298centrosome duplicationBiological ProcessIMP (15473967)
GO:0030900forebrain developmentBiological ProcessIMP (15473967)
GO:0030154cell differentiationBiological ProcessIEA
GO:0047496vesicle transport along microtubuleBiological ProcessIGI (16107726)
GO:0007405neuroblast proliferationBiological ProcessIMP (15473967)
GO:0007399nervous system developmentBiological ProcessIEA
GO:0007275multicellular organismal developmentBiological ProcessIEA
GO:0007067mitosisBiological ProcessIEA
GO:0007049cell cycleBiological ProcessIEA
GO:0007020microtubule nucleationBiological ProcessIDA (11163258)
GO:0051301cell divisionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:67203
MGI:
Ensembl:ENSMUSG00000022678
dbSNP:Nde1
AceView:Nde1